LOCUS       XM_047435255            7188 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transmembrane channel like 6 (TMC6),
            transcript variant X6, mRNA.
ACCESSION   XM_047435255
VERSION     XM_047435255.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7188
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..7188
                     /gene="TMC6"
                     /gene_synonym="EV1; EVER1; EVIN1; LAK-4P; lnc; TNRC6C-AS1"
                     /note="transmembrane channel like 6; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 8
                     mRNAs, 156 ESTs, 785 long SRA reads, 6 Proteins, and 95%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:11322"
                     /db_xref="HGNC:HGNC:18021"
                     /db_xref="MIM:605828"
     CDS             230..2647
                     /gene="TMC6"
                     /gene_synonym="EV1; EVER1; EVIN1; LAK-4P; lnc; TNRC6C-AS1"
                     /codon_start=1
                     /product="transmembrane channel-like protein 6 isoform X1"
                     /protein_id="XP_047291211.1"
                     /db_xref="GeneID:11322"
                     /db_xref="HGNC:HGNC:18021"
                     /db_xref="MIM:605828"
                     /translation="MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQC
                     TAQEGLELQQREREVTGSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQYY
                     NRTVQLRCRSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEEKQSLLVKELQSLAVAQ
                     RDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGL
                     ALLSALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVA
                     FPPALPGPAPVCTGLELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGG
                     LPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAITVFCSWDYKVT
                     QKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALGCAV
                     AVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVYV
                     AICRNLILKLAILGTLCYHWLGRRVGVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLF
                     GELVWRIISEKKLKRRRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLV
                     FYVKKTSLLANCQAPRRPWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCG
                     PFRTLDTMYEAGRVWVRHLEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNI
                     QVVRGQRKVICLLKEQISNEGEDKIFLINKLHSIYERKEREERSRVGTTEEAAAPPAL
                     LTDEQDA"
ORIGIN      
        1 tcagcaggtt gagtagcagc aggaagcgga ggaaggtgaa gtaggaccga attcctgtgc
       61 cgaagaggcc tgcagtggga gagcagggaa tgggtggtgt ggacagctgc caggcgttga
      121 agaccacccc tggctctgtg cccctgtctc atcagatggg ggctccggag gtggcgccca
      181 ggctctgagc taccctaggt ctgcagacta gcgggcattg gccagagaca tggcccagcc
      241 actggccttc atcctcgatg tccctgagac cccaggggac cagggccagg gccccagccc
