LOCUS       XM_011536001            5240 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transmembrane protein 181 (TMEM181),
            transcript variant X3, mRNA.
ACCESSION   XM_011536001
VERSION     XM_011536001.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011536001.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5240
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..5240
                     /gene="TMEM181"
                     /gene_synonym="GPR178; KIAA1423"
                     /note="transmembrane protein 181; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 9
                     mRNAs, 18 ESTs, 1158 long SRA reads, 1 Protein, and 94%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 16 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:57583"
                     /db_xref="HGNC:HGNC:20958"
                     /db_xref="MIM:613209"
     CDS             194..1699
                     /gene="TMEM181"
                     /gene_synonym="GPR178; KIAA1423"
                     /codon_start=1
                     /product="transmembrane protein 181 isoform X3"
                     /protein_id="XP_011534303.1"
                     /db_xref="GeneID:57583"
                     /db_xref="HGNC:HGNC:20958"
                     /db_xref="MIM:613209"
                     /translation="MRGQQRTQKREQNRQRRTSLWLAPMRLYTLSKRHFVLVFVVFFI
                     CFGLTIFVGIRGPKVIQTSAANFSLNNSKKLKPIQILSNPLSTYNQQLWLTCVVELDQ
                     SKETSIKTSFPMTVKVDGVAQDGTTMYIHNKVHNRTRTLTCAGANLSVYLQKCAEIIV
                     AHLGYLNYTQYTVIVGFEHLKLPIKGMNFTWKTYNPAFSRLEIWFRFFFVVLTFIVTC
                     LFAHSLRKFSMRDWGIEQKWMSVLLPLLLLYNDPFFPLSFLVNSWLPGMLDDLFQSMF
                     LCALLLFWLCVYHGIRVQGERKCLTFYLPKFFIVGLLWLASVTLGIWQTVNELHDPMY
                     QYRVDTGNFQGMKVFFMVVAAVYILYLLFLIVRACSELRHMPYVDLRLKFLTALTFVV
                     LVISIAILYLRFGAQVLQDNFVAELSTHYQNSAEFLSFYGLLNFYLYTLAFVYSPSKN
                     ALYESQLKDNPAFSMLNDSDDDVIYGSDYEEMPLQNGQAIRAKYKEESDSD"
ORIGIN      
        1 agtctctcag gcgtgtgctg cggggatgtg ggcacgcagg cccgtgtgag ctttggaccg
       61 tgaagccagt aaccttcctg cagggccagg ctgagcatac tatgtccatc tccctgggtg
      121 gacgtgcggc tgcctgtccc tgaggtgagg tgctcggtct ccttcccgct ggtctggctc
      181 ccaagaccag aacatgcgag gacaacagag aacacagaag agagagcaaa acagacagcg
      241 ccgcacgtcc ctctggctgg cgcccatgcg gctctacacg ctctccaagc gccactttgt
      301 cctcgtgttt gtcgtcttct tcatctgctt tggcctgacc atcttcgttg ggatcagagg
      361 acctaaagtg atccagactt ctgcggctaa tttttcacta aataatagca aaaagctaaa
      421 gccaattcaa atactttcaa atccactgtc tacatacaat cagcaactat ggctgacatg
      481 tgttgttgag ttggatcaat caaaagaaac ttctattaag acaagctttc ccatgactgt
      541 taaagtcgat ggtgtagctc aagatggaac cacgatgtac attcataaca aagttcacaa
      601 ccggacaagg accctcacat gtgcaggggc aaatctttct gtgtatttgc agaaatgtgc
