LOCUS       XM_047442264            8169 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens THO complex subunit 2 (THOC2), transcript
            variant X2, mRNA.
ACCESSION   XM_047442264
VERSION     XM_047442264.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000023.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8169
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
     gene            1..8169
                     /gene="THOC2"
                     /gene_synonym="CXorf3; dJ506G2.1; hTREX120; MRX12; MRX35;
                     THO2; XLID12"
                     /note="THO complex subunit 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 64 ESTs, 1442 long SRA reads, 2 Proteins, and 95%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 68 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:57187"
                     /db_xref="HGNC:HGNC:19073"
                     /db_xref="MIM:300395"
     CDS             31..4971
                     /gene="THOC2"
                     /gene_synonym="CXorf3; dJ506G2.1; hTREX120; MRX12; MRX35;
                     THO2; XLID12"
                     /codon_start=1
                     /product="THO complex subunit 2 isoform X1"
                     /protein_id="XP_047298220.1"
                     /db_xref="GeneID:57187"
                     /db_xref="HGNC:HGNC:19073"
                     /db_xref="MIM:300395"
                     /translation="MAAAAVVVPAEWIKNWEKSGRGEFLHLCRILSENKSHDSSTYRD
                     FQQALYELSYHVIKGNLKHEQASNVLSDISEFREDMPSILADVFCILDIETNCLEEKS
                     KRDYFTQLVLACLYLVSDTVLKERLDPETLESLGLIKQSQQFNQKSVKIKTKLFYKQQ
                     KFNLLREENEGYAKLIAELGQDLSGSITSDLILENIKSLIGCFNLDPNRVLDVILEVF
                     ECRPEHDDFFISLLESYMSMCEPQTLCHILGFKFKFYQEPNGETPSSLYRVAAVLLQF
                     NLIDLDDLYVHLLPADNCIMDEHKREIAEAKQIVRKLTMVVLSSEKMDEREKEKEKEE
                     EKVEKPPDNQKLGLLEALLKIGDWQHAQNIMDQMPPYYAASHKLIALAICKLIHITIE
                     PLYRRVGVPKGAKGSPVNALQNKRAPKQAESFEDLRRDVFNMFCYLGPHLSHDPILFA
                     KVVRIGKSFMKEFQSDGSKQEDKEKTEVILSCLLSITDQVLLPSLSLMDCNACMSEEL
                     WGMFKTFPYQHRYRLYGQWKNETYNSHPLLVKVKAQTIDRAKYIMKRLTKENVKPSGR
                     QIGKLSHSNPTILFDYVCFEILSQIQKYDNLITPVVDSLKYLTSLNYDVLAYCIIEAL
                     ANPEKERMKHDDTTISSWLQSLASFCGAVFRKYPIDLAGLLQYVANQLKAGKSFDLLI
                     LKEVVQKMAGIEITEEMTMEQLEAMTGGEQLKAEGGYFGQIRNTKKSSQRLKDALLDH
                     DLALPLCLLMAQQRNGVIFQEGGEKHLKLVGKLYDQCHDTLVQFGGFLASNLSTEDYI
                     KRVPSIDVLCNEFHTPHDAAFFLSRPMYAHHISSKYDELKKSEKGSKQQHKVHKYITS
                     CEMVMAPVHEAVVSLHVSKVWDDISPQFYATFWSLTMYDLAVPHTSYEREVNKLKVQM
                     KAIDDNQEMPPNKKKKEKERCTALQDKLLEEEKKQMEHVQRVLQRLKLEKDNWLLAKS
                     TKNETITKFLQLCIFPRCIFSAIDAVYCARFVELVHQQKTPNFSTLLCYDRVFSDIIY
