LOCUS       NM_018342               3210 bp    mRNA    linear   PRI 08-JUN-2024
DEFINITION  Homo sapiens transmembrane protein 144 (TMEM144), mRNA.
ACCESSION   NM_018342
VERSION     NM_018342.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3210)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 3210)
  AUTHORS   Prentice,L.M., d'Anglemont de Tassigny,X., McKinney,S., Ruiz de
            Algara,T., Yap,D., Turashvili,G., Poon,S., Sutcliffe,M., Allard,P.,
            Burleigh,A., Fee,J., Huntsman,D.G., Colledge,W.H. and Aparicio,S.A.
  TITLE     The testosterone-dependent and independent transcriptional networks
            in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not
            fully equivalent
  JOURNAL   BMC Genomics 12, 209 (2011)
   PUBMED   21527035
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC098679.3 and BC054487.1.
            
            On May 17, 2019 this sequence version replaced NM_018342.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence data to make the sequence
            consistent with the reference genome assembly. The extent of this
            RefSeq transcript is supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.7905.1, SRR1660807.381.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000296529.11/ ENSP00000296529.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                AC098679.3         112437-112451
            16-2251             BC054487.1         1-2236
            2252-3081           AC098679.3         156409-157238
            3082-3210           AC098679.3         157239-157367
FEATURES             Location/Qualifiers
     source          1..3210
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q32.1"
     gene            1..3210
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /note="transmembrane protein 144"
                     /db_xref="GeneID:55314"
                     /db_xref="HGNC:HGNC:25633"
                     /db_xref="MIM:620325"
     exon            1..101
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            102..223
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            224..392
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     CDS             284..1321
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /codon_start=1
                     /product="transmembrane protein 144"
                     /protein_id="NP_060812.2"
                     /db_xref="CCDS:CCDS3799.1"
                     /db_xref="GeneID:55314"
                     /db_xref="HGNC:HGNC:25633"
                     /db_xref="MIM:620325"
                     /translation="MSNNGADLTFGYISCFVAILLFGSNFVPLKKFDTGDGMFLQWVL
                     CAAIWLVALVVNLILHCPKFWPFAMLGGCIWATGNIAVVPIIKTIGLGLGILIWGSFN
                     ALTGWASSRFGWFGLDAEEVSNPLLNYIGAGLSVVSAFIFLFIKSEIPNNTCSMDTTP
                     LITEHVINTTQDPCSWVDKLSTVHHRIVGCSLAVISGVLYGSTFVPIIYIKDHSKRND
                     SIYAGASQYDLDYVFAHFSGIFLTSTVYFLAYCIAMKNSPKLYPEAVLPGFLSGVLWA
                     IATCCWFIANHSLSAVVSFPIITAGPGFIAAMWGIFMFKEIKGLQNYLLMILAFCIIL
                     TGALCTAFSKI"
     exon            393..515
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            516..615
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            616..696
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            697..778
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            779..846
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            847..965
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1085
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1183
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1237
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..3210
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2980..2985
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /note="hexamer: AATAAA"
     polyA_site      2998
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
     regulatory      3059..3064
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /note="hexamer: AATAAA"
     polyA_site      3077
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /note="major polyA site"
     regulatory      3095..3100
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
