LOCUS       NM_024943               1923 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens transmembrane protein 156 (TMEM156), transcript
            variant 1, mRNA.
ACCESSION   NM_024943
VERSION     NM_024943.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1923)
  AUTHORS   Morrison,D., Arcese,A.A., Parrish,J., Gibbs,K., Beaufort,A.,
            Herman,P., Stein,A.B. and Bloom,O.
  TITLE     Systemic gene expression profiles according to pain types in
            individuals with chronic spinal cord injury
  JOURNAL   Mol Pain 17, 17448069211007289 (2021)
   PUBMED   33853401
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK026888.1, AC079921.5 and BC030803.1.
            
            On Nov 23, 2018 this sequence version replaced NM_024943.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC030803.1, AK026888.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000381938.4/ ENSP00000371364.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-698               AK026888.1         13-710
            699-699             AC079921.5         40669-40669         c
            700-1866            AK026888.1         712-1878
            1867-1923           BC030803.1         1820-1876
FEATURES             Location/Qualifiers
     source          1..1923
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4p14"
     gene            1..1923
                     /gene="TMEM156"
                     /note="transmembrane protein 156"
                     /db_xref="GeneID:80008"
                     /db_xref="HGNC:HGNC:26260"
     exon            1..184
                     /gene="TMEM156"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..987
                     /gene="TMEM156"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="transmembrane protein 156 isoform 1"
                     /protein_id="NP_079219.1"
                     /db_xref="CCDS:CCDS3448.1"
                     /db_xref="GeneID:80008"
                     /db_xref="HGNC:HGNC:26260"
                     /translation="MTKTALLKLFVAIVITFILILPEYFKTPKERTLELSCLEVCLQS
                     NFTYSLSSLNFSFVTFLQPVRETQIIMRIFLNPSNFRNFTRTCQDITGEFKMCSSCLV
                     CESKGNMDFISQEQTSKVLIRRGSMEVKANDFHSPCQHFNFSVAPLVDHLEEYNTTCH
                     LKNHTGRSTIMEDEPSKEKSINYTCRIMEYPNDCIHISLHLEMDIKNITCSMKITWYI
                     LVLLVFIFLIILTIRKILEGQRRVQKWQSHRDKPTSVLLRGSDSEKLRALNVQVLSAE
                     TTQRLPLDQVQEVLPPIPEL"
     exon            185..454
                     /gene="TMEM156"
                     /inference="alignment:Splign:2.1.0"
     exon            455..715
                     /gene="TMEM156"
                     /inference="alignment:Splign:2.1.0"
     exon            716..835
                     /gene="TMEM156"
                     /inference="alignment:Splign:2.1.0"
     exon            836..919
                     /gene="TMEM156"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1025
                     /gene="TMEM156"
                     /inference="alignment:Splign:2.1.0"
     exon            1026..1923
                     /gene="TMEM156"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1893..1898
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM156"
                     /note="hexamer: AATAAA"
     polyA_site      1923
                     /gene="TMEM156"
                     /note="major polyA site"
ORIGIN      
        1 gcattaacct aaagtgctgc agagataaac ttaaagcagg aagcaacata ccatgaatgt
       61 actgcaaggg aacacatttg tgtcatgtga agagacatga caaaaacagc cctccttaaa
      121 ttatttgtgg caatagtgat cacattcatt ttaattttgc cggaatattt caagacaccg
      181 aaagaaagaa cattggagct atcatgtctg gaagtgtgtt tgcaatctaa ttttacctat
      241 tcactctcct ccttaaattt ttcttttgtg acttttctgc aaccagtaag ggaaactcag
      301 attatcatga gaatctttct aaatccctcc aattttcgta acttcaccag gacttgccaa
      361 gacatcacag gtgaatttaa aatgtgctcc tcgtgtttgg tttgtgagtc taaaggaaac
      421 atggatttta tttctcagga acaaacatca aaagttctta tcaggagagg atcaatggaa
      481 gtgaaagcaa atgattttca ttcaccttgt cagcacttta acttcagtgt agctcctctg
      541 gttgaccact tggaggaata taacactacc tgtcatctaa aaaaccacac tggaagatca
      601 acaatcatgg aggatgagcc aagcaaggag aaatcgataa actacacttg tagaatcatg
      661 gaatacccga atgattgtat acacatttct ttgcacctag agatggatat aaaaaatatc
      721 acttgttcca tgaagatcac ttggtatatt ttagttctat tagtttttat atttttgatc
      781 atcctcacta tccgcaaaat acttgaaggc cagagaagag tgcaaaagtg gcagagtcat
      841 agagacaaac ctacatctgt tctcttaaga ggaagtgatt cggagaaact gagagcattg
      901 aatgtgcagg ttctttcagc agagaccacg cagaggctgc ctttggatca agtccaggaa
      961 gtgcttcccc caattccaga actataagtt acttccacag tgcatcagtg agatcaatat
     1021 acacgaatat ccccgggcaa gttggaccga gccctttgaa gaatactcag aagtttattt
     1081 tgtgaatgag tagactggaa aatgtttgtg tccagctgag gatgcacagt tggaaagcag
     1141 gaggaatgct gactggttga tgaaaactag cttaagagca ttcattcgct ccatgagatc
     1201 aagggaacaa gagtgtttgc aagaagccat tatgagtcat ggaaaaaaag atgatgaaac
     1261 ccatggaaac agcaagagaa ttcccactct ctctcttctt aaaaaaaatc tatcattata
     1321 cagcacagag tggagccaag tttttaattt tgaggaacca aaaacaggat caaatatgaa
     1381 aaccctttct tttattgggc cacattgtag atgctgattt gataattgtt tcctatgcag
     1441 atagattatt tttatttcac agattattta aaagggaaga gggcctggtt gtttatttat
     1501 atgtttgttt gcatttatga atcttgctgc cttttagcac caggatgttt ttaaaaaaat
     1561 tcaaagaggc caggcgcagt ggctcatgcc tgtaatccca gcactttggg attctgaggt
     1621 gggaggatca tgaggtcaag ggatcgagac catcctggcc aacatggtga aaccctgtct
     1681 ctactaaaaa cacaaaaatt agctgggtgt ggtggtgcgc gcctgtagtc ccagctcctc
     1741 aggaggctga ggcaggagaa tcacttgaac ctggcaggca gagtttgcag tgaaccaaga
     1801 tcacgccact gcattacagc ctggtgcaga gcaagactct gtctcaaaaa aaaaaaaaaa
     1861 aaaaaatcaa agataccaat aaaacgaatt taaataaaat acttaagtac tttaatagca
     1921 aaa
//
