LOCUS       XM_006710867            6187 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transforming growth factor beta receptor 3
            (TGFBR3), transcript variant X1, mRNA.
ACCESSION   XM_006710867
VERSION     XM_006710867.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006710867.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6187
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..6187
                     /gene="TGFBR3"
                     /gene_synonym="betaglycan; BGCAN"
                     /note="transforming growth factor beta receptor 3; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 38 ESTs, 797 long SRA reads, 3 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 109 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:7049"
                     /db_xref="HGNC:HGNC:11774"
                     /db_xref="MIM:600742"
     CDS             236..2791
                     /gene="TGFBR3"
                     /gene_synonym="betaglycan; BGCAN"
                     /codon_start=1
                     /product="transforming growth factor beta receptor type 3
                     isoform X1"
                     /protein_id="XP_006710930.1"
                     /db_xref="GeneID:7049"
                     /db_xref="HGNC:HGNC:11774"
                     /db_xref="MIM:600742"
                     /translation="MTSHYVIAIFALMSSCLATAGPEPGALCELSPVSASHPVQALME
                     SFTVLSGCASRGTTGLPQEVHVLNLRTAGQGPGQLQREVTLHLNPISSVHIHHKSVVF
                     LLNSPHPLVWHLKTERLATGVSRLFLVSEGSVVQFSSANFSLTAETEERNFPHGNEHL
                     LNWARKEYGAVTSFTELKIARNIYIKVGEDQVFPPKCNIGKNFLSLNYLAEYLQPKAA
                     EGCVMSSQPQNEEVHIIELITPNSNPYSAFQVDITIDIRPSQEDLEVVKNLILILKCK
                     KSVNWVIKSFDVKGSLKIIAPNSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDN
                     GYSPITSYTMAPVANRFHLRLENNAEEMGDEEVHTIPPELRILLDPGALPALQNPPIR
                     GGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDI
                     ALSVKCDNEKMIVAVEKDSFQASGYSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTR
                     PRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDASLFTRPE
                     IVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVS
                     VTKAEQELGFAIQTCFISPYSNPDRMSHYTIIENICPKDESVKFYSPKRVHFPIPQAD
                     MDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEACTSLDASIIWA
                     MMQNKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIG
                     ALLTGALWYIYSHTGETAGRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA"
ORIGIN      
        1 aatcgagggt ttcggggacg ccgagcggca ctttcctctt cccagcgagt gaaggagggc
       61 agtcggcggc tctcgcgccc cggccacttt ccctgcgcga ttcccggagc tccctgcagg
      121 aggcagtttg aaaattgcaa ggagggactt taagactact tctgatttgc aaagattgtc
      181 tgtgctctga gcaggctgaa gtgactggac gagacgcact gttggagaaa taaaaatgac
      241 ttcccattat gtgattgcca tctttgccct gatgagctcc tgtttagcca ctgcaggtcc
      301 agagcctggt gcactgtgtg aactgtcacc tgtcagtgcc tcccatcctg tccaggcctt
      361 gatggagagc ttcactgttt tgtcaggctg tgccagcaga ggcacaactg ggctgccaca
      421 ggaggtgcat gtcctgaatc tccgcactgc aggccagggg cctggccagc tacagagaga
