LOCUS       XM_047419187            5533 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transmembrane protein 181 (TMEM181),
            transcript variant X10, mRNA.
ACCESSION   XM_047419187
VERSION     XM_047419187.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5533
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..5533
                     /gene="TMEM181"
                     /gene_synonym="GPR178; KIAA1423"
                     /note="transmembrane protein 181; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 166 long SRA reads, and 99% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     15 samples with support for all annotated introns"
                     /db_xref="GeneID:57583"
                     /db_xref="HGNC:HGNC:20958"
                     /db_xref="MIM:613209"
     CDS             687..1580
                     /gene="TMEM181"
                     /gene_synonym="GPR178; KIAA1423"
                     /codon_start=1
                     /product="transmembrane protein 181 isoform X10"
                     /protein_id="XP_047275143.1"
                     /db_xref="GeneID:57583"
                     /db_xref="HGNC:HGNC:20958"
                     /db_xref="MIM:613209"
                     /translation="MRLYTLSKRHFVLVFVVFFICFGLTIFVGIRGPKVIQTSAANFS
                     LNNSKKLKPIQILSNPLSTYNQQLWLTCVVELDQSKETSIKTSFPMTVKVDGVAQDGT
                     TMYIHNKVHNRTRTLTCAGKCAEIIVAHLGYLNYTQYTVIVGFEHLKLPIKGMNFTWK
                     TYNPAFSRLEIWFRFFFVVLTFIVTCLFAHSLRKFSMRDWGIEQKWMSVLLPLLLLYN
                     DPFFPLSFLVNSWLPGMLDDLFQSMFLCALLLFWLCVYHGIRVQGERKCLTFYLPKFF
                     IVGLLWLASVTLGIWQTRIGG"
     polyA_site      5533
                     /gene="TMEM181"
                     /gene_synonym="GPR178; KIAA1423"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 aggctctcag aggcgattgg tgacgtgggc accggggagc ctgccgcaac agcccctttg
       61 gactcggggt gtcgagttat atgagtttta tgcgttttac gatctgctga ctttgggctt
      121 tttttttttt ctttacctct ttgaagtcca gggtttttaa tgaggaaaaa cctgtttggg
      181 gtctcgtgga cgccatccct aaagcttgct tttgacccag cagtcgccta ggtgtccccc
      241 tgggcgcatc tggaaaagaa ggagacggag ttaaccagag ggttagcgcc gcgtggagtt
      301 gcagaaagtc cgggagaagg agtggcccat atgtgcagcc gcgcctggcg caggaggctt
      361 ccagggccgg ctccctgcac tgaaggcagc ctccgagggg cctgggcgcg cttcttggct
      421 tatatgcggt ttttgaggca gaagggtttt gctttggatc tttgctgatt tctctggctg
      481 tggacgtggt cagagaagtg acacccaggc ctgttgcctc agcgcaagtg cctgtgacag
      541 agagatctgt ttttccttct gcttccttag aagtttctga ctttggtatg ttgctttagc
      601 acctcttggg aaactggaat ggcatcaaat atcagaccta tgtggatgtt ttaaagattt
      661 taaaagccaa gtggaggctg gcgcccatgc ggctctacac gctctccaag cgccactttg
      721 tcctcgtgtt tgtcgtcttc ttcatctgct ttggcctgac catcttcgtt gggatcagag
      781 gacctaaagt gatccagact tctgcggcta atttttcact aaataatagc aaaaagctaa
      841 agccaattca aatactttca aatccactgt ctacatacaa tcagcaacta tggctgacat
