LOCUS       NM_001164436            1881 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens transmembrane protein 212 (TMEM212), mRNA.
ACCESSION   NM_001164436 XM_002342383
VERSION     NM_001164436.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1881)
  AUTHORS   Brown,A.A., Jensen,J., Nikolova,Y.S., Djurovic,S., Agartz,I.,
            Server,A., Ferrell,R.E., Manuck,S.B., Mattingsdal,M., Melle,I.,
            Hariri,A.R., Frigessi,A. and Andreassen,O.A.
  TITLE     Genetic variants affecting the neural processing of human facial
            expressions: evidence using a genome-wide functional imaging
            approach
  JOURNAL   Transl Psychiatry 2 (7), e143 (2012)
   PUBMED   22828495
  REMARK    GeneRIF: The specialized function of this brain region suggests
            that TMEM212 could contribute to the innate architecture of face
            processing.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1881)
  AUTHORS   Turner,S.T., Bailey,K.R., Schwartz,G.L., Chapman,A.B., Chai,H.S.
            and Boerwinkle,E.
  TITLE     Genomic association analysis identifies multiple loci influencing
            antihypertensive response to an angiotensin II receptor blocker
  JOURNAL   Hypertension 59 (6), 1204-1211 (2012)
   PUBMED   22566498
REFERENCE   3  (bases 1 to 1881)
  AUTHORS   Ng,M.C., Hester,J.M., Wing,M.R., Li,J., Xu,J., Hicks,P.J.,
            Roh,B.H., Lu,L., Divers,J., Langefeld,C.D., Freedman,B.I.,
            Palmer,N.D. and Bowden,D.W.
  TITLE     Genome-wide association of BMI in African Americans
  JOURNAL   Obesity (Silver Spring) 20 (3), 622-627 (2012)
   PUBMED   21701570
REFERENCE   4  (bases 1 to 1881)
  AUTHORS   Wang,K.S., Liu,X.F. and Aragam,N.
  TITLE     A genome-wide meta-analysis identifies novel loci associated with
            schizophrenia and bipolar disorder
  JOURNAL   Schizophr Res 124 (1-3), 192-199 (2010)
   PUBMED   20889312
REFERENCE   5  (bases 1 to 1881)
  AUTHORS   Muzny,D.M., Scherer,S.E., Kaul,R., Wang,J., Yu,J., Sudbrak,R.,
            Buhay,C.J., Chen,R., Cree,A., Ding,Y., Dugan-Rocha,S., Gill,R.,
            Gunaratne,P., Harris,R.A., Hawes,A.C., Hernandez,J., Hodgson,A.V.,
            Hume,J., Jackson,A., Khan,Z.M., Kovar-Smith,C., Lewis,L.R.,
            Lozado,R.J., Metzker,M.L., Milosavljevic,A., Miner,G.R.,
            Morgan,M.B., Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z.,
            Steffen,D., Wei,S., Wheeler,D.A., Wright,M.W., Worley,K.C.,
            Yuan,Y., Zhang,Z., Adams,C.Q., Ansari-Lari,M.A., Ayele,M.,
            Brown,M.J., Chen,G., Chen,Z., Clendenning,J.,
            Clerc-Blankenburg,K.P., Chen,R., Chen,Z., Davis,C., Delgado,O.,
            Dinh,H.H., Dong,W., Draper,H., Ernst,S., Fu,G.,
            Gonzalez-Garay,M.L., Garcia,D.K., Gillett,W., Gu,J., Hao,B.,
            Haugen,E., Havlak,P., He,X., Hennig,S., Hu,S., Huang,W.,
            Jackson,L.R., Jacob,L.S., Kelly,S.H., Kube,M., Levy,R., Li,Z.,
            Liu,B., Liu,J., Liu,W., Lu,J., Maheshwari,M., Nguyen,B.V.,
            Okwuonu,G.O., Palmeiri,A., Pasternak,S., Perez,L.M., Phelps,K.A.,
            Plopper,F.J., Qiang,B., Raymond,C., Rodriguez,R.,
            Saenphimmachak,C., Santibanez,J., Shen,H., Shen,Y., Subramanian,S.,
            Tabor,P.E., Verduzco,D., Waldron,L., Wang,J., Wang,J., Wang,Q.,
            Williams,G.A., Wong,G.K., Yao,Z., Zhang,J., Zhang,X., Zhao,G.,
            Zhou,J., Zhou,Y., Nelson,D., Lehrach,H., Reinhardt,R., Naylor,S.L.,
            Yang,H., Olson,M., Weinstock,G. and Gibbs,R.A.
  TITLE     The DNA sequence, annotation and analysis of human chromosome 3
  JOURNAL   Nature 440 (7088), 1194-1198 (2006)
   PUBMED   16641997
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB199311.1 and AK026825.1.
