LOCUS       NM_001351003            4153 bp    mRNA    linear   PRI 04-OCT-2024
DEFINITION  Homo sapiens transmembrane protein 272 (TMEM272), transcript
            variant 1, mRNA.
ACCESSION   NM_001351003 NR_027047 XM_001721162 XM_001723292 XM_001725783
            XR_017830 XR_017831 XR_041498
VERSION     NM_001351003.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4153)
  AUTHORS   Kimura,K., Wakamatsu,A., Suzuki,Y., Ota,T., Nishikawa,T.,
            Yamashita,R., Yamamoto,J., Sekine,M., Tsuritani,K., Wakaguri,H.,
            Ishii,S., Sugiyama,T., Saito,K., Isono,Y., Irie,R., Kushida,N.,
            Yoneyama,T., Otsuka,R., Kanda,K., Yokoi,T., Kondo,H., Wagatsuma,M.,
            Murakawa,K., Ishida,S., Ishibashi,T., Takahashi-Fujii,A.,
            Tanase,T., Nagai,K., Kikuchi,H., Nakai,K., Isogai,T. and Sugano,S.
  TITLE     Diversification of transcriptional modulation: large-scale
            identification and characterization of putative alternative
            promoters of human genes
  JOURNAL   Genome Res 16 (1), 55-65 (2006)
   PUBMED   16344560
REFERENCE   2  (bases 1 to 4153)
  AUTHORS   Bonaldo,M.F., Lennon,G. and Soares,M.B.
  TITLE     Normalization and subtraction: two approaches to facilitate gene
            discovery
  JOURNAL   Genome Res 6 (9), 791-806 (1996)
   PUBMED   8889548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL162377.10, DA339105.1 and BM661920.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001351003.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.40292.1, DA339105.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2159607, SAMEA2161674
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000629372.3/ ENSP00000490718.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AL162377.10        74189-74213         c
            26-621              DA339105.1         1-596
            622-3692            AL162377.10        42844-45914         c
            3693-4153           BM661920.1         19-479              c
FEATURES             Location/Qualifiers
     source          1..4153
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q14.3"
     gene            1..4153
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /note="transmembrane protein 272"
                     /db_xref="GeneID:283521"
                     /db_xref="HGNC:HGNC:26737"
     exon            1..162
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /inference="alignment:Splign:2.1.0"
     exon            163..243
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..749
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /note="isoform 1 is encoded by transcript variant 1; long
                     intergenic non-protein coding RNA 282"
                     /codon_start=1
                     /product="transmembrane protein 272 isoform 1"
                     /protein_id="NP_001337932.1"
                     /db_xref="CCDS:CCDS86353.1"
                     /db_xref="GeneID:283521"
                     /db_xref="HGNC:HGNC:26737"
