LOCUS       XM_011536003            5107 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transmembrane protein 181 (TMEM181),
            transcript variant X5, mRNA.
ACCESSION   XM_011536003
VERSION     XM_011536003.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011536003.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5107
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..5107
                     /gene="TMEM181"
                     /gene_synonym="GPR178; KIAA1423"
                     /note="transmembrane protein 181; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 140 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     16 samples with support for all annotated introns"
                     /db_xref="GeneID:57583"
                     /db_xref="HGNC:HGNC:20958"
                     /db_xref="MIM:613209"
     CDS             96..1154
                     /gene="TMEM181"
                     /gene_synonym="GPR178; KIAA1423"
                     /codon_start=1
                     /product="transmembrane protein 181 isoform X5"
                     /protein_id="XP_011534305.2"
                     /db_xref="GeneID:57583"
                     /db_xref="HGNC:HGNC:20958"
                     /db_xref="MIM:613209"
                     /translation="MDAEYPAFEPPLCSELKHLCRRLREAYRELKEDLTPFKDDRYYR
                     LAPMRLYTLSKRHFVLVFVVFFICFGLTIFVGIRGPKVIQTSAANFSLNNSKKLKPIQ
                     ILSNPLSTYNQQLWLTCVVELDQSKETSIKTSFPMTVKVDGVAQDGTTMYIHNKVHNR
                     TRTLTCAGANLSVYLQKCAEIIVAHLGYLNYTQYTVIVGFEHLKLPIKGMNFTWKTYN
                     PAFSRLEIWFRFFFVVLTFIVTCLFAHSLRKFSMRDWGIEQKWMSVLLPLLLLYNDPF
                     FPLSFLVNSWLPGMLDDLFQSMFLCALLLFWLCVYHGIRVQGERKCLTFYLPKFFIVG
                     LLWLASVTLGIWQTRIGG"
     polyA_site      5107
                     /gene="TMEM181"
                     /gene_synonym="GPR178; KIAA1423"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agcagcccga tccccagtgc tgggagaaga gagggggcgc aggcggcgac acaaagggtg
       61 gagcggcggg accgggaccc gggaggctgc gcggcatgga cgccgagtac cctgcctttg
      121 agcccccgct ctgcagcgag ctcaagcacc tgtgccggcg gctgcgggaa gcgtaccgcg
      181 agctcaagga ggacctcacg cccttcaagg atgaccgcta ctacaggctg gcgcccatgc
      241 ggctctacac gctctccaag cgccactttg tcctcgtgtt tgtcgtcttc ttcatctgct
      301 ttggcctgac catcttcgtt gggatcagag gacctaaagt gatccagact tctgcggcta
      361 atttttcact aaataatagc aaaaagctaa agccaattca aatactttca aatccactgt
      421 ctacatacaa tcagcaacta tggctgacat gtgttgttga gttggatcaa tcaaaagaaa
      481 cttctattaa gacaagcttt cccatgactg ttaaagtcga tggtgtagct caagatggaa
      541 ccacgatgta cattcataac aaagttcaca accggacaag gaccctcaca tgtgcagggg
      601 caaatctttc tgtgtatttg cagaaatgtg cggagattat tgtggctcac cttggctacc