      901 gtgttgttga gttggatcaa tcaaaagaaa cttctattaa gacaagcttt cccatgactg
      961 ttaaagtcga tggtgtagct caagatggaa ccacgatgta cattcataac aaagttcaca
     1021 accggacaag gaccctcaca tgtgcaggga aatgtgcgga gattattgtg gctcaccttg
     1081 gctacctgaa ctacactcag tatacagtga tagtgggatt tgaacacctg aagctcccca
     1141 tcaagggaat gaacttcaca tggaagactt ataaccctgc cttctcccgg ttggaaatct
     1201 ggttccggtt tttctttgtg gtgctcacct tcatcgtcac ttgcctgttt gcgcattccc
     1261 tccggaaatt ttccatgaga gactggggca tcgagcagaa gtggatgtct gttctcctgc
     1321 ctctgctgct actttacaat gatccgttct tccccctctc cttcctggtc aacagctggc
     1381 tcccagggat gctggatgac ctctttcagt ccatgttcct gtgcgccctg ctgctcttct
     1441 ggctgtgcgt gtaccacggg attcgtgtcc agggagaaag aaagtgttta actttctatt
     1501 tgcctaaatt cttcattgtt ggactattgt ggttggcttc tgttacgcta ggaatatggc
     1561 aaacacgaat aggagggtga ctttagtcac aggctgctca aaaacacagg ctgcagagaa
     1621 caggatttgg attggcaaac tcattgtacc ctcatgtcac actccttctt tgctcctacc
     1681 ttggagcatt ttggctggga ggcaaaaccc caatgctatt acaggcagtc cccttacccc
     1741 tcattccaca cccactaccc agaaactgaa gcctcatgac ccgctttgag gaaaaatatc
     1801 ccgtcctggt tttctgtgtt ccagtcggcc ttccaaacac atcctccccc tgggacacag
     1861 acttcaggcc agcctgtatt acgtcaggtt gctagttgcc cttttctggg agactcccaa
     1921 tgactgtgcc ctctctgctt aaagactgta gaggcaactg gtgttctcac gcaaagtggc
     1981 cagggtgtgg gagactagat ctttgactct ggcagtctcc aggactgtat gcaaggccag
     2041 gcccaggtgg gcatactggc aaaggctttt gggaacccgg ctagggagga agtagggagc
     2101 atccgtttcc atgatgattc tctccagtgg gatctgcctc agcacttccc gggcttctca
     2161 ggtggaggag tacgtcagga ctgccatgag gcccaccgac gttgggaaag tacttcagca
     2221 ggggttccat ggccaggtag ctgcagtgaa gcaatgcttg tgtatcttgt agtcagagaa
     2281 cacacatttt ctcatggtgt ccagcagatc ctcgtcagct tgctggcaga ggatcaccaa
     2341 agcttctcta gagacgcagc cagctcaagc tgtctcttaa ataccttgtg atgttctggg
     2401 acaggcatgg tgcacttgta ggagtaattg aagcctgttt ctccaaatgc cacagtcgtg
     2461 gggtgcctta aggcttgtaa aagatttctt tcctgactct tattgtagta acatggaaaa
     2521 tgagggtgac agccaaaggc cccccagacc agattctctt tcaacagctc cccccgtagg
     2581 caatttgtca gggtgagggt ggcagaggtc agagatgcaa ccctgaaatt ccttagagaa
     2641 ggagctgctg taaattcttc tgaacttagt caaggtccct ttgaaagaca acttggaata
     2701 cagcatatcc aaatgacagt gggtatcagt gaagccctgc tctaggcttg gctcccagtg
     2761 gctctttggc agggagctgg atgtgtgtcc tccacaagga cacagaggca tctcctcttg
     2821 gaatgttctt ctttgcttca cctcttttcc tcccgagctt ctggagaagt gaaatgagtg
     2881 agaattctgg gagctgcctt cctctgaggc ctccacatct ctggagacgt tatgggcgct
     2941 cactgcagag ttgggggaag aatcactcag gcactcgggc tgctcctccc agcctgtgct
     3001 gcgtcattgc tgctgctgct cacagacagg tagccggcag gcttggggct gctggtgcac
     3061 tagctgacat actcacacca aggactactg taaaaatgag gcaggtacat gacatagtag
     3121 tgaaggaaga aggctctgga atggctgagg gtttcagtgg gacgggttcc tcctgagaga
     3181 atctgaccgt ggagatctcc agatcagacc agttgcttcc tgaagagggg tgctccatca