      301 ctatgatgaa agcgaagtgc acgactcctt ccagcagctc atccaggagc agagccagtg
      361 cacggcccag gaggggctgg agctgcagca gagagagcgg gaggtgacag gaagtagcca
      421 gcagacactc tggcggcccg agggcaccca gagcacggcc acactccgca tcctggccag
      481 catgcccagc cgcaccattg gccgcagccg aggtgccatc atctcccagt actacaaccg
      541 cacggtgcag cttcggtgca ggagcagccg gcccctgctc gggaactttg tccgctccgc
      601 ctggcccagc ctccgcctgt acgacctgga gctggacccc acggccctgg aggaggagga
      661 gaagcagagc ctcctggtga aggagctcca gagcctggca gtggcacagc gggaccacat
      721 gcttcgcggg atgcccttaa gcctggctga gaaacgcagc ctgcgagaga agagcaggac
      781 cccgaggggg aagtggaggg gccagccggg cagcggcggg gtctgctcct gctgtggccg
      841 gctcagatat gcctgcgtgc tggccttgca cagcctgggc ctggcgctgc tctccgccct
      901 gcaggccctg atgccgtggc gctacgccct gaagcgcatc gggggccagt tcggctccag
      961 cgtgctctcc tacttcctct ttctcaagac cctgctggct ttcaatgccc tcctgctgct
     1021 gctgctggtg gccttcatca tgggccctca ggtcgccttc ccacccgccc tgccgggccc
     1081 tgcccccgtc tgcacaggcc tggagctcct cacaggcgcg ggttgcttca cccacaccgt
     1141 catgtactac ggccactaca gtaacgccac gctgaaccag ccgtgtggca gccccctgga
     1201 tggcagccag tgcacaccca gggtgggtgg cctgccctac aacatgcccc tggcctacct
     1261 ctccactgtg ggcgtgagct tctttatcac ctgcatcacc ctggtgtaca gcatggctca
     1321 ctctttcggg gagagctacc gggtgggcag cacctctggc atccacgcca tcaccgtctt
     1381 ctgctcctgg gactacaagg tgacgcagaa gcgggcctcc cgcctccagc aggacaatat
     1441 tcgcacccgg ctgaaggagc tgctggccga gtggcagctg cggcacagcc ccaggagcgt
     1501 gtgcgggagg ctgcggcagg cggctgtgct ggggcttgtg tggctgctgt gtctggggac
     1561 cgcgctgggc tgcgccgtgg ccgtccacgt cttctcggag ttcatgatcc agagtccaga
     1621 ggctgctggc caggaggctg tgctgctggt cctgcccctg gtggttggcc tcctcaacct
     1681 gggggccccc tacctgtgcc gtgtcctggc cgccctggag ccgcatgact ccccggtact
     1741 ggaggtgtac gtggccatct gcaggaacct catcctcaag ctggccatcc tggggacact
     1801 gtgctaccac tggctgggcc gcagggtggg cgtcctgcag ggccagtgct gggaggattt
     1861 tgtgggccag gagctgtacc ggttcctggt gatggacttc gtcctcatgt tgctggacac
     1921 gctttttggg gaactggtgt ggaggattat ctccgagaag aagctgaaga ggaggcggaa
     1981 gccggagttt gacattgccc ggaatgtcct ggagctgatt tatgggcaga ctctgacctg
     2041 gctgggggtg ctcttctcgc ccctcctccc cgccgtgcag atcatcaagc tgctgctcgt
     2101 cttctatgtc aagaagacca gccttctggc caactgccag gcgccgcgcc ggccctggct
     2161 ggcctcacac atgagcaccg tcttcctcac gctgctctgc ttccccgcct tcctgggcgc
     2221 cgctgtcttc ctctgctacg ccgtctggca ggtgaagccc tcgagcacct gcggcccctt
     2281 ccggaccctg gacaccatgt acgaggccgg cagggtgtgg gtgcgccacc tggaggcggc
     2341 aggccccagg gtctcctggc tgccctgggt gcaccggtac ctgatggaaa acaccttctt
     2401 tgtcttcctg gtgtcagccc tgctgctggc cgtgatctac ctcaacatcc aggtggtgcg
     2461 gggccagcgc aaggtcatct gcctgctcaa ggagcagatc agcaatgagg gtgaggacaa
     2521 aatcttctta atcaacaagc ttcactccat ctacgagagg aaggagaggg aggagaggag
