LOCUS       NM_001366854           11325 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens transmembrane protein 132B (TMEM132B), transcript
            variant 3, mRNA.
ACCESSION   NM_001366854 XM_011537852
VERSION     NM_001366854.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 11325)
  AUTHORS   Sanchez-Pulido,L. and Ponting,C.P.
  TITLE     TMEM132: an ancient architecture of cohesin and immunoglobulin
            domains define a new family of neural adhesion molecules
  JOURNAL   Bioinformatics 34 (5), 721-724 (2018)
   PUBMED   29088312
REFERENCE   2  (bases 1 to 11325)
  AUTHORS   Farlow,J.L., Lin,H., Sauerbeck,L., Lai,D., Koller,D.L., Pugh,E.,
            Hetrick,K., Ling,H., Kleinloog,R., van der Vlies,P., Deelen,P.,
            Swertz,M.A., Verweij,B.H., Regli,L., Rinkel,G.J., Ruigrok,Y.M.,
            Doheny,K., Liu,Y., Broderick,J. and Foroud,T.
  CONSRTM   FIA Study Investigators
  TITLE     Lessons learned from whole exome sequencing in multiplex families
            affected by a complex genetic disorder, intracranial aneurysm
  JOURNAL   PLoS One 10 (3), e0121104 (2015)
   PUBMED   25803036
  REMARK    GeneRIF: TMEM132B is differentially expressed in intracranial
            aneurysm samples as compared to controls.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 11325)
  AUTHORS   Winham,S.J., Cuellar-Barboza,A.B., Oliveros,A., McElroy,S.L.,
            Crow,S., Colby,C., Choi,D.S., Chauhan,M., Frye,M. and
            Biernacka,J.M.
  TITLE     Genome-wide association study of bipolar disorder accounting for
            effect of body mass index identifies a new risk allele in TCF7L2
  JOURNAL   Mol Psychiatry 19 (9), 1010-1016 (2014)
   PUBMED   24322204
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093028.13, AC026370.31, AC004806.2 and AC005146.1.
            
            On Oct 24, 2018 this sequence version replaced XM_011537852.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.90461.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144120, SAMEA2145240
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000682704.1/ ENSP00000507790.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-481               AC093028.13        4592-5072
            482-1373            AC026370.31        72808-73699         c
            1374-1520           AC026370.31        7474-7620           c
            1521-1707           AC004806.2         123454-123640       c
            1708-1851           AC004806.2         59085-59228         c
            1852-2057           AC005146.1         2999-3204
            2058-2328           AC005146.1         9606-9876
            2329-2520           AC005146.1         11364-11555
            2521-11325          AC005146.1         12488-21292
FEATURES             Location/Qualifiers
     source          1..11325
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q24.31-q24.32"
     gene            1..11325
                     /gene="TMEM132B"