                     /note="hexamer: AATATA"
     polyA_site      3113
                     /gene="TMEM144"
                     /gene_synonym="SLC35G7"
ORIGIN      
        1 gtagagggaa tgagtcaggc tccggctcca cactggcacg tagtgggcgg atcgcgccgg
       61 cgctgagtag gaaggagctt cagccgccag cccggaacgc atcataggtt agcttttcaa
      121 gacacttcct gcatctctga cctgttgcac ctctgttatc ttggcacctc tgttatctta
      181 gcagcaagca cctgcctcag ctgacccttg agccataacc cataagctcc tgaaaagtac
      241 atcaagtcta aagtgaacca gctaactcat taagactgga atcatgagca acaatggagc
      301 agacctaacc tttggttaca tctcctgttt tgtagctatc cttttgtttg gctcaaattt
      361 tgtgccactt aaaaaatttg atactggtga tggaatgttt ctccagtggg ttctttgtgc
      421 tgccatatgg ttggttgcct tggttgtcaa tctgatatta cattgtccaa agttttggcc
      481 ttttgcaatg cttgggggct gcatttgggc aacagggaac attgctgttg tcccaattat
      541 caaaaccatt ggtttaggcc ttggaatctt aatctgggga tcatttaatg ccttaactgg
      601 ctgggcaagc tcaaggtttg gctggtttgg attggatgca gaagaagtat caaatccgct
      661 gctaaattac attggagctg ggctatcagt agtaagtgct ttcatatttt tgttcatcaa
      721 aagtgaaata ccaaataaca cgtgttccat ggataccact ccattaataa cagagcatgt
      781 gatcaacaca acccaagacc cctgttcctg ggtggataaa ctttctacag tacaccaccg
      841 catagtgggc tgcagtcttg cagtgatatc tggagtactc tatggatcta catttgtgcc
      901 aatcatctac atcaaggacc acagcaaaag aaatgatagt atatatgcag gggcaagcca
      961 atatgattta gactatgtgt ttgcgcactt cagtggcatc tttcttacaa gtactgtcta
     1021 ctttctggcc tactgcatag ccatgaaaaa tagtcctaaa ctatatcctg aagcagtcct
     1081 accaggattc ctgtcaggag tactttgggc tatagctacc tgctgttggt tcatagcaaa
     1141 tcactctctg agtgctgtgg tcagttttcc aataatcact gctggtccag gatttatagc
     1201 tgcaatgtgg ggtatcttca tgtttaagga aataaagggt ctacaaaact acctattaat
     1261 gatacttgca ttttgcatca tcttgactgg agccttatgc actgcttttt ctaaaatcta
     1321 acaatgacaa aaccagcagg tggcagcagt agttaagaga acgcgtctat cggacagcgg
     1381 agagatcatg ctgagaaaag agtgcatttt catatagcaa atggatctca gccactgttg
     1441 gagtgggtaa atgatttttt tccccaaaaa tgtgagaatg aaggaagatt gagtttcatt
     1501 caagtataaa aatgaaaatt tcttctgatg aactgtttat gaaggtagta ctttactggg
     1561 tgactaaaat gtctacatta ttatagcatt acatacgagg atgctctttt taccacagta
     1621 tgtacctagt gttgcataat ctagaacaca gtatagagtc catatacaaa gaagttacag
     1681 tccatatttc tcacctatta ccccagtgaa gtgaggcaga aataccttgg gcgaggaggg
     1741 agagccttac cttctaatgg aattagattc caaagatatt tggatccttt gtttcataaa
     1801 gtaaatgcat agttggtaac taaatgttaa aaaggccatt ttattattgt tagccaaaac
     1861 ttctgtttat ttcaagttaa tatcgcccaa ctctacatca tctacccatt ttagctcata
     1921 atgcttttga ttatcgccag ataaagtcca ttctcagaga acaaaaattt ttcatcattg
     1981 agaaaatgtg cataacataa tacatacata cacaagtata ttcacgtaca taaatacaca
     2041 cagatatgtt gctaaagtga gattgtaggt tatcagtaac aatttaaagg aaacaaccac
     2101 tcttttgaat gtacaacttt tttttctgaa atacactttt ctaaaaccct cttaactgga
     2161 ggtttcctgt tttcttcttg ttttaactgg tggtttccag taggcaaaat aaaatgacag
     2221 gcatgctagt tttttttttt tttttttttt tttaagaaaa ctgaaattaa gccaggcagg
     2281 gtggcgcact actataatcc cagctgctgg ggcggctgaa gtaggagggt cacttagccc
     2341 aagagtgcaa atctgccagc ctaggcaaca tagcaaggtc ccatctctaa aaaagaaatt
     2401 taatttaaat ttgtaagaaa aaagaaaact gaaacagaac tgccagtaca atgtttgttg
     2461 caattgtttc caaaactttg agataacgaa acccctattc aaatgtaaat tttacccatt
     2521 cccacctgat agtactgttt attactttgc tatgcaggag aaacaaaaca gctttttatt
     2581 tgtgtgtata ctctgaagtc aatgtgcatg ggttaaatcc cacctctgct tcattttatt
     2641 tgtgtggctt tggacaagtt cctaagccct ctgtgtcagg cccctcatta acaaaatgga
     2701 gtttatgatg gcatctacct cacatggtta ttgtgtggtt gaaattagtt caaatctgta
     2761 aagtatgttg atgagtatct ggtacttggc aaacactata taattgttag ctttattatt
     2821 atgtgttgtt tgaaggggaa aaaagttttt gtagattgga gaacaccatg taagagctac
     2881 taagctcacc accttcccat ccaaacaatt attactcctc taaatgaata ctacttaaaa
     2941 gtgatggagc ttctgtttgt ttattgaatt gctaatacaa ataaatattt gactataact
     3001 tcttatactc attttaattt taacctgaaa tgtcattaaa ttatgctgat aaactttgaa
     3061 taaattgtga tacaaaagct atttttctca tttaaatata ttttagaatt ttatattgga
     3121 taacttttaa ttattcttta gttgggattt ccaatttata tgcaaaattt taaatgtgaa
     3181 gtaaagcagt ttcagaagaa aaatgaaaaa
//
