LOCUS       NM_001362796            2416 bp    mRNA    linear   PRI 14-FEB-2024
DEFINITION  Homo sapiens transmembrane protein 271 (TMEM271), mRNA.
ACCESSION   NM_001362796
VERSION     NM_001362796.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC116565.4.
            
            On Aug 31, 2019 this sequence version replaced NM_001362796.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000610212.3/ ENSP00000493161.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2416              AC116565.4         60665-63080         c
FEATURES             Location/Qualifiers
     source          1..2416
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p16.3"
     gene            1..2416
                     /gene="TMEM271"
                     /note="transmembrane protein 271"
                     /db_xref="GeneID:112441426"
                     /db_xref="HGNC:HGNC:53639"
     exon            1..2416
                     /gene="TMEM271"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..1391
                     /gene="TMEM271"
                     /codon_start=1
                     /product="transmembrane protein 271"
                     /protein_id="NP_001349725.1"
                     /db_xref="CCDS:CCDS93458.1"
                     /db_xref="GeneID:112441426"
                     /db_xref="HGNC:HGNC:53639"
                     /translation="MKWSVRGACAALSSCLLLACALSAAAVGLKCFSLGSELRGEPFR
                     LGAAAGAFYSGLLLAAGLSLLGAALLCCGPRDAPLAGSEPGPGLGVPAAPAGAPEATP
                     GESGAAAGAPGPVSSQNLLLLGVLVFMLGVLSAFAGAVIDGDTVSLVERKYSHYCLPP
                     RAPGSSPGSAPGSTPGSAPGSAPGSAPGSAPGAPRARSTLDSATSAKCRQLKDYQRGL
                     VLSTVFNSLECLLGLLSLLLVKNYKSSQARRGRRGRRRGGRALARPRGGSGLRAQPPA
                     SRARRGRRGRRGRRLQQRPSEASILSPEESDLAAPGDCAGFAAHHAVSYINVGVLHAL
                     DEAGAEVRCGGHPSVELPGYAPSDPDLNASYPYCCRPPCETPRPWETHRAC"
     regulatory      1671..1676
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM271"
                     /note="hexamer: AATAAA"
     polyA_site      1692
                     /gene="TMEM271"
                     /note="major polyA site"
     regulatory      1924..1929
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM271"
                     /note="hexamer: CATAAA"
     polyA_site      1966
                     /gene="TMEM271"
     regulatory      2394..2399
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM271"
                     /note="hexamer: AATATA"
     polyA_site      2416
                     /gene="TMEM271"
                     /note="major polyA site"
ORIGIN      
        1 ctctgcgccg catcggttcc cggcgcgggg tcgcggcggc ggcggcggcg gcggcggcgg
       61 cgggaggcgg aggatgcggg ctccggcggc ggcggcgcgg gcccgggagg acgcgggagg
      121 atgaggagga ggccggcggt ccggccgcgc ggcgccggga ggaggcgcag gcggcggggg
      181 cggcggcggg cggcggcggg cgcgcggggt gcgggccggc tcgggcgcgg aggatgaagt
      241 ggagcgtccg cggggcctgc gccgcgctct cctcctgcct cctgctcgcc tgcgcgctca
      301 gcgccgccgc cgtcggcctc aagtgcttct cgttgggctc ggagctgcgc ggggagccgt
      361 tccgcctggg ggccgccgcc ggcgccttct actccgggct gctgctggcc gccggcctct
      421 cactgctcgg cgccgccctg ctctgctgcg gaccccggga cgcgcccctc gcggggtcgg
      481 aaccgggccc gggtttgggg gtccccgcgg cgccggcagg cgctcccgag gccacgccgg
      541 gcgagtcggg ggccgcggcc ggggccccgg ggccggtgag cagccagaac ctgcttctgc
      601 tcggcgtcct ggtcttcatg ctcggggtcc tcagcgcatt cgcgggcgcc gtgatcgacg
      661 gcgacaccgt gtccctggtg gagcgcaagt actcgcacta ctgcctgccc ccgcgggcgc
      721 caggttcgag ccccggctcg gccccgggct caacccccgg ctcggccccg ggctcggccc
      781 ccggctcggc gccgggctcg gcccccggcg ccccgcgcgc tcgcagcacc ctggacagcg
      841 ccacgtccgc caagtgccgc cagctgaagg actaccagcg cggcctggtg ctctccaccg
      901 tcttcaactc gcttgagtgc ctgctgggcc tgctcagcct cctgctcgtc aagaactaca
      961 agtcgtcgca ggcccggcgc ggtcggcgcg gcaggcggag gggaggccgg gccctggcgc
     1021 ggccccgcgg cggctccggg ctccgcgcgc agccgcccgc ctctcgggcg cgccggggcc
     1081 ggcggggccg gcgggggcgg cggctgcagc agcggccgag cgaggcctcc atcctgtccc
     1141 cggaggagtc ggacctggcc gcccccgggg actgcgcggg cttcgcggcg caccacgcgg
     1201 tctcctacat caacgtaggc gtcctccacg cgctggacga ggcgggcgcg gaggtgcgct
     1261 gcggggggca cccgtcggtg gagctgccgg ggtacgcgcc ctcggacccc gacctcaacg
     1321 cctcctaccc ctactgctgc cggccgccct gcgagacgcc gcggccctgg gagacccatc
     1381 gggcctgctg atcccgcggg ccggaccccc atcccgcgga ccgcgcttgc gttccaccca
     1441 ccccgccccg ctcaggaccc ccgcggcaag ggaggacggg cagcggggcg gggtccaggg
     1501 ccaggcctca ggggcgccgc ctcttccacg tggctttgca gcctccggcc tggccccctc
     1561 tgcgggctcc gtgaccacag gagggggccc ctgatgtgac catttctgta tctgggaggt
     1621 ttctcttctt atttgtgtcg ttcatatctg gattccattt tcaagtttac aataaatgtt
     1681 tgggcttggc tagcccgact gcacttttct tggcaagtcc aaaccctggg gctgctctgc
     1741 ctggtggtcc gaggcgaggg ggacagagcg agcgccccag gacggcgact tcccacggag
     1801 gaagagcaga cagagacgca gagcagctgg taattcagaa agaagaagtg agaacaccca
     1861 acagcaacac tttgtacacg gatgtgcctg cttttgttga tactttctta ctgtaaagct
     1921 ctccataaat agtgaaaatg tttggtaaat ttattgcaat ttaaaattgg tgagttcctt
     1981 tattaaatta attgctatgt tattggagaa tattcatcaa attggaatta gaggatgtct
     2041 acgcacaagt cagtgtgggg ggaaatggtt tcatttggtc ggacaaatgt tgagtttgaa
     2101 cagttgtatt ctgctagcta gttgactgaa tccagcctct ttctaaagct aactttctgt
     2161 gtgtgtagag accctgatgc cacatcccat acatttcttt tttcttttct tttttttttt
     2221 ttggaaactg gttgtgtggt ttcgactgca aagcagatct tatttttgat taatacatat
     2281 gaacaattta atcctatttc ggaaaatcag tcatagtttt tctggcatag ataattttcc
     2341 tgttgattat ttcattaatc tggtaatttt gagtatgata gcatttcatt tcaaatatac
     2401 cccgtaatcg ccttaa
//
