LOCUS       NM_020431               5363 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens transmembrane protein 63C (TMEM63C), mRNA.
ACCESSION   NM_020431 XM_041116
VERSION     NM_020431.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5363)
  AUTHORS   Tabara,L.C., Al-Salmi,F., Maroofian,R., Al-Futaisi,A.M.,
            Al-Murshedi,F., Kennedy,J., Day,J.O., Courtin,T., Al-Khayat,A.,
            Galedari,H., Mazaheri,N., Protasoni,M., Johnson,M., Leslie,J.S.,
            Salter,C.G., Rawlins,L.E., Fasham,J., Al-Maawali,A., Voutsina,N.,
            Charles,P., Harrold,L., Keren,B., Kunji,E.R.S., Vona,B.,
            Jelodar,G., Sedaghat,A., Shariati,G., Houlden,H., Crosby,A.H.,
            Prudent,J. and Baple,E.L.
  TITLE     TMEM63C mutations cause mitochondrial morphology defects and
            underlie hereditary spastic paraplegia
  JOURNAL   Brain 145 (9), 3095-3107 (2022)
   PUBMED   35718349
  REMARK    GeneRIF: TMEM63C mutations cause mitochondrial morphology defects
            and underlie hereditary spastic paraplegia.
            Erratum:[Brain. 2022 Oct 21;145(10):e103. doi:
            10.1093/brain/awac254.. PMID: 36076346]
REFERENCE   2  (bases 1 to 5363)
  AUTHORS   Eisenreich,A., Orphal,M., Bohme,K. and Kreutz,R.
  TITLE     Tmem63c is a potential pro-survival factor in angiotensin
            II-treated human podocytes
  JOURNAL   Life Sci 258, 118175 (2020)
   PUBMED   32750436
  REMARK    GeneRIF: Tmem63c is a potential pro-survival factor in angiotensin
            II-treated human podocytes.
REFERENCE   3  (bases 1 to 5363)
  AUTHORS   Orphal,M., Gillespie,A., Bohme,K., Subrova,J., Eisenreich,A. and
            Kreutz,R.
  TITLE     TMEM63C, a Potential Novel Target for Albuminuria Development, Is
            Regulated by MicroRNA-564 and Transforming Growth Factor beta in
            Human Renal Cells
  JOURNAL   Kidney Blood Press Res 45 (6), 850-862 (2020)
   PUBMED   33080601
  REMARK    GeneRIF: TMEM63C, a Potential Novel Target for Albuminuria
            Development, Is Regulated by MicroRNA-564 and Transforming Growth
            Factor beta in Human Renal Cells.
REFERENCE   4  (bases 1 to 5363)
  AUTHORS   Zhao,X., Yan,X., Liu,Y., Zhang,P. and Ni,X.
  TITLE     Co-expression of mouse TMEM63A, TMEM63B and TMEM63C confers
            hyperosmolarity activated ion currents in HEK293 cells
  JOURNAL   Cell Biochem Funct 34 (4), 238-241 (2016)
   PUBMED   27045885
REFERENCE   5  (bases 1 to 5363)
  AUTHORS   Hou,C., Tian,W., Kleist,T., He,K., Garcia,V., Bai,F., Hao,Y.,
            Luan,S. and Li,L.
  TITLE     DUF221 proteins are a family of osmosensitive calcium-permeable
            cation channels conserved across eukaryotes
  JOURNAL   Cell Res 24 (5), 632-635 (2014)
   PUBMED   24503647
REFERENCE   6  (bases 1 to 5363)
  AUTHORS   Lee,H.J., Woo,H.G., Greenwood,T.A., Kripke,D.F. and Kelsoe,J.R.
