LOCUS       XM_011518961            4997 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens TLE family member 4, transcriptional
            corepressor (TLE4), transcript variant X14, mRNA.
ACCESSION   XM_011518961
VERSION     XM_011518961.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011518961.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4997
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..4997
                     /gene="TLE4"
                     /gene_synonym="BCE-1; BCE1; E(spI); E(spl); ESG; ESG4;
                     Grg-4; GRG4"
                     /note="TLE family member 4, transcriptional corepressor;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 44 ESTs, 622 long SRA reads, 4
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 12 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:7091"
                     /db_xref="HGNC:HGNC:11840"
                     /db_xref="MIM:605132"
     CDS             827..3259
                     /gene="TLE4"
                     /gene_synonym="BCE-1; BCE1; E(spI); E(spl); ESG; ESG4;
                     Grg-4; GRG4"
                     /codon_start=1
                     /product="transducin-like enhancer protein 4 isoform X14"
                     /protein_id="XP_011517263.1"
                     /db_xref="GeneID:7091"
                     /db_xref="HGNC:HGNC:11840"
                     /db_xref="MIM:605132"
                     /translation="MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQA
                     QYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQHQQQVVQAVERAKQVTMA
                     ELNAIIGQQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQS
                     HLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKE
                     IAARYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASI
                     ASSSSTPSSKSKELSLKRDMGKLSETRLSEDEQCTLGLQRWFCRLWFMNEKSTTPVSK
                     SNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSLRTPMAVPCPYPTPFGIVPHA
                     GMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSPVVGFDPHHHMRVPAIPPN
                     LTGIPGGKPTKCFYHLRAFPGNELEMELPRDTHRAYSFHVSADGQMQPVPFPPDALIG
                     PGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDC
                     LNRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISP
                     DSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRS
                     WDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESC
                     VLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGS
                     GDKKATVYEVIY"
ORIGIN      
        1 agagcgtgtt gttagagctg tgctgagcgg gtgtttgggt tgttggctgc tttcttcccc
       61 ctttctcaca cacttgtata ttattttgag gtggtgttcg cagagtttga aaggagagag
      121 aattaaaaaa aaaagccgca agcgtttcac tcttttattt ttataatccc cttcaatttg
      181 gggttaaaaa aaagacaaga aaacaggaag gaagagaaat aaggaaatga gatgtggtaa
      241 aagaagctaa aaggtgcctt ttaaaagatc gttgctgtga agtgaaaaaa atctccagag
      301 aaaccaaaaa gcaccgccga gacctcttcc gaaccaaagg agtttgtgtt tgcttttagg
      361 gaagaagaaa gatcattcat tcggaggaat aacaaccaat taaaagacaa ataaaaaaag
      421 tttggagtgg gacgcagagc gagcgagagg agctgccggc gggcggtggg gcgcggagcc
      481 cgcactttcc cggccgggtg agcggcggcc gcggcgccgg gctcggcggg tgcgcctcgg
      541 cggagcgaac gtcggagcgt tgccttggga gacgcgcgcc ggacaatgcc cgcggcgggc
      601 cagtgacgcc cgcggggaat gcggagcggc ccggcagccg gcacccagcc gccgccgcgc
      661 gttcctgccg cccgtgtcac gcgagacccg gcgggggccg ggaccgcccg agccgcccct
      721 cagaccgagc cggccgcctc cgctgccgcg gccgcctcct cttcggggtc attaaagcca
      781 atgagccgcg cgcctctgcc gagcgcagcc aactaaatcg gcttggatga ttcgcgacct
      841 gagcaagatg tacccgcaga ccagacaccc agcaccgcat cagcctgctc aaccctttaa
      901 atttacaatt tccgaatcct gtgatcggat taaggaagag tttcagtttt tacaggctca
      961 ataccacagt ctgaagctgg aatgtgagaa actcgccagt gagaagacag agatgcagcg
     1021 gcattatgtc atgtattatg aaatgtccta tgggttgaat atagaaatgc acaagcagca
     1081 ccagcaacaa gtggtgcagg ctgtggaacg ggccaagcag gtgaccatgg cagaactgaa
     1141 cgccatcatt gggcagcaac aactccaggc ccagcattta tcacatggac atggtctccc
     1201 cgtacctctg actccacacc cttcagggct ccagccccct gccattccac ccatcggtag
     1261 cagtgccggg cttctggccc tctccagtgc tctaggaggt cagtcccatc ttccaattaa
     1321 agatgagaag aagcaccatg acaatgatca ccaaagagac agagactcca tcaagagctc
     1381 ttcagtatcc ccatcagcca gtttccgagg tgctgagaag cacagaaact ccgcagacta