     2581 cagggttggg acaaccgagg aggctgcggc accccctgcc ctgctcacag atgaacagga
     2641 tgcctagggg gacggcgatg ggcctcacgg gcccgcccag caccctgaga ccacactgtt
     2701 gcctcccagt gaccctgctg ggacaccagg acaaggaaga cagtttcgcc tctcgaaagc
     2761 cgcagctgcg cctaggctgg agctggaagg gtgggtgaat ccggcttggg catccccaat
     2821 gaactctgcc ctgcctggga ctctatttat tctgattaaa ggggttttgc aaatgggctt
     2881 gtcccttggg gctctgtgtc tgtgaccaca cccggggcct gcttcccgct gccctggggc
     2941 cacctccagg cgcaggtctg ggtcctggga acctcagctg gagtgggggc gccctctgct
     3001 ggccaagccc cagatggcag gggctggacc gcgccagggc ttgattcgct tgctgccttt
     3061 gaccagcctg aactcgcgcc caggaggggc ttacacctgc acaagtgagc cgagcaggca
     3121 cggattgtga ccagagcgat gcgtcaacca ttgggtgatg ctgtagcatc tactggagca
     3181 ggagacaaat ttagagaggg acttggaggg gagacatatc agttgcaaat gagttgtggg
     3241 gacagttgcc tcccaggcat aggtaaccag cacctgtgct tggaggcgaa cagggcttgg
     3301 tgaggtgggg ctggccccct gcttctggct gccagcagct ggctgggggg tggtgatcct
     3361 gggtctgact gggctgagtt tgaggagccc gtgggatacc gaaaaccgta ggctgtgggg
     3421 ggtgggcaca gggattcggg gaccagcccg tcatgacccc gtgctccagg tctgcaggga
     3481 ccagcccatg acagcccagg gctccaggtc tgcggggacc agcccatcac agcccagggc
     3541 tccaggcctg cggggaccag cccgtcagcc tcagttctcc aggcctgcgg ggaccagccc
     3601 gtcatgaccc cagtgctcca ggtctgtggg gaccagcccg tcagcctgtg ctccaggcct
     3661 gcaggaacca gcccgtcagc ctcagtgctc caggcctgcg gggaccagcc cgtcagcctg
     3721 tgctccaggc ctgcggggac cagcccgtca tgaccccagt gctccaggtc tgtggggacc
     3781 agcccgtcag cctgtgctcc aggcctgcgg gaaccagccc gtcatgaccc cagtgctcca
     3841 ggcctgcggg gaccagcccg tcatgacccc agtgctccag gtctgtgggg accagcccgt
     3901 cacggcgcag ggttccaggc ttgtggggac cagcctgtca cagcccaggg ctccaggcct
     3961 gcaggagctg cgcttgggat tgggggaatg aacccaggtg gggaaatggt caaagagcga
     4021 tgggcccaga aaagggtcag acccagatgg agatgccact ggctgctagc agacccccac
     4081 gctgggtcta gcccacccaa tcccatgggg atgctcctgt gctctgcaga catctgggtg
     4141 ctgccacagg ggcccgacag agttggcatc tgggtggatc tgagccaagt ggtgcttctg
     4201 ggcctcagca agtagctggt gctgattctg ggcagccaac tgtggcagca tcttcaggtg
     4261 cgagtgctgc tgggtgaagc tgcgtgggca gtccagaaag tgacgtgaca gtccacaggg
     4321 accgacgtag ggtttccagc ccctatctgt gcagatgctg tcctccaaac catcacggtc
     4381 cctctctggc tggggacgtg cgcctgccac tgctggcttg ccagcatgat cattggttgt
     4441 gacctgttga gcccatcttg ccagcctcac aaaggacagt actagctgct tatgacagga
     4501 aagtggaaga acttggcctg gatatttctg gagaattacc gtgtgtgcta gtcagtcttt
     4561 cgtgtcaacc aggccaggct gtggggccca gtgatctcat cgagaggggc cgaggtgttg
     4621 ctgtgatcgt gtgctgctgg aatgtggtga acacctacag tcgatttcac ctaaagatca
     4681 tccttgagaa tgtgggtggg cctcatccta tcagctgaaa gctttaagag caaaacccga
     4741 ggtgtcccag agagggaatt ctgccttgag acggcggctt cccactccca ctggatgtcc
     4801 agcccgcggc cccacggctg ggtgagcccg tcctctcctc gtttctgtct ccggacccac
