LOCUS       NM_001242313            1334 bp    mRNA    linear   PRI 06-FEB-2024
DEFINITION  Homo sapiens transmembrane protein 191B (TMEM191B), mRNA.
ACCESSION   NM_001242313 XM_001128423 XM_003119843 XM_003119844 XM_003119845
            XM_003121003 XM_003121004 XM_003121005 XM_003121006 XM_003121007
            XM_003960911
VERSION     NM_001242313.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC023490.5.
            
            On or before Aug 31, 2013 this sequence version replaced
            XM_003960911.1, XM_003121004.1, XM_003121003.1, XM_003121007.1,
            XM_003121005.1, XM_003121006.1, XM_001128423.3, XM_003119844.1,
            XM_003119843.1, XM_003119845.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000612978.5/ ENSP00000481358.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-475               AC023490.5         44289-44763
            476-599             AC023490.5         45046-45169
            600-650             AC023490.5         45304-45354
            651-725             AC023490.5         45506-45580
            726-782             AC023490.5         45928-45984
            783-901             AC023490.5         46093-46211
            902-974             AC023490.5         46423-46495
            975-1015            AC023490.5         46643-46683
            1016-1334           AC023490.5         46742-47060
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.21"
     gene            1..1334
                     /gene="TMEM191B"
                     /note="transmembrane protein 191B"
                     /db_xref="GeneID:728229"
                     /db_xref="HGNC:HGNC:33600"
     exon            1..475
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..1220
                     /gene="TMEM191B"
                     /codon_start=1
                     /product="transmembrane protein 191B"
                     /protein_id="NP_001229242.1"
                     /db_xref="CCDS:CCDS74816.1"
                     /db_xref="GeneID:728229"
                     /db_xref="HGNC:HGNC:33600"
                     /translation="MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSV
                     STAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR
                     RRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEDLEQHSRQLQEQWEELSSQLFY
                     GGEPQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTV
                     VLQVRPHSDAKVPPASPPPDLGRCDGQLRGVQYSTESLMEEMARADRETRLFGGPRAL
                     AIRRCVLGALQVLLTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSP
                     LLELRANGLLPT"
     exon            476..599
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
     exon            600..650
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
     exon            651..725
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
     exon            726..782
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
     exon            783..901
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
     exon            902..974
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
     exon            975..1015
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1334
                     /gene="TMEM191B"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatcagtttg caagtgccat ctgcagtgtg ggggaaccaa tcttcaactt gcctgcattt
       61 ggtattagta ttttattaac ctttcattga tccaattacg gctctttgac acaattttca
      121 tcagtgatgg actaagtgtg atccggcctg acccgcctcc ggccggcgtg agaaggggca
      181 tgtgtcgggc tacgctcggg cttcccctgc cgcccattgt gatccagccc gctaggcgct
      241 ccctgccgcc cattgtgacg cctgccagcc gcaggctggg tccccgaggc gggcggcatt
      301 taggctcggt ctccacagcc atggccgcga cgcaggagct gctgctgcag ttgcagaagg
      361 ataaccgaga tggtcgccag cggaagcagg agctagagaa gctgatgcgc gggctcgagg
      421 ccgagagcga gagcctcaac cagcgcctgc aggacctgag cgagcgggag cggagcctgc
      481 tgcggaggcg aagccaggca gcgcagcctc tgcaagggga ggcgcgcgag gcggcgcggg
      541 agcgcgcgga gcgggtgcgc agaagactgg aggaggcgga gcgccacaag gaggacttgg
      601 agcagcacag caggcagctg caggagcagt gggaggagct gtcgagtcag ctcttctacg
      661 gaggggaacc gcagagccag aagagcacgg agcagcaact cgcagcccaa ttggtgacgc
      721 tgcagaatga actggagctg gcggagacca aatgcgcctt gcaggaggag aagctgcagc
      781 aggacgcgct gcagacagcg gaggcctggg ccatattcca ggagcagacc gtagtcctgc
      841 aggtgcggcc ccactcagac gccaaggtgc ctcccgcctc tcctccccca gacctggggc
      901 ggtgtgacgg gcagcttcgc ggagtgcagt acagcaccga gtcgctcatg gaggagatgg
      961 ccagggcgga ccgagagacg cggctgttcg gcggccctcg cgcgctggcc atcaggcggt
     1021 gcgtgctggg cgcgctgcag gtgctgctga cgctgccgct cctcttcctg gggctgtcgc
     1081 tgctctggac ggtgctgttg gaccccggcg ccgtctccgc gtggctctgg agcctcacct
     1141 cggagacgac gctgcgccgc ctgcgctaca cgctgtcccc gctgctggag ctgcgcgcta
     1201 acgggctgct gccaacctaa gtgcagcgcc ccgcgcctgg ctccaggtgg actccagggc
     1261 acctggcttt atttctggtg cactcctctc ctgagagtgt agaccaaggt tgcctaataa
     1321 actcaaggga tgaa
//