      661 ggagattatt gtggctcacc ttggctacct gaactacact cagtatacag tgatagtggg
      721 atttgaacac ctgaagctcc ccatcaaggg aatgaacttc acatggaaga cttataaccc
      781 tgccttctcc cggttggaaa tctggttccg gtttttcttt gtggtgctca ccttcatcgt
      841 cacttgcctg tttgcgcatt ccctccggaa attttccatg agagactggg gcatcgagca
      901 gaagtggatg tctgttctcc tgcctctgct gctactttac aatgatccgt tcttccccct
      961 ctccttcctg gtcaacagct ggctcccagg gatgctggat gacctctttc agtccatgtt
     1021 cctgtgcgcc ctgctgctct tctggctgtg cgtgtaccac gggattcgtg tccagggaga
     1081 aagaaagtgt ttaactttct atttgcctaa attcttcatt gttggactat tgtggttggc
     1141 ttctgttacg ctaggaatat ggcaaacagt taacgaatta catgatccaa tgtaccagta
     1201 tcgagttgat accggaaatt ttcagggaat gaaggtcttc ttcatggtgg tggcagcggt
     1261 gtacattctg tacctcttgt tcttgatagt gcgggcgtgt tccgagctac gtcacatgcc
     1321 ttatgtggat ctcaggttga aatttttgac tgcattgact ttcgtagtac ttgtcattag
     1381 catcgccatc ctttatttga gatttggggc gcaagtacta caagacaatt ttgtagcaga
     1441 gctgtcaact cactaccaga attcagccga gttcttatct ttctatggcc tgttgaactt
     1501 ctatctctac accttggcct ttgtatattc tccatcgaag aatgccctct atgagtccca
     1561 gctgaaagac aatcctgcct tctccatgct gaatgactcg gatgatgatg tgatttatgg
     1621 gagtgactat gaggaaatgc cgctgcagaa cggccaggcc atccgggcca agtacaagga
     1681 ggagtcagat agtgactgag ccccggccag cccagcgagg cgacaagatg cctggatgct
     1741 ttccccggtg accgtctgct gaccttcccc tgttatattc agatttttct tacaagcaga
     1801 gatttcctgt tcatttgttt acatattttt ttaaaggaaa accaaaactg agggtaaatt
     1861 taaatgttta gccaaattta ttgtcatggt ggctacgaga agaggcattg ataacaagtt
     1921 tcaacagcca aatccttttt tacagagatt tcagatgagc gtgttttcag tgatgaggaa
     1981 atttcacgtt tttagtacag tgaattatgt actttttttt cctgtaatca ttcactgatt
     2041 ccaagttcac gggcagcctg tgactaggtc ctcagcgtga cagcatcacc ctctttcttc
     2101 ccttttccat ggtactgttt tgtgaccctt taaactcaaa gggaagcctt atctgtggct
     2161 gcttcagggc agtccttcct cgttgagtgg ccagtgccct gggtaaccag gtggctgaag
     2221 tgattggtca gttatgtgga ctgcgttttg tgcagtgtgt gagttatgac tcatcgggaa
     2281 tgggagatgc tggggttcca acccttcacg tcaccaaagg ggaagtaata gtgtggagtt
     2341 ctgaggaggg tttgataagt tgaataagga aaggctaaga taatttacag gttaccaact
     2401 catgtgggga aggtcttact gccatggtgc ttttcagggg cctgtgtgta cacacatgat
     2461 taaatggatt tgcctgtggg aggtatgggc aggagaggaa cccttaccat tccagtaaat
     2521 agcagtttct gcaattctgt tgaatatgaa atgccataga gctttattta tttatgtaag
     2581 taaaagctaa atgaggggcc aggtgcagtg gctcacatct gtaatctcaa cactttggga
     2641 ggccaaggtg ggaggatcac ttgagcccag gagtttgaga ccagcctggg caacacaggg
     2701 agaccccgtc tctataaaac atttagaaag ttggctgggc atgctggggc atgcccatag
     2761 tcccagctac tcaggaggct gaggtgggag gattgcttga gccctggagg tcaaggctgc
     2821 agtgagccat gattgcacca ctgcactcca gcctgggtgt cagagcgaga acccgtgtca
     2881 taaataaata aagctacatg aaagattgat agaatatttt agattattta ttggccaaaa
