LOCUS       XM_017014571            7972 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transmembrane protein 245 (TMEM245),
            transcript variant X3, mRNA.
ACCESSION   XM_017014571
VERSION     XM_017014571.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017014571.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7972
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..7972
                     /gene="TMEM245"
                     /gene_synonym="C9orf5; CG-2; CG2"
                     /note="transmembrane protein 245; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 59 ESTs, 3280 long SRA reads, 2 Proteins, and 98%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 156 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:23731"
                     /db_xref="HGNC:HGNC:1363"
                     /db_xref="MIM:620252"
     CDS             35..2647
                     /gene="TMEM245"
                     /gene_synonym="C9orf5; CG-2; CG2"
                     /codon_start=1
                     /product="transmembrane protein 245 isoform X3"
                     /protein_id="XP_016870060.1"
                     /db_xref="GeneID:23731"
                     /db_xref="HGNC:HGNC:1363"
                     /db_xref="MIM:620252"
                     /translation="MADGGGPKDAPSLRSSPGPAPRVPRAVGPSGGGGETPRTAALAL
                     RFDKPIKQAFYNTGAVLFVCLCCGAAVLVYFILEAFLRPLLWAVLCGTFLHPFKSSLT
                     RLGRHWLQRLHRAHTPIVLAALLLPLCFVDYGVEALGEQALRRRRLLLLLGAGGPLLY
                     GLYCLGSYLGVQVLLVHAATLICRGLDYFSSLWIWTLVVGYVLTVSFKWNASTERYLR
                     AVSIPVWIILLFHLASLAGSWRIPVFLVIVFLMSVGTLYEKQNGKESSGAELPGQVIS
                     MAASTLANLAISITGYESSSEDQPSTQPAAVDRGESAPTLSTSPSPSSPSPTSPSPTL
                     GRRRPEIGTFLRKKKTSDIYFVSLVWAIVVMQIWLNLWIVQLLPVPIAVWILKKLVIH
                     FGVVDFLEKRYHVWWGIIESFLKERQGALAPWPIVGLGKFLLKVDSKMIIWLEKMLDK
                     IISIFIIFLLVIGTLLLALLLTAKVHQESVHMIEVTSNLINETLANHPEWANWLPEAQ
                     VVQRALNSAANNVYQYGREWITHKLHKILGDKVNNTAVIEKQVLELWDRLYHSWFVKN
                     VTHSGRHKGQKLHVSRQNSWLGDILDWQDIVSFVHENIETFLSILESLWIVMSRNVSL
                     LFTTVTTLLTILFYSGTALLNFVLSLIIFLTTLFYLLSSSDEYYKPVKWVISLTPLSQ
                     PGPSSNIIGQSVEEAIRGVFDASLKMAGFYGLYTWLTHTMFGINIVFIPSALAAILGA
                     VPFLGTYWAAVPAVLDLWLTQGLGCKAILLLIFHLLPTYFVDTAIYSDISGGGHPYLT
                     GLAVAGGAYYLGLEGAIIGPILLCILVVASNIYSAMLVSPTNSVPTPNQTPWPAQPQR
                     TFRDISEDLKSSVG"
ORIGIN      
        1 accgcccctc gggggcggct gtggcggagg aacgatggcc gacggcggcg gccctaagga
       61 cgcgccaagc ctgcggagct ctcccgggcc ggcgccgcgg gtcccgcgcg cggtcgggcc
      121 gagtggcggt ggcggggaga ccccgcggac cgcggcgctg gcgctgcgct tcgacaagcc
      181 cattaagcag gccttctaca acaccggggc cgtgctgttc gtgtgcctgt gctgcggcgc
      241 cgcggtgctg gtctacttca tcctggaggc cttcctgcgg ccgctgctct gggccgtgct
      301 atgcggcact tttctgcacc ccttcaagag ctcgctgacg cgcctgggcc gccactggct
      361 gcagcgcctg caccgcgcgc acacgcccat cgtcctggcc gcgctgctcc tgccgctctg
      421 cttcgtcgac tacggcgtcg aggccctggg cgagcaggcg ctgcgccgcc gccgcctgct
