LOCUS       NM_001388354            1096 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens transmembrane protein 191C (TMEM191C), transcript
            variant 1, mRNA.
ACCESSION   NM_001388354
VERSION     NM_001388354.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP000557.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.107394.1,
                                           ERR279867.2838.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000536718.3/ ENSP00000490781.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-228               AP000557.2         37606-37833
            229-352             AP000557.2         38113-38236
            353-403             AP000557.2         38371-38421
            404-481             AP000557.2         38573-38650
            482-538             AP000557.2         38998-39054
            539-598             AP000557.2         39163-39222
            599-663             AP000557.2         39349-39413
            664-736             AP000557.2         39493-39565
            737-777             AP000557.2         39713-39753
            778-1096            AP000557.2         39836-40154
FEATURES             Location/Qualifiers
     source          1..1096
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.21"
     gene            1..1096
                     /gene="TMEM191C"
                     /note="transmembrane protein 191C"
                     /db_xref="GeneID:645426"
                     /db_xref="HGNC:HGNC:33601"
     exon            1..228
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..982
                     /gene="TMEM191C"
                     /note="isoform 1 is encoded by transcript variant 1;
                     KB-1323B2.6"
                     /codon_start=1
                     /product="transmembrane protein 191C isoform 1"
                     /protein_id="NP_001375283.1"
                     /db_xref="CCDS:CCDS93125.1"
                     /db_xref="GeneID:645426"
                     /db_xref="HGNC:HGNC:33601"
                     /translation="MAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQ
                     DLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQE
                     QWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQT
                     AEAWAIFQEQTVVLQEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMAR
                     ADRETRLFGGPRALAIRRCVLGALQVLLTLPLLFLGLSLLWTVLLDPGAVSAWLWSLT
                     SETTLRRLRYTLSPLLELRANGLLPT"
     exon            229..352
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     exon            353..403
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     exon            404..481
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     exon            482..538
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     exon            539..598
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     exon            599..663
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     exon            664..736
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     exon            737..777
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
     exon            778..1096
                     /gene="TMEM191C"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccattgtg acgcctgcca gccgcaggct gggtccccga ggcgggcggc atttaggctc
       61 ggtctccaca gccatggccg cgacgcagga gctgctgctg cagttgcaga aggataaccg
      121 agatggtcgc cagcggaagc aggagctaga gaagctgatg cgcgggctcg aggccgagag
      181 cgagagcctc aaccagcgcc tgcaggacct gagcgagcgg gagcggagcc tgctgcggag
      241 gcgaagccag gcagcgcagc ctctgcaagg ggaggcgcgc gaggcggcgc gggagcgcgc
      301 ggagcgggtg cgcagaagac tggaggaggc ggagcgccac aaggagtact tggagcagca
      361 cagcaggcag ctgcaggagc agtgggagga gctgtcgagt cagctcttct actacggagg
      421 ggaactgcag agccagaaga gcacggagca gcaactcgca gcccaattgg tgacgctgca
      481 gaatgaactg gagctggcgg agaccaaatg cgccttgcag gaggagaagc tgcagcagga
      541 cgcgctgcag acagcggagg cctgggccat attccaggag cagaccgtag tcctgcagga
      601 ggtgcaggtg aaggtgatgg aggctgcgga ggagctggac gcctggcaga gtggccggga
      661 actgtgtgac gggcagcttc gcggagtgca gtacagcacc gaatcgctca tggaggagat
      721 ggccagggcg gaccgagaga cgcggctgtt cggcggccct cgcgcgctgg ccatcaggcg
      781 gtgcgtgctg ggcgcgctgc aggtgctgct gacgctgccg ctcctcttcc tggggctgtc
      841 gctgctctgg acggtgctgt tggaccccgg cgccgtctcc gcgtggctct ggagcctcac
      901 ctcggagacg acgctgcgcc gcctgcgcta cacgctgtcc ccgctgctgg agctgcgcgc
      961 taacgggctt ctgccaacct aagtgcagcg ccccgcgcct ggctccaggt ggactccagg
     1021 gcacctggct ttatttctgg tgcactcctc tcctgagagt gtagaccaag gttgcctaat
     1081 aaactcaagg gatgaa
//