  TITLE     A genome-wide association study of seasonal pattern mania
            identifies NF1A as a possible susceptibility gene for bipolar
            disorder
  JOURNAL   J Affect Disord 145 (2), 200-207 (2013)
   PUBMED   22925353
REFERENCE   7  (bases 1 to 5363)
  AUTHORS   Heilig,R., Eckenberg,R., Petit,J.L., Fonknechten,N., Da Silva,C.,
            Cattolico,L., Levy,M., Barbe,V., de Berardinis,V., Ureta-Vidal,A.,
            Pelletier,E., Vico,V., Anthouard,V., Rowen,L., Madan,A., Qin,S.,
            Sun,H., Du,H., Pepin,K., Artiguenave,F., Robert,C., Cruaud,C.,
            Bruls,T., Jaillon,O., Friedlander,L., Samson,G., Brottier,P.,
            Cure,S., Segurens,B., Aniere,F., Samain,S., Crespeau,H., Abbasi,N.,
            Aiach,N., Boscus,D., Dickhoff,R., Dors,M., Dubois,I., Friedman,C.,
            Gouyvenoux,M., James,R., Madan,A., Mairey-Estrada,B., Mangenot,S.,
            Martins,N., Menard,M., Oztas,S., Ratcliffe,A., Shaffer,T.,
            Trask,B., Vacherie,B., Bellemere,C., Belser,C., Besnard-Gonnet,M.,
            Bartol-Mavel,D., Boutard,M., Briez-Silla,S., Combette,S.,
            Dufosse-Laurent,V., Ferron,C., Lechaplais,C., Louesse,C.,
            Muselet,D., Magdelenat,G., Pateau,E., Petit,E.,
            Sirvain-Trukniewicz,P., Trybou,A., Vega-Czarny,N., Bataille,E.,
            Bluet,E., Bordelais,I., Dubois,M., Dumont,C., Guerin,T.,
            Haffray,S., Hammadi,R., Muanga,J., Pellouin,V., Robert,D.,
            Wunderle,E., Gauguet,G., Roy,A., Sainte-Marthe,L., Verdier,J.,
            Verdier-Discala,C., Hillier,L., Fulton,L., McPherson,J.,
            Matsuda,F., Wilson,R., Scarpelli,C., Gyapay,G., Wincker,P.,
            Saurin,W., Quetier,F., Waterston,R., Hood,L. and Weissenbach,J.
  TITLE     The DNA sequence and analysis of human chromosome 14
  JOURNAL   Nature 421 (6923), 601-607 (2003)
   PUBMED   12508121
  REMARK    Erratum:[Nature. 2023 Aug;620(7973):E17. doi:
            10.1038/s41586-023-06403-y.. PMID: 37491470]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL537279.3, AK125159.1, BC136613.1, KF455952.1, AC007375.6,
            BX248759.1 and AL137278.1.
            
            On Nov 22, 2018 this sequence version replaced NM_020431.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK125159.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2145743 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000298351.5/ ENSP00000298351.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                AL537279.3         176-204
            30-137              AK125159.1         1-108
            138-559             BC136613.1         59-480
            560-560             KF455952.1         174-174
            561-561             AC007375.6         114422-114422
            562-805             BC136613.1         483-726
            806-1253            BX248759.1         192-639
            1254-4268           BC136613.1         1175-4189
            4269-5363           AL137278.1         931-2025
FEATURES             Location/Qualifiers
     source          1..5363
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q24.3"
     gene            1..5363
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /note="transmembrane protein 63C"
                     /db_xref="GeneID:57156"
                     /db_xref="HGNC:HGNC:23787"
                     /db_xref="MIM:619953"
     exon            1..97
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            98..160