            
            On May 17, 2019 this sequence version replaced NM_001164436.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK026825.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2158569 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000334567.9/ ENSP00000334072.5
            RefSeq Select criteria :: based on longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                DB199311.1         1-20
            21-1881             AK026825.1         1-1861
FEATURES             Location/Qualifiers
     source          1..1881
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q26.31"
     gene            1..1881
                     /gene="TMEM212"
                     /note="transmembrane protein 212"
                     /db_xref="GeneID:389177"
                     /db_xref="HGNC:HGNC:34295"
     exon            1..194
                     /gene="TMEM212"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..620
                     /gene="TMEM212"
                     /codon_start=1
                     /product="transmembrane protein 212"
                     /protein_id="NP_001157908.1"
                     /db_xref="CCDS:CCDS46958.1"
                     /db_xref="GeneID:389177"
                     /db_xref="HGNC:HGNC:34295"
                     /translation="MKGLYQAAGRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRI
                     ACPIWNGALAITTGVLLLLAYREWTQRYLGEATFTFVILSIMGCPLHFAIALESALLG
                     PYCFYSFSGIAGTNYLGYAVTFPYPYAKFPLACVDPPHYEEYHLTLQALDLCLSFTLL
                     CTSLTVFIKLSARLIQNGHINMQLPAGNPNPFSP"
     exon            195..254
                     /gene="TMEM212"
                     /inference="alignment:Splign:2.1.0"
     exon            255..578
                     /gene="TMEM212"
                     /inference="alignment:Splign:2.1.0"
     exon            579..623
                     /gene="TMEM212"
                     /inference="alignment:Splign:2.1.0"
     exon            624..1881
                     /gene="TMEM212"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atctttgaga ccaaggcctc aagccaccaa ggaaaatgaa gggcctctac caggctgctg
       61 gccggattct tgttactctg gggatcctca gtgtatgctc tggagttatt gctttctttc
      121 ctgtcttttc ttacaagcct tggttcacag gatggagtgt tcgaattgct tgtcctatct
      181 ggaatggagc tttggccatc acaactggtg tgcttctact gttggcttac agagagtgga
      241 cccagaggta cctgggggaa gctactttca cctttgtgat tctgagcatt atgggatgtc
      301 cacttcattt tgcaatagcc ttggaatctg ctctcctggg cccatattgc ttctattcat
      361 tttcagggat tgcagggact aattaccttg gctatgcagt tacctttcct tatccatatg
      421 caaaattccc attagcctgt gtggacccac cacactacga agagtaccac ctgacacttc
      481 aagccctaga cctgtgccta agctttaccc tactctgtac atccttgaca gtgttcatca
      541 aactttctgc aagacttatc cagaatggac acataaacat gcaactccct gctgggaacc
      601 caaacccttt ttcaccataa aagaattgga aaaaactaaa gttcatatgg gaccaaaaaa
      661 gagcccgcat acccaagaca atcctaagca aaaagaacaa agctggaggc atcacactac
      721 ctgacttcaa actattctac aaggctacag ttaccaaaac agcatggtac tggtaccaaa
      781 acagatatat agaccaatgg aacagaacag aggcctcaga aataacacca cacatataca
      841 accatctgat ctttgacaaa cctgacaaaa acaagaaatg gggaaaggat tcccttttta
      901 ataaatggtg ctgggaaaac tggttagcca tatgtagaaa gctgaaactg gatcccttcc
      961 ttacacctta tataaaaatt aactcaagat ggattaaaga cttaaatgta agacctaaaa
     1021 ccataaaaac cctagaagaa aacctaggca ataccattca ggacataggc atgggcaaag
     1081 acttcatgac taaaacacca aaagcaatgg caacaaaagc caaaatagac aaatcgtatc
     1141 taattaaact aaagggcttc tgcatggcaa aagaaactat catcagagtg aacaggcaac
     1201 ctacagaacg ggagaaaatt ttttcaatct acccatctga caaacagcta atatccagaa
     1261 tctacaaaga acttaaacaa atttacaaga aaaaaacaaa caaccacatc aaaaagtagg
     1321 caaaggacat ggacacttct caaaagaaga catttatgaa gccaacagac acacataatc
     1381 ccaaatcatg ctactataaa gacacatgca cacgtatgtt tattgcggca ctattcacaa
     1441 tagtaaagac ttggaaccaa cccaaatatc catcaatgat agattggatt aagaaaatgt
     1501 ggcacatata caccatggaa tactacgcag ccataaaaaa ggatgagttc atgtcctttg
     1561 cagggacata gatgaagctg gaaaccatca ttctccgcaa actgtcacaa ggacagaaaa
     1621 ccaaacacca catgttctca ctcataggtg ggaattgaac aatgggaaca cttggacaca
     1681 gggtggggaa catcacacac tggggccttt cagtgggtgg gaggctgggg gagggatagc
     1741 attaggagaa attcctaatg tagatgatga gttgatgggt gtggcaaacc aacatggcac
     1801 atatatacct atgcaacaaa cctgcatgtt gtgcacatgt accctagaac ttagagtata
     1861 ataaaaaaaa agaaaacagt g
//