                     TVASCTENEASRYGRFLCCMLETVTRWHSDRATYEKECGNYPGFLTILRATGFDGGNK
                     ADQLDYENFRHVVHKWHYKLTKASVHCLETGEYTHIRNILIVLTKILPWYPKVLNLGQ
                     ALERRVHKICQEEKEKRPDLYALAMGVEVYLLPSGDYGRLCDHVSTGCYSGQLKSRKS
                     YMIPENEFHHKDPPPRNAVASVQNGPGGGPSSSSIGSASKSDESSTEETDKSRERSQC
                     GVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTPEARV
                     LGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESK
                     STQEREREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRR
                     KIDTHPSPSHSSTVKVTAILPKVPLGSENYASSPVISIHFLQDSLIELKESSAKLYIN
                     HTPPPLSKSKEREMDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPPDLTKR
                     RKEENGTMGVSKHKSESPCESPYPNEKDKEKNKSKSSGKEKGSDSFKSEKMDKISSGG
                     KKESRHDKEKIEKKEKRDSSGGKEEKKHHKSSDKHR"
     polyA_site      8169
                     /gene="THOC2"
                     /gene_synonym="CXorf3; dJ506G2.1; hTREX120; MRX12; MRX35;
                     THO2; XLID12"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 atccgggctt ctgctactag tgagaggaag atggcggccg cggctgtggt ggttcccgca
       61 gagtggataa agaactggga gaaatcaggg agaggcgaat ttttgcattt atgtcggatc
      121 ctcagtgaaa ataaaagcca tgatagttca acatacagag atttccagca agctctctat
      181 gagttgtcat atcatgtaat taaaggaaat ctaaagcatg aacaggcatc taatgttctt
      241 agtgacatta gtgaatttcg tgaggatatg ccctccattc ttgctgatgt attctgcata
      301 ttagacattg agacaaattg tttagaagaa aaaagcaaga gagactattt tacacagttg
      361 gtattagcat gtttgtattt agtttcagac acagttctaa aggaacgcct ggatccagaa
      421 acactggaat cattagggct tatcaaacaa tcacagcaat tcaatcaaaa gtcagttaaa
      481 atcaagacaa aactctttta taagcagcaa aaattcaatt tgttaagaga agagaatgaa
      541 ggttatgcca agctgattgc tgaattgggg caagatttat ctggaagtat tactagtgat
      601 ttaatcttag aaaatatcaa atctttaata ggatgcttta atctggatcc caatagagtt
      661 ttggatgtca ttttagaagt gtttgaatgc aggccagaac acgatgactt ctttatatct
      721 ttgttagaat cttacatgag tatgtgtgaa ccgcaaacac tgtgtcatat tcttgggttc
      781 aaattcaagt tttaccagga accaaatggc gagacaccat catctttata cagagttgca
      841 gcagtacttc tacaatttaa tcttattgat ttagatgatc tttatgtaca tcttcttccg
      901 gctgataatt gcattatgga tgaacacaaa cgagaaattg cggaagctaa gcaaattgtt
      961 agaaagctta cgatggttgt gttgtcttct gaaaaaatgg atgagcgaga gaaagaaaag
     1021 gaaaaagaag aggagaaagt agagaaacca cctgataacc aaaaacttgg cttgttggaa
     1081 gccttattaa agattggtga ttggcaacat gcacagaaca ttatggatca gatgcctcca
     1141 tactatgcag cttcacacaa gctaatagcc cttgctattt gcaagctcat tcatataact
     1201 attgagcctc tctaccgaag agttggagtt cctaaaggtg ctaaaggctc acctgttaat
     1261 gctttgcaaa acaagagagc accaaaacaa gctgagagct ttgaagattt gaggagagac
     1321 gtgttcaata tgttctgtta ccttggtcct cacctttctc acgatcccat tttatttgca