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            161..323
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..2594
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /note="calcium permeable stress-gated cation channel 1
                     homolog"
                     /codon_start=1
                     /product="calcium permeable stress-gated cation channel 1"
                     /protein_id="NP_065164.2"
                     /db_xref="CCDS:CCDS45141.1"
                     /db_xref="GeneID:57156"
                     /db_xref="HGNC:HGNC:23787"
                     /db_xref="MIM:619953"
                     /translation="MSASPDDLSTGGRLQNMTVDECFQSRNTVLQGQPFGGVPTVLCL
                     NIALWVLVLVVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKTSPSETSLEMERR
                     DKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYT
                     GSVLDWSSHFARTTIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKV
                     TRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGR
                     LFYTAKAKKTGKVMIRIHPCARLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNR
                     VPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGVQPQQSSVTTIVKSYYWRVTMAPHPK
                     DIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTIDMYNVTRPIEKLQNPI
                     VTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSM
                     GLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGS
                     LFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFG
                     LLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWMLFFSILRLGSL
                     HAITIFSLSTLLIAMVIAFVGIFLGKLRMVADYEPEEEEIQTVFDMEPSSTSSTPTSL
                     LYVATVLQEPELNLTPASSPARHTYGTMNNQPEEGEEESGLRGFARELDSAQFQEGLE
                     LEGQNQYH"
     exon            324..403
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            404..485
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            486..523
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            524..666
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            667..715
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            716..824
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            825..898
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            899..979
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1103
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1237
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1360
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1514
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1621
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..1708
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1774
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            1775..1937
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            1938..2043
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            2044..2211
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            2212..2321
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            2322..2393
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     exon            2394..5363
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5341..5346
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /note="hexamer: AATAAA"
     polyA_site      5363
