LOCUS       NM_015933                561 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens translation machinery associated 7 homolog (TMA7),
            transcript variant 1, mRNA.
ACCESSION   NM_015933
VERSION     NM_015933.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 561)
  AUTHORS   Song,Z., Zhou,C., Wang,J., Yang,W. and Hao,F.
  TITLE     Effect of HSPC016 gene expression on the aggregative growth of
            dermal papillae cells
  JOURNAL   Australas J Dermatol 53 (2), e26-e29 (2012)
   PUBMED   22571579
  REMARK    GeneRIF: Dermal papillae cells (DPC) lose aggregate behavior and
            grow much slower after HSPC016 gene inhibition. Recombinant HSPC016
            protein promoted the proliferation of high-passage DPC and induced
            aggregative behaviour.
REFERENCE   2  (bases 1 to 561)
  AUTHORS   Zhiqiang,S., Jiwen,W., Fei,H., Weibin,Y., Feng,Z., Xichuan,Y. and
            Chunlan,L.
  TITLE     Identification of differentially expressed genes HSPC016 in dermal
            papilla cells with aggregative behavior
  JOURNAL   Arch Dermatol Res 297 (3), 114-120 (2005)
   PUBMED   16096800
  REMARK    GeneRIF: HSPC016 was was differentially expressed in dermal papilla
            cells with aggregative behavior.
REFERENCE   3  (bases 1 to 561)
  AUTHORS   Yang,W.B., Hao,F., Song,Z.Q., Yang,X.C. and Ni,B.
  TITLE     Apoptosis of the dermal papilla cells of hair follicle associated
            with the expression of gene HSPCO16 in vitro
  JOURNAL   Exp Dermatol 14 (3), 209-214 (2005)
   PUBMED   15740594
  REMARK    GeneRIF: Expression of gene HSPCO16 resulted in the apoptosis of
            these cells, which suggested that the apoptosis of dermal papilla
            cells might be associated with the expression of gene HSPC016 in
            vitro.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BU536461.1 and AA149268.1.
            
            On Nov 23, 2018 this sequence version replaced NM_015933.5.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066333.1, BG715787.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000438607.2/ ENSP00000397843.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-380               BU536461.1         28-407
            381-561             AA149268.1         1-181               c
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.31"
     gene            1..561
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /note="translation machinery associated 7 homolog"
                     /db_xref="GeneID:51372"
                     /db_xref="HGNC:HGNC:26932"
                     /db_xref="MIM:615808"
     exon            1..56
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..235
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 72; coiled-coil
                     domain containing 72; translation machinery-associated
                     protein 7; translational machinery associated 7 homolog"
                     /codon_start=1
                     /product="translation machinery-associated protein 7
                     isoform 1"
                     /protein_id="NP_057017.1"
                     /db_xref="CCDS:CCDS46823.1"
                     /db_xref="GeneID:51372"
                     /db_xref="HGNC:HGNC:26932"
                     /db_xref="MIM:615808"
                     /translation="MSGREGGKKKPLKQPKKQAKEMDEEDKAFKQKQKEEQKKLEELK
                     AKAAGKGPLATGGIKKSGKK"
     exon            57..112
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /inference="alignment:Splign:2.1.0"
     exon            113..200
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /inference="alignment:Splign:2.1.0"
     exon            201..561
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /inference="alignment:Splign:2.1.0"
     regulatory      369..374
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /note="hexamer: AATAAA"
     polyA_site      394
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /note="major polyA site"
     regulatory      538..543
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /note="hexamer: ATTAAA"
     polyA_site      561
                     /gene="TMA7"
                     /gene_synonym="CCDC72; HSPC016"
                     /note="major polyA site"
ORIGIN      
        1 gtttccggtg gcagggtctg gggaagcggc ggcaggcgcc atgtccggcc gcgaaggtgg
       61 caagaagaag ccactgaaac agcccaagaa gcaggccaag gagatggacg aggaagataa
      121 ggctttcaag cagaaacaaa aagaggagca gaagaaactc gaggagctaa aagcgaaggc
      181 cgcggggaag gggcccttgg ccacaggtgg aattaagaaa tctggcaaaa agtaagctgt
      241 tccttgtgcc tgaggagatg gtgacccttt atttcatctg tatttaaacc tctctattcc
      301 ctgccataac atcttttgcc acgtatagct ggaattaagt gttgtcttgg agctgttgta
      361 catttaagaa taaacttttg taaaaaaaga aaaatcttac agtggctcat catctcttta
      421 gttgttttca ctaagtcgtt cctaccataa ctgtgaattt aaagtaaaac cagctcagaa
      481 tcttgccaga gtctgttctt tggtccttgt tctaccctaa actttgtatc acctgaaatt
      541 aaaccaactc atttgaaagg a
//