                     /translation="MPGGLEKTCHQCISKIASNACFVVVLCAFLALPLSMTFIGMKFL
                     EDCPIQPLIPLYLLVGGIVGTLKVSLLLYDSTRMRRLLSKAVVIDDDDDDEYPWRQNA
                     HRYYIHLLLSLFLFLWFILGNYWVFSVYLPDFLPPFQQPQDYCDKTLYLFAVGVLALS
                     HTVLVLLLLCSGCVYLCSRWRLAADED"
     exon            244..303
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /inference="alignment:Splign:2.1.0"
     exon            304..386
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /inference="alignment:Splign:2.1.0"
     exon            387..4153
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4133..4138
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /note="hexamer: AATAAA"
     polyA_site      4153
                     /gene="TMEM272"
                     /gene_synonym="LINC00282; NCRNA00282"
                     /note="major polyA site"
ORIGIN      
        1 acgagttgct gttgtgctgc aggagagaaa gggagaaaga aagcgtgcga cagggagtgg
       61 gagccccaag tcaagaggag ccccacagag gcagccctgg acttcgggac cacagaggtg
      121 ctgagtgctg cccgattctg gatcccactc tgcttagctc agaactttgt cagcgagcaa
      181 gaacaatgcc aggaggtctg gagaaaacgt gtcatcagtg catttctaaa atcgccagca
      241 atgcctgctt cgttgttgtg ctctgtgctt tcctggctct gccgctgtcc atgaccttca
      301 taggaatgaa atttttggag gactgcccta tacagcccct cattccttta tatttgctag
      361 tgggtggcat cgtcggtacc ttaaaggtgt ctctcctgtt gtacgactcc accaggatga
      421 ggcggctgct gtccaaggcc gtggtgattg atgacgatga cgatgacgaa tacccctgga
      481 ggcagaatgc gcacagatac tacatccacc tcctgctgag cctcttcctc ttcctctggt
      541 tcatcctggg aaactactgg gtcttttctg tgtacctgcc tgattttctt ccccctttcc
      601 agcagcctca ggactactgt gacaaaaccc tgtacctctt tgcagtcgga gtcctggcgc
      661 tcagtcacac tgtgctggtc ttgctcctgc tgtgcagcgg ctgtgtctac ctgtgctcca
      721 ggtggagact tgctgccgat gaagactgac agctgccttg tccagcatac catgtatgca
      781 tatgcgtgtg catgcacgcg cgtgcacaca gacacacaga cgcacacaca cacacacaca
      841 cacacaggtt cagagaaggg cataaaggta ataaaacctt ccctgaaggc atttaaaaag
      901 ccacccaaag gcactgaata taatagcaga ctaaagaaac tcttgccttc ctagacatgg
      961 ggaaatcact tctgctcttt tcagagtggg aattttgttc tcacaagagt tttcaaaggg
     1021 ataattgttt ttgagggtat gaagtgtggg aggcaaagaa tgggagacct tttcaaatca
     1081 tagtgcaatt tcaatgactg gtgcaagagc aaggttggtt gttgctactg ctgctgtcat
     1141 tcagccatgg tcaccttgaa gttatagaaa gtgcacagac tttcacacaa gatatatctt
     1201 aacttcactc gctatgatgg cttttgttat taaaaggaaa aagatattct tttagtgact
     1261 ctagctgcct tttgggaaag tgaaggagca gtctcttcca gccctatatc agataggttt
     1321 gacgtgatgg gtggaacatc ccaaggtcag ctataaaatc taacaacgtc aaagcagtag
     1381 cttccacata gggggcgggc tggcctgcta caggcattgc ggagtgcagc gccgtgtgca
     1441 ccgtgtgccg ctgctgcagg ttctttgctt ggccttgagt ctgtctctgc ctctggctat
     1501 tcaagtacct ctctatgatc tgcggctggc tgggtggcat aaaccagttt tgtatgtttc
     1561 tggacaggtt gcatgagttg gggtgccgtc agtgtagctg tttttggttt ctgagcttaa
     1621 atatcgaata atagctcctc aacctaatga ccagttaggc tttggaagcc ttttgtaaat
     1681 tgagatgtct ggaagtccag gatgacaccg aacagtgacc actaaccttc cctctggctg
