LOCUS       NM_001137560            4911 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens transmembrane protein 151B (TMEM151B), mRNA.
ACCESSION   NM_001137560 XM_001723534 XM_001723740 XM_001725716
VERSION     NM_001137560.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4911)
  AUTHORS   Hosgood,H.D. 3rd, Zhang,L., Shen,M., Berndt,S.I., Vermeulen,R.,
            Li,G., Yin,S., Yeager,M., Yuenger,J., Rothman,N., Chanock,S.,
            Smith,M. and Lan,Q.
  TITLE     Association between genetic variants in VEGF, ERCC3 and
            occupational benzene haematotoxicity
  JOURNAL   Occup Environ Med 66 (12), 848-853 (2009)
   PUBMED   19773279
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 4911)
  AUTHORS   Tsai,J.Y., Namin-Gonzalez,M.L. and Silver,L.M.
  TITLE     False association of human ESTs
  JOURNAL   Nat Genet 8 (4), 321-322 (1994)
   PUBMED   7894479
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL139392.10, BC040881.1, BE671218.1, AL353588.25 and BM664874.1.
            
            On May 17, 2019 this sequence version replaced NM_001137560.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2145743,
                              SAMEA2154665 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000451188.7/ ENSP00000393161.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-293               AL139392.10        54927-55219
            294-356             AL139392.10        55220-55282
            357-869             BC040881.1         1-513
            870-1298            BE671218.1         55-483
            1299-2216           AL139392.10        60309-61226
            2217-4496           AL353588.25        101-2380
            4497-4911           BM664874.1         20-434              c
FEATURES             Location/Qualifiers
     source          1..4911
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p21.1"
     gene            1..4911
                     /gene="TMEM151B"
                     /gene_synonym="bA444E17.5; C6orf137; TMEM193"
                     /note="transmembrane protein 151B"
                     /db_xref="GeneID:441151"
                     /db_xref="HGNC:HGNC:21315"
     exon            1..428
                     /gene="TMEM151B"
                     /gene_synonym="bA444E17.5; C6orf137; TMEM193"
                     /inference="alignment:Splign:2.1.0"
     CDS             294..1994
                     /gene="TMEM151B"
                     /gene_synonym="bA444E17.5; C6orf137; TMEM193"
                     /note="transmembrane protein 193"
                     /codon_start=1
                     /product="transmembrane protein 151B"
                     /protein_id="NP_001131032.1"
                     /db_xref="CCDS:CCDS47437.1"
                     /db_xref="GeneID:441151"
                     /db_xref="HGNC:HGNC:21315"
                     /translation="MSPPGSAAGESAAGGGGGGGGPGVSEELTAAAAAAAADEGPARE
                     EQRPIQPSFTKSLCRESHWKCLLLSLLMYGCLGAVAWCHVTTVTRLTFSSAYQGNSLM
                     YHDSPCSNGYVYIPLAFLLMLYAVYLVECWHCQARHELQHRVDVSSVRERVGRMQQAT
                     PCIWWKAISYHYVRRTRQVTRYRNGDAYTTTQVYHERVNTHVAEAEFDYARCGVRDVS
                     KTLVGLEGAPATRLRFTKCFSFASVEAENAYLCQRARFFAENEGLDDYMEAREGMHLK
                     NVDFREFMVAFPDPARPPWYACSSAFWAAALLTLSWPLRVLAEYRTAYAHYHVEKLFG
                     LEGPGSASSAGGGLSPSDELLPPLTHRLPRVNTVDSTELEWHIRSNQQLVPSYSEAVL
                     MDLAGLGTRCGGAGGGYAPSCRYGGVGGPGAAGVAPYRRSCEHCQRAVSSSSIFSRSA
                     LSICASPRAGPGPGGGAGCGGSRFSLGRLYGSRRSCLWRSRSGSVNEASCPTEQTRLS
