LOCUS       XM_011529746            3202 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transmembrane protein 50B (TMEM50B),
            transcript variant X1, mRNA.
ACCESSION   XM_011529746
VERSION     XM_011529746.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000021.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011529746.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3202
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
     gene            1..3202
                     /gene="TMEM50B"
                     /gene_synonym="C21orf4; HCVP7TP3"
                     /note="transmembrane protein 50B; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 8
                     mRNAs, 50 ESTs, 2138 long SRA reads, 7 Proteins, and 95%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 124 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:757"
                     /db_xref="HGNC:HGNC:1280"
                     /db_xref="MIM:617894"
     CDS             179..655
                     /gene="TMEM50B"
                     /gene_synonym="C21orf4; HCVP7TP3"
                     /codon_start=1
                     /product="transmembrane protein 50B isoform X1"
                     /protein_id="XP_011528048.1"
                     /db_xref="GeneID:757"
                     /db_xref="HGNC:HGNC:1280"
                     /db_xref="MIM:617894"
                     /translation="MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDA
                     AVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIG
                     FMLMFGSLIASMWILFGAYVTQNTDVYPGLAVFFQNALIFFSTLIYKFGRTEELWT"
ORIGIN      
        1 gctctatcct cgcgtctgct cccagctccg ggctcccggg gctgaggtgg agccgcggga
       61 cgccggcagg gttgtggcgc agcagtctcc ttcctgcgcg cgcgcctgaa gtcggcgtgg
      121 gcgtttgagg aagctgggat acagcattta atgaaaaatt tatgcttaag aagtaaaaat
      181 ggcaggcttc ctagataatt ttcgttggcc agaatgtgaa tgtattgact ggagtgagag
      241 aagaaatgct gtggcatctg ttgtcgcagg tatattgttt tttacaggct ggtggataat
      301 gattgatgca gctgtggtgt atcctaagcc agaacagttg aaccatgcct ttcacacatg
      361 tggtgtattt tccacattgg ctttcttcat gataaatgct gtatccaatg ctcaggtgag
      421 aggtgatagc tatgaaagcg gctgtttagg aagaacaggt gctcgagttt ggcttttcat
      481 tggtttcatg ttgatgtttg ggtcacttat tgcttccatg tggattcttt ttggtgcata
      541 tgttacccaa aatactgatg tttatccggg actagctgtg ttttttcaaa atgcacttat
      601 attttttagc actctgatct acaaatttgg aagaaccgaa gagctatgga cctgagatca
      661 cttcttaagt cacattttcc ttttgttata ttctgtttgt agataggttt tttatctctc
      721 agtacacatt gccaaatgga gtagattgta cattaaatgt tttgtttctt tacattttta
      781 tgttctgagt tttgaaatag ttttatgaaa tttctttatt tttcattgca tagactgtta
      841 atatgtatat aatacaagac tatatgaatt ggataatgag tatcagtttt ttattcctga
      901 gatttagaac ttgatctact ccctgagcca gggttacatc atcttgtcat tttagaagta
      961 accactcttg tctctctggc tgggcacggt ggctcatgcc tgtaatccca gcactttggg
     1021 aggccgaggc gggccgattg cttgaggtca agtgtttgag accagcctgg ccaacatggc
     1081 gaaaccccat ctactaaaaa tacaaaaatt agccaggcat ggtggtgggt gcctgtaatc
     1141 ccaactacct aggaggctga ggcaggagaa tcgcttgaac ccggggggca gaggttgtag
     1201 tgagctgagt ttgcgccact gcactctagc ctgggggaga aagtgaaact ccctctcaaa
     1261 aaaaagaagg accactctca gtatctgatt tctgaagatg tacaaaaaaa tatagcttca
     1321 tatatctaga atgagcactg agccataaaa ggttttcagc aagttgtaac ttattttggc
     1381 ctaaaaatga ggtttttttg gtaaagaaaa aatatttgtt cttatgtatt gaagaagtgt
     1441 acttttatat aatgattttt taaatgccca aaggactagt ttgaaagctt cttttaaaaa
     1501 gaattcctct aatatgactt tatgtgagaa gggataatac atgatcaaat aaactcagtt
     1561 ttttatggtt actgtaaaaa gactgtgtaa ggcagctcag caccatgctt ctcgtaaaag
     1621 cagcttcaaa tatccactgg ggttatcttt tgacaacttg ccattatctg atgttacaca
     1681 attcaatagc aagcaagttt gagacaatcg cagtttaaaa gcatgaacca tttaacaaaa
     1741 agtggaataa ttaaagataa agcacttctt cccaaaggga attatcacct agtgaaaaat
     1801 tatgcatttc atctactcag ttaccgactg caagtctctc ctcgctctag ctctcaagct
     1861 ttgggtgaat attcctgtga aatatatctt caacttgaaa gttcatactc caatcaaaaa
     1921 ctccttttac tgagtttgca gtactgtatt tgcactgttt gtattcctct gggcccttat
     1981 tgctactttt gctttccttt gttacacaga ttttgtgttg cactttttct ccagaggggt
     2041 gttgtagagc cttggttgta tgaataatac cagtggtagt gtccacggct ctaatgtaag
     2101 cccatttggc atcactcctc tcctctctct tgagaggatt tcttgtgcac agagtatgaa
     2161 gcagttgtgg agcgctgtgc ctttgtcaag ataccatctt gtttgatgac ttctttcttt
     2221 gctgtttttt cttcaaaatg ttagtaagct ctgtcatgct tctagcaaat tgtaagacta
     2281 attatttgtt tccacctcat aacctgttgc aataaatatt acttctcata cagtttaata
     2341 ttgttgtttg ttggagaaaa tgaaccataa aaattgattt gctgttcagt tttcaattat
     2401 tcaagtatac ccaattaaag atgcagttat gtttataaaa taagaagaaa tagacttgta
     2461 aaatgcttat gtgagggtta ttgaaggttt ccctgaagac tgactggaaa tggtggctgt
     2521 ttttttctat ttctgactct gccatgaatt tttttttttt tttttaaaga caatatctca
     2581 ctctgttgcc taggctggag tgcagtggtg caaccacagc tcactgcacc ttcaaatgct
     2641 ggagctcagg caatcctctt acctccgctt tccaagcagc tgggaccaca gatgtatcct
     2701 ccactcctcg ctggccacca tcctgctgcc caacagaaga agctcttctg tctccgattt
     2761 cctgaacggt ctaagggagc cagtgggcta ggcccatgct ttggttcaaa gcgtttggag
     2821 aacatcttct tgctcctttt ccggaaacga gataatggac acagagtccc agacgtcatc
     2881 ctttggacca ggaagaaaca ggctcctgcc agcaccgaca gcaacgaaaa tgttcccacg
     2941 gagatcagga tgacttgctg aagctcagtg gaggctaaaa agaggacacg aaagtgaaca
     3001 gaatgatctt cctacgcaca acacaaacat cagttaatgt tccatccatg ctgcttaaag
     3061 agcattcctg tcctagtaaa atgggcaagt ccctctaccc cccaccctca cctggtatgc
     3121 ttacattaat agctaaagtc aatcctgtaa tgaaataaag caagtggtag ctgtctggta
     3181 gcctccacta ctgcaaatct ca
//
