LOCUS       NM_133448               6135 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens transmembrane protein 132D (TMEM132D), mRNA.
ACCESSION   NM_133448 XM_062545
VERSION     NM_133448.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6135)
  AUTHORS   Chuang,H.K., Hsieh,A.R., Ang,T.Y., Chen,S.W., Yang,Y.P.,
            Huang,H.J., Chiou,S.H., Lin,T.C., Chen,S.J., Hsu,C.C. and
            Hwang,D.K.
  TITLE     TMEM132D and VIPR2 Polymorphisms as Genetic Risk Loci for Retinal
            Detachment: A Genome-Wide Association Study and Polygenic Risk
            Score Analysis
  JOURNAL   Invest Ophthalmol Vis Sci 64 (12), 17 (2023)
   PUBMED   37695605
  REMARK    GeneRIF: TMEM132D and VIPR2 Polymorphisms as Genetic Risk Loci for
            Retinal Detachment: A Genome-Wide Association Study and Polygenic
            Risk Score Analysis.
REFERENCE   2  (bases 1 to 6135)
  AUTHORS   Wang,X., Jiang,W., Luo,S., Yang,X., Wang,C., Wang,B., Dang,Y.,
            Shen,Y. and Ma,D.K.
  TITLE     The C. elegans homolog of human panic-disorder risk gene TMEM132D
            orchestrates neuronal morphogenesis through the WAVE-regulatory
            complex
  JOURNAL   Mol Brain 14 (1), 54 (2021)
   PUBMED   33726789
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6135)
  AUTHORS   Sanchez-Pulido,L. and Ponting,C.P.
  TITLE     TMEM132: an ancient architecture of cohesin and immunoglobulin
            domains define a new family of neural adhesion molecules
  JOURNAL   Bioinformatics 34 (5), 721-724 (2018)
   PUBMED   29088312
REFERENCE   4  (bases 1 to 6135)
  AUTHORS   Naik,R.R., Sotnikov,S.V., Diepold,R.P., Iurato,S., Markt,P.O.,
            Bultmann,A., Brehm,N., Mattheus,T., Lutz,B., Erhardt,A.,
            Binder,E.B., Schmidt,U., Holsboer,F., Landgraf,R. and Czibere,L.
  TITLE     Polymorphism in Tmem132d regulates expression and anxiety-related
            behavior through binding of RNA polymerase II complex
  JOURNAL   Transl Psychiatry 8 (1), 1 (2018)
   PUBMED   29317594
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6135)
  AUTHORS   Shimada-Sugimoto,M., Otowa,T., Miyagawa,T., Khor,S.S., Omae,Y.,
            Toyo-Oka,L., Sugaya,N., Kawamura,Y., Umekage,T., Miyashita,A.,
            Kuwano,R., Kaiya,H., Kasai,K., Tanii,H., Okazaki,Y., Tokunaga,K.
            and Sasaki,T.
  TITLE     Polymorphisms in the TMEM132D region are associated with panic
            disorder in HLA-DRB1*13:02-negative individuals of a Japanese
            population
  JOURNAL   Hum Genome Var 3, 16001 (2016)
   PUBMED   27081567
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6135)
  AUTHORS   Quast,C., Altmann,A., Weber,P., Arloth,J., Bader,D., Heck,A.,
            Pfister,H., Muller-Myhsok,B., Erhardt,A. and Binder,E.B.
  TITLE     Rare variants in TMEM132D in a case-control sample for panic
            disorder
  JOURNAL   Am J Med Genet B Neuropsychiatr Genet 159B (8), 896-907 (2012)
   PUBMED   22911938
  REMARK    GeneRIF: data suggest that not only common but also putatively
            functional and/or rare variants within TMEM132D might contribute to
            the risk to develop anxiety disorders
REFERENCE   7  (bases 1 to 6135)
  AUTHORS   Mick,E., McGough,J., Loo,S., Doyle,A.E., Wozniak,J., Wilens,T.E.,
            Smalley,S., McCracken,J., Biederman,J. and Faraone,S.V.
  TITLE     Genome-wide association study of the child behavior checklist
            dysregulation profile
  JOURNAL   J Am Acad Child Adolesc Psychiatry 50 (8), 807-17 (2011)
   PUBMED   21784300
  REMARK    GeneRIF: We found no genome-wide statistically significant
            associations but identified several plausible candidate genes among
            findings at p < 5E-05: TMEM132D, LRRC7, SEMA3A, ALK, and STIP1.