                     /note="transmembrane protein 132B"
                     /db_xref="GeneID:114795"
                     /db_xref="HGNC:HGNC:29397"
                     /db_xref="MIM:620260"
     exon            1..481
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     CDS             415..3666
                     /gene="TMEM132B"
                     /note="isoform 3 precursor is encoded by transcript
                     variant 3"
                     /codon_start=1
                     /product="transmembrane protein 132B isoform 3 precursor"
                     /protein_id="NP_001353783.1"
                     /db_xref="CCDS:CCDS91772.1"
                     /db_xref="GeneID:114795"
                     /db_xref="HGNC:HGNC:29397"
                     /db_xref="MIM:620260"
                     /translation="MPPPGRAPPLGLLLALTALQCPVTESRGIVDSLQKFSSLPAYLP
                     TNLHISNAEESFFLKEANQDLTRNSSLQARVEPFFIYRARTPPIINASYGPFSVEKII
                     PQELLLTSTAFGNMDKFPFNWKLKSHILDSSIYSNRPKVQTLFYVTGMGWDDSDLTED
                     LPCVKMFAFPEAREVAASCRLQGAPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGT
                     TMELFFTLYPADKAGQCPLEEEGKWENNIHSGLESPQQAFPARERIGSVVVYPTQDDL
                     KWSLVSLDENVVISVPLNLVREGDTATFLVSLTSSSVADQFTLRIKAAAGVKITAVRV
                     SSEDQWAVQEEIDNGSTQTSATLTCMGHRPDTQSRVNGSFYEILQVDFGIDNSSDLAG
                     AQQITWQVEYPIEDSMSELVVSEIFVSQTTFVGIVPLAMDTEVLNTAILTGKPVSVPV
                     KVVGVQEDGSVVDVSESVECKSADEDVIKVSNNCDSIFVNGKEMKSKVDTIVNFTHQH
                     FTSQFEVTVWAPRLPLQIEISDTELSQIKGWRIPVAANRRPTRESDDEDDEEKKGRGC
                     SLQYQHATVRVLTQFVAESPDLGQLTYMLGPDWQFDITDLVTEFMKVEEPKIAQLQDG
                     RTLAGREPGITTVQVLSPLSDSILAEKTVIVLDDRVTIAELGVQLVAGMSLSLQPHRA
                     DKRAIVSTAAALDVLQSPQQEAIVSSWILFSDGSVTPLDIYDPKDYSVTVSSLDEMVV
                     SVQANLESKWPIVVAEGEGQGPLIKLEMMISEPCQKTKRKSVLAVGKGNVKVKFEPSS
                     DEHQGGSNDIEGINREYKDHLSNSIEREGNQERAVQEWFHRGTPVGQEESTNKSTTPQ
                     SPMEGKNKLLKSGGPDAFTSFPTQGKSPDPNNPSDLTVTSRGLTDLEIGMYALLCVFC
                     LAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNEVELLENPVDITLPSEE
                     CTTMIDRGLQFEERNFLLNGSSQKTFHSQLLRPSDYVYEKEIKNEPMNSSGPKRKRVK
                     FTSYTTILPEDGGPYTNSILFDSDDNIKWVCQDMGLGDSQDFRDYMESLQDQM"
     exon            482..1373
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1520
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1707
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     exon            1708..1851
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     exon            1852..2057
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2328
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     exon            2329..2520
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     exon            2521..11325
                     /gene="TMEM132B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7981..7986
