LOCUS       NM_001354602            3404 bp    mRNA    linear   PRI 26-MAY-2023
DEFINITION  Homo sapiens transmembrane protein 269 (TMEM269), mRNA.
ACCESSION   NM_001354602
VERSION     NM_001354602.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC098484.2.
            
            On Nov 10, 2020 this sequence version replaced NM_001354602.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803617.362487.1,
                                           SRR5189667.6181.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000637012.2/
                                                ENSP00000490213.1
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                AC098484.2         132969-133060
            93-231              AC098484.2         137774-137912
            232-329             AC098484.2         140783-140880
            330-473             AC098484.2         141579-141722
            474-674             AC098484.2         142391-142591
            675-3404            AC098484.2         146076-148805
FEATURES             Location/Qualifiers
     source          1..3404
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.2"
     gene            1..3404
                     /gene="TMEM269"
                     /note="transmembrane protein 269"
                     /db_xref="GeneID:100129924"
                     /db_xref="HGNC:HGNC:52381"
     exon            1..92
                     /gene="TMEM269"
                     /inference="alignment:Splign:2.1.0"
     exon            93..231
                     /gene="TMEM269"
                     /inference="alignment:Splign:2.1.0"
     CDS             191..802
                     /gene="TMEM269"
                     /codon_start=1
                     /product="transmembrane protein 269"
                     /protein_id="NP_001341531.2"
                     /db_xref="CCDS:CCDS90932.1"
                     /db_xref="GeneID:100129924"
                     /db_xref="HGNC:HGNC:52381"
                     /translation="MVLGLFSIIFSFSRKCHYASRMLLVSFLLDMAVRAMTSHINICS
                     KLGAELNDFAVFTTFGLASALLLGVDGLLSGILAIIYVSAASFHLCFYSPGVPSTYKG
                     LPCPYASCILASTSLLTKGNRFILCCMASLMILFMMDQSYYPYDKILESENWKKLVYI
                     GGVIMLFFSPLSLSAFYCLMWSLSYIFFPDALWGKAACLSPQH"
     exon            232..329
                     /gene="TMEM269"
                     /inference="alignment:Splign:2.1.0"
     exon            330..473
                     /gene="TMEM269"
                     /inference="alignment:Splign:2.1.0"
     exon            474..674
                     /gene="TMEM269"
                     /inference="alignment:Splign:2.1.0"
     exon            675..3404
                     /gene="TMEM269"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3219..3224
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM269"
                     /note="hexamer: AATAAA"
     polyA_site      3241
                     /gene="TMEM269"
                     /note="major polyA site"
     regulatory      3373..3378
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM269"
                     /note="hexamer: AATAAA"
     polyA_site      3404
                     /gene="TMEM269"
                     /note="major polyA site"
ORIGIN      
        1 agggctggcc ccctccaccg cacaggaaac ggggcaggag ggcggacccc catctcatgt
       61 aggaatgccg tgtccccagg gtgagccctc aggtaagggt accagtttct tcctgagcca
      121 tgaccagagc cattcccaga taaatgaggt ttcctggaag gatgttacca gtgccttatc
      181 tctggccaac atggtgctgg ggctcttctc catcatcttc agcttcagca ggaaatgcca
      241 ctatgcctcc cggatgctcc tggtcagctt cctgttagac atggcagtca gggcaatgac
      301 cagccacatc aacatatgct ccaaattggg agccgagctg aatgactttg ccgtcttcac
      361 caccttcggc ttggcctccg ctctgctcct aggcgtggat ggacttctga gtgggatcct