REFERENCE   8  (bases 1 to 6135)
  AUTHORS   Erhardt,A., Czibere,L., Roeske,D., Lucae,S., Unschuld,P.G.,
            Ripke,S., Specht,M., Kohli,M.A., Kloiber,S., Ising,M., Heck,A.,
            Pfister,H., Zimmermann,P., Lieb,R., Putz,B., Uhr,M., Weber,P.,
            Deussing,J.M., Gonik,M., Bunck,M., Kebler,M.S., Frank,E.,
            Hohoff,C., Domschke,K., Krakowitzky,P., Maier,W., Bandelow,B.,
            Jacob,C., Deckert,J., Schreiber,S., Strohmaier,J., Nothen,M.,
            Cichon,S., Rietschel,M., Bettecken,T., Keck,M.E., Landgraf,R.,
            Muller-Myhsok,B., Holsboer,F. and Binder,E.B.
  TITLE     TMEM132D, a new candidate for anxiety phenotypes: evidence from
            human and mouse studies
  JOURNAL   Mol Psychiatry 16 (6), 647-663 (2011)
   PUBMED   20368705
  REMARK    GeneRIF: TMEM132D may be an important new candidate gene for PD as
            well as more generally for anxiety-related behavior.
REFERENCE   9  (bases 1 to 6135)
  AUTHORS   Hendrickx,A., Beullens,M., Ceulemans,H., Den Abt,T., Van Eynde,A.,
            Nicolaescu,E., Lesage,B. and Bollen,M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
REFERENCE   10 (bases 1 to 6135)
  AUTHORS   Nomoto,H., Yonezawa,T., Itoh,K., Ono,K., Yamamoto,K., Oohashi,T.,
            Shiraga,F., Ohtsuki,H. and Ninomiya,Y.
  TITLE     Molecular cloning of a novel transmembrane protein MOLT expressed
            by mature oligodendrocytes
  JOURNAL   J Biochem 134 (2), 231-238 (2003)
   PUBMED   12966072
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC055717.36, AB061814.1, BC114626.1 and AC107033.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_133448.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB061814.1, BC114626.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000422113.7/ ENSP00000408581.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-358               AC055717.36        131328-131685
            359-398             AC055717.36        131686-131725
            399-2443            AB061814.1         42-2086
            2444-3177           BC114626.1         2086-2819
            3178-4411           AB061814.1         2821-4054
            4412-6135           AC107033.3         147556-149279
FEATURES             Location/Qualifiers
     source          1..6135
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.33"
     gene            1..6135
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /note="transmembrane protein 132D"
                     /db_xref="GeneID:121256"
                     /db_xref="HGNC:HGNC:29411"
                     /db_xref="MIM:611257"
     exon            1..765
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     CDS             687..3986
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /note="mature OL transmembrane protein; mature
                     oligodendrocytes transmembrane protein; protein
                     phosphatase 1, regulatory subunit 153"
                     /codon_start=1
                     /product="transmembrane protein 132D precursor"
                     /protein_id="NP_597705.2"
                     /db_xref="CCDS:CCDS9266.1"
                     /db_xref="GeneID:121256"
                     /db_xref="HGNC:HGNC:29411"
                     /db_xref="MIM:611257"
                     /translation="MCPSEMGTLWHHWSPVLISLAALFSKVTEGRGILESIQRFSLLP