     1381 aaagtggtgc gcataggcaa gtcatttatg aaggagtttc agtctgatgg aagcaaacaa
     1441 gaagataaag aaaaaacgga agttatcctt agctgtttgc ttagcattac tgaccaggta
     1501 ctacttccat ctctttcttt gatggactgc aatgcttgta tgtctgagga actatgggga
     1561 atgtttaaaa catttccata tcagcataga tatcgtctgt atggccagtg gaagaatgaa
     1621 acttataaca gtcacccact tttagtaaaa gttaaagctc aaacaataga cagagccaaa
     1681 tatatcatga agcgcctaac caaggaaaat gtgaagcctt ctggaagaca aattgggaag
     1741 ttgagccaca gcaatccaac cattttgttt gattatgtat gttttgagat cttgtcacaa
     1801 atacagaagt atgataactt aataacacct gtagtagatt cattgaaata cctcacttca
     1861 ctgaattatg atgtcttggc ctattgtatc attgaagctt tagctaatcc agaaaaggaa
     1921 agaatgaaac atgatgacac aaccatctca agctggcttc agagtctggc tagtttctgt
     1981 ggtgcagttt ttcgtaaata tccaattgat cttgctggtc ttcttcagta tgttgccaat
     2041 cagctaaagg cgggcaaaag ttttgacctg cttatattga aagaagtggt acaaaaaatg
     2101 gcaggaatag aaattacaga ggaaatgaca atggagcaac tagaggctat gactggtgga
     2161 gagcagctaa aagctgaggg tggttatttt ggtcagatca gaaacactaa aaaatcctct
     2221 cagagattaa aggatgctct attggaccat gatcttgccc ttcctctctg tctgcttatg
     2281 gctcagcaga gaaatggggt aatctttcag gaaggtggag agaaacattt gaaacttgtg
     2341 ggaaagctct atgaccagtg tcatgatacc ctggtgcagt ttggtgggtt tttagcatct
     2401 aatctgagca cagaagatta tataaagcga gtgccttcaa ttgatgtact ctgtaatgaa
     2461 tttcatacac cccatgatgc agcatttttc ctgtctaggc caatgtatgc ccatcatatt
     2521 tcgtcaaagt atgatgaact taaaaaatca gaaaagggaa gtaaacagca acataaagtt
     2581 cataagtaca ttacatcatg tgagatggtg atggcgcctg tccatgaagc agtggtctcc
     2641 ttacatgttt ccaaagtctg ggatgacatc agccctcaat tctatgctac attctggtca
     2701 ttgacaatgt atgaccttgc agttccacac accagctatg aacgagaagt caataaactt
     2761 aaagtccaga tgaaagcaat tgatgacaat caggaaatgc ccccaaataa aaagaaaaaa
     2821 gagaaggagc gctgtactgc ccttcaggac aagcttcttg aagaagaaaa gaaacagatg
     2881 gaacatgtac agagagttct acagagattg aaactggaaa aggacaactg gcttttagca
     2941 aaatctacca aaaatgagac catcacaaaa tttctacagc tgtgtatatt tcctcgatgt
     3001 attttttcag caattgatgc tgtttactgt gctcgttttg ttgaattggt acatcaacag
     3061 aaaactccaa atttttccac acttctttgc tatgatcgag ttttctctga cataatttac
     3121 acagttgcaa gctgtactga aaatgaagcc agtcgatacg gaaggtttct ttgctgcatg
     3181 ttagagactg tgaccaggtg gcatagtgat agagccacat atgaaaagga atgtggaaac
     3241 tatccaggat tccttaccat attacgggca actggatttg atggtggaaa taaggctgat
     3301 caattagact atgaaaattt tcgacatgtt gtacataaat ggcattacaa actaaccaag
     3361 gcatcggtac attgccttga aacaggcgaa tatactcaca tcaggaatat cttgattgtg
     3421 ctaacaaaaa tacttccttg gtacccaaaa gttttgaatc tgggtcaagc tttggaaaga
     3481 agagtacaca aaatctgcca agaagaaaaa gagaagaggc cagatctata tgcattggct
     3541 atgggtgttg aagtttatct tctgccttca ggagattatg ggagattatg cgatcatgtt
     3601 tccacaggct gctactctgg gcagttgaaa agtagaaagt catacatgat acctgaaaat