      481 ggtcacactt cacctgaatc ccatctcctc agtccacatc caccacaagt ctgttgtgtt
      541 cctgctcaac tccccacacc ccctggtgtg gcatctgaag acagagagac ttgccactgg
      601 ggtctccaga ctgtttttgg tgtctgaggg ttctgtggtc cagttttcat cagcaaactt
      661 ctccttgaca gcagaaacag aagaaaggaa cttcccccat ggaaatgaac atctgttaaa
      721 ttgggcccga aaagagtatg gagcagttac ttcattcacc gaactcaaga tagcaagaaa
      781 catttatatt aaagtggggg aagatcaagt gttccctcca aagtgcaaca tagggaagaa
      841 ttttctctca ctcaattacc ttgctgagta ccttcaaccc aaagcagcag aagggtgtgt
      901 gatgtccagc cagccccaga atgaggaagt acacatcatc gagctaatca cccccaactc
      961 taacccctac agtgctttcc aggtggatat aacaattgat ataagacctt ctcaagagga
     1021 tcttgaagtg gtcaaaaatc tcatcctgat cttgaagtgc aaaaagtctg tcaactgggt
     1081 gatcaaatct tttgatgtta agggaagcct gaaaattatt gctcctaaca gtattggctt
     1141 tggaaaagag agtgaaagat ctatgacaat gaccaaatca ataagagatg acattccttc
     1201 aacccaaggg aatctggtga agtgggcttt ggacaatggc tatagtccaa taacttcata
     1261 cacaatggct cctgtggcta atagatttca tcttcggctt gaaaataatg cagaggagat
     1321 gggagatgag gaagtccaca ctattcctcc tgagctacgg atcctgctgg accctggtgc
     1381 cctgcctgcc ctgcagaacc cgcccatccg gggaggggaa ggccaaaatg gaggccttcc
     1441 gtttcctttc ccagatattt ccaggagagt ctggaatgaa gagggagaag atgggctccc
     1501 tcggccaaag gaccctgtca ttcccagcat acaactgttt cctggtctca gagagccaga
     1561 agaggtgcaa gggagcgtgg atattgccct gtctgtcaaa tgtgacaatg agaagatgat
     1621 cgtggctgta gaaaaagatt cttttcaggc cagtggctac tcggggatgg acgtcaccct
     1681 gttggatcct acctgcaagg ccaagatgaa tggcacacac tttgttttgg agtctcctct
     1741 gaatggctgc ggtactcggc cccggtggtc agcccttgat ggtgtggtct actataactc
     1801 cattgtgata caggttccag cccttgggga cagtagtggt tggccagatg gttatgaaga
     1861 tctggagtca ggtgataatg gatttccggg agatatggat gaaggagatg cttccctgtt
     1921 cacccgacct gaaatcgtgg tgtttaattg cagccttcag caggtgagga accccagcag
     1981 cttccaggaa cagccccacg gaaacatcac cttcaacatg gagctataca acactgacct
     2041 ctttttggtg ccctcccagg gcgtcttctc tgtgccagag aatggacacg tttatgttga
     2101 ggtatctgtt actaaggctg aacaagaact gggatttgcc atccaaacgt gctttatctc
     2161 tccatattcg aaccctgata ggatgtctca ttacaccatt attgagaata tttgtcctaa
     2221 agatgaatct gtgaaattct acagtcccaa gagagtgcac tttcctatcc cgcaagctga
     2281 catggataag aagcgattca gctttgtctt caagcctgtc ttcaacacct cactgctctt
     2341 tctacagtgt gagctgacgc tgtgtacgaa gatggagaag cacccccaga agttgcctaa
     2401 gtgtgtgcct cctgacgaag cctgcacctc gctggacgcc tcgataatct gggccatgat
     2461 gcagaataag aagacgttca ctaagcccct tgctgtgatc caccatgaag cagaatctaa
     2521 agaaaaaggt ccaagcatga aggaaccaaa tccaatttct ccaccaattt tccatggtct
     2581 ggacacccta accgtgatgg gcattgcgtt tgcagccttt gtgatcggag cactcctgac
     2641 gggggccttg tggtacatct attctcacac aggggagaca gcaggaaggc agcaagtccc
     2701 cacctccccg ccagcctcgg aaaacagcag tgctgcccac agcatcggca gcacgcagag
     2761 cacgccttgc tccagcagca gcacggccta gcccaaccca gcccaacccg gcccaaccca
     2821 gcccagccca gctcagctca gctactgcca agggcaggac caatggctga gcctcgtgtc
     2881 cagactcaga gggctggatt ttggttccct tgtaaagaca gagtgaattt cagtataaag
     2941 atcacccgtt gtattcaccc cacacccagg gctagtataa acatgaccct gggcttctgt
     3001 accacactag aattcatgtg agaaagctaa aatggtggtc ttctccacca gcccctcaca