     2941 gtttttaaaa ctcatatttg gaagcaaaat gaaaagcaag taaaatgttt taaatggttc
     3001 atggaaaacg tatttgggta gaaggcaact cgtgcttccg gaaggggttc cctgtcctcc
     3061 atgtgtccac atggcggtca ggtagggacg acctgttctg taaagtcctt ggcactgctg
     3121 aatctgtggc atcatagaag gccctggagc ttccccgttc ctttcagtca gggactccat
     3181 atagagtctc atgtggacgt ctcccgtgct ttcctcttga cctctacagt cacacttctg
     3241 ttaacatctg gtaactgtgg gcaacctgac tgatgccgtc ttggcaattg aggtccagaa
     3301 gatgatagtt ccgcaacgca agcagtacct actttttttc ttcatctatg cattgactct
     3361 cagattacca tgcagagctt cacgttatca tccacgttaa gtagtgctag gtaggacctt
     3421 agagatgttc atgagaaact atttgttatg actttccttt gtatctttcc ttttaattta
     3481 aactttaatg ataatgtact tttaatatgg attctattca catttgtttt aaaaaccttg
     3541 taaatatgaa tgtttaagac aacttactgc aagggtaatt caagtttaca tgatttttaa
     3601 atttgcaatg atgttttttt tattctgtgt attgaaaaaa attttctgtt accaaatttt
     3661 acaacttcta ataagactac tataacttta tgtaaactga tgaagatgtg ctgattaaca
     3721 tattctgtga tatggtttac aacttttaat cataattgtc catgattttg gaatgctgtt
     3781 atttatcagt aaatgtaaaa tatttgaggc atttagccat acacacacta gaacttttta
     3841 aaactttgtc ctatagtgta attataaact gatgactatt atcttcatac attgagtctt
     3901 catgcatcaa tgaaatgaaa aatataggat tatttattta ctttttgtaa ctaagtggga
     3961 aataagaaaa aaagttagaa agtacttaag gggaaaatcg ttcttactaa gtcatgtatt
     4021 ttcaacttgt cttccctggt atatcataaa taccgacata ttacataccc catgtaaaat
     4081 tttgcttaaa ctctctagca cttggcatgt agaatatgta ccataggtat caggttaaaa
     4141 cactaaagtc tgccagaaac ttttgacagt agcaagaaaa ttgttgaaga aaaaataaat
     4201 tatttactga gggtagttat gttaaagttt tgcgaactta aagggctgac tttagttcct
     4261 tcatggtaat ggcttgagta acatcatctt tgggattttt taaatactgg tccagtctag
     4321 gagaacctgg aagatgacca gaggtatttc agtttcccta gggagagctt cgttatccat
     4381 gtggatgata agtctgcttg atttattatt aaatcattat agcagtgaag tggtgccatt
     4441 ttctctctct taagccccat ttgaaaggct agagaagggg atatatatac tatgttcaag
     4501 gtttgtaagg ttgttaatgt acataattgc agattgcaat aaaagcttag atacattttg
     4561 taaacccaac ccactaaatg agcaggttac aagacaaatg tcaccagcct caagtatttt
     4621 atgaactatt tactgagggt agttatgtta aatagattat aatgtggtaa attatttcct
     4681 gaatccttta tcacaggaaa aacacagacc ctcataaaag ggataattaa aacggatgtg
     4741 tctgaacatt tagtgaagat gagacttaaa acatgaaagt gtatttgtgt attttgaggg
     4801 ttttagaaac cggttgcctt agaggttaga cttttgaaga aaaaaaaaaa aagatacaga
     4861 tcttttcccc tggccaaagg gaagttgtat tagtctgtga catcttgtga tgctgtttat
     4921 cttggtttga cattggagat acgctagtaa ctgtgatacc atactataaa acagaagaat
     4981 tttctgctac taaaaactgc ctttttacaa aatgactgta aatatttgta aaataaaata
     5041 acactaaact ttaagcccaa aaggagagat agagccatgt gttcagttgt ggacctgtcc
     5101 gtggggcaca gtgccacccc atcacagtgt tgctgtcatc aggcaaaagt gaatgtttgt
     5161 ttatggcaaa ttcgtctttt gcgaatggct taattctgac actacctttc tgggaaatgt
     5221 taataaattt ttaatattca
//
