LOCUS       NM_001190764             695 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens transmembrane protein 238 (TMEM238), mRNA.
ACCESSION   NM_001190764 XM_498725 XM_938054 XR_248580
VERSION     NM_001190764.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC020922.9 and BC052596.1.
            
            On May 17, 2019 this sequence version replaced NM_001190764.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The genomic coordinates used for
            the transcript record were based on transcript alignments and
            orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052596.1, SRR1163658.208850.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA2142586
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000444469.4/ ENSP00000416154.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-73                AC020922.9         92503-92575         c
            74-695              BC052596.1         17-638
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.42"
     gene            1..695
                     /gene="TMEM238"
                     /note="transmembrane protein 238"
                     /db_xref="GeneID:388564"
                     /db_xref="HGNC:HGNC:40042"
     exon            1..571
                     /gene="TMEM238"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..564
                     /gene="TMEM238"
                     /codon_start=1
                     /product="transmembrane protein 238"
                     /protein_id="NP_001177693.1"
                     /db_xref="CCDS:CCDS54323.1"
                     /db_xref="GeneID:388564"
                     /db_xref="HGNC:HGNC:40042"
                     /translation="MAAAPAVCASQGSPPGAPSAPAAAPAPAAGLGRCRMALLLAVAL
                     DVAGMAALLTGVFAQLQVRGRDFGDLLIYSGALLVFLSLLGWILWYTGNIEISRQELE
                     RDYGLRPSALARLARKLSRRWSAPAAAGQRPAPGSRRARRAARAPPPPAAGSRRVRLQ
                     LATLEAGPGAAGAGSE"
     exon            572..695
                     /gene="TMEM238"
                     /inference="alignment:Splign:2.1.0"
     regulatory      674..679
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM238"
                     /note="hexamer: GATAAA"
     polyA_site      695
                     /gene="TMEM238"
                     /note="major polyA site"
ORIGIN      
        1 ctctctgggc gccagcggcg gcggtgcagg gccatggcgg cggcgccagc ggtgtgcgcc
       61 tcgcagggga gcccgccggg tgcaccgtcc gcgccggcgg ccgcgccagc acccgcggcc
      121 ggcctgggcc gctgccggat ggcgctgctg ctggccgtgg cgctggatgt ggcgggcatg
      181 gcggcgctgc tgaccggcgt gttcgcgcag ctgcaggtgc gcggccgcga cttcggggac
      241 ctgctcatct actcgggcgc gctgctggtg ttcctgagcc tgctgggctg gatcctctgg
      301 tacaccggca acatcgagat ctcgcgccag gagctggagc gcgactacgg cctgcggccc
      361 tcggcgctcg cccgcctggc gcgcaagctc tcccgccgct ggtcggcgcc cgccgccgcg
      421 ggccagcgcc ccgcgcccgg ctcccggaga gcgcgccgag ccgcccgcgc gcccccgccg
      481 cccgccgccg gctcccgccg cgtgcgcctg cagctcgcca cgctcgaggc cgggcccggg
      541 gcggcgggcg cgggcagcga gtgaggccca gacaacccct tggctccagc tgtcaggacc
      601 agactgagat gtgcagctgc ccctacatcc gtggccagac ggacgctccc tgtaccccct
      661 ccctcctcac ttggataaaa agcagatttg cctta
//