     4861 cgtgtggccc cagaccctcc agtgaggacc tcccgtattt cttcagagca gcccttgcgt
     4921 gctggaggcc tgggcttcag tgtgtccctg ggtgccctgg ggcatgttct gtgacctccc
     4981 agctcctcgc ctcatggggc cgctgtatca agtgacacag tttgtgtgct gcgtaccatg
     5041 cctggcaccc atttgaggtg ttgcaaggag gccatgtttg ctcgatgaga gcagcctaag
     5101 atctacaaac tgttgttcga gtggatggga acttgatgct attttcaggc tgaatgacaa
     5161 gactccgcga tgcttctcgg cctgggctgc acaacggaat ctaccaggga ggttttaaaa
     5221 acactggtac ttgctggagg tggtggcgcc tgtctgtaat tgcagctgct ccagaggctg
     5281 aggcggagga ttgcttgagc ccaagagttt cggtttattt gctttttcag agtcttgctc
     5341 ttgcccaggc tggagtgcag ttccatgatc tcggctcact gcctcagcct cccaagtagc
     5401 tgggattaca ggtgcataca accaggcctg gctgatcttc gtatttttag tagagatggg
     5461 gtttcaccat gatggtcagg ctggtcaaga tctcctgacc tcaagtgatc tgcccgcctc
     5521 ggcctcccaa agtgctggga ttacagacat gaaccacaac acctgccgag cccaggtgtt
     5581 ttgaatccag cacgggcaat ggcaagaccc tgtcccaaca aacaaaaaaa cactggtgcc
     5641 tgaggcccac cccgagagat tctgattgag ttgatttgga tttgaattat ctttaaaatt
     5701 ttggatgtga attttttttt tttttcttgg aatggagttt cactcttgtt ccccaggctg
     5761 gagtgcaacg ggacgatctt ggctcaccgc aacctccgcc tactgggttc aagccattct
     5821 cctgcctcag cttcccaagt agctgggatt acaggcatgt gctaccatgc ccagctaatt
     5881 ttgtattttt agtagagaca gggtttctcc atgttgctca ggctggtctt gaactcctga
     5941 cctcaggtga tccgcccgcc tcggactccc aaagtgctgg gattacaggc atgagccacc
     6001 atgcctggcc ggatgtgaat tatcttaaaa attttcaggt aattctaatg ggccaaggtt
     6061 gagaacccct gctctgggcc catccgagca ccaggctgtc acaaacgcat gcatgcactc
     6121 acgcccgtgg gcttgggggg cttcggaaat gtgcttctgc ttttttgaga tggggtcttt
     6181 ctgttgccca tcccggagca cagtggcacg atcacagctc actgcagcct cgacctcctg
     6241 ggctcaggtg atcctcccgc ctcagcctcc tgagtgtctg cttctggttt tcatgatgac
     6301 ctggggccca ggcatactac acttgtgctg ttcaggggcc agtcctgcac caggagccca
     6361 tcagccacag ctccgccgag aagcactgat atgcagagct aagcagcttt gtttccacgt
     6421 ggatcctgcg taggttttct tggtccatcc gtagacaccg cactcctgca gaggatcttc
     6481 tcgggatgcc ccactgtctc tgttttccct cttcactgaa cactcagtcg gggctcgcca
     6541 tgatgcctct gtgtctgctg gcttctcccc cattggaaca gccttcttgg cacgccacac
     6601 tgctagctgc tgggcactgt gctttctgcc tttaccgttc tgccgtgatg ttgccaaaat
     6661 agcagcaaca acaacaacaa caaaggctgg gcacctggct catgcctgta ttcccagcag
     6721 ttcgagatca gcctgggcaa catgccccaa ctggacccta ggcaaaagtg agtggcactc
     6781 ctctgccagg actccaggca agccccggca tcttcttgct gccgtcccag acaacagaag
     6841 ttaccagatg aacagacttg gatgggccac gggggtggag agctggaaag cttggctgtg
     6901 cctctcgatg atgattaaga tttcaatatt tacagcaaaa ccacaaagca aatgatagaa
     6961 taaagcaaaa caatggaaaa tctgagttca ctcgtgagag aggtacgtat gtgagctctg
     7021 aggaaattac agagggaacg catgcagcgg gacagctctc ccaatcgcag cgtgcaaagt
     7081 agacatccat agtgtctttt gaaaaatgaa aaacacatta ctttgaacag ccaagaaaaa
     7141 aattgcaatt tattaagatt caataaagcg ttgtactttc gaaagcaa
//