      481 cctgctgctc ggcgccggcg gcccgctcct gtacggcctc tactgcctcg gcagctactt
      541 gggcgtgcag gtgctgctgg tgcacgctgc cacgctcatc tgccgcgggc tggactactt
      601 cagcagcctg tggatctgga cgttggtggt tggctatgtg ttgactgttt cattcaagtg
      661 gaatgcaagc actgaacgct acttgagagc agtttcaatt cctgtctgga ttatattgct
      721 ttttcattta gcatccctgg ctggctcatg gagaattcca gtattcctgg ttattgtttt
      781 cctgatgtct gtgggtaccc tctatgaaaa acagaatgga aaagagtctt ctggggcaga
      841 gttaccaggg caggttatct ccatggcagc ttctactctg gcaaacttgg ccatctctat
      901 cacagggtat gaatcaagca gtgaagacca gccctccact cagcctgcag cagtggacag
      961 gggagaatcc gctccaacgt tgtccacctc cccttcaccc tcctcccctt cacccacttc
     1021 cccttcacct actctgggca gacgaaggcc tgaaatagga acgtttctta gaaagaagaa
     1081 aactagtgac atctactttg tgtctctagt ttgggccatt gtcgtcatgc agatctggtt
     1141 gaacctgtgg attgtgcagt tgctgccagt gccgattgca gtctggatac tcaaaaagct
     1201 tgtcattcac tttggagttg tggatttcct agagaaacgc taccatgtgt ggtggggcat
     1261 tatagaaagc ttcctgaagg agcggcaggg agctctcgcg ccttggccca ttgtcgggct
     1321 tggaaaattc ttgttaaaag ttgatagcaa gatgatcatc tggttggaga agatgttaga
     1381 taaaataatt agcattttca tcatattttt gttagtgata ggaactcttc ttttagccct
     1441 actcctgact gcaaaggtac atcaagagag tgtacacatg attgaagtca caagtaattt
     1501 gattaatgaa actctagcaa atcaccctga gtgggcaaat tggcttcctg aggctcaggt
     1561 agtccaaaga gccctgaatt ctgcggctaa caacgtgtat cagtatggac gagaatggat
     1621 aactcacaag ctccataaaa ttctaggaga taaggtgaac aatactgctg taattgaaaa
     1681 gcaagtacta gaactttggg acagactgta tcactcttgg tttgtaaaga atgtaacaca
     1741 ctctggaagg cacaaaggac agaagttgca tgtcagtcgt cagaatagct ggctgggaga
     1801 cattctggac tggcaggata ttgtttcctt tgttcacgag aacattgaga catttctttc
     1861 gatcttggag tctctgtgga tcgttatgag ccggaatgtg agcctgctgt tcaccactgt
     1921 cactacactc ttgaccatcc tcttctacag cgggacagcc cttctcaatt ttgtactctc
     1981 tctgataatt ttcctgacca cactatttta tctattaagt tccagtgatg agtactacaa
     2041 gccagtgaag tgggtgataa gcctgactcc actatctcag ccaggtcctt cttctaatat
     2101 tattggccag tctgtggaag aagctatcag aggggtgttt gatgcttccc tcaaaatggc
     2161 tggcttctat ggattgtata cctggctgac tcatactatg tttggcatca atattgtctt
     2221 cataccatca gcattagcag caatccttgg agcagtgcca ttcctgggga catactgggc
     2281 agcagtacct gcagttcttg acctgtggct gacacaaggg ttaggatgca aggccatttt
     2341 actgttgatt tttcatctct tgccaacata ctttgtagat actgcaatct actctgacat
     2401 atcaggaggt ggccatcctt acctgacagg cttggcagtg gccggtggag catactacct
     2461 aggcctggaa ggagcaatca tcggtcctat tcttctctgc atacttgtgg ttgcttccaa
     2521 tatctatagt gccatgctag tgagtcccac gaattcagtt cccacgccaa accagacccc
     2581 atggcctgct cagcctcagc ggactttccg tgacatttct gaagatctga aatcttcagt
     2641 aggttgatgt ggtttcctct gcagtgattt ttctaggaag ttcaaatttg acagcgagtt
     2701 cagctcagct gtggccctct gcccttccag ctgtgcctag caagcaaaac ccaggaaaga
     2761 agcagaagcc tcctggcctt acatacagaa tgcctggaca agagagaact tgctgcgggc
     2821 tgctttgtat tttaaaacac agcttgagag ttcagagttg gtggtttgct cacttaactg
     2881 ttgttaagat ggcttgaaaa gtttcatttt atacactggt accctggctt gaaatttttc
     2941 cactttggtt atctatgtta ctatattata tatttataaa gttattttaa gaactctaaa