      421 ggccatcatc tatgtgtcag ctgcttcttt ccacttgtgc ttttattcac ctggagtccc
      481 ctccacatac aagggtctac cctgccccta tgcttcctgc atcttggctt ccacctccct
      541 tctgaccaaa ggcaacaggt tcatcctctg ctgcatggcc tcactcatga ttctcttcat
      601 gatggaccag agctactatc catatgacaa aatcctggag tctgagaact ggaaaaaatt
      661 ggtttatata ggaggtgtca tcatgctgtt tttctcccca ttgtctctgt ctgcttttta
      721 ctgcctgatg tggtcgctct cgtacatctt ctttccagat gctctgtggg gcaaggcagc
      781 ctgtctttcg ccacagcact gaggaagcta agcagctcta ccagctcctg ccggcctctg
      841 tggggtttgt gtcagcatat tgggtcaagc ctgcactaaa gctttgtatg tacctgtgtt
      901 gccatatact agatatatgg tatgtctgtt gccatgaagt tagaaaccca aagcagggtc
      961 agtgaacttc acttctttgt ctttattcag ggttctgact cccttgcgga caatacttgt
     1021 ttatgtcatg tagagcagaa tatccccccg cctcaagctc aatgtgggct gggtttgggt
     1081 tccagctcca ttaccagccg ggtgactgtg tgctactaag gtccatccct tggaaaggag
     1141 tgagagcctt cagaactggt attggcctca gcctcagccc tgcctggtgg ggcttcctga
     1201 agcatttctt actcttgcag actctggctc tgagagtaga gccaatcaca ggactctctt
     1261 gttgcctagt ttgaatgtgt gtaggatttt gtaacttcaa cattctgggt tttttttttt
     1321 tttttttttt tttttttgag aaggagtctc gctctttcac ccaggctgga gtgcagtgga
     1381 gcgatctcgg ctcactgcag gctccgcccc ccgggattca cgccattctc ctgcctcagc
     1441 ctcccgcgta gctgggacta caggctcccg ccacctcgcc cggctaattt tttgtatttt
     1501 tagtagagac gggggtttca ccgtgttagc caggatggtc tcgatctcct gacctcgtga
     1561 tccgcccgcc tcggcctccc aaagtgctgg gattacaagc gtgagccacc gcgcccggcc
     1621 tacattctgt attttaatag ttcaaagctg ccgccttttg ctttgtttag cagttagata
     1681 cattggtgac acagggcatc atctggcttg caggatctcg tgtggatttt ctttcctacg
     1741 ctggaaacta ctaaactcta gctattcaga tgccacttca tattctaaaa tccaaatcaa
     1801 atagaaataa acagtactgt atggcaaagg tgtacctcac cgagaactca ggtccactga
     1861 gcccccagcg tagatagaca ttccacctcc cagatggtgg aaaaaaggat tgatggctgg
     1921 ttctgctcca ccctcagaga ctgtgccaga acaccttcta ccctggatat aactttttta
     1981 agtttccaga acaatgtatg tggtaaatat acatctattc tcaaattaga tgtttaaaaa
     2041 taaaaaccca aagtaagatt tgactgtaac agaatagacg gtgccttcct gttaaatcat
     2101 tcatatgttc ctagttagat ggatttgcct gtgtcccagg actttatatc tccttcagtt
     2161 taagttttgt atttttgcta tctgccatag tgcctgacac tcagaaatgt tccctttgta
     2221 tatgaattga tttagttgtg gattctagta agttacatac aaggtttcta taatgtggta
     2281 agaattttac aaatatacac gagcttagac atttcaatac aatgtccttc aatgctgtac
     2341 atccatttca atgtgatgct ccccttaatc aaagcatttt aggaactcca atctgaaaat
     2401 ggtcttcaca taaattctta aggaccaagc agctggaaca acaccaccac caccaaaagc
     2461 gaaaaacagg ttttattctg aactaaattt tttccaaaaa cctaacattt gagattagcc
     2521 aattatgtcg tattcttaaa tcaaattagg tatcatattt ggactcaaat gccttgtggc
     2581 tgtttctaaa atttgaaact atgttgaaag gaaaaagatg caattctgaa agagaatttc
     2641 catgtccatt ttaagtgaca gcagcagaga gaaatataca gacccccagg aggacagctt
     2701 tgaaaagtaa aatgcccatt tggatgtgta aattatcgct tgattgtaat ggcaataatt
     2761 catacttaat tgcctccagt tttttttgta ggttaatgac actaggatag ttataggtca
     2821 gctgacagcc ggttaacaga gggatctatg cttccttgca cctctctgag agtatggtta
     2881 tacttctata cgggcttgag ggtctcagat actaaggcta ctcattcaat gccttcactt
     2941 cctcagacag tggttttcta aaatagaatg tctcttcttg ggcttcctct taggaacaag
     3001 ggagaaggcc aagactttaa aatctgcact tctcaaatgc atacatgaag ccagtggggt
     3061 ttaggcagtt ctctttgtcc taagcttgag agagagtgta gatttccctc ctggtcaact
     3121 tctagtccct tcttcctaac ctgaagtcct acttctgtgt ctgataagcg gaatcaagtg
     3181 actgagaatt ctgctactct tttagccctg tgaccttgaa taaaacgttt aatctctcta
     3241 agcctatttt cctatctgta aaatggagga tttacttcct ttcagggttg ttttgtggat
     3301 tgaacaaccg tgatgtttta tgtggatgaa tgtaaaacac ctagaataat gaatggcacg
     3361 taaaatatgt taaataaatg ttagatggct ttctgtcccc tcta
//
