LOCUS       NM_001013641            1443 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens transmembrane protein 82 (TMEM82), mRNA.
ACCESSION   NM_001013641 XM_371222
VERSION     NM_001013641.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1443)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS One 7 (12), e51954 (2012)
   PUBMED   23251661
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC137239.1 and AL450998.19.
            
            On Nov 23, 2018 this sequence version replaced NM_001013641.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279837.5101.1, BC137239.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1970526
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375782.2/ ENSP00000364938.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1258              BC137239.1         8-1265
            1259-1443           AL450998.19        25034-25218
FEATURES             Location/Qualifiers
     source          1..1443
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..1443
                     /gene="TMEM82"
                     /note="transmembrane protein 82"
                     /db_xref="GeneID:388595"
                     /db_xref="HGNC:HGNC:32350"
     exon            1..149
                     /gene="TMEM82"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..1093
                     /gene="TMEM82"
                     /codon_start=1
                     /product="transmembrane protein 82"
                     /protein_id="NP_001013663.1"
                     /db_xref="CCDS:CCDS30608.1"
                     /db_xref="GeneID:388595"
                     /db_xref="HGNC:HGNC:32350"
                     /translation="MFSLPSLPSWLPGLPSLEWGSSLLDSLLQGLIGALGVLVLNSLL
                     KVYFFVGCANDPQRRPEKERLRAQWASLETVHLAGLALFLTVVGSRVAALVVLEFSLR
                     AVSTLLSLGKGSQGAAERLQLYLLCQYSLGCGLTCGLSFLQEGAPHRTLNLLLSLGLA
                     TLLGLGARRLHRHVCRLYELHSSQRYCGVCLGLLAHAHGLPQLLGRALAIAFAVGDLA
                     AVALINQDFLTTSEAMRFWTPLTICYTLLVIYMQEEQRQHPGLQSQVQTVLVRMGGLF
                     VLLLTVGRWLDLLGILVSLLGELWCLVGVRTLLDLCQIQDFPSQRPPVSTPSQPLPSA
                     PQSQSSAPS"
     exon            150..222
                     /gene="TMEM82"
                     /inference="alignment:Splign:2.1.0"
     exon            223..397
                     /gene="TMEM82"
                     /inference="alignment:Splign:2.1.0"
     exon            398..818
                     /gene="TMEM82"
                     /inference="alignment:Splign:2.1.0"
     exon            819..1006
                     /gene="TMEM82"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1443
                     /gene="TMEM82"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1421..1426
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM82"
                     /note="hexamer: AATAAA"
     polyA_site      1443
                     /gene="TMEM82"
                     /note="major polyA site"
ORIGIN      
        1 gtgacgttgg tctgtcctta cgcagacctg gccggaggct ggggctcctt ccggggctgc
       61 catgttctct cttccatccc tcccctcctg gctccccggc ctcccctccc tcgagtgggg
      121 ctctagcctc cttgactccc tcctgcaagg cctgatcggg gcccttggag tcttggtcct
      181 gaacagcctc ctgaaagttt acttcttcgt gggctgtgcc aatgacccgc agcggcgacc
      241 cgaaaaggag cggcttcggg cccagtgggc ctccctggaa acggtgcacc tggcagggct
      301 ggccctgttt ctgacggtcg tggggtcccg ggtggctgcc ctcgtggtgc tcgagttctc
      361 cctccgggcc gtgtccacgc tgctgtccct gggcaagggc tcccagggtg ccgccgagag
      421 gctgcagctc tacctgctgt gccagtactc gctgggctgc gggctgacct gtggcctgag
      481 cttcctgcag gagggcgccc ctcaccgcac gctgaacctg ctgctgagcc tcgggctggc
      541 cacgctgctg ggcctgggtg cccggcgcct ccaccgccac gtctgccgcc tctacgagct
      601 gcacagcagc cagcgctact gtggggtgtg cctgggcctg ctggcccatg cacatggcct
      661 cccccagctg ctgggccgtg ccctggccat agcctttgcc gtgggtgacc tggcagctgt
      721 ggccctcatc aaccaggact tcctgaccac ctcggaggcc atgcggttct ggacaccgct
      781 caccatctgc tacacgctgc tggtcatcta catgcaggag gagcagcggc agcaccccgg
      841 cctgcagagc caggtgcaga cggtgctggt gcgcatgggc ggcctcttcg tgctgctgct
      901 gactgtgggt cgctggctgg acctgctggg catccttgtc tccctactgg gcgagctctg
      961 gtgtctcgtg ggcgtccgca ccctgcttga cctctgccag atacaggatt ttccatccca
     1021 gaggcctcca gtgtcaacac caagccagcc cctgccctcg gcaccccagt cccagagttc
     1081 ggccccctct tgacctgcct cagggaggat ctggagtctg tctcaagccc actagcctga
     1141 tctccgaggc cttgacccca gggcgatgcc tggaggcaga gtggcagagc tggcctcctg
     1201 cccagagctc agcacaggcc ctgggagccc cgagaaggga aggcaggatt tggggatggg
     1261 agcctctgga gaggggacac ctggggaccc ctggttgaac cctctttttc ttggggtggg
     1321 caatgatgca gcctctcaga cctgccttcc tgggcagggg tgggggtgca tcctcaggag
     1381 ggctccccct ttactggtct cccttccctt ctccatgaac aataaagacg atgtctttct
     1441 caa
//
