LOCUS       NM_001256829            1649 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens transmembrane protein 265 (TMEM265), mRNA.
ACCESSION   NM_001256829
VERSION     NM_001256829.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1649)
  AUTHORS   Wistow,G., Bernstein,S.L., Wyatt,M.K., Fariss,R.N., Behal,A.,
            Touchman,J.W., Bouffard,G., Smith,D. and Peterson,K.
  TITLE     Expressed sequence tag analysis of human RPE/choroid for the
            NEIBank Project: over 6000 non-redundant transcripts, novel genes
            and splice variants
  JOURNAL   Mol Vis 8, 205-220 (2002)
   PUBMED   12107410
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC073882.1, AC106886.3 and CA432634.1.
            
            On May 17, 2019 this sequence version replaced NM_001256829.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7346977.322550.1,
                                           ERR279845.5453.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000615541.3/ ENSP00000477871.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-734               BC073882.1         262-995
            735-1481            AC106886.3         123215-123961
            1482-1649           CA432634.1         17-184              c
FEATURES             Location/Qualifiers
     source          1..1649
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p11.2"
     gene            1..1649
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
                     /note="transmembrane protein 265"
                     /db_xref="GeneID:100862671"
                     /db_xref="HGNC:HGNC:51241"
     exon            1..66
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
                     /inference="alignment:Splign:2.1.0"
     exon            67..234
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..396
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
                     /codon_start=1
                     /product="transmembrane protein 265"
                     /protein_id="NP_001243758.1"
                     /db_xref="CCDS:CCDS73870.1"
                     /db_xref="GeneID:100862671"
                     /db_xref="HGNC:HGNC:51241"
                     /translation="MEDEEKAVEILGNTEAAHPPSPIRCCWLRLRCLAATSIICGCSC
                     LGVMALVFAIKAEERHKAGRSEEAVRWGARARKLILASFAVWLAVLILGPLLLWLLSY
                     AIAQAE"
     exon            235..1649
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      709..714
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
                     /note="hexamer: AATAAA"
     polyA_site      734
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
                     /note="major polyA site"
     regulatory      1590..1595
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
                     /note="hexamer: TATAAA"
     polyA_site      1622
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
     polyA_site      1649
                     /gene="TMEM265"
                     /gene_synonym="IFITMD8"
ORIGIN      
        1 ccacccaagc caaaccaaag ctgaggcagg agccgaaact cagagtcctt caaggcctat
       61 agccaggtga tggaggacga ggagaaggca gtggagatct tgggcaacac ggaagctgct
      121 catcctccat cccccatccg ctgctgctgg ctccgcctcc gctgcttggc agctactagc
      181 attatctgtg gctgctcttg cctgggagtc atggctctgg tgtttgccat caaggcggaa
      241 gagcggcata aagcaggccg gtccgaggag gcagtgcgct ggggggcccg ggcccggaaa
      301 ctcatcctgg ccagctttgc tgtctggctt gctgtcctca ttctgggtcc cctgctgctg
      361 tggttgctct cctacgccat cgctcaggct gagtgaccct ggatggcctc tgctgagagc
      421 cagccgagac ctcctggatc ctgcaatgcg gcattgctaa ggtcctgtga cagcagtggt
      481 tggaaggatc ctggttggaa ggatggggac tctctcaagg ggctttggaa gagctcttct
      541 agccctttat aaaaggaggg cagcagctga gactgatgag aggagggcag cctgctctgt
      601 tctttcaggg ccccccaccc ccatctcccc taccctagcc caccctaggg cctctaccca
      661 gcgggagggg ttgaagacca ggcctggttt tattagaatt cattttgtaa taaaagcctt
      721 ttttagtggt gaaatactcc tgtctaattg ttctcctcct gctttccctt gggcccttgg
      781 tgagagccag actggacatc tgactgatag cagaagccag catccacctc atccaggagc
      841 tccaagagaa ggaaacaatt tttattttct tcttctggaa gtttcccttc ttggaaagac
      901 cccagcttct cccttgtacg tccacagaga ctctgaggcc aagagtagta gcagctgcta
      961 ctatttatta cttactatat tccaggctgt gttctaagca ctttatattt cttaacttcc
     1021 tccagttttc agtcactcag tagatgtctg tactatcata tccatcatat gaatatatca
     1081 catatgatag gtaccaacta tctgagtgaa aactggaaga aatgttctaa aatgacagtg
     1141 ttctcgtttt atacttgaag aaacaaacag atttgcacaa ggtcctcagc tactaaatgg
     1201 tagagctgag actgaaccca gacagtttgg ttccagagct gagagaggag tgaaagagtt
     1261 gggtaacagc aacaaccatc ctgtacatgg agatttgagt gattaaaatg gattttcata
     1321 tcttttatct tggacctcat aatatttcaa atttttttta aaattatgaa gtatatcata
     1381 catataggaa aatacccaaa acaagtatac agttcattaa cacaaagcaa acgtgaataa
     1441 ccacattcag taaagaaatt ggaacactgt caacacttca aagcctcctt tatactcctc
     1501 ccaatcactg ctacttcctt tcttcccaca ggtaaccacc attctgactt ctagcagtgt
     1561 catttaattt tgtctgcatt tgaactttat ataaatggaa tcatgtattc ttttcatgtt
     1621 aacattgtga gattcgtcaa tatttggaa
//