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM132B"
                     /note="hexamer: AATAAA"
     polyA_site      7999
                     /gene="TMEM132B"
                     /note="major polyA site"
     polyA_site      11300
                     /gene="TMEM132B"
     regulatory      11307..11312
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMEM132B"
                     /note="hexamer: AATAAA"
     polyA_site      11325
                     /gene="TMEM132B"
ORIGIN      
        1 actctctcgc tggctcgagg ggcggccggc agatggcgat ggcagaggcg gcggcggcgg
       61 cggcggcgcg accgggatgg gacgggcgct ggggcgcagg agccgcggcg gcggcggcgg
      121 cgggggccgc gcaactcggg ccaactgcgg ggcagccggc cagggcgcgg ggcgctgagc
      181 ctcggccgcc ccagctcccc agccacgcac ggccgagccc aggagagcgc gcagaggcgc
      241 agccgaggaa gcgccgccag cgccggcgca tgcgtctggg gaggagcggc gcgctgggag
      301 cgagccatgc ccggcgcccg ggcgtagccg ccgggggctg ctccgggagc cgcgggccgg
      361 gccgggcgcg cgagaggagc agccccgcgc cgcacccacc gcgcgccgag gaccatgccg
      421 cccccgggcc gggcgccgcc gctcgggctc ctgctggcgc tgactgcgct ccagtgccca
      481 gtgacagaga gtcgagggat tgtggatagc ctgcagaagt tttcctcgct ccctgcttac
      541 ctccccacga acttgcacat ctccaatgca gaggagtcct ttttccttaa agaagccaac
      601 caagacctca caaggaactc cagtctgcag gcccgggtgg agccattctt catctaccga
      661 gccaggacac cccctattat caatgccagc tatggcccat tttcagtgga gaagataatc
      721 ccccaggagc tcctgttgac atctacagcc tttggaaaca tggacaaatt tcccttcaac
      781 tggaaattga aatcccacat ccttgacagc tccatctact ccaacagacc caaagtgcag
      841 accttgtttt atgtcactgg catgggctgg gatgacagtg accttacgga agatctaccc
      901 tgtgtcaaga tgtttgcttt ccctgaggcc agggaagtgg cagccagctg tcggctgcaa
      961 ggggccccag ggctgtgtgt ggctgagctg gagctgctgc ccgagtggtt cagctcaggc
     1021 ctggacctgg aaccagagga ggagatccca gccctgctcg ggggcaccac gatggagctc
     1081 ttcttcacgc tctacccagc tgacaaggct ggccagtgtc ctctggagga ggaaggcaag
     1141 tgggagaaca atatccactc gggcctggag agcccccagc aagcgtttcc agcccgagag
     1201 aggattggga gtgtggtggt ctacccaacc caagatgatc tgaagtggtc cctggtgagc
     1261 ttggacgaga atgtggtcat ctcggtacct ctgaatctag tccgggaagg ggacacggcc
     1321 acctttttgg tctctctgac cagtagctct gtggcagacc agttcactct tagaattaag
     1381 gcggcagcag gtgtgaagat aacggcagtg agagtcagca gtgaggacca atgggcagtc
     1441 caggaggaaa ttgataatgg cagcactcag acgtcggcca ccctcacctg catgggccat
     1501 cgcccggaca cgcagagcag ggtaaatgga tccttctatg agatcttgca agtggacttt
     1561 ggaattgata atagcagtga cctggctggg gcccagcaga ttacctggca ggtggagtac
     1621 ccgattgagg actccatgag tgagctggtc gtctccgaga tcttcgtcag ccagacaacc
     1681 ttcgtgggca tcgtccctct tgccatggac accgaggttt tgaacactgc cattctcact
     1741 ggaaagcctg tttcagttcc tgtcaaagtc gtgggggtcc aggaggatgg ttctgtggtc
     1801 gatgtgtctg agtctgtgga atgcaagtct gccgatgaag atgtcattaa ggtttccaac
     1861 aactgtgatt ccatttttgt gaatgggaag gaaatgaaga gcaaagtgga cacgattgtg
