LOCUS       XM_047447936            7844 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens TCDD inducible poly(ADP-ribose) polymerase
            (TIPARP), transcript variant X2, mRNA.
ACCESSION   XM_047447936
VERSION     XM_047447936.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7844
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..7844
                     /gene="TIPARP"
                     /gene_synonym="ARTD14; PARP7; pART14"
                     /note="TCDD inducible poly(ADP-ribose) polymerase; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 ESTs, 538 long SRA reads, and 98% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     4 samples with support for all annotated introns"
                     /db_xref="GeneID:25976"
                     /db_xref="HGNC:HGNC:23696"
                     /db_xref="MIM:612480"
     CDS             249..1526
                     /gene="TIPARP"
                     /gene_synonym="ARTD14; PARP7; pART14"
                     /codon_start=1
                     /product="protein mono-ADP-ribosyltransferase TIPARP
                     isoform X2"
                     /protein_id="XP_047303892.1"
                     /db_xref="GeneID:25976"
                     /db_xref="HGNC:HGNC:23696"
                     /db_xref="MIM:612480"
                     /translation="MEMETTEPEPDCVVQPPSPPDDFSCQMRLSEKITPLKTCFKKKD
                     QKRLGTGTLRSLRPILNTLLESGSLDGVFRSRNQSTDENSLHEPMMKKAMEINSSCPP
                     AENNMSVLIPDRTNVGDQIPEAHPSTEAPERVVPIQDHSFPSETLSGTVADSTPAHFQ
                     TDLLHPVSSDVPTSPDCLDKVIDYVPGIFQENSFTIQYILDTSDKLSTELFQDKSEEA
                     SLDLVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQ
                     KWQSVFNDSQEHLERFYCNPENDRMRMKYGLQNFAEQRLPLHLHEANFQSAEYFSILR
                     CCVSWQQDADNGMLSLAERFTNKLEQPRFTWLPHYLAKAINLCGQACKAGLSVQIAHN
                     QEVCVQLCICRSWNQQSLDSEIMNGSCLSHCFQ"
     polyA_site      7844
                     /gene="TIPARP"
                     /gene_synonym="ARTD14; PARP7; pART14"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agagatcgag gtgacaggcg agctggctgg actcggagcg cggtcgaggc tttctgcgtt
       61 cgcggcggcg gaatggcccg tgcgcggctc gccgcgtcgc ggctctgtgg tccctagacg
      121 tcggctcccg ccctcggcgc tgatctccgg cgcgggcact gctttccact cggctcctgt
      181 cgtccgttct ctcaggctcc cgttcaggat ttttagactc tgaggagcag ttggagctaa
      241 tccacattat ggaaatggaa accaccgaac ctgagccaga ctgtgtagtg cagcctccct
      301 ctcctcctga tgacttttca tgccaaatga gactctctga gaagatcact ccattgaaga
      361 cttgttttaa gaaaaaggat cagaaaagat tgggaactgg aaccctgagg tctttgaggc
      421 caatattaaa cactcttcta gaatctggct cacttgatgg ggtttttaga tctaggaacc
      481 agagtacaga tgagaacagc ttacatgaac ctatgatgaa gaaagccatg gaaatcaatt
      541 catcatgccc accagcagaa aataatatgt ctgttctgat tcctgatagg acaaatgttg
      601 gggaccagat accggaagcc catccttcca ctgaagctcc agaacgagtg gttccaatcc
      661 aagatcacag ctttccatca gaaaccctca gtgggacggt ggcagattcc acaccagctc