                     TYLPVTYHINNADVSFFLKEANQDIMRNSSLQSRVESFLIYKSRRLPVLNASYGPFSI
                     EQVVPQDLMLPSNPFGFTNKFSLNWKLKAHILRDKVYLSRPKVQVLFHIMGRDWDDRS
                     AGEKLPCLRVFAFRETREVRGSCRLQGDLGLCVAELELLSSWFSPPTVVAGRRKSVDQ
                     PEGTPVELYYTVHPGGERGDCVREDARRSNGIRTGHSDIDESGPPLQRIGSIFLYQTH
                     RKPSLRELRLDNSVAIHYIPKTVRKGDVLTFPVSISRNSTEDRFTLRAKVKKGVNIIG
                     VRASSPSIWDVKERTDYTGKYAPAVIVCQKKAAGSENSADGASYEVMQIDVEVEEPGD
                     LPATQLVTWQVEYPGEITSDLGVSKIYVSPKDLIGVVPLAMEAEILNTAILTGKTVAV
                     PVKVVSVEDDGTVTELLESVECRSSDEDVIKVSDRCDYVFVNGKEMKGKVNVVVNFTY
                     QHLSSPLEMTVWVPRLPLQIEVSDTELNQIKGWRVPIVSSRRPAGDSEEEEDDERRGR
                     GCTLQYQHAMVRVLTQFVAEAAGPGGHLAHLLGSDWQVDITELINDFMQVEEPRIAKL
                     QGGQILMGQELGMTTIQILSPLSDTILAEKTITVLDEKVTITDLGVQLVTGLSLSLQL
                     SPGSNRAIFATAVAQELLQRPKQEAAISCWVQFSDGSVTPLDIYDGKDFSLMATSLDE
                     KVVSIHQDPKFKWPIIAAETEGQGTLVKVEMVISESCQKSKRKSVLAVGTANIKVKFG
                     QNDANPNTSDSRHTGAGVHMENNVSDRRPKKPSQEWGSQEGQYYGSSSMGLMEGRGTT
                     TDRSILQKKKGQESLLDDNSHLQTIPSDLTSFPAQVDLPRSNGEMDGNDLMQASKGLS
                     DLEIGMYALLGVFCLAILVFLINCVTFALKYRHKQVPFEEQEGMSHSHDWVGLSNRTE
                     LLENHINFASSQDEQITAIDRGMDFEESKYLLSTNSQKSINGQLFKPLGPIIIDGKDQ
                     KSEPPTSPTSKRKRVKFTTFTAVSSDDEYPTRNSIVMSSEDDIKWVCQDLDPGDCKEL
                     HNYMERLHENV"
     exon            766..1654
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1801
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     exon            1802..1985
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     exon            1986..2129
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2335
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     exon            2336..2609
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     exon            2610..2801
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     exon            2802..6135
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6114..6119
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /note="hexamer: TATAAA"
     polyA_site      6135
                     /gene="TMEM132D"
                     /gene_synonym="MOLT; PPP1R153"
                     /note="major polyA site"
ORIGIN      
        1 agtgcgctcg gcgcgcgtag agccccgcga gccccagccg ggcccggggc cgggcgggcc
       61 gaggcggcgg ccggggagca gccgcacccg ccaaactttg ggtgccggag cgcgcgcgcg
      121 cccgagcccc gaggcgcagc ggccggcctg ggatgggggc tgcgggccag ggagccccgg
      181 gccgcccagc gagcccggcc acccgcccgg ggggctccga gccgcctctg cccgcgtccc
      241 gggctccgca gccccgccac cccggcgccg cctgcgccag cgcccgctag ccagcccggg
      301 agcagctgga gccgccggag ccctgcgcct ggaggcgccc ctccttgggc caccgggggc
      361 cactcttcgc tcgggtaaac aggaaaggaa ataccccctg tggattaaaa tttaaaaaaa
      421 attctgttgg ggtcgaagga gggaggtggg gtttgcctgc gcgcgtgttg gactccggag
      481 agcaactcag gagcccgcgc ggtcgtcgcc tcccggcctg gccatggact ggcgggaaga
      541 gggagcaggg cgcccgggct gctcgggccc ctagccgggc gctccctcgc caccggcccc
      601 gctgcgggcc tctaggggac tgagacggtc tcttgttcgc ctggacggcg ccggggagcg
      661 gaggatctgc gctccgggtc tccaggatgt gcccgtctga gatggggacg ctgtggcacc
      721 actggtcgcc ggtactcatc agcctggccg ccctgttttc caaagtgacg gaaggtcgag