                     SQASMGDDEDDDEEEAGPPPPYHDALYFPVLIVHRQEGCLGHSHRPLHRHGSCVETSL
                     "
     exon            429..869
                     /gene="TMEM151B"
                     /gene_synonym="bA444E17.5; C6orf137; TMEM193"
                     /inference="alignment:Splign:2.1.0"
     exon            870..4911
                     /gene="TMEM151B"
                     /gene_synonym="bA444E17.5; C6orf137; TMEM193"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4887..4892
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM151B"
                     /gene_synonym="bA444E17.5; C6orf137; TMEM193"
                     /note="hexamer: AATAAA"
     polyA_site      4911
                     /gene="TMEM151B"
                     /gene_synonym="bA444E17.5; C6orf137; TMEM193"
                     /note="major polyA site"
ORIGIN      
        1 agacaaaagg cggcggcggg agcgggcggg aggcggagcg gcgccgcgag ggcctcaagg
       61 tgacacccgc ccccggcccc ggcccccccc ggcccggccc cccagcctgc ctcccaccct
      121 cagcccccag ccccttactc ccggtgccct ttccgggccc cctcccccgg cggggggtgg
      181 ggagcagcga gggccccgcc ccctcccgtc ctctccccag ggcccgcgca ggatgccccc
      241 ggcccctggc agccccccgg gaggtcctga gctcgacgcg ccccctctac gccatgtccc
      301 cccctggctc ggccgcggga gagagcgccg ccggcggcgg cggcggcggt ggcggccccg
      361 gggtctcgga ggagctcacg gcggcggcgg cagcggcggc ggcggacgag ggccccgccc
      421 gagaggagca gcgtcccatc cagccctctt tcaccaagtc cctctgccgt gagtcccact
      481 ggaagtgcct cctgctctcg ctgctcatgt acggctgcct gggggcagtg gcctggtgcc
      541 acgtcaccac agtgacgcgc ctcaccttca gcagcgccta ccagggcaac agcctcatgt
      601 accatgacag cccctgctcc aacggctatg tctacatccc cctggccttc ctgctcatgt
      661 tgtacgccgt ctacctggtg gagtgttggc actgccaagc ccgccatgag ctgcagcacc
      721 gtgttgatgt gagcagtgtg cgggaacgtg tgggccgcat gcagcaagcc acgccctgca
      781 tctggtggaa ggccatcagc taccactatg tccgccgcac ccgccaggtc accagatacc
      841 gcaatggaga cgcctatacc accacccagg tctaccacga acgcgtcaac acgcacgtgg
      901 cggaggctga gttcgactac gcgcgctgcg gcgttcgcga cgtgtccaag acgctggtgg
      961 ggctggaggg cgcgccggcc acgcggctgc gcttcaccaa gtgcttcagt ttcgccagcg
     1021 tggaggccga gaacgcgtac ctgtgccagc gcgcgcgctt cttcgcagag aacgagggcc
     1081 tagacgacta catggaggca cgcgagggca tgcacctcaa gaacgtggac ttccgtgagt
     1141 tcatggtggc cttcccggac ccggcccggc cgccctggta cgcctgctcg tcggccttct
     1201 gggccgcggc gctgctcacg ctgtcgtggc cgctgcgagt gctggccgag taccgcacgg
     1261 cctacgcgca ctaccacgtg gagaagctat ttggcctgga gggcccgggc tcggccagca
     1321 gcgcaggcgg tggcctcagc cccagcgatg agctgctgcc cccgctcacc caccgcctgc
     1381 cgcgggtcaa cacagtagac agcacggagc tcgagtggca catccgctcc aaccagcagc
     1441 tggtgcccag ctactctgag gcggtgctca tggacctggc ggggctcggg acgcgctgcg
     1501 gcggggcagg cggcggctac gcgccctcgt gccgctacgg tggggtaggc ggcccgggcg
     1561 cggcgggcgt ggctccctac cggcgcagct gcgagcactg ccagcgcgcc gtcagcagct
     1621 cgtctatctt ctcgcgcagc gccctaagca tctgcgccag cccgcgggcc ggcccggggc
     1681 ccggtggggg cgcgggctgc gggggcagcc gcttctcgct gggccgtctc tacggctccc
     1741 ggcgcagctg cctgtggcgc agccgcagcg ggagcgtcaa cgaggccagc tgccccacgg
     1801 agcagacgcg gctgtccagc caggccagca tgggggacga cgaggacgac gacgaggagg
     1861 aggccgggcc gccgccgccc taccacgacg ccctctactt tccggtcctc atcgtccacc
     1921 ggcaggaggg gtgtctgggc cacagccacc ggccgctgca ccgccacggc tcctgcgtag
     1981 agacctcact gtgacctccg gccccggagt ggcccgcgcc gtcctcccgc ctgcccctcg
     2041 ccggactgtg ctccctctgc gacgcagggc gagtcaccac ggtgactgag gccgcgcggg