      721 acttccagac tgatcttttg cacccagttt caagtgatgt tcctactagt cctgactgct
      781 tagacaaagt catagattat gttccaggca ttttccaaga aaacagtttt acaatccaat
      841 acattctgga caccagtgat aagctgagta ctgagctctt tcaggacaaa agtgaagagg
      901 cttcccttga cctcgtgttt gagctggtga accagttgca gtaccacact caccaagaga
      961 acggaattga aatttgcatg gactttctgc aaggcacttg tatttatggc agggattgtt
     1021 tgaagcacca cactgtcttg ccatatcatt ggcagatcaa aaggacaact actcaaaagt
     1081 ggcagagtgt attcaatgat tctcaggagc acttggaaag attttactgt aacccagaaa
     1141 atgatagaat gagaatgaag tatggattgc aaaactttgc agaacagcgg ctcccacttc
     1201 accttcatga agcaaatttc cagtctgctg agtacttcag catcttgcga tgttgtgttt
     1261 cctggcaaca agatgcagat aacggcatgt tgagccttgc tgagagattc acaaacaagc
     1321 tggagcagcc caggttcaca tggttaccac attatttggc taaagctatt aatctctgtg
     1381 gtcaggcctg taaagctggt ctatctgtgc agattgcgca taaccaggaa gtgtgtgttc
     1441 agctgtgtat atgtcgaagt tggaaccagc agtctttgga ttcagaaata atgaatggca
     1501 gttgtttatc ccactgtttt cagtagttta tatggcttgg taaatcatta tcatattctg
     1561 tatccataac atcttcattg tgtgatatac ttggggaaag ttcatagttc tgggtctcta
     1621 gcagagatga aagttcatag tttcaaactg tacagataaa atcttttatt tagctttgca
     1681 aatgtattgg atttaatacc taaatctaaa ttatatgtat agtgttcatt ttgttctcag
     1741 gaatgaaatt ggaaaggaag ttgaactaga taaattcaca ggacctttcc aactttttag
     1801 tcaagatgct tagatactaa aagcacatta aaaaaggatt tcaataatac atgcttattt
     1861 gttccttgta atgaaattat gatgtaatcc cactttgctt tctcattttg cttttgtaca
     1921 tctacaaacg ttcattgcca acatcaactg catactagtg tgtatgtact tcccagatat
     1981 agatgctgag gcttcttttt tgcacacgag atgagccttg gagaatttcc aaattccaaa
     2041 tatacagttg agaaacaaca ttgagtgttg tgttttcgat taagaaaaca gagtctggaa
     2101 cagtgtaggc actcatcctt agtagacgat gacattggat ggcagaatta agcagtttta
     2161 aaagagcctt gcacactgtg gagtactgtt gtggataatt gaaattatgg aggttgtgca
     2221 aatctctctt tagcaaacaa gatcaccact agtttcatat tacattcatt ttaaattgag
     2281 ccagaacaat tttctattta tttccacctg tcaagaaggg acacactgca aaccttattt
     2341 tggaggctac ctgcaggtgc acatgtgacc aatgattatt tctaattctg aatttattga
     2401 aagagagtgg aggtgaagag gaagaggaaa gttgcaaacc ctgaatccat tattaatttt
     2461 tttcagagga cagggttttt ttcttttggg attaatgctc actgataaaa gagggagctt
     2521 tagttgcttt aaggcttaag gctagagtgt tgtcatagtt ttagttgctg agtgattttg
     2581 attgctaatt gcccttagaa gtctattttt aaactctgtc caagggacaa taccattaga
     2641 tgacttcaca gaaactctat ataaaagaga aatgtatatt aatgatcata aaaagcatat
     2701 actgttacag tccctatatg acttgcatag tgaattagct aaactagagc aagctcctga
     2761 ctgaactcta ctggagtagt taaattagcc aagttagctc tggcgtgcac agctgtgatg
     2821 atgtatgaac taactcatta tgtgttattg ataacactgg agagaggaga acagctgaaa
     2881 cttactatgc cttgtgactt tttggtagtt cttgaatata cacagctgga tgagtttaaa
     2941 tttattttaa aaatttctgc ctaagagaaa gacagctcca taagcaagaa ctgtgtttga
     3001 agtgactttc aaaatgtgtg ccttgtgctt taggataaag caatccaatg aattattttt
     3061 tgtacttctt tatgctacta tttacatatg aaataaaact aattggcttc tgtctatact