      781 ggatccttga gagcatccag aggttttcct tgctgcccac ctacctcccc gtgacctacc
      841 acatcaacaa cgcggacgtc tccttcttcc tgaaggaggc caaccaggat atcatgagga
      901 actccagcct gcagtcccgg gtggagtcat ttctgattta caaatccagg aggctgcctg
      961 tcctcaatgc cagctacggg cctttctcca tcgagcaagt ggtgccccag gatttaatgc
     1021 taccttccaa cccatttgga ttcaccaaca aattttctct taactggaaa ctaaaagccc
     1081 acatcctgcg ggacaaagtc tacctgagcc ggcccaaagt gcaggttctg ttccacatca
     1141 tgggcagaga ctgggacgac cgcagcgccg gggagaagct gccgtgcctg agggtctttg
     1201 ctttccgaga gacccgagag gtgcggggca gctgccggct gcagggggac ctggggctgt
     1261 gcgtggccga gctggagctc ctgtccagct ggttcagccc ccccacggtg gttgccggga
     1321 ggaggaagtc cgtggaccag ccggagggga cccccgtgga gctctactac accgtgcacc
     1381 cagggggtga gagaggggac tgcgtcaggg aagacgcgag gagaagcaat gggatccgga
     1441 caggccacag tgacatcgat gagtccgggc cccccttgca gaggatcggg agcatcttcc
     1501 tttatcagac acacaggaaa ccctccctga gagaactgcg tctggacaac agcgtggcca
     1561 tccactatat accaaagacc gtgaggaaag gagacgtgct gacttttcct gtttccatct
     1621 ccagaaattc cactgaagat cgcttcacgt tgagggcaaa ggtgaagaaa ggcgtgaaca
     1681 tcatcggcgt gcgagccagc agcccttcca tttgggatgt caaggagcgc acggattata
     1741 ctggaaagta tgcaccagct gtcatcgttt gtcagaagaa agcagctggc tcagaaaaca
     1801 gtgcggatgg cgcctcctac gaggtcatgc agatcgatgt ggaggtggaa gagcctggtg
     1861 acctgccagc cacacagctg gtcacgtggc aggtcgagta ccccggagag atcacgtctg
     1921 acttgggagt gtccaagatc tatgtgagcc caaaggactt gattggagtt gtgccgctgg
     1981 ctatggaggc agaaatcctg aacacagcca tcctcacggg gaagacggtg gccgtcccgg
     2041 tgaaagtggt ctccgtggag gacgacggca cagtgacaga gctgctggag tctgtggagt
     2101 gtagatcgtc tgatgaagac gtgattaagg tttctgacag atgtgactac gtctttgtca
     2161 atgggaaaga aatgaaaggc aaggtcaacg tggtggtgaa cttcacctac cagcacctga
     2221 gcagccccct ggagatgacg gtgtgggtgc cccggcttcc gctgcagatc gaggtctccg
     2281 acaccgagct caatcagatc aagggttgga gagtgcccat cgtctccagc aggaggcctg
     2341 ccggggacag tgaagaggag gaggatgatg agcggagggg ccgcggctgc accctgcagt
     2401 accagcacgc catggtgcgg gtcctgacgc agtttgtggc tgaggcggcc ggccctgggg
     2461 gacacctggc ccacctgctg ggctcagact ggcaagtgga catcacggag ctgataaatg
     2521 acttcatgca ggtggaggag cccaggatcg ccaagctgca aggcggacag atcctgatgg
     2581 ggcaggagct tgggatgacc accattcaga tcctgtctcc tctgtcagac accatcctcg
     2641 ctgaaaagac catcactgtg ctggacgaga aggtgaccat cacagacctc ggggtgcagc
     2701 tggtgacagg gctgtcactc tccttgcagc tcagcccagg aagcaacagg gccatctttg
     2761 ccactgcagt ggctcaggaa cttctgcaga ggccaaaaca ggaagcagcc atcagttgct
     2821 gggtccagtt cagtgatggc tcagtcacgc ccttggatat ttacgatggg aaagacttct
     2881 ccttgatggc cacatctttg gatgagaagg tagtctccat ccaccaagac cccaaattca
     2941 agtggcctat cattgctgcg gaaacagaag gacaaggcac cctggtcaag gtggaaatgg
     3001 ttattagtga atcctgccag aaatccaagc ggaagagtgt gttagctgtt ggaacggcaa
     3061 acatcaaagt taaatttggc caaaacgatg ctaaccccaa caccagtgac agcagacaca
     3121 caggggcagg ggttcacatg gaaaacaatg tcagtgacag aaggcccaaa aaaccctcgc
     3181 aggaatgggg gagtcaggaa ggacagtact atggcagttc ttctatggga ctcatggagg
     3241 gacggggcac cacgacagac aggtccatcc tgcagaagaa gaaaggccag gaaagccttt
     3301 tagatgacaa cagccacttg cagaccatcc ccagcgacct caccagcttc ccagcccagg
     3361 tggacctccc cagaagcaat ggggaaatgg atgggaatga ccttatgcag gcatccaaag
     3421 ggctgagcga cttagaaatt gggatgtatg ctttgttggg agtcttctgt ttggccattt