      661 tgaactacac tcagtataca gtgatagtgg gatttgaaca cctgaagctc cccatcaagg
      721 gaatgaactt cacatggaag acttataacc ctgccttctc ccggttggaa atctggttcc
      781 ggtttttctt tgtggtgctc accttcatcg tcacttgcct gtttgcgcat tccctccgga
      841 aattttccat gagagactgg ggcatcgagc agaagtggat gtctgttctc ctgcctctgc
      901 tgctacttta caatgatccg ttcttccccc tctccttcct ggtcaacagc tggctcccag
      961 ggatgctgga tgacctcttt cagtccatgt tcctgtgcgc cctgctgctc ttctggctgt
     1021 gcgtgtacca cgggattcgt gtccagggag aaagaaagtg tttaactttc tatttgccta
     1081 aattcttcat tgttggacta ttgtggttgg cttctgttac gctaggaata tggcaaacac
     1141 gaataggagg gtgactttag tcacaggctg ctcaaaaaca caggctgcag agaacaggat
     1201 ttggattggc aaactcattg taccctcatg tcacactcct tctttgctcc taccttggag
     1261 cattttggct gggaggcaaa accccaatgc tattacaggc agtcccctta cccctcattc
     1321 cacacccact acccagaaac tgaagcctca tgacccgctt tgaggaaaaa tatcccgtcc
     1381 tggttttctg tgttccagtc ggccttccaa acacatcctc cccctgggac acagacttca
     1441 ggccagcctg tattacgtca ggttgctagt tgcccttttc tgggagactc ccaatgactg
     1501 tgccctctct gcttaaagac tgtagaggca actggtgttc tcacgcaaag tggccagggt
     1561 gtgggagact agatctttga ctctggcagt ctccaggact gtatgcaagg ccaggcccag
     1621 gtgggcatac tggcaaaggc ttttgggaac ccggctaggg aggaagtagg gagcatccgt
     1681 ttccatgatg attctctcca gtgggatctg cctcagcact tcccgggctt ctcaggtgga
     1741 ggagtacgtc aggactgcca tgaggcccac cgacgttggg aaagtacttc agcaggggtt
     1801 ccatggccag gtagctgcag tgaagcaatg cttgtgtatc ttgtagtcag agaacacaca
     1861 ttttctcatg gtgtccagca gatcctcgtc agcttgctgg cagaggatca ccaaagcttc
     1921 tctagagacg cagccagctc aagctgtctc ttaaatacct tgtgatgttc tgggacaggc
     1981 atggtgcact tgtaggagta attgaagcct gtttctccaa atgccacagt cgtggggtgc
     2041 cttaaggctt gtaaaagatt tctttcctga ctcttattgt agtaacatgg aaaatgaggg
     2101 tgacagccaa aggcccccca gaccagattc tctttcaaca gctccccccg taggcaattt
     2161 gtcagggtga gggtggcaga ggtcagagat gcaaccctga aattccttag agaaggagct
     2221 gctgtaaatt cttctgaact tagtcaaggt ccctttgaaa gacaacttgg aatacagcat
     2281 atccaaatga cagtgggtat cagtgaagcc ctgctctagg cttggctccc agtggctctt
     2341 tggcagggag ctggatgtgt gtcctccaca aggacacaga ggcatctcct cttggaatgt
     2401 tcttctttgc ttcacctctt ttcctcccga gcttctggag aagtgaaatg agtgagaatt
     2461 ctgggagctg ccttcctctg aggcctccac atctctggag acgttatggg cgctcactgc
     2521 agagttgggg gaagaatcac tcaggcactc gggctgctcc tcccagcctg tgctgcgtca
     2581 ttgctgctgc tgctcacaga caggtagccg gcaggcttgg ggctgctggt gcactagctg
     2641 acatactcac accaaggact actgtaaaaa tgaggcaggt acatgacata gtagtgaagg
     2701 aagaaggctc tggaatggct gagggtttca gtgggacggg ttcctcctga gagaatctga
     2761 ccgtggagat ctccagatca gaccagttgc ttcctgaaga ggggtgctcc atcaccacct
     2821 ccctatcttt atgctttcgg atttctaaat gagagagtca tccagaaact cgaggggtgg