     1921 aacttcaccc accagcactt cacctcccag ttcgaggtca ctgtctgggc acccaggctc
     1981 cccctgcaga ttgagatctc agacaccgag ctgagccaga tcaagggctg gaggatcccg
     2041 gttgctgcca acagaaggcc tacccgggaa agcgatgacg aggacgatga ggagaagaag
     2101 ggacgaggct gctccctgca gtaccagcac gccacagtgc gtgtcctcac ccagtttgtg
     2161 gccgagtcac ctgacttagg gcagctgacc tacatgctgg gccccgactg gcagtttgac
     2221 atcactgacc ttgtgaccga gttcatgaag gtggaggagc cgaaaatcgc tcagttacag
     2281 gacggcagga ccctggctgg tcgggagccg ggaataacca cggtgcaggt cctctcgccg
     2341 ttgtctgact ccatcctggc tgagaagacg gtgattgtcc tggatgaccg agtcaccatc
     2401 gcggagctgg gagtgcagct cgtagctggc atgtctctct ccctgcagcc acaccgagca
     2461 gacaaaaggg ccatcgtctc cacagctgct gccctggatg ttcttcagtc cccacagcag
     2521 gaagcaatag taagttcttg gattttgttc agtgatggtt cggtgacacc tttagacatt
     2581 tacgatccta aggattattc tgttactgtc tcatcattgg atgaaatggt ggtgtctgtc
     2641 caggcaaacc ttgagtccaa atggccaatt gtggttgcag agggtgaagg acaagggcct
     2701 ttgattaagt tagaaatgat gataagtgaa ccttgtcaga agaccaagag gaagagtgtt
     2761 cttgccgtgg gtaaaggaaa tgtcaaggtc aaattcgaac caagtagtga tgagcaccaa
     2821 ggaggcagca atgatattga gggcataaat cgggaatata aagaccacct cagtaattcc
     2881 atagagcgcg aaggaaacca ggagagagca gtccaggaat ggttccaccg tggcacacct
     2941 gttggccaag aggaaagtac caacaaaagc acaacccccc agtctcccat ggaagggaag
     3001 aataagttac tcaaaagtgg tggtccagat gcctttacaa gcttccccac tcaagggaag
     3061 tcaccggacc ccaataatcc tagtgacctc acagtgacct caagggggct aacggacttg
     3121 gagattggca tgtatgcctt gctctgcgtc ttctgtctgg ccattctggt cttcttgatc
     3181 aactgcgtgg cgtttgcctg gaaatacaga cacaaaaggt ttgctgtgag tgagcagggc
     3241 aacatccccc attcccacga ctgggtctgg cttgggaatg aagtggaact tttggagaac
     3301 cctgttgaca ttacactccc atcagaggag tgcacaacca tgatagacag gggcctgcag
     3361 ttcgaggaga ggaacttcct tctgaatggc agttcccaga agacttttca tagtcaacta
     3421 ctcagaccct ctgactatgt ctatgagaaa gaaattaaaa atgaacctat gaattcttcg
     3481 ggcccaaaga ggaagagagt caagttcact tcctacacca ccatcctccc agaggacggc
     3541 ggcccataca ccaactccat cctgtttgac agcgatgata acatcaagtg ggtctgccaa
     3601 gatatggggc tgggggattc acaggacttt agagactata tggaaagtct gcaagaccag
     3661 atgtaaactc ctttcttatg tttgtattca cctttatgcc ttctgttttt tgaatgctgg
     3721 agcagtgagt ttgatcagca ataggggatg atttaacaaa gtttgatttg tggaggtctg
     3781 gtgggattca tttctaagca ggtaaaagag gtttggagag ctatagaagc tgggttttaa
     3841 gtttggaaat gcctctaaaa cagccacatg tggggactgg agaaattcta agacaacagt
     3901 tttatggact gcctggtacg agctcagtgc aaatgtatta aacctgaccc cacagacatt
     3961 gttagtcatc tcgtgacaaa tggccatgtg gaattagaaa agatttgggt gttgattttt
     4021 ctatttctag accttttaaa gcacagtgga cacttattgc cccttggcct gagtttagac
     4081 atacatgaaa gatgactgaa tgtagctatc ctgatttgtc atgagcgctg ctcattattt
     4141 ttatatacat ttgcacctgc acctgttcct ttgacctctg gaattctttt tgaaacatga
     4201 agagaagaaa tttcagtctt ttccttgagc tctgtttgat ttacacatga gttttcttcc