     3001 ctacctgctg ttaaaagaat agatggtgta attttttcct ggtttaagaa atgtattgtt
     3061 aaacttttct aagacagtca cttttcaagg aagagggctt tcacttttga gtgtgtagtt
     3121 gagtgagcag gaaaaatgaa tcttctaccc ttctcccaca atgtattata cgctctttaa
     3181 gaaataataa atcataagta taagggtggg gtggcttatt tgatgttcag ttttatatta
     3241 taaccctggg agatacaaag actgaagctc ttcctcctct tccttttctc ttcacgcttc
     3301 tttacactat tgccaaatta taaaacttgg ctgaccacgt tgaagtgaaa tacttattaa
     3361 gctgctatga atggtaacag tatgataaaa ttcatgctgt tattaggttt tctccttcca
     3421 ggtggttgaa gtgaaaaatc tcaggtgtag caatactctg atttgttaaa tgtatccgtt
     3481 tcattatttg gaactctgcc aataagttag ttttcagcag aattttgtat ttatgtagta
     3541 ttttcccatc tcttagcaca gtgccttgca catgactcta aatgaatgct tgttgaattg
     3601 aattgcaact ttaaaaatat ctcagatatc acaataacca gcatagtgct ttacatttta
     3661 caaagtcctt ttgcacatac tatttcacaa gtacatcaca tcagctttca tatagcttta
     3721 tattatttta catcagtttt acactgatgg agaagctaag gttcagaaaa gtgaccaact
     3781 caaagtcgta aagtgtagta ggatttggcc tcagatcttt gactccgttg tgtgcagatt
     3841 ctgctgtatt agtgttcctt ctaaatattg tatgcagttt tcccagtgtt acgagattgg
     3901 tgttgctatc catttgttgt gaatgaagac ttgtcctata gtacatgaca gggctgagag
     3961 tggactgtag ttcttagctg aaccctttct actgtttaaa acaatcatca ggcctatcct
     4021 ctgctcccag gggaatgtgg gagagaaaag ggttcttggc caggctgtag gtggtggctc
     4081 acatctgtaa tcccagcact ttggaaggct gaggtgggtg gattgcttga gcccagggat
     4141 ttgagatcag cctaggcaac atggcaaaac cccatctcta caaaaaaaaa aaaaaaaaaa
     4201 aaaaaattag ctgggcacgg tggtgtggct atagtctgag ctactcagga ggctgatgta
     4261 tgaggatcac ctgagtccag gaggtcgagg ctgcagtgag ccaagatggc gccactgcac
     4321 tccagcctgg gtgagagagt gagacactgt cccaaggaaa aaaaaaagtg ttggggggta
     4381 gttcttaagc gttgaagatt tcctttttgg aaagtattta aaggtagaaa tattaataat
     4441 ttttcctaaa acatctccct aagaagtcac tgataattat aattagttta aatttattct
     4501 tacactactt aagaaaaatt tcatttagaa aaggctacca tgagatcttt tgactatatg
     4561 gagtagactg catacagatc tctttatttc tattatgaat attttagcga ttataatcag
     4621 ctattccact gagtattaga tttggtcact aagtaactca tgtttttctt tagtcaatca
     4681 ttcattcatt cactaaaaca tttgttgaga gttggctaaa ctctagattc tgtgccaggc
     4741 actgtacagg gtgatggaga tcactcataa gaaggcctct tgctcttagc cagatcatat
     4801 gtaatactaa atttaaattt tttgcattaa aaggctaaaa aatcatttgt ttttgttaat
     4861 tatatactgg ttgatttata gatgtaatta gcacatattc ataagagaca aatatataca
     4921 atgagttact atacatatac aaagtgattt tagctgtata aagtgatatt gcaaaaaact
     4981 acagctaatg tttcttgctg ggtaattatt agcataaata tcaggttctt agaggtcttt
     5041 aagagaatac tttagagcta ccaaaattag cagcagtgat gtaatatcac cctgaaatac
     5101 caggagcaga ggtgccccag agtgcttcac agctatgatc aggaaacttg acctgcccca
     5161 ttgctacagc aacggcataa ggactaggaa ggtccactag ctggggaggt cttggaaccc
     5221 tccgagccag aaagaagcat tccagcatga ttcctcagat gcaatgagga aggtttacag
     5281 aattttcaca gggcaacaga gatcaagtgg tatgaaaagg taggagtttt aagctcaagt
     5341 ctcaaagata acctaccttt acattctcag tcagaatttg acccagaaag aggaagtttc
     5401 ttcaggaaca gaccgtacgt tgatgaagta gaagtcattt cagtaaaaac ggagtacaga