     3121 aacccagaga agttactgga tctgtgtaga gctgtcatgg caatcaatag caatcattta
     3181 tttattccct ttttggtttt tcatcaataa gcagattaga ctttttgaag cagctgccac
     3241 ctggcttcag gttggggtca ttcttttcct gatgtattta tggtaatgaa aatgaacctt
     3301 gtcaaaatga tttataactt ttaaatcaga cagttggagg aaatagcttg taaggttatg
     3361 tggcattccc taaaaataat tgcatgatac attatatatt ttatcattga gttgaatcca
     3421 aagctcttac tttttattgt aagtaagaaa aaaaaggaat acaagttgaa tatcccttat
     3481 ccaaaattct tggagaccag aagtgtttca gattttggat tttggaatat ttgcatagta
     3541 ccccagttaa gcatctgaaa tccgaaatgc tccagtgagc atttgggtat catcttggtg
     3601 ctcagaaagt tttgggtttg aagcacttcc gattttcaga tttggggtgc tcaatttata
     3661 gtagtaactc cattcagcat ttaaaatttc attctgcaca tagtgggcat gcaaaaaaaa
     3721 aaatgctgac ttttgactga taactctgtt gtgtccctgt aaatctattt cctattatac
     3781 tagaattatc ctattatact agaatttcta gatcatagat ttacaatcta ccataaagta
     3841 aagataaact tcataagttc ttctgtgtat ttctaatcat ggtcagtgat ccttagtttt
     3901 attctgggtt tgggtgctat tcctaaagga taaagcagta tgtagtctat gcaaaccttg
     3961 actactcaag gaatgctaca aaaatacagc catttgagat tatgactttt ttcccatggt
     4021 ctcttttatt tttatctcct gatttgagac caccagattc tgcatccttt gtctgatggt
     4081 gatgattctg gattgcattt aaattaggac cttaagtcct cttaacctta gccaacaacc
     4141 tttaataatt atcagtctcc aatttgtgag ttgcaattgt ctttttgtgg aaggaaaact
     4201 tagtacatgt gtatatcatt ttttgcaaag gaaaaaacat atttcaaatt gcaagataat
     4261 tattttggca caacttgtat ggctagttca aattggacac tgtaaaagtt ttgaaagaaa
     4321 ctcactttgt aaaagtagga gagtttctct tttataataa gattggggtc ttaaggtaaa
     4381 gtgagttcga gagattttgt atctttgaaa aagaccacag tgctgaaggt taagccattt
     4441 tccctttgat tctgggtttg aaataggtga tagcctgaga tcttgatttt accgctactt
     4501 tgcaacacct taaacagaaa ctgtacaagg aataaaatac ttctgaagtt caccatttct
     4561 aggagcaaac aagccacatt ttagatgtga aggaattcct tttttttgag accaagtttc
     4621 aggctggagt gcagtggcat aatctcggct cctgcaacct ccgcctcctg ggttcaagca
     4681 attctcctgc ctcagccttc ctgagtagct gagattacag gcatgcgcca ccatgcccag
     4741 ctaattttgt attttagtag agacagggtt tctctatgtt ggtcaggctc gtctcgaact
     4801 cccgacctca gatgatccac ctgcctcggc ctcacaaagt gctaggatta caggcgtgag
     4861 ccactgcgcc cagtgatgtg aaggaatttc tttaacaaaa ctaaataggg cttattttta
     4921 tatttataga ttgtttatga cagtgctttc tagggactga gaattatacc gtatacagac
     4981 tcaccccaat ttaaaatttc ttccttcaaa cgttaaacct aatccacctc aatccctgac
     5041 acagtaactg aaagcttcaa atttttgaga ttaattcact tgttaatagt gaatttgaaa
     5101 ttacaagtgg taggttctga aatacatttt gaaatttttg aaaattaagg attttatgta
     5161 caataaattc tgtttgtaaa gatttatatt cagtctgtga agaggacagt attgcagact
     5221 tgagctaaat ataatcaatt ctgtgattag gaactcaaat tttagaagtt gatgacgtta
     5281 gtaaacttct aattgtcatt tgtgaaactt ccaattttcc ttgctgactt agctagttac
     5341 tgttactaag gcaagcattg aagagagtta actaagcatt cctatttgcc gtttccacac
     5401 aacaaaatgt gtctgtctcc tggatctttc tctgctctat gctgtttact tactggtaac