     2101 gggcagggaa agggaggtga gggccgcaag acaggcccgg atggggccga gacccccgct
     2161 gtccctgtac ataaagagac cgatgggtgg gagggggtcg gctgctcccc gagatccccc
     2221 tggcagagtc attcttccag ccccaaccct gagttcctaa agggacacct ccctcctgtc
     2281 cagcccttca acagatcttc tgttagatga caaccgtgcc gtgggccccg cgttgggcct
     2341 tgtctgaagg gagaggccct ggcatgcgga tgggagattt agaggctgtg gagaagggaa
     2401 cttggggctt tccttccttc gtggcctcac tcccctgggg cctctctcta tggagggggc
     2461 aatggtttgg tgaccagcag gctggattcc aactagctaa tgcattcagc aggtctgagg
     2521 ctggggccag gtgtcagccc taggcctcca tccaacaccg tggaaatgtt gctgccctct
     2581 tcttggcgct gaccccaaga ttggggtttc ctttctgccg ctccctccac tgttgtttat
     2641 ctaactgggc ccccactcca ggtccagagg gactgtgctc actgcacaga catcactcac
     2701 cttccgctcc ccagtcctgc agagctgttg ccagggtgca gtggggaggg gagtgaaatg
     2761 tggaggactg tgtacctcag tcctctctct aaactcctca gcctcccaac aggggcctcc
     2821 tcacctgggt tctgagtgta tacccctttt agagagtgag atgccacccg ggcagcactc
     2881 gttaaagctg gccagcacga gtgactaagg ggagagagca tgacatagac ctgggtggca
     2941 acggggacct ctggaagcag gtgggagtaa gagaggagag ggcagtggag ggtagaggaa
     3001 aaggacctcc agaggtgggg tgtctgtggg ggcggccttt gcctccctaa acctgtgcgg
     3061 aggagtggag tgtgcttgtc gctcaaacac atctctgggg gactgaggac gttgtcacaa
     3121 gccccaactg gagaaataat tccaatggca gggtcagagg caagcattct ctaaatcttg
     3181 cccaaccctt ccatccttcc ctatcctatg agctgaagcc ctgctgtgtg tcgcagggtc
     3241 ttcaaagggg catcctgcca ccaccccagg gcgctggccc cacgtcctgt tcccctaaag
     3301 ctctgacacc gccttctctc cgtgtgctcc ccccaccacc tccaccctga tgtgcttcag
     3361 tgtgcatgtc tgtgaacagc cctcctgccc tgccaactcc cctggctaaa gtctccccag
     3421 cagatttagc acccagggat tgagctcaca tttcaggcta gagaggataa cccttgggcc
     3481 acccacatct ctcacccctg atgcttctta cttcgcctga gccatcagaa ctcctcctta
     3541 ccctccttca gcccctctca tcttccttca gcccagccag gcctgcacca ccaactgtgt
     3601 ggcctccacc tatgcaacat cgcctctggc tccccttccc ttcttcctag cggggagtgc
     3661 gaggggccca aattgtgggg ataccatggc ccatggcttc taaagggttt agctttactt
     3721 tcaggtagag atggctgagt gaggagggag aagaggctag agagagggag gcttgggcag
     3781 gggaaacagc tgcccaccag gttttcctgg acagcagtgc ccacctgcct actagcactg
     3841 aacctgcctg gaccctgagt ctgtgctcct tgggggcctg gcgtttggag cacccttctt
     3901 tcctctgaat ggacatctgt gaggtacagg tggtgagctg cagcctcagg ctccatttct
     3961 tagccagctg gcacctggat gtcatgcttt gtgtggggac agcctggcca cctcagggct
     4021 ccaaggaagg aggaacgtgg ctcctcctcc ctcaggcctg ttcctgagac agagcctggt
     4081 ctcacaagag gggaaggggg acctctatta ttatttttgc ctgtattgac catttctgcc
     4141 taggtcgtct cagacagcct catctcccac acatgcacag acttagagag aaaccaattc
     4201 tttggtctat tttcttggta gctttactga ttgccaggga aaatgaaaac cagaaaatta
     4261 attaatctct aaaattaaac tttacactga atgttcttgt ttctctaatt agaacttctg
     4321 ctagcagctg tggctataca cacacacaca cacacacaca ccctcacacc tacacgtttg
     4381 cactccggaa ctgtcagagg gtgtcaggca cagacagact ctaggttgcc tagacaggca
     4441 cacacatgca gtcactccca agcccccttt ggtgctctgc tcagcgcctg cttagcggaa
     4501 ggagtccctg gagagcaggc actcctggac tggggttgta gcccatgacc tgccctttgg
     4561 ggacacagtt ctggaggctc tgggccaatg aatcagccca aggaggatgg gcaatggcgc
     4621 tcagcctgaa tcagtcagct aggtctcttg tggccctggg ggctgatgtg attcctgtag
     4681 gtgtggcccc agggtggaca gctacagagt gatgggggac tcatgtaggg cacctggaag
     4741 gctccatgtg tcctggggac aagggcttgt ggggtgggct gggcctggct ggggagaaga
     4801 caggtctctg tcaattgggt gcatcacact gtggcctttt tgtcgtggat ttaagcgcaa
     4861 agattgtaca aatcaaactg gtggataata aagtcgtgga tgactcactg a
//