                     /gene="TMEM63C"
                     /gene_synonym="C14orf171; CSC1; hsCSC1; SPG87"
                     /note="major polyA site"
ORIGIN      
        1 agtctcctcc caggtgggga gcgtggagcc tgtcactgca gcctggcggc ctgagcgccg
       61 agcctggggc tggggccgcg gtgctgagga cgcaaatcag ccccgtagct gggtggagcc
      121 tccgggcctg acgtggacct tcactggaga agtgactcag ggatcctccc aggatgtctg
      181 cctcaccaga cgacctgagt acagggggaa ggttacagaa catgacagtg gatgaatgct
      241 tccagtctcg gaacaccgtc ctccaggggc agccctttgg gggtgtcccc accgtgctgt
      301 gcctcaacat cgccctgtgg gtgctcgtcc ttgtggttta ctccttcctc cggaaagctg
      361 cgtgggacta tgggcgcctg gctctgctga tacacaatga cagcctgacc tcgctgatct
      421 atggggagca gagcgagaag acatctccct cggagacttc cttggagatg gaacgcagag
      481 acaagggatt ctgttcctgg ttcttcaaca gcataacaat gaaggacgag gatctgatta
      541 acaagtgtgg ggacgacgcg cgcatctaca tcgtgttcca gtaccacctc atcatctttg
      601 tgctcatcat ctgtatcccc tccctgggca tcattttgcc catcaactat actggatctg
      661 ttctggactg gagcagtcac tttgctcgga ccaccattgt caatgtctcc acagagagca
      721 agctcctgtg gctgcatagc ctgctgtcct tcttctactt catcaccaac ttcatgttca
      781 tggctcatca ctgcctgggg tttgcaccca ggaatagcca aaaggtcaca aggacactaa
      841 tgatcaccta tgtgcccaag gacattgaag acccagaact catcattaag cattttcacg
      901 aggcctatcc aggcagtgtc gtgacaagag tccacttctg ctacgacgtc aggaacctga
      961 tcgacttgga cgatcagagg cgccatgcca tgcggggccg gcttttctat acagccaagg
     1021 ccaagaagac tgggaaggtg atgatcagga tccacccctg tgcccgcctg tgcttctgca
     1081 agtgctggac ctgcttcaag gaggtggatg cagagcagta ttacagcgag ctagaggagc
     1141 agctaacgga cgagttcaac gccgagctca accgcgtgcc gctcaagcgg ctggacctga
     1201 tctttgtcac cttccaggac tccaggatgg ccaagcgtgt ccgtaaggat tacaagtatg
     1261 tccagtgtgg tgtgcaaccc cagcagtcct cagtgaccac catcgtcaaa tcatattact
     1321 ggagggtcac tatggcccca caccccaaag acattatttg gaaacacctg tctgtccgcc
     1381 gcttcttttg gtgggcccgc tttatcgcaa tcaacacctt cctcttcttc ctcttcttct
     1441 ttctcaccac gcctgccatc atcatgaaca ctatcgacat gtacaacgtc acccgcccca
     1501 tcgagaagct gcagaaccca attgtgaccc agttcttccc ctctgtgatg ctctggggct
     1561 tcacagtgat actgcctctg attgtctact tctccgcctt cctcgaggcc cactggacca
     1621 gatcaagtca gaatctggtc atggtgcaca agtgctacat ctttctggtg ttcatggtag
     1681 tcattctgcc ctctatggga ctgaccagtt tggatgtctt tctccgctgg ctctttgaca
     1741 tctactatct agagcaagca tccatcaggt tccagtgtgt gttcctgcca gacaacggcg
     1801 ccttctttgt caactacgtg atcacggcag ctttacttgg cacaggcatg gagctgctgc
     1861 gtctggggtc actcttctgc tacagcaccc gcctcttctt ctctagatca gagccagaga
     1921 gagtcaacat cagaaagaac caggccatag acttccagtt tgggcgtgag tatgcgtgga
     1981 tgatgaacgt gttcagcgtg gtgatggcgt acagcatcac ttgccccatc attgtgcctt
     2041 ttgggttgct ctacctgtgc atgaagcact tgacggatcg ctataacatg tactactcct
     2101 ttgcacccac caaactgaac gagcagatcc acatggctgc cgtctcccag gccatctttg
     2161 cgccactctt gggtctgttc tggatgctgt tcttctccat cctgcggttg ggttctctcc
     2221 acgccatcac catcttttcc ctgtccaccc tcctcattgc catggtgatt gcctttgttg
     2281 gcatttttct ggggaagctt cggatggttg ccgactacga gcccgaggag gaggagatcc
     2341 agacagtgtt tgacatggag ccaagcagca cctcctccac gcccacctcc ctcctgtatg
     2401 tggccaccgt gctgcaagaa ccggagttga atctgacccc cgcctcctcc ccagccaggc
     2461 acacctatgg caccatgaac aaccagccgg aagagggaga agaagagagt ggtctgaggg
     2521 gctttgcgag ggagctagac tcggcccagt tccaggaagg gctggaactg gagggccaga
     2581 accagtacca ctgaccggga cctgaggcct ccactggcga cttgttgagg ggtcagggga