     4261 ctgggatttg ccatgccatg ttatttcctg ggtctccatg caggatgtca ggtttttcca
     4321 gttttctgca cttcatcatc tagggatggt atccaagaag cttattctca ctttgttttt
     4381 tccttccttt tgttgttgaa ctttcttgta taacactggg acaaagggtt ttacttaaaa
     4441 tgttaatata cagtgaggga gggccatctc tttactgttt tctatgtgaa gtttcaaaca
     4501 tttggaaaaa agttgtcaat cacaaacatt tatttttatt ctctgcttgt tgaaaactca
     4561 tggggaactc ctggagtgca tttctgaggg taaaaaggcc ccaacatagc tgtatttata
     4621 caagtgcttt gtggccaaca caatttacta tccaaactga agtcttaaag tagaattgac
     4681 ctacacagaa aggaaattgc ctaggcaata gatgcagatt acactttcca ttttaccaga
     4741 acaaaagttt tttttttttt aaataagtag aatgacagtt caagttagca atatatagaa
     4801 atccatccat acaatgacca aaataaataa ataaataaaa ctcaatcatg actttggcag
     4861 agataaaaca ttgacaaggg tgtgcatttg tggagagaag cagtgggttt ccccccaaaa
     4921 tccatacaaa taaatgacta ttccagaact caagaagcag ctattataga aaaaaaaatt
     4981 aaaaaccaca gctattgaaa aattaaaacg gcaagagaaa aaaagaaaca actcctgcat
     5041 aatgtttaaa taaaaatgtt attttaatag catcatgaat ggtcttaagg caaaaatttc
     5101 agattagcaa aatgtgatga catatttatt aagattgtat tattggaaat gtagacactg
     5161 gactagtatg cctcattatg agctttactg agccatttgc atctctaaga aatatgattt
     5221 taaaggccca aagtaggaag gatctgcagg gggtcacctg aagcagtgcc ctgactccaa
     5281 atggctgata actgagctaa tccaaggaga ggcgttcagt tgttctctta ttatagattt
     5341 ccttgggtgg gaacatgaca accccgcctc ctctagccat gacgtggcag ccaaaaagtt
     5401 cttcctgtat ctctggccca caggactgta gtgtgtttgg gaacagtgct gaaattgcaa
     5461 gtgatgtagg cctgacctcc agagcccagc gttcagttag ttgtataaaa tggggcttag
     5521 gaaccgaagc tgatgaagtt ccaaaagtag ttcagtttga tgggataagg aagcaaggag
     5581 agccaggcat tagctgcaaa aggagcttgc agagagatgg ctgacacttt atgggaagat
     5641 tcctcagtca gccaaaagct tttcaaagag tttggtgcag aggtagctca gagccaacca
     5701 tccaggaccg aagaaagctc atgtgctgat tgacacatag ctatccaggt gagtcggctc
     5761 cttctatgag gcttttcaat cgtctctccc tttggatctc tggcattcca gaaagactgg
     5821 gaattcattt ctgaaaatga tgaacctccg ctgaaacggg gaggaaatct cttacacaca
     5881 tacagcaggg tcctgcccac tggtaaagtg agacgttggg tagggggtgt aactggggag
     5941 gaggtgaagg aaattatccc tgccatgggg agtgttattc aggaacataa aaattagagc
     6001 attccctctg atggcagtgc ttgacggggt gcagggaaca aactggggag cgttcaaaca
     6061 tgccagtggt ttctcagcag ggctggaaac tggccacagt cctgaagatg cttcttgtga
     6121 caacttagag tcactgggag tcacacagct cctgtgtagc cgcctttgct cctctgtgtt
     6181 aaaacccagt cagttcaaaa taacaatcaa atggaaggcc atgggggaag ggttccttcc
     6241 accatataac ccacacccag atgtatataa acgcatatac atacatatac ccgtgtgtgt
     6301 gtgtgtgtgt gtgtgtgtgt gtgtgaatac tgaagagcca gacaacaaac tatttagtaa
     6361 gaatcaacag tgactgtcaa ttgttctcag atttggcatg gatactattt ctcatgaaat
     6421 aatgtcatta aagtatttcc tcctctaaat atttcctgaa gatcataaac catgggttat
     6481 agcaccttgt tttccagcta gtcaatatac aactattagg tgctgtgccc caaaatatct
     6541 aaaatggggg taaagatata aactattaag ccatgaaatc taattttctg gggaccatgc
     6601 atttgcctgg attttccagg attttatggc tgatagaccc aaattattag tcttgataaa