     3241 ccacctccct atctttatgc tttcggattt ctaaatgaga gagtcatcca gaaactcgag
     3301 gggtggagag catttgtcag tgactgtcct ttggtcccca aggggctcct cagtgggttt
     3361 ctcctgaggg tctgtgacta ctctcctgtc acagaagctg ctcctctctg gcactgtctt
     3421 gtccttctcc actgacctct gggattgact atccttctca gcaggggtga ctgtgacact
     3481 cctggctgtt ccttctcagt cttggctggt ccttcactcc tagctggtcc ttctccacaa
     3541 ctgggacact ctgctatgct tggttttgaa ctagtgacag cctctccctt ccttttcggc
     3601 attgatttcc ctggatgccc tggttagcct ccaggtagat cattgtggag ccctgatgtc
     3661 gaagtctatc cgtcttcctt ttctggacct tgttgggttc ctcagtcgta tcattctgac
     3721 tctcagcttc agttgcaaat taagagttca tggagttacg agaactatct ttggaatcag
     3781 ccttaaagct gcaggcttcc ttttctagag aagctatttc ttctagaaag ggattggtag
     3841 gatgtggagg ggttccccct gacgaaagga ctccctgagt gctctgaatc aggcagcctt
     3901 tggtggcggc cccgcccaca cctgtgcccg aggaatgccg gggaggaatg taagagttaa
     3961 agaaaggaaa gaaacaggaa aagcggctca acagtcaaag acaggtttgt tttggacaat
     4021 aaacctgaga gggccttctg gccgagttag gtcagagtca ctctctctta caggctaaga
     4081 gtatttaagg gttcagggca gaagaggtta tcacaggctt ggaatgtttc tgtatctctt
     4141 cgccttgctt atctgggagg gggaggtttt gtgtctgttc ccatacaact ccctgcagct
     4201 gcagggatac cccccccacc tcctagtctg cttttagctt gtctatctta gcgcatttaa
     4261 agggaaagga atgtgcttat tagggcctac ttttttactg gggcccattt ttgggggccc
     4321 atttacactc ccaaaacatg agtgtgaagt tcggtggtta cccaagagac ttgggtgccc
     4381 agctgtgccc agctgtctta tctgtgtttt actgtctact ctttctggct gctttttgtt
     4441 agaagtgatt tccttgaaac gtaagaagtt agaaagggag ctggaactga aaatgggggt
     4501 gtttgtccaa gatgacggtg ctcctgctct gtcattccag accctatagt tataaaagga
     4561 ccaggggcga cgtgttcttt ctggttactt cctgctgggt gggagaggta gagagtccct
     4621 tggtctcgga ttgactgcgg gagcaatgcc gtctgtagat gttttggata gttgtctgtg
     4681 aaatagccat gctcctgtca gttaagaatc tttgaaaaag gttaattagg cagggtaaaa
     4741 acattagtcc taggcttatt attaggagag ggcccaggaa tgggatgacc catggtatgc
     4801 tttttgttcc caaaccaata attcatttgg ttgttttggt attcgcttag cattttagcc
     4861 ctttgtttga gatttttagc agcctctctt acgagacctg attggttgag atagaagcaa
     4921 catttctttc ccaatgagag gcagaggcac atgtttggaa agacccatgt gttatttttt
     4981 attagtaact gttattcctg ctgtaaggat agtaattaag caaaatgcta cggtaattga
     5041 gattgtctgt ctgatatcct accctcaggg tgctgcagta catagtccta ctgcaaatag
     5101 tccagtaaag cagttcccgc aagggtggca tggtaaataa tttccataaa aaagctttaa
     5161 tatttggctt aaaaggagag gtagaaatga caaaaagtac ttggtgaggt aagagtgaga
     5221 ctgagtcaga tgagtaattg tcactcagtt agttattttt tatgattttc aacttaagat
     5281 ttcttatttc tttacattga tatttaggac gttcctctgg gctgttggga ttgcttcctc
     5341 agcttttcag gctttgactt gagtgtgatg tatgcagggg ttgattcctg taacagatgt
     5401 aatttaaact gtcgaaaacc ataaaaattg aaaaacatca gtcaagacta gaatttaaca
     5461 ggtgtgctat agtttttgaa acctaatttt ctctctccag tttaccattt ttattaaaag
     5521 acaaatcata ata
//