     2881 agagcatttg tcagtgactg tcctttggtc cccaaggggc tcctcagtgg gtttctcctg
     2941 agggtctgtg actactctcc tgtcacagaa gctgctcctc tctggcactg tcttgtcctt
     3001 ctccactgac ctctgggatt gactatcctt ctcagcaggg gtgactgtga cactcctggc
     3061 tgttccttct cagtcttggc tggtccttca ctcctagctg gtccttctcc acaactggga
     3121 cactctgcta tgcttggttt tgaactagtg acagcctctc ccttcctttt cggcattgat
     3181 ttccctggat gccctggtta gcctccaggt agatcattgt ggagccctga tgtcgaagtc
     3241 tatccgtctt ccttttctgg accttgttgg gttcctcagt cgtatcattc tgactctcag
     3301 cttcagttgc aaattaagag ttcatggagt tacgagaact atctttggaa tcagccttaa
     3361 agctgcaggc ttccttttct agagaagcta tttcttctag aaagggattg gtaggatgtg
     3421 gaggggttcc ccctgacgaa aggactccct gagtgctctg aatcaggcag cctttggtgg
     3481 cggccccgcc cacacctgtg cccgaggaat gccggggagg aatgtaagag ttaaagaaag
     3541 gaaagaaaca ggaaaagcgg ctcaacagtc aaagacaggt ttgttttgga caataaacct
     3601 gagagggcct tctggccgag ttaggtcaga gtcactctct cttacaggct aagagtattt
     3661 aagggttcag ggcagaagag gttatcacag gcttggaatg tttctgtatc tcttcgcctt
     3721 gcttatctgg gagggggagg ttttgtgtct gttcccatac aactccctgc agctgcaggg
     3781 ataccccccc cacctcctag tctgctttta gcttgtctat cttagcgcat ttaaagggaa
     3841 aggaatgtgc ttattagggc ctactttttt actggggccc atttttgggg gcccatttac
     3901 actcccaaaa catgagtgtg aagttcggtg gttacccaag agacttgggt gcccagctgt
     3961 gcccagctgt cttatctgtg ttttactgtc tactctttct ggctgctttt tgttagaagt
     4021 gatttccttg aaacgtaaga agttagaaag ggagctggaa ctgaaaatgg gggtgtttgt
     4081 ccaagatgac ggtgctcctg ctctgtcatt ccagacccta tagttataaa aggaccaggg
     4141 gcgacgtgtt ctttctggtt acttcctgct gggtgggaga ggtagagagt cccttggtct
     4201 cggattgact gcgggagcaa tgccgtctgt agatgttttg gatagttgtc tgtgaaatag
     4261 ccatgctcct gtcagttaag aatctttgaa aaaggttaat taggcagggt aaaaacatta
     4321 gtcctaggct tattattagg agagggccca ggaatgggat gacccatggt atgctttttg
     4381 ttcccaaacc aataattcat ttggttgttt tggtattcgc ttagcatttt agccctttgt
     4441 ttgagatttt tagcagcctc tcttacgaga cctgattggt tgagatagaa gcaacatttc
     4501 tttcccaatg agaggcagag gcacatgttt ggaaagaccc atgtgttatt ttttattagt
     4561 aactgttatt cctgctgtaa ggatagtaat taagcaaaat gctacggtaa ttgagattgt
     4621 ctgtctgata tcctaccctc agggtgctgc agtacatagt cctactgcaa atagtccagt
     4681 aaagcagttc ccgcaagggt ggcatggtaa ataatttcca taaaaaagct ttaatatttg
     4741 gcttaaaagg agaggtagaa atgacaaaaa gtacttggtg aggtaagagt gagactgagt
     4801 cagatgagta attgtcactc agttagttat tttttatgat tttcaactta agatttctta
     4861 tttctttaca ttgatattta ggacgttcct ctgggctgtt gggattgctt cctcagcttt
     4921 tcaggctttg acttgagtgt gatgtatgca ggggttgatt cctgtaacag atgtaattta
     4981 aactgtcgaa aaccataaaa attgaaaaac atcagtcaag actagaattt aacaggtgtg
     5041 ctatagtttt tgaaacctaa ttttctctct ccagtttacc atttttatta aaagacaaat
     5101 cataata
//