     3481 tggtcttctt gataaactgt gtgacctttg cattaaaata cagacacaaa caggttccct
     3541 tcgaggagca ggaagggatg agtcactctc atgactgggt tgggttaagc aaccggacag
     3601 agctgttgga gaatcacatc aactttgcct cctcgcaaga tgagcaaatc actgccattg
     3661 acaggggcat ggatttcgag gaaagtaaat atctcctcag cacaaactcc caaaaaagca
     3721 tcaatgggca gctgttcaaa cctttgggac ccatcatcat tgatgggaaa gatcagaaaa
     3781 gtgagccccc aacatcccct acctcaaaaa ggaaaagggt aaaatttacc accttcaccg
     3841 ccgtctcctc agacgacgag taccccacca ggaactccat cgtgatgagt agcgaggatg
     3901 acattaagtg ggtctgccag gatctggacc ctggggactg caaagagctg cacaactaca
     3961 tggagaggtt acatgaaaat gtgtaagcca gacacacaca gacattggtt ctcactcacc
     4021 tttcagcctt taattccagg atgtgtagca acggtgcccc cggaagagaa acaaagcagc
     4081 aggacaaaat aaggatgaca ctatccatac agcctcagcc aatgaccccg gctcggcggc
     4141 gaggcctgga gtccgcatcg acgcacacat tccagagtac agtgtcttgc ttaagaggtt
     4201 tatcatgcat ggcaagattt ttaagacttg aaacaaaaac gagttctgaa tcactgagcg
     4261 tctgagagcg tccaggaaag aacagcctct ctctctcgaa tcaaagcaat ttggatattg
     4321 taaaatccac atggctccaa tattcaatat tgcagactat ggaagaaaag tacaactcag
     4381 gtggagcatc catggatcgc atccatggat caatgggagg aagcgtgtca tcgaaactgg
     4441 agcagcacat cttgctgtga gcgcgatcac aggcagtcca gtgccgccgt cagctgtggg
     4501 aggcatgatt gtgagtcatt gtctctcaaa ggctgggcca gagctgtctc agatcatgga
     4561 caggccaagg aagtggctga caaggactga aagggaacat gtgggctaac aggccacaaa
     4621 tacctttgta actacatgcc aaggacaaac acatggacgc aaatcctctg agcccttcag
     4681 ggtacttctt tatttgtaaa ctaaggatac tgggcataga atttgaatca ggttcaaaga
     4741 accacgctct tttgattcat atcaagttca caatgtatcc atttctattc ctccactgca
     4801 ttgccatcct ccccaaagcc gttggtcacc tgtgggtggg ggagggagag ggcagtttgt
     4861 agtatttgct gggtcttttt tctccccctg ggttttgtgt caactcccaa gtgacattct
     4921 gtagagaagc tccccccgca acctgggcat atgtcccacg ccgtccgtct ttgaagaggc
     4981 tggtctctag gcatgggcgg tagtcacggt gaattccata ccaggggata tacattccct
     5041 tgctttacta gaaagaaaac agggccactt gggatgggtc tttcactgtt catggcagat
     5101 ctcctgtcca aagatgtggc ctcgaggctg ttgagacaaa tcggggtgcc tgtgtggaac
     5161 gtgcagggcg tgtggagttg ggggggttct gggtgtgaaa gtggtggatc cagcaggaag
     5221 cccagcctca cacacaccgg acagcacaga aaccttcttc atcttggagg tgcgaaggga
     5281 taaggggcat cagtgcatgt ggtgaagatg caggtttgca agcacttggt cctgcagtca
     5341 gccccgaaag gttcagcatt gcttaagacc agccatgact ctggatatcc ctgaatccct
     5401 tcacttatga agcctatgaa gatgggggca aggatacatc agagaattcc tgcctcatct
     5461 cacgctcact ccaaggtaga gaatggtgtg ttgggtgatt gccagccaga taggatcctg
     5521 caaaagatgg tcgggggcag cgggtggtgg gcagaagagg ccgtgctgtt gaattgatct
     5581 tctatttttc cctctggtca ttttctctct ctctctgctc ttcagttgtc tgttttccag
     5641 tctctctgtg tgtctgtctc tgtatctctc tcctcctttg aacctatctt ctccctgctt
     5701 cctctccatc tcatctctgt aattttgagt gtgtgtcttt actccttctt cctctccata
     5761 gaattgaatt ctctttagat catgtgtgtg taaatttcac cagtttaccc tcccaacctt
     5821 agccctctcc cctgcaactg tggtgctctt gagactgagg tttctgcagc cagtaagtca
     5881 cctgctcctg tccgcaagct tacctacctt gtttggttgg gtgattaagc tgtcacccct
     5941 tttcaatgag aatcctttgc tttcagtaac gtcctcatat ttctttccat tcttacctgt
     6001 gtcatgttct gttgaatact gcagccgctg cccgcttcca aatccatctg cgtgtagaat
     6061 gtactgtaga ttgtaagaat gtaatatata tttataaact tactgactgt aaatataaag
     6121 tttgcattca gtggc
//
