LOCUS       NM_182541                732 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens transmembrane protein 31 (TMEM31), mRNA.
ACCESSION   NM_182541
VERSION     NM_182541.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 732)
  AUTHORS   Li,J., Zou,X., Li,C., Zhong,J., Chen,Y., Zhang,X., Qi,F., Li,M.,
            Cai,Z. and Tang,A.
  TITLE     Expression of novel cancer/testis antigen TMEM31 increases during
            metastatic melanoma progression
  JOURNAL   Oncol Lett 13 (4), 2269-2273 (2017)
   PUBMED   28454390
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK130867.1.
            
            On Nov 15, 2004 this sequence version replaced NM_182541.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: HM005598.1, AK130867.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142853
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000319560.7/ ENSP00000316940.6
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-732               AK130867.1         1-732
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.2"
     gene            1..732
                     /gene="TMEM31"
                     /note="transmembrane protein 31"
                     /db_xref="GeneID:203562"
                     /db_xref="HGNC:HGNC:28601"
                     /db_xref="MIM:301102"
     exon            1..168
                     /gene="TMEM31"
                     /inference="alignment:Splign:2.1.0"
     exon            169..293
                     /gene="TMEM31"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..698
                     /gene="TMEM31"
                     /note="testicular secretory protein Li 58"
                     /codon_start=1
                     /product="transmembrane protein 31"
                     /protein_id="NP_872347.2"
                     /db_xref="CCDS:CCDS35359.1"
                     /db_xref="GeneID:203562"
                     /db_xref="HGNC:HGNC:28601"
                     /db_xref="MIM:301102"
                     /translation="MRLTEKSEGEQQLKPNNSNAPNEDQEEEIQQSEQHTPARQRTQR
                     ADTQPSRCRLPSRRTPTTSSDRTINLLEVLPWPTEWIFNPYRLPALFELYPEFLLVFK
                     EAFHDISHCLKAQMEKIGLPIILHLFALSTLYFYKFFLPTILSLSFFILLVLLLLLFI
                     IVFILIFF"
     exon            294..732
                     /gene="TMEM31"
                     /inference="alignment:Splign:2.1.0"
     regulatory      711..716
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM31"
                     /note="hexamer: AATAAA"
     polyA_site      732
                     /gene="TMEM31"
                     /note="major polyA site"
ORIGIN      
        1 aggcagttgc gggttgcagg agttcaggaa aggaggtggg actagagtca acctggaata
       61 gctctacagt aacaatggca gcctttttgt tgctgggaca tccatacagg caacttagct
      121 ggtgaaagga ctctggattg gttggcagtc tgcttttttt tttccaaggt gatcacttta
      181 ctgtagaaga aatgaggtta acagaaaaga gtgagggaga acaacaactc aagcccaaca
      241 actctaatgc acccaatgaa gatcaagaag aagaaatcca acagtcagaa cagcatactc
      301 cagcaaggca gcgaacacaa agagcagaca cacagccatc cagatgtcga ttgccttcac
      361 gtaggacacc tacaacatcc agcgacagaa cgatcaacct tcttgaagtc cttccgtggc
      421 ctactgagtg gattttcaac ccctatcgat tgcctgctct ttttgagctt tatcctgaat
      481 ttcttctggt gtttaaagaa gccttccatg acatatccca ttgtctgaaa gcccagatgg
      541 aaaagatcgg actgcccatc atactccacc tcttcgcact ctccaccctc tacttctaca
      601 agtttttcct tcctacaatt ctttcccttt ctttctttat tcttcttgta cttctgcttc
      661 tgctttttat tattgtcttc attctgatct tcttctgatt cttttgtttc aataaacagc
      721 aatgagcatg aa
//