     2641 gggcctggca aggggaggca ggagggtggc ctggacctcc ccactacctc ctgcagactt
     2701 tgagaagccc acagtggaga catccaccac cccagccatg ggccatacgg gggtcctgac
     2761 ctgctgcccg gctggaactg ggggtgctcg gcagtgctga aggagcctgg gaagggatgg
     2821 gaggatacag gcaagcacat gtcttgagag aggtggctgg agccccggca cagagactga
     2881 acgctggggt cccttcctgg gaccaagatg gagaaggtgt tcctaaggga ggagacagaa
     2941 ggaggctgcc gaaggctctg tggggtcatc accactctgc atcagctgcc cttccaagga
     3001 gcttctgctg ctgctcctcc tcccagcccc ggcccattcc tcccctgcag tctgaggagg
     3061 caaaggtatg tgcacggggc acattgacag gacacggagg accacctcat cacagggttc
     3121 cctgcatggg gatctgtaaa gagaaagttt ctgcacccac cagagcaaga gccaactgaa
     3181 agcgtagacc tgagaagagg taactcagcc ccttcctgct cctctgccct catcagatgt
     3241 ccccaggagc agcagggcag aggcccttct ttctattctt acaagggtag ctagagcgtg
     3301 atcactcagg gctcatcaaa tgagactcgt gtgcattttt cagaaggaaa ccttggttag
     3361 tccttgctgg gtaacacaaa gtggggtgag acgacagaag ccgaattcat ggaagggggg
     3421 tcttctcccc aaaactctgt gtggtgggaa accagctata cctccccaag ccccagggcc
     3481 taaagagaag acccccgaag ccaaagatgt ggccacttaa aagcgtctcc tgcctcctac
     3541 ccaactgagt gcctgggccc ccagcttggc caagatgggc agtacgttag ggtaagaacc
     3601 ccatgcttca aacttaagga ctgaccatca cctgcgtccc aagtaggacc cttcctccct
     3661 tctcggggct gcccctgcac cctgccttga agaccaccca agcggcctcc agtgtgggcc
     3721 tggtccagac attgcagatg cttcaaccgt gatgtcgccc caggcctgcc aggggtgtgg
     3781 tggaggggaa ggccacgtgc tccagggaga agccctttct ggagaagcaa ggctgtcctc
     3841 ccagggctgc cactaccaga gacctggggg agctgaattc cgaacagtga tggtgacact
     3901 cagcaccttt gccacagccg gggggaaccg gcttctgcct ctgggatggg ctctcatcag
     3961 gaccaccgtg cagcccagcc agggaggaca tgagaagggc cagtgggggc ctcaatgaac
     4021 cagaacaagc caagctgaat ggggtctgtg tgctccaggg ccctcttcag ccccctcccc
     4081 caaaggtctg ggtccctgcc accaacctac tgaaggccgg cccccggctc acctcacctg
     4141 agcacctgca ccaggcccca ggcacatggc tgccctgaac tcagatcacc tagaccttgt
     4201 ccctgcccca cctttgcccc atcctagccc cagaagctcc aagcttcacc gcaggtgaga
     4261 aattgtgctc aatgggcaga aactgctata cccccagggc atggcccaca ttttggcatg
     4321 agggtgtctt tccagagagc ttgggttggc tggagagagg ctgtctttcc cattccttgt
     4381 ccagctagga ataaagggga aatggtccta gcctggcccc tacacaccca ggtcccacag
     4441 gccccctccc cactggaatt tcaccaacca acaaggggaa agtacgctgt tacagcatag
     4501 cggtcaggcc cagcaggagc ttggcacatg atggggaggt ggccagctcc aggccctgcc
     4561 cgaccccatc atgtgtattt ggtgtatggg gtgtgggggg tcacaccaga agctggcctg
     4621 gggtctcttc tttgctggac acagctccct ggcccctgcc cccagcccct gcagcccctg
     4681 ccggactgtg gaagccacat atgggaaaag tcctggcaga caatgtggcg ggatgactgg
     4741 gggcttctcc ctctgaacct gggtccagtg tagcctggct ctgagagaag gtggtgagca
     4801 tgtggagaag gttccatagt ccactcttag gggaaccagc aaagcctcat ggcagttggc
     4861 tccatctgga cctcccatgg tcactacagg atggtggagc agggggcatc ttttagcctc
     4921 cccccgccac cacatccagg ccctctcagg cacctcctgc ctcagcccac acctgcctca
     4981 cccattgccc ccctcccccc acctactgcc atcccactcc tctgccagcc acttcccagc
     5041 cgccccaccc cactccatcc accaaatcac ctcctgactt aatcctttct ggaaggagct
     5101 gccgcccagg aaccggtatt gcctagagcc tccaggaggg gccctcctca ggcctccagt
     5161 ggccccatgc ccacctgcct gaccctccac tgcccctgga agcaaagtgc ctatcagcag
     5221 cgttgcgtcc tctggggccc ccggtcgggg gggagggggt gtgggctaac cttggccacc
     5281 accacaaaag gaatgtgcca gaatgctgaa ccttcttgtt aatgctatga ccgtgccttg
     5341 aataaacaag tcctcccaac ctc
//