     1441 ctcctcagag agcaaaaagc agaaaactga agaaaaggaa attgcagctc gttatgacag
     1501 cgatggtgag aaaagtgatg acaacttggt ggttgacgtt tccaatgagg atccatcttc
     1561 ccctcgaggg agcccagcac attcccccag agagaatggc ctagacaaga cacgcctgct
     1621 caagaaagat gccccgatta gtccagcctc tattgcatct tccagcagta ctccctcctc
     1681 caaatccaaa gaacttagcc ttaagaggga tatggggaaa ttgagtgaaa cacgtcttag
     1741 cgaagatgaa caatgcacat tggggttaca gagatggttt tgtcgcctgt ggtttatgaa
     1801 tgaaaaatct actactcccg tctcaaagtc caatacccct actccacgaa ctgatgcgcc
     1861 caccccaggc agtaactcta ctcccggatt gaggcctgta cctggaaaac caccaggagt
     1921 tgaccctttg gcctcaagcc taaggacccc aatggcagta ccttgtccat atccaactcc
     1981 atttgggatt gtgccccatg ctggaatgaa cggagagctg accagccccg gagcggccta
     2041 cgctgggctc cacaacatct cccctcagat gagcgcagct gctgccgccg ccgctgctgc
     2101 tgctgcctat gggagatcac cagtggtggg atttgatcca caccatcaca tgcgtgtgcc
     2161 agcaatacct ccaaacctga caggcattcc aggaggaaaa ccgaccaaat gcttttacca
     2221 cctgagggct ttccctggaa atgaactgga gatggaactg ccaagagata ctcacagagc
     2281 atactccttc catgttagcg cagatggtca gatgcagcct gtcccttttc cacccgacgc
     2341 cctcatcgga cctggaatcc cccggcatgc tcgccagatc aacaccctca accacgggga
     2401 ggtggtgtgc gcggtgacca tcagcaaccc cacgagacac gtgtacacgg gtgggaaggg
     2461 ctgcgtcaag gtctgggaca tcagccaccc aggcaataag agtcctgtct cccagctcga
     2521 ctgtctgaac agggataact acatccgttc ctgcagattg ctccctgatg gtcgcaccct
     2581 aattgttgga ggggaagcca gtactttgtc catttgggac ctggcggctc caaccccacg
     2641 catcaaggca gagctgacat cctcggcccc cgcctgctat gccctggcca tcagccccga
     2701 ttccaaggtc tgcttctcat gctgcagcga cggcaacatc gctgtgtggg atctgcacaa
     2761 ccagaccttg gtgaggcaat tccagggcca cacagatgga gccagctgta ttgacatttc
     2821 taatgatggc accaagctct ggacaggtgg tttggacaac acggtcaggt cctgggacct
     2881 gcgcgagggg cggcagctgc agcagcacga cttcacctcc cagatctttt ctctgggcta
     2941 ctgcccaact ggagagtggc ttgcagtggg gatggagaac agcaatgtgg aagttttgca
     3001 tgtcaccaag ccagacaaat accaactaca tcttcatgag agctgtgtgc tgtcgctcaa
     3061 gtttgcccat tgtggcaaat ggtttgtaag cactggaaag gacaaccttc tgaatgcctg
     3121 gagaacacct tatggggcca gtatattcca gtccaaagaa tcctcatcgg tgcttagctg
     3181 tgacatctcc gtggacgaca aatacattgt cactggctct ggggataaga aggccacagt
     3241 ttatgaagtt atttattaaa gacaaatctt catgcagact ggacttctcc tcctggtagc
     3301 actttgctct gtcatccttt ttgttcaccc ccatccccgc atctaaaacc aaggatttca
     3361 gatactcatt gcagttgtgg agtttaatcc cctttcttaa cctcacttcc cacttgctat
     3421 tgaattgtga atagtcatta aaaacctgtg ataccaaatc ttcagctgtc tacttggaag
     3481 aacatggaat aagcatactt aacagtgaaa agaatcttta attatgtatt atatctgtaa
     3541 tatatttatt ttgtttaaag aaggctttct aacaatgact gactaaataa agctgtctgc
     3601 tcctgcattg ataatgaagg tgcgttgtat ttgatacccc tccccccctt tttttggcaa
     3661 aggaggggaa aggaaggttt aaaataattg atttaaaatg tcactaagtg tagactgatg
     3721 actgtataga gatgtgaaat gtataattac acatggaagc aatatgttgc tgtgttgtta
     3781 ttaggttttt tttgtttttg ttttctacat cttttaaaga cttttggaaa tttggctgaa
     3841 caattagaac acaacaggcc aactcatact catttggatc tatttagaca acgttaacca
     3901 atatatctat agctttagat tatattcgat aaaagtaatt ggactttttt tctttttttg
     3961 actcgttgac aagtgtcttt gtaatatgtt tttagttccc tttttttgtt gtattatagg
     4021 cagatgaaca aattaaattt ggcctcaaag agagaactta ctcccttctg gatatttttg
     4081 ccacatttct ttgcaaaagg agatatatat atctttagtc agttttgttg ttatgagaaa
     4141 ttatgggtta ttttgtggca tgctctttgg gagctgcaca gttatgggga ggactcccac
     4201 tgctgtgcaa gttaagtctt ttacaaaaca aggacagcag aggagggttt gcagagacct
     4261 ccctctgaaa aacacaaaga atggactctc tcctgggatg aggacttgct ttctttacct
     4321 ccggttcttt ccatgtctta gttggatgtc cctgaaatgg acacaggctg tgccattgtg
     4381 ccagaaacat tgtgttatct tttatgttgt tgttgttgct gttaaactat aatatgtgac
     4441 ttcttttttt attatttttt gtttgaatgc tttaaaaatc ttttaagtct gtggatctgc
     4501 tgatgtacag tgcctttgct gctatggatc aaaatcaaaa gaaccgtgta gatatacttt
     4561 attgtataag tagaaaatta cttaatttca tactagaaat ggatggatgc tgcaagttga
     4621 aatggactgt ccattgacgt tcctaatgtg gtagcagaaa aaaaaaaatg gtgtcttaag
     4681 tgcttagtgt ttgatgtcat taacagtttc gtaaaactct acagtgtaga aagattttga
     4741 tactaaactg tgcgttgtac atagttctaa tgcattgtat tgaccaccag tacttctata
     4801 atggtagatt gtttgtgaat tcagactttt aagcattaaa cataaataac ttctagtatg
     4861 cttatttttc taattctttg tcttgatgac attagtttat tttttatctt tggctgtgcc
     4921 actcctatat attaaaaatg cctagttttt tcaagggaga ttgttgttaa agtaaagtgg
     4981 ttttttttgt tgttaaa
//