     3661 gagtttcatc acaaagaccc ccctccgagg aatgcagttg ccagtgtgca aaatgggcct
     3721 ggtggtgggc cttcttcatc atcaatagga agtgcatcta aatcggatga aagcagtact
     3781 gaggagactg ataaatcaag ggagagatct cagtgtggtg tgaaagctgt taataaagct
     3841 tctagtacca cacctaaagg gaattcaagc aatggaaata gtggctctaa cagcaacaaa
     3901 gctgttaaag aaaatgacaa agaaaaaggg aaagagaaag aaaaagagaa aaaagaaaag
     3961 actccagcta ctactccaga ggccagggta cttggtaaag atggtaaaga aaaaccaaag
     4021 gaagagcggc caaataaaga tgaaaaagca agagagacca aggaaagaac gccgaagtct
     4081 gacaaagaga aagaaaaatt caagaaggaa gaaaaagcta aagatgagaa atttaagacc
     4141 actgtcccca acgcagaatc aaaatcaact caagaaaggg aaagagagaa ggagccatcc
     4201 agagaaagag atatagcaaa ggaaatgaaa tcaaaggaaa atgttaaagg aggagaaaaa
     4261 acaccagttt ctgggtcctt gaaatcacct gttcccagat cagatattcc agagcctgaa
     4321 agggaacaaa aacgccgcaa aattgatact cacccttctc catcacattc ctccacagta
     4381 aaggttacag ccatacttcc caaagttcct ctgggttctg agaactatgc cagctcacct
     4441 gtcatctcca ttcattttct acaggacagt ctcatcgaac tcaaggaatc ttcagcaaag
     4501 ctctacatta atcatactcc tccaccactg tccaagagta aggagagaga aatggacaag
     4561 aaagatttgg acaagtcaag ggaaagatcc agagaaagag agaaaaaaga tgaaaaggac
     4621 aggaaagagc ggaaaaggga tcactcaaac aacgaccgtg aagtgccacc ggacttaacc
     4681 aagagacgta aagaggagaa tggaacaatg ggggtttcaa aacataaaag tgaaagtcct
     4741 tgtgaatctc cttatccaaa tgagaaagac aaggaaaaaa ataagtcaaa atcttcaggc
     4801 aaagaaaaag gcagtgattc atttaaatct gagaagatgg ataaaatctc ctccggtggc
     4861 aaaaaggagt ccaggcatga taaagaaaag atagaaaaga aagagaaacg ggacagttca
     4921 ggaggaaagg aagagaagaa acatcataag tcctcggaca agcacagata atgaagactt
     4981 tccatcaagg ctatggacag accccctaag ccgaaagtct cccagaggag gatgccaaag
     5041 ctccgtgcgt cactctcaga atgatatctc ccataattaa gagcttctgg tgctgtccat
     5101 ttaatgggaa tctgctttaa gtcagaagat gagtacacac caccatcctc ttgacgagac
     5161 attccaaagt cactgatttt cagaacatta ttttcacctc caggcagttt cttacagcaa
     5221 ggtccctgtg tatacatttt ttactcgaga tacaccatcc agaatcagca tctaatgaaa
     5281 atttcactga gttttagttc attcttcttt ctctgaaagg agaggaaatc gcctccagga
     5341 accagttcct taatgacgta gataggccgt ctttgtgtgt gaactcctat acttttgaca
     5401 ttactgggat gattatattg cttgaggatt ttggcttcta gtaaaaattt taatttcagt
     5461 tcctggggaa gacgttcttg acgtgtttta acagcaacag caattttatc ctttaatgtg
     5521 accttaaatg tgtcaccaaa atttcccttg cctcttgtaa cgtggcacct ttatgattga
     5581 gaacccattt cttattctcc taatggccat actgtgatac catgatgctc ttaattggaa
     5641 cattgacttt tttttttttt gcaatttaaa caattgagat aaaattcata taacatcaaa
     5701 tttacctttc actttttttt ttttcttttg gagaccaagt ctcgctgttg tctcccaggc
     5761 tggagtgcag tggcgcgatc tcggctcact gtgacctccg cctcctgggt tcaagcaatt
     5821 ctccttcctc agcctcctga gtagctggga ctacaggcgt gcaccaccac gcctggctaa
     5881 tttttgtatt tttagtagag ataggggttt caccgtgtta gccaggatgg tctcgatctc