     5461 acttggtcat aatatcttgc attttataga tttattaaag attagtttca agttcacatt
     5521 cgctattcag ttgtaaaccg aatggatggg aggggagaaa atacaagctc tccacacagg
     5581 tatgctcctc tcttttctga gagagaaggc atgggatttt cagcataaat tccatgttat
     5641 gtgagtgctg tttgagttct gaagttccta tcaatatctg ttcctgcaag tgatctctgt
     5701 aagaccacct tacatgctgg tcttagttat tgttaaaatt gcaaggtttc ttcacaccct
     5761 ctttgataag aagtgtttag ctggcagagc tttcccttga cttctgagtc tagtgtgggt
     5821 tggcccatga cagtgggaag aaatccaaca tgttacatgg agaccttgta tgtaaacaaa
     5881 ctctgtagcc tttgaaagtg gaactgcttt ttacagttaa agggctgcta aatggcttgc
     5941 agatgagatc ttctggctca ccttgatctt cacatgaacc cattgtgacc tatctggatt
     6001 tcctaggacc tgtagtttcc atttgggtta tattagtgcc tcaggaatgt gtcactactg
     6061 gtcaagcaat actcagaaat tcaggctgtg aggggttaga ttagaggaaa gtaatttagg
     6121 tgagctatcc agagctttca acctcagggt ttataggaaa aaaaaacaaa atacaaaaac
     6181 ccttaggact tctcatactc tagccctgac cttgcagtct cctctgaggg gcctcctaag
     6241 acccttaaaa taatattaca ataggacttt gagtgtgcat ttcacagtgg aaatagcctc
     6301 tggctagcat tacttccaaa tgctagttcc agctaaaaac aagtactttt tattagtttc
     6361 ttgtctttca acattctgcc atcaaaatat attcatttta ttaacttacc gattattggg
     6421 aacctgcaaa aaaaaaaaaa aaaaaaaaca cacatgctgt ctgcagccac tgtttggtta
     6481 tttttgatag tttaagagaa ttataaatca agttgttctg tctactagag tcagaaattc
     6541 tgtgctagaa tgggacttct aaaattaggt ggtcctgtca ctttctagag aaagacccaa
     6601 attcataggt ttaagtggct tgtctgacat acacatacag ccagttagta acagaattca
     6661 gaatagaata gagttctttt ttttctgtca gtccgttgtt ctacttctct ttccttttct
     6721 tcatggttga gcagcttttg gcaaaatgtg ttccatatag cagtagttcc aagagatgtt
     6781 aatagatgta agaaaaaaag tgtgtgtgtg ttgggggtgg gggattgcat ggtcaattaa
     6841 aatgaaggaa tgctgagttt gtttccttac tgtaggactt ctaagagttt tgaacatgct
     6901 attacacatt gtgaatttat aaaaggggac aaacactgtt tgaccttaga ctgcactccc
     6961 cttctttatt cctcagagca tctcaaagga ctacagggtc ctttgagaaa catggccctt
     7021 gatcaagttt acaactcttt gagaagacat ccctaatgga aatactgaat ggcagatcta
     7081 ttactgtggt accatgtagt gtgtaataaa tcttgaagtc cagaaagcaa gtatatttgc
     7141 tgtttagagc tatacttaag gtatagagat tcttttccac ctgtggtgtg taaaatcagt
     7201 attgtgttta attttgcagg tttttcaagg atcaactaat gtgcaaatac agtggtgata
     7261 tattgatatt acattttaat aatgcttttg tatggcactt tatagttttc agacaccttt
     7321 tgtaacagcc ctgtgagaca gacaatatta tccttattgt acagatgggg gggctctgga
     7381 ggctctgaaa agtttttggt gatattcccc taagtttata ccacaaaatg atggagccag
     7441 aatttagttg cagaacttct gactccaagt ccagagttct ttactagaca tctggtttct
     7501 tactagcttt ttgctagctt tttattttac agtgaaaagt atggaagcaa atcctgataa
     7561 ttttggctta ttatcaaata tcatttattt tttattgcag agacccagca gatgtaactc
     7621 tcattgtagc catcccaaag aaaacccttc tttgcccttt gcagtgccac ttatttaggt
     7681 aactgaagtg tatttccagt acaatttgat tttgaactaa gatttgatat agagttgtaa
     7741 ttgcttacat aactctttga aaatgtatca tccctgggtt ctcaggtgaa ggaggcaatt
     7801 caaaagtaaa aaagaatatt cgaatacaat aaataccctc tgttctcaca caaatgctgt
     7861 ttcttagcta acttgctttg acaacctact gatgtaactt ctttattaat gtgaaatatt
     7921 tatattttga aataaaatta ctagtgttga atgaatcatg tggtaaactt aa
//