     1741 ccgctgttga gagatgaagt ccaggtctgt tgtcagtgct cgctggggag cctctttatg
     1801 agcaaaaagt cccatgtttt agaattttgt atgaagatac tgtcatgagt gtttctaggg
     1861 cagtgcccag gggtgcgtgg cacctgctta accgtgcttc tctcagccac gtgcatagca
     1921 tttctgtata tttacacact gctgagctgt gtttattttt taactttgtt atgttttcgt
     1981 gctttctcat caaaccaatc cctgagtggc catgaatgga ggcacctccc ttcatcagaa
     2041 gtgtcagctc aaaccaagag gctcattctt ctccgtagct ttaagagaaa ggccccgtga
     2101 gtcccatggg gtcttcccat ttcagtttag aagcactccc cgggcagtca ccgttagtcc
     2161 ccctttcctc ccaggtgaga agaaagtgct tggtgtgcca tctgctggac aaaggaagaa
     2221 cagccctttt tttgcccctg tccctaaggg cagtttctgt tttcattttc acttgagcca
     2281 tggcagaaga ccagcgggtg tgcagtttgc agatcctacc tcacctatga tgcccaattc
     2341 catcctcact gtgtcccacg ttgccctctc tgtgttgggg actggggaga gtctgtgggc
     2401 tatgatactg gggtggacag gagttccatg ggctcctctc ccaccctcct ttccccagtc
     2461 catgactcgt cagccattcc cagtcactta gccaatgctt ggacatctgt gagcagcaaa
     2521 gacctgggcc cagggacacc tgcatgactc ccacatgaaa gcctctgagg cttctgttgc
     2581 gagggccttg gcaaaggcgg aaagagctgt gaacaaccat gggcatgaag atttctgtta
     2641 gcagatggca ggtactggtt agtgctttgg atacatcagt agctaggtct caaacgttgg
     2701 acattcccag tttctggtag gcatgagtat caccagagtg ttgcagaaat ctttcccaga
     2761 gggagtggtg gatgaagtgt gctcattctc atatgcaccc caccagccca cccccagttg
     2821 caatggagaa tactggtcat aggtcctaaa taattgctaa aatctggact atatttttag
     2881 ctttgagttt tcttgtcacc aaagcagtaa ggaagaggtg atgatctctt tgtataggtc
     2941 atacatcttc cctggtttga ggttacagtg agctatgatt gcaccactgc actctactct
     3001 gggtgacaga atgagacccc atctctaaaa aacaaaatta cccccttctg gggaaacagg
     3061 ttagatccta aagaaaatgt tcatgtgcat ccattcatag aggggacact gaatggttca
     3121 gtgggtgaca tcttcaagcg cagcaggctt tgaatgataa ctgattaagg cctccctcag
     3181 gagatggtga gatggttatg ataaggcaca tttcaagaaa gaggctctgg ggctaagtaa
     3241 ggcaaatggt ctataactgt ggttctttga agtctggctt aatccaggga tgacacccag
     3301 actgtctagg aagggctgag ctgcgtgccc tttaagtgat cacctcttag tataatttca
     3361 ctgagctgga ggtgagtgta agaagttcct ggttatagaa gaagttataa tccttggcat
     3421 ggcctgaagt aggcagtcca cactgatatg aaatgtgctg tgtatacctg gagaatgaaa
     3481 atgcccatct aagactggcc caagagctgg gcagccttcc tccatgggaa cctggcaagg
     3541 caatgggaag tggacatggg aacacctgaa ctttctggat gctatgaaac ctcaagggaa
     3601 caaattatgt ggcagagagg gataatctgt tcttcccatc tgagaaaaga ctgcagcaaa
     3661 gataaactat atgttgagat cattttattt gctacatcgg gcatcattct aaaaaccatt
     3721 ctttgcctga atctatataa atgacagttg aaagcagtaa aagtgggact gtttcactgg
     3781 agtcagccac actagtggtt ctcaaatctt ggtgaaccct gagagctacc caaggacttg
     3841 tttgcaatgc agaatcacag cccccagaga ctgacttgtg gggcccagct ggttctgatt
     3901 cggtggccag agaaaccgca tgtgtgcact cgggccacac atacagcctg gactggctta
     3961 tgtcaggccc atcctggttg tcaccatgag gacaatataa tgtcacttcc agtacttcgt
     4021 gttatttcct tctcttttag tatgagaagt ggccaagtgg tcaatagctt tcatctttgt
     4081 gtaactgaat cttgtgcttc atttccttct gggcattttt cattgttgat gaaataaact
     4141 ttgttcaatt tgt
//
