LOCUS       XM_047440989            2274 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transmembrane protein 50B (TMEM50B),
            transcript variant X3, mRNA.
ACCESSION   XM_047440989
VERSION     XM_047440989.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000021.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2274
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
     gene            1..2274
                     /gene="TMEM50B"
                     /gene_synonym="C21orf4; HCVP7TP3"
                     /note="transmembrane protein 50B; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 26 ESTs, 348 long SRA reads, 1 Protein, and 94%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 93 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:757"
                     /db_xref="HGNC:HGNC:1280"
                     /db_xref="MIM:617894"
     CDS             179..559
                     /gene="TMEM50B"
                     /gene_synonym="C21orf4; HCVP7TP3"
                     /codon_start=1
                     /product="transmembrane protein 50B isoform X3"
                     /protein_id="XP_047296945.1"
                     /db_xref="GeneID:757"
                     /db_xref="HGNC:HGNC:1280"
                     /db_xref="MIM:617894"
                     /translation="MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDA
                     AVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIG
                     FMLMFGSLIASMWILFGAYVTQTL"
     polyA_site      2274
                     /gene="TMEM50B"
                     /gene_synonym="C21orf4; HCVP7TP3"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gctctatcct cgcgtctgct cccagctccg ggctcccggg gctgaggtgg agccgcggga
       61 cgccggcagg gttgtggcgc agcagtctcc ttcctgcgcg cgcgcctgaa gtcggcgtgg
      121 gcgtttgagg aagctgggat acagcattta atgaaaaatt tatgcttaag aagtaaaaat
      181 ggcaggcttc ctagataatt ttcgttggcc agaatgtgaa tgtattgact ggagtgagag
      241 aagaaatgct gtggcatctg ttgtcgcagg tatattgttt tttacaggct ggtggataat
      301 gattgatgca gctgtggtgt atcctaagcc agaacagttg aaccatgcct ttcacacatg
      361 tggtgtattt tccacattgg ctttcttcat gataaatgct gtatccaatg ctcaggtgag
      421 aggtgatagc tatgaaagcg gctgtttagg aagaacaggt gctcgagttt ggcttttcat
      481 tggtttcatg ttgatgtttg ggtcacttat tgcttccatg tggattcttt ttggtgcata
      541 tgttacccaa acactctgat ctacaaattt ggaagaaccg aagagctatg gacctgagat
      601 cacttcttaa gtcacatttt ccttttgtta tattctgttt gtagataggt tttttatctc
      661 tcagtacaca ttgccaaatg gagtagattg tacattaaat gttttgtttc tttacatttt
      721 tatgttctga gttttgaaat agttttatga aatttcttta tttttcattg catagactgt
      781 taatatgtat ataatacaag actatatgaa ttggataatg agtatcagtt ttttattcct
      841 gagatttaga acttgatcta ctccctgagc cagggttaca tcatcttgtc attttagaag
      901 taaccactct tgtctctctg gctgggcacg gtggctcatg cctgtaatcc cagcactttg
      961 ggaggccgag gcgggccgat tgcttgaggt caagtgtttg agaccagcct ggccaacatg
     1021 gcgaaacccc atctactaaa aatacaaaaa ttagccaggc atggtggtgg gtgcctgtaa
     1081 tcccaactac ctaggaggct gaggcaggag aatcgcttga acccgggggg cagaggttgt
     1141 agtgagctga gtttgcgcca ctgcactcta gcctggggga gaaagtgaaa ctccctctca
     1201 aaaaaaagaa ggaccactct cagtatctga tttctgaaga tgtacaaaaa aatatagctt
     1261 catatatcta gaatgagcac tgagccataa aaggttttca gcaagttgta acttattttg
     1321 gcctaaaaat gaggtttttt tggtaaagaa aaaatatttg ttcttatgta ttgaagaagt
     1381 gtacttttat ataatgattt tttaaatgcc caaaggacta gtttgaaagc ttcttttaaa
     1441 aagaattcct ctaatatgac tttatgtgag aagggataat acatgatcaa ataaactcag
     1501 ttttttatgg ttactgtaaa aagactgtgt aaggcagctc agcaccatgc ttctcgtaaa
     1561 agcagcttca aatatccact ggggttatct tttgacaact tgccattatc tgatgttaca
     1621 caattcaata gcaagcaagt ttgagacaat cgcagtttaa aagcatgaac catttaacaa
     1681 aaagtggaat aattaaagat aaagcacttc ttcccaaagg gaattatcac ctagtgaaaa
     1741 attatgcatt tcatctactc agttaccgac tgcaagtctc tcctcgctct agctctcaag
     1801 ctttgggtga atattcctgt gaaatatatc ttcaacttga aagttcatac tccaatcaaa
     1861 aactcctttt actgagtttg cagtactgta tttgcactgt ttgtattcct ctgggccctt
     1921 attgctactt ttgctttcct ttgttacaca gattttgtgt tgcacttttt ctccagaggg
     1981 gtgttgtaga gccttggttg tatgaataat accagtggta gtgtccacgg ctctaatgta
     2041 agcccatttg gcatcactcc tctcctctct cttgagagga tttcttgtgc acagagtatg
     2101 aagcagttgt ggagcgctgt gcctttgtca agataccatc ttgtttgatg acttctttct
     2161 ttgctgtttt ttcttcaaaa tgttagtaag ctctgtcatg cttctagcaa attgtaagac
     2221 taattatttg tttccacctc ataacctgtt gcaataaata ttacttctca taca
//