     6661 caacctgaac caaacattta taaagtccct tcctctccca tgggaatgga atgctcagac
     6721 tcctgctgag ggagacacca gcaagcctct tgagaaggca ccagacagtg aactctgtgg
     6781 tcacatgaag ggaggttcag atgctagacg accagcgtat gacctggaac cattgaggat
     6841 tgcaaccgct gcctccaggg tccagatgtg ctgcagtaga gggcagagca caggaatcaa
     6901 gaagcagctg ccacaccaaa gaactgatgc ttaaacacac aggtgtgttg catttgagag
     6961 aaggcaagaa gaaaagacaa tagaaggtta ccctggaaaa acaacaccta gcaaacctca
     7021 gaatactcca tgtgtcccaa gagaaggaat aattgtcttt ctagctgtta tatattgcac
     7081 actggccagg ataaattccc agactataat aatcctgact atgtagacgg aagtttctat
     7141 ttataaagtc atgcaggggg aaagttgatt aatttttgtc ccattgccac atctgtagac
     7201 taagtaattt ttaacttgct aacttttaga atgtccacct ttgtgcattt tggtagcatt
     7261 cttgtttcat tattttagaa aggggtcttc ccattactgg gatgtcgggg ccctgtcaga
     7321 gaactattat taaggctctg tgagggaact gttcagtctc acagcaagga ccacagagcg
     7381 tggtttcatc tgaaccctac aagtcaggga caccagtgtg ttttctactc gagttaccta
     7441 aaaatggtct caattttcca tttcattctc tgtaaatgac acaatagatg gtttatagac
     7501 tcagcagccc tcacctttta ttaaaattat atatgtgtga tgtaatgcat atcacctgtc
     7561 atgtaaaggg acggtatgga tggtggaaaa gttatgctaa aatatggatt gcagatattt
     7621 ttgtatgtaa tataggcaat ataatgaaac accgagtttt ttaaagtgaa agcatgcaaa
     7681 atcgtagctt ttaaatgtac agacatccca ctcaaaaata tctaaactga tagtgggaaa
     7741 aacatttgag acctagtaac atcatgaaat gcactgaatt tggaattctg gcctagaaag
     7801 gctgtggctt atgttgggat tgatgatgga atctgccaga acattttcat cttattcttc
     7861 ttgacttttg gatttttttc ttttcttttt ttctggaaat atttcggaaa taaagtgact
     7921 tcatttttca gcataaaagt atattctaac cacagggtaa cacatcgttt ttaacatgaa
     7981 aataaacatt taaacattct tcagttgttt cattatttta tctgcatgtt ccataaagca
     8041 gctgtatggt tggctataat atagatttat tttttctttt cagccagaga ttttaatacc
     8101 cttgatgcag taataaatgg acatcaaaag aaaacatttc ttaaaagttg ccaacgtatt
     8161 ttaccttgaa aacatttctt atttgttatc ctagtaggct ggggaaagct tctctccaga
     8221 tgtctcagaa aaagatctcc tgtttctcat ggccccgtcc agggtcaaac catgttgaaa
     8281 gtcagtgctg aaatgcatga tgctgcgggt gtttgagagc ctttgacctc tgtccaccct
     8341 ttggtctttg ctcgtcaatg gcttggtctt gtatatgtat ctggggcagg ggctttgtac
     8401 tgggcccagg gtgctgagct ttccagaaca ggcagagctc tagagaccta agaaaaccac
     8461 aggacaggcg gggattcttt ttgagaggct gaagtagatg tttcagctga aagatgggtg
     8521 gtacacttgc caagtgccta gaggggctag aggctctctg ttggtgtgtg tgtatttctt
     8581 gaaactgcag agtcattttt ggcatgctgg caaatgctac tccttgcttt taggatgaat
     8641 agggatgcct ctttggcgat aatttgacgt gtcataataa atgcccaata ccaaacctag
     8701 tctttctcca ggcccttcag acatcattca ggtaactggg tgtaaacaca ggagttggct
     8761 ttgtgaaact gaggcaggat ttcctgcctc taaactattg gcagcaaaag agccaaaaat
     8821 gtgctcccag gtgcaaaacc ccagccccat cagaattgct tctcagcact ttgggtaact
     8881 gttttgcact aacagcttcc tccttgtctt ttccctggga acatgggagc actgacacag
     8941 aactcaactg gtccagccct ttgggaggcc caggtgggca gatcacctga agtcaggagt
