LOCUS       NM_001367365            1790 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens TLE family member 7 (TLE7), mRNA.
ACCESSION   NM_001367365
VERSION     NM_001367365.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1790)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC010547.9.
            
            On Aug 28, 2019 this sequence version replaced NM_001367365.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2148874
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000561754.4/ ENSP00000492311.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                AC010547.9         47896-47981         c
            87-493              AC010547.9         38941-39347         c
            494-516             AC010547.9         38797-38819         c
            517-575             AC010547.9         38592-38650         c
            576-791             AC010547.9         38037-38252         c
            792-1033            AC010547.9         37688-37929         c
            1034-1175           AC010547.9         37348-37489         c
            1176-1329           AC010547.9         37048-37201         c
            1330-1403           AC010547.9         36595-36668         c
            1404-1790           AC010547.9         35907-36293         c
FEATURES             Location/Qualifiers
     source          1..1790
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q22.2"
     gene            1..1790
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /note="TLE family member 7"
                     /db_xref="GeneID:102723796"
                     /db_xref="HGNC:HGNC:53648"
     exon            1..86
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     exon            87..493
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..1508
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /note="transducin-like enhancer protein 2; transducin like
                     enhancer of split family member 7"
                     /codon_start=1
                     /product="transducin-like enhancer protein 7"
                     /protein_id="NP_001354294.1"
                     /db_xref="CCDS:CCDS92193.1"
                     /db_xref="GeneID:102723796"
                     /db_xref="HGNC:HGNC:53648"
                     /translation="MSGEKEEASLRMFGAYGEPEERRDVLESSGVSSQPEPQVQQQLG
                     SLLGVPWQPPGPPIQHSPADQETSTVTQQQWHLQGLGRSELQAAGLPDAQPGEAAESS
                     PSFLLGSEVGQPYSSSSPSEEVLSLLRAIPPIPDEVVVRQKRAPQGSWKVGTLFHGKR
                     VYAVAISGSTHHVYTCGSGYIRVWDESALHAGEKAPRAQLDLQHPQDRVVTCKLFPDE
                     RSLITGGASQAVTLWDLAPTPQVRAQLTSTGPTCYSLAVSSDAHICLACFHGFVEIWD
                     LQNQILIRKHEVPVYGSRCVDITGNIFWTGGEDTILYSWDLRSYQRLHQHNLQNEILS
                     ITHDPGEEWVLAGLRTSDIVFLHTRRNEQFKALMKKYTRHHSLKFASCGSYFVTAIDT
                     RLSGLEAPSLQKLFQIEESSGILCCDVSSDNQYLVMGSSSSATIYQLLY"
     exon            494..516
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     exon            517..575
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     exon            576..791
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     exon            792..1033
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1175
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1329
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1403
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1790
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1765..1770
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /note="hexamer: AATAAA"
     polyA_site      1790
                     /gene="TLE7"
                     /gene_synonym="chico"
                     /note="major polyA site"
ORIGIN      
        1 agcctccagg aagccttccc gactgccctg cggcaccaag cctccgtcct ctggttgccc
       61 cgagggacct cagcgccccc gccacgggga tcaggacaca ctgggaacct ggtgtctgtt
      121 tggcgggtct atttgtcaag tcctagaacc gggtggtcca gacacctcac tgatctaaga
      181 acatgagtgg agagaaggaa gaggcatcgc tcagaatgtt cggggcttat ggtgagccag
      241 aggagaggag ggatgtgctg gaaagctctg gcgtttcctc tcagcctgag ccacaagtgc
      301 agcagcaact gggcagtctg ttgggagtgc cctggcagcc cccgggcccc ccaatacagc
      361 acagccctgc tgatcaagag acaagcacgg tgacccagca gcagtggcac ctccagggcc
      421 tgggtagatc tgagctccag gccgctgggc tccctgatgc acaaccagga gaagcagcag
      481 agtccagccc aagcttccta ctgggttctg aggttggcca gccttactct tcttcctctc
      541 ccagtgaaga agtcctctca ttgctcagag caattccccc cattccagat gaagttgtgg
      601 tcaggcagaa gagggcccca cagggctcct ggaaggttgg cacactcttc catggaaaga
      661 gagtctacgc tgtggccatc agcggctcaa cccaccacgt gtacacgtgt ggctctggct
      721 acatcagggt atgggatgag agtgcgctgc atgcggggga gaaggcccct cgggcccagc
      781 tggacttgca gcatccccag gaccgtgttg ttacctgcaa gctgttccct gatgagcgga
      841 gcctgatcac agggggtgcg tcccaggccg tgactctctg ggacttggca cccacccccc
      901 aggtcagggc acagctgacc tcgacgggcc ccacgtgcta ttctctggct gtctcctctg
      961 atgcccatat ctgtttggct tgtttccatg gatttgttga gatttgggat ttgcagaacc
     1021 aaatcttgat caggaagcac gaagttcctg tatacgggtc ccgatgtgtg gacatcaccg
     1081 gcaatatatt ctggacagga ggtgaagaca ccatcctgta ttcctgggac ctgaggagct
     1141 accagaggct gcaccaacac aacttacaga atgagatcct cagcattacc cacgaccccg
     1201 gtgaagaatg ggtattggcg ggcctgagaa cgagtgatat cgtgttcctt cacactcgtc
     1261 ggaatgagca gtttaaggct ctcatgaaaa aatacacccg ccaccacagc ctcaagtttg
     1321 cctcctgtgg gagctatttt gtgaccgcga tagatacgcg cctcagtggc ttggaggcac
     1381 cttctctgca aaagttgttt cagatagagg agtcttcagg tatcctgtgc tgtgacgtgt
     1441 cctctgacaa ccagtatctg gtcatgggct ctagcagcag tgccaccatc taccagctct
     1501 tgtattaaag gtggcatgcc atggtcctgc cagtgaagac ccagtctttg ggctggtgtg
     1561 gctgtgagga tggcttcaga gtgctggaca cctctaacac ctgccatctc ctctgcctta
     1621 gcttgggtca tccctcccct ccagtagccc gctctcagcc tgcactccca gattttaatc
     1681 agatggcttg gagctttttc ctttgttatc ttcctaccac tgatttctgg gttttggcag
     1741 gaaacttgag atccctttgt aatgaataaa atagcaaagc agaaagcaaa
//
