LOCUS       NM_001282477             590 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens transmembrane protein 210 (TMEM210), mRNA.
ACCESSION   NM_001282477 XM_003846333 XM_003846722 XM_003960464
VERSION     NM_001282477.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 590)
  AUTHORS   Pineau,C., Hikmet,F., Zhang,C., Oksvold,P., Chen,S., Fagerberg,L.,
            Uhlen,M. and Lindskog,C.
  TITLE     Cell Type-Specific Expression of Testis Elevated Genes Based on
            Transcriptomics and Antibody-Based Proteomics
  JOURNAL   J Proteome Res 18 (12), 4215-4230 (2019)
   PUBMED   31429579
REFERENCE   2  (bases 1 to 590)
  AUTHORS   Humphray,S.J., Oliver,K., Hunt,A.R., Plumb,R.W., Loveland,J.E.,
            Howe,K.L., Andrews,T.D., Searle,S., Hunt,S.E., Scott,C.E.,
            Jones,M.C., Ainscough,R., Almeida,J.P., Ambrose,K.D., Ashwell,R.I.,
            Babbage,A.K., Babbage,S., Bagguley,C.L., Bailey,J., Banerjee,R.,
            Barker,D.J., Barlow,K.F., Bates,K., Beasley,H., Beasley,O.,
            Bird,C.P., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.,
            Burrill,W., Burton,J., Carder,C., Carter,N.P., Chapman,J.C.,
            Chen,Y., Clarke,G., Clark,S.Y., Clee,C.M., Clegg,S., Collier,R.E.,
            Corby,N., Crosier,M., Cummings,A.T., Davies,J., Dhami,P., Dunn,M.,
            Dutta,I., Dyer,L.W., Earthrowl,M.E., Faulkner,L., Fleming,C.J.,
            Frankish,A., Frankland,J.A., French,L., Fricker,D.G., Garner,P.,
            Garnett,J., Ghori,J., Gilbert,J.G., Glison,C., Grafham,D.V.,
            Gribble,S., Griffiths,C., Griffiths-Jones,S., Grocock,R., Guy,J.,
            Hall,R.E., Hammond,S., Harley,J.L., Harrison,E.S., Hart,E.A.,
            Heath,P.D., Henderson,C.D., Hopkins,B.L., Howard,P.J., Howden,P.J.,
            Huckle,E., Johnson,C., Johnson,D., Joy,A.A., Kay,M., Keenan,S.,
            Kershaw,J.K., Kimberley,A.M., King,A., Knights,A., Laird,G.K.,
            Langford,C., Lawlor,S., Leongamornlert,D.A., Leversha,M., Lloyd,C.,
            Lloyd,D.M., Lovell,J., Martin,S., Mashreghi-Mohammadi,M.,
            Matthews,L., McLaren,S., McLay,K.E., McMurray,A., Milne,S.,
            Nickerson,T., Nisbett,J., Nordsiek,G., Pearce,A.V., Peck,A.I.,
            Porter,K.M., Pandian,R., Pelan,S., Phillimore,B., Povey,S.,
            Ramsey,Y., Rand,V., Scharfe,M., Sehra,H.K., Shownkeen,R.,
            Sims,S.K., Skuce,C.D., Smith,M., Steward,C.A., Swarbreck,D.,
            Sycamore,N., Tester,J., Thorpe,A., Tracey,A., Tromans,A.,
            Thomas,D.W., Wall,M., Wallis,J.M., West,A.P., Whitehead,S.L.,
            Willey,D.L., Williams,S.A., Wilming,L., Wray,P.W., Young,L.,
            Ashurst,J.L., Coulson,A., Blocker,H., Durbin,R., Sulston,J.E.,
            Hubbard,T., Jackson,M.J., Bentley,D.R., Beck,S., Rogers,J. and
            Dunham,I.
  TITLE     DNA sequence and analysis of human chromosome 9
  JOURNAL   Nature 429 (6990), 369-374 (2004)
   PUBMED   15164053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL929554.20 and AI208887.1.
            
            On Jun 2, 2019 this sequence version replaced NM_001282477.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            CCDS Note: This CCDS representation lacks full-length human
            transcript support. Its exon combination is therefore inferred, but
            it is supported by partial human transcripts including  AI208887.1,
            DR007981.1 and DR007982.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2151119
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000413619.3/ ENSP00000456333.2
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               AL929554.20        85203-85319         c
            118-145             AL929554.20        85012-85039         c
            146-520             AI208887.1         6-380               c
            521-590             AL929554.20        84121-84190         c
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.3"
     gene            1..590
                     /gene="TMEM210"
                     /note="transmembrane protein 210"
                     /db_xref="GeneID:100505993"
                     /db_xref="HGNC:HGNC:34059"
     exon            1..117
                     /gene="TMEM210"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..473
                     /gene="TMEM210"
                     /codon_start=1
                     /product="transmembrane protein 210 precursor"
                     /protein_id="NP_001269406.1"
                     /db_xref="CCDS:CCDS65197.1"
                     /db_xref="GeneID:100505993"
                     /db_xref="HGNC:HGNC:34059"
                     /translation="MAPGPWPVSCLRGGPLGLTYLSLLLIPAAAGTYCECSLGLSREA
                     LIALLVVLAGISASCFCALVIVAIGVLRAKGETCPRQVDNRLVENFGVQEDLMDLHPV
                     YVESQLMDADLEVSLVPPLEDQSLVAIPMEASSEEPPPPPPLPPE"
     exon            118..253
                     /gene="TMEM210"
                     /inference="alignment:Splign:2.1.0"
     exon            254..283
                     /gene="TMEM210"
                     /inference="alignment:Splign:2.1.0"
     exon            284..590
                     /gene="TMEM210"
                     /inference="alignment:Splign:2.1.0"
     regulatory      501..506
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM210"
                     /note="hexamer: ATTAAA"
     polyA_site      520
                     /gene="TMEM210"
                     /note="major polyA site"
     regulatory      571..576
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM210"
                     /note="hexamer: ATTAAA"
     polyA_site      590
                     /gene="TMEM210"
                     /note="major polyA site"
ORIGIN      
        1 agaggtgtgc agtggggcca gggctggaca tggcccccgg tccctggcct gtgtcctgcc
       61 tgcgtggtgg ccccttgggc ctcacatatt tgtcccttct gctcatccct gctgcagctg
      121 gaacctactg tgaatgcagc cttggcctca gccgcgaggc cctcatcgcc ctccttgtgg
      181 tgctggcggg catcagtgcc agctgcttct gtgccctcgt catcgtggca attggtgtct
      241 tgcgggccaa gggtgaaaca tgcccgagac aagtggacaa caggttggtg gagaattttg
      301 gggtccagga agatctcatg gacctgcacc cggtttacgt ggagtcccag ctaatggacg
      361 ctgacctgga ggtctccctg gtgccaccac tagaggatca gagccttgtg gccatcccca
      421 tggaggcttc ttcagaggag ccgccaccac ccccgcccct accacctgag tagagggctg
      481 agggcagctg ggggagggga attaaagcgt atttagtggc tgtgcactgt cctccctgca
      541 ggccctcctg agggcagctg ggggagggga attaaagctt gtttagtggt
//