     5461 acccacttga caagtaaaga acctttgcat ggtcatcaca atgaaaggat aagttcttac
     5521 aagagtgaga atgctagagc aactattcct tttcaccttc tacagaaacc agtgactttc
     5581 gagtatgtgt accacaaaaa gttgtgtaag gagtgtattg agaatctccc atgactaagt
     5641 tgtctgagga agagttcagt aaatttgtat tcttcatgca aattgaagtc ctctgttttg
     5701 gtgctattgc ctctgagtat aaggaaggat ttgtgagtaa tcttatgttg aaacatagta
     5761 cttctggtaa tgattagaaa atatgtttag accacactta caagaatttc tctttattac
     5821 attagctttt ctttttgaat taattgaaga attcttaaat tgtcccactt atacgacata
     5881 gccaaagagt ttggatgatc atctttggtc taaattttca ctagcacttg aacagtcagt
     5941 gaagaatggc aagggtgagg accaaagggt gaactttgct tgcagtagtg catgtgcttt
     6001 cagaatcttg catgcaccct gtgatcttca cagttcctgc agctgatcaa ggtgtagaga
     6061 gggcaaatgg cacaaaatac tctaaataat ttcctgctgt ggttggtctt tggtttctga
     6121 gtgtcacctg gcttagctct ttcattacca ggcatttaga gagtaaaaat tagcacagga
     6181 taaacactgg gtttgccttc taaggtttaa ttactcatcc taataaaaga aagacatcct
     6241 tgaatctgtg cagagtatgt gaaacagagt cagggtaaag tatgtgaaac agaaggaact
     6301 ttgcttgctt gctttctgac atttggatta tccaaatgct ggcagacatc agaagcatta
     6361 tgtaaagtgt tctacaaatt tgttactcag aaataatttc gactctctta actaattgat
     6421 aaaattgaat ctatcataga aacttggctt tgtagaatcc aactccctca gaaaaagtta
     6481 ccaatttaag acgatgtttg aaaggttttg ttatagctta taaaacctag acaataaaaa
     6541 gactctctgt cttttctcta ggaagtcttt ttctctagca atttgtttaa agaactatca
     6601 gagtgatgaa ttctctatat ataggttgct tgtatgcatt caaatctcta gtctgctgaa
     6661 agctgtttac tcttctctgg gttcttagca tcaaatacgt aataagtcac caatgagtat
     6721 atttctgatt ctttcattga tcagttagtt catctggact aattggggaa aaagccaaag
     6781 ctaaataata gaaaattctg agtaaaaacc tttttatggg tatcatttgt aatttaaaag
     6841 tcaaagcaga aataaattaa gctaatagtt tatatcttac taggcattag aaaatatttt
     6901 tatgataact ataactagta gttatgtgta aatgagtgct gaattgaggt atttgaaagc
     6961 aacttatttt taagtaattt tatcatttac atatagtatt atatttatgt agaaaaaatt
     7021 ataaaaacgt ttattttatc cctttttaag ggatgtcaaa gtctatattc aaaaaattga
     7081 attaaccact atttgtgcct tgaatacatg ggaggcattt tttattgttt actttgagat
     7141 aagatagaaa cctctcagtt ttaaaaatat ttttcttaac agaggggata tctactcttt
     7201 ataaaaatca gtgattgcat aatttaaggt agtataaggc atgctaccaa tttataaaaa
     7261 ctaacctgtg ccttctatcc cagctgttct tacagaaatt aagtttcact ttctcatcag
     7321 gctatggttg agaagtatgt ctcatttata gtgccttctg tgatcttagg acatgtgact
     7381 aaacttgaat aaaagttaag gctgtatgac atttctggta ccttcatgat gcaaaattta
     7441 atcccacact accataaata gatggcagtg agatcttctg atctcataag tgtaattttt
     7501 atttatgaaa gattttagac ttatccacat tttattggaa agtgtttttg tgttctttgc
     7561 tttgatctgt agttgtgtaa tagaaaacaa acaacaaaaa agccagcata acaatatttt
     7621 agtaggttct tttccttaag tagatactgt aatttgcttt tagtggttgc attggggccg
     7681 gtggacttca ttgtatggta ttatttatta ggggtttagc aaacatctag atgtattcaa
     7741 atggctatgt cttagtatca gtgtgttttg agaataaact gtgttatgtt tgtttagctc
     7801 cccacatgct tttggagaat atacaattaa aaagcttaaa aaca
//