     5941 ctgacctggt gatccacctg cctcggcctc ccaaagtgtt gggattataa gcgtgagcca
     6001 tgacgcctgg cctcaaactt gccattttta aagtgtacaa ttcaatggtt tttagtatat
     6061 ccactatgtt gtgcaagcat caccgctgtc taattccaga gcatttctgt caccccaaaa
     6121 agaaactcca tgcctattag cagtcactcc cagttcttcc cttcctcggc ccctggaaac
     6181 cagtaatgta ctttctgtct ctgtgatttt gcctgttttg gacatttcat ttaaatggaa
     6241 ttatgcaata atttgtggcc ttttgtgttt ggctttcact tagcatcatg ttctcaaggc
     6301 tcatccatgt tgtggcatgt atcagtactg cattcctttt tatggctaaa tgatgtttca
     6361 ttgtatgagt gtgtaccaca ttttatttat ccattcagca attaatggac aggaacaatg
     6421 gcttttaagt attaaattgt aagttcaaca ttaaatgtat ccacagttat tgataatatc
     6481 aagattatac atggtgtgaa cagaatgctg tgtcgaaatg gtatgtaaat tatttgtcag
     6541 catttcatgt aagtgattat tttctaagga cccttctagc cctggtttta agaaatatgt
     6601 gaatgtagta ttttcatcaa taaagtttaa tgcattaagc attagcttaa aatttgaatg
     6661 aaggcagatg tgaagatatt tgccacatgt tgtaataatc atgttttgaa attatttcaa
     6721 tatgaagtat ttgaaaaatg tcaatacata aaggaaagga aatgagtata attaagtcaa
     6781 tatattttta aagcaatttt tataatttag cagacactgc atcttaatat aagttactat
     6841 taaaattgtg tccttgtgaa aaatgtgatg tcattttcct ttttttgttg atcatgtaaa
     6901 ataggttact tttctttgct acattttcta tttaataagc tattgcttgc cgttgtggaa
     6961 tgttttactt gttgctccat ttttttctcc ctacccccac ccctctctcc cacacgcaca
     7021 caatgttcaa tttttttttt aagtcatcat tagtgtgttt atctttaatg gattctaaga
     7081 atggacaaaa agaaacacac aaatatttca tccttttctg gggactcaag tctttgttac
     7141 cgatggaact cattaacttc ttgttctttc ttaaatcttc ctccctcctt accttttcct
     7201 ctccttcctt ctcttcttct tcctttcttc tcccctccct ccctccctcc cttcttccct
     7261 ccctcctcct ttcattctcc ttctctcctt ctcccttcct tttctcctac ctcctttgac
     7321 taagcctccc tcccctactc cctcctttcc ttccttcctt ccttcttctc tatcaatata
     7381 atcactttgt ttctttcagg tgagatcgga ctggaactgt tcggctgcga ccagaaattt
     7441 attttcctga gtaaattgcc gagaattaag aatgaagagg gccatttgca tctccttaaa
     7501 ttattcagtt acctgcttta ttgctccatg tggaaaactt aaaattgtta agttgtgcat
     7561 tactgtattt taacttgttg cttagtttct acatgtttat tttcagtaat ggctgaaagt
     7621 gttaactgtt ccatactttt agcacaatgt gctgcataag gttacctgtg tacagagttt
     7681 tactttagat taactaaata ttgcctgggt tcagttttta tttccattct gaaatgcttc
     7741 ctttttattg tttgaaactg aaaataaaca attgttgaac ccttttgatt ttacctcatt
     7801 ttaaaactgt tttaatttat tatttggctt gttcttaata ttagtcacta aaagcagtgg
     7861 gagcattgtc ttatgaaatg cttaggaatc attttatata gtacatgtac aacattaaac
     7921 gtgtttaaaa aagaaaaagg taccagcgat cacttgtccc ttgccatttt ttcttgtaat
     7981 tatgttagac aaatcttggc ggcgggggga tcaaaacata attgttttaa ttctacagct
     8041 gtaggagctt tgtattgctg aactttcatc tggaaaagtt tcacagtgac atttttaaaa
     8101 gagaattttt ttatctgccg aattctacca gtgtaacctt ttttctaaat aaacaatagt
     8161 tttctcaaa
//