     9001 ttgagaccag cctgggcaac atggtgaaac cctgtctcta ctaaaaatac aaaaattatc
     9061 cagtcgtggt ggtgcatgcc tgtagtccca gctactctgg aggctgaggc aggagaatca
     9121 cttgaacctg agaggtgaag gttgtagtga gccaagatcg taccactgca ctctggcctg
     9181 ggcaacaaga gcgagacttt gtctcaaaca gaaacaaaac aagaaaaaca aaaagaactt
     9241 aaccagttct ccccagatct cagcgtgcat gcatatatag agtttagtaa aatgtgtttc
     9301 aaaaaaagaa ggataaaaga aagtttgaag taagatttgt aaaagaatga acactttagg
     9361 ttttgtgtgt gagtgcaaaa tgtaaacacg gcatttgaaa ttttttggta ttgaaatcct
     9421 taatgcctgt tagtttcttt atggttttat acaattgaga taggttctga agtttttttg
     9481 ttgtttgctt ttagaaattt ttaaaaatac aaaaaaaaag cgcagaaaca ttttcatctg
     9541 ggttactgtg tttatagact attctatgac tcaagacaac taggacacca tcattttcca
     9601 gataagaaat aacagttcaa gttcattagg gaaattatct tcccagtcca agcaagcaat
     9661 aatgttatca acttacaata ttggacaatc ttcatattct atgagatgcc tttaaaattt
     9721 ctttggattt aatgctgctc ttggtcagtt gttcaaatga aacattgtaa tttcatgtta
     9781 acgacaagag tctcacggga gtctctttag atgctgcagg aactgagagg atagaagacc
     9841 tctctataca tctacattgc ccattggagt aaagcacttt acagagagat ggatgccgct
     9901 ttgggatttg gggtctatgt aatgctgatt tttttcaaac ctgtttggaa atattacttc
     9961 tttgggatgg ctgaaataac ttttgacctg acacatcttt ctgtacttcc tgtggccaaa
    10021 aaagcaagtg agactttctg tttcccattg taaggctgga gctgaaatag tctgccacgt
    10081 tattgttatc tcctttgtaa gaatttgact ttctgaatga aataacagaa tgccagtgtc
    10141 aacactgacc atatgatata gttatttcac ttagagatgc ttcctcaaag agcgtgcctt
    10201 tttcctccat cataaccgct ttaggatctc tgttttatcc atgtatttcc cacatagtag
    10261 aagcattttc catttccatg aatattacag gctgagaagg agcacacatc tggcactgat
    10321 aagcacactg gcccaggcac tcagccttct catttcatta atctggttgg tgaccgtttc
    10381 catcgggcac acctggaaat gtccatcgga catattgcca tctcagttgc tgcagtgcag
    10441 tgaattaccc cagagccacc agttcacatg cccaaagatg aactggccca tggagggact
    10501 tgattgccaa gtgacttcct ttctgtagtt atcctctgct gtgaccctta ttttggactt
    10561 ctagcaaggg cattcagtgt ggattccaag aacaaaacca attgtccaac ctccattaca
    10621 ggggtcttct aggtattccc cacacattat ttgtgggcat aagcaaacac cataactatg
    10681 aaaggctgag agtggagaat taagtcataa ggaaatgatc aaacctaggg aaaaataagt
    10741 ggctataaaa cactgaaaga tagtcacatc cacatagcgt gtatcatgca acagacccgt
    10801 gctcttagag ggaggtagtg tgtgtcttcc catggcaaat aatttttaca atactgctca
    10861 tgtttaatgt gtgtctacag ggcatgctgt tgtctcaaaa ttgaaatgtg catcttaggt
    10921 atcagttccc agcctcagac tcttctcagg caggtggacc ggatctcagc tgcagaacat
    10981 agtgagtggc caaacctaca cagcccagcc agtagtgtgc tttggggtga ttgcaaggca
    11041 gcaaacagtg gggacaagtt ttgtctggca tttgaaaagg tgttatccct tactttccac
    11101 atttctgaat tggattcttg ttccctggta aacaccagat attataaaca gagcatgctg
    11161 ttatgacatt gtgcttctat ataccttttt gtataatgta tctatctcat tatattacct
    11221 atggtttcag tatgatctgt tgtgtatgtt ccaccgtata tttaatgtct ctgtaaaggc
    11281 acttccaaac attttgaaaa cgaagaaata aaacatgttg gatga
//