     3061 ggcttggggg ttttcaatgt gaaacacatg ccagttttta aaatgctgct ttgtccaggt
     3121 gagaacatcc ataatttggg gccctgagtt ttacccagac tcaaggagtt ggtaaagggt
     3181 taatagccag atagtagaac cagtgaggag atgcggccaa agattcttta tatctgaacc
     3241 aagatgtaaa acaagaaatg ctttgaggct ttctaagcga tcctcctgtc taatttgcac
     3301 ctttgtctgg atgcacactt ctgaccttgc tgccacaacc tgtggggtct gatgtgtccc
     3361 ttgatgggtg ctgccctcag ggactgcacc ctgacaagtg ttaaggcaac attcctttct
     3421 tgtgccctgg gccaaaacca atgctgatga ccttatcagc ttcctgtttc ttcccatact
     3481 tgcatacacc actgcaaaat gtcttaatgc aaattttgta tttcttacag gcctacagaa
     3541 attgaaaatg accaaaatca ggaaccacag atttgtgccc attcctaata ttttgttctg
     3601 caaattaatg tataatttga ggtgaaattc agttataaag tcaaggacga atttgcacag
     3661 tgatatattt ctatgtgtat gcaagtacaa gtatataata tgtcacctgg cacattcatt
     3721 ttctcagttg aagaagagaa aatttgaaaa tgtccttatg cttttagagt tgcaacttaa
     3781 gtatatttgg tagggtgagt gtttccactc aaaatatgtc aacttaaaaa aaaataggcc
     3841 ctttcataaa aaccaaactg tagcaagatg caaatgcatg gcaaatcctg tcggtctcca
     3901 gttggttatc tgaatagtgt caccaattcc accaagacag tgctgagatt ggaaaagggc
     3961 actcatttgg attgccttac ttctcttgcc ttaaatatat cccatatatt taatatgtca
     4021 aaaagggctt gaggtgaatt tcattaaatg gaataatatg atgccacttt gcagctaaaa
     4081 taagctcagt gatacctcct tgttaaaaaa aaaaaaaaaa aaaaagaatg ccagggggga
     4141 attatcatgc taaattattt tactgctgaa gatagcttca ttgcaaatta ttctttttcc
     4201 agaatttccc ccaaacaact tagaattcca taagtagaac aagatagatt ctacccccaa
     4261 aatattcata agcaaatccc actgccctta aaataaggaa gttatgcctg gttgtctgtg
     4321 aatggaacct cagtaggtaa tcctgatgaa gcttaaaacc ttagggcagt gtctacatgg
     4381 gaaacaagta tgtggaaatt gacaatcatt tttaccaaat cgttgagtaa taatatgact
     4441 tacctgatag atatacacat tcaataagga acattttttt ttttcaataa ggaacatttt
     4501 aactaaaaca ttactttagg gctgagattt ccaggctatc tacattgatc tactgaaaaa
     4561 tttctagatt tccatataca aacgaagaag acatgagttt agagaatttt tttcctttaa
     4621 ttttttttta acagaagggt atcagagtgg aggacctaga ttacgctacc tgtgtttgaa
     4681 aatattgcgc tttgcctaac cttcggtgga atgtattgtt tcagcatatt ctatgtataa
     4741 aaaagtttaa agatgtcttc aaagaagact agagtcttta agtcacttat agctatattt
     4801 tactacaaaa tttgtgtata aagatatatt taagtgtttt agataaattt aagttactcc
     4861 atatgaaatg tttaatttca gctactgtga attctttcga tcagtccttt gcttttttaa
     4921 aaaatctttt ccatcgtgtt aaaaagaaaa ttagctatta ggagatatta aaagattgat
     4981 gtcttagaag gacagggtta aaaccttctg taatatattt aaatatatat ttttaagaga
     5041 gatgctacat tgccaatgat tttataaata atttaaaatt aatttacaaa tttatagatg
     5101 caaaccaaaa gatcttttta aaagagagag agaggaaaaa aatcaccttt tatttgtttg
     5161 ggtctcattg tcagaattat tattcagatc aagaaatctg tgtcgataaa acctaatctc
     5221 atattggaga gtgaatgtcg ttaagtattt ctgaaatgtt tctaaaaaat gaacatgaaa
     5281 aaaataaggt attttctccc tagcttctca ttacagtatt tctaattgct tcacacttta
     5341 cagttttaat acaaagtaca agctctactt ttataacgtg tactacaagt ttctttaaaa
     5401 gtattgttgt atttcagctg aactcttgta tctgcagtct tttgttattt ctgcaggcta
     5461 cacccttaat ttgcagaggc cattttgttg tttgtttgat gctgaagctg ttgttaaaat
     5521 gccccaaact ccaaggcaga ttgtctgtat aatacgctat agcttttcac catgtggtgt
     5581 ttaccagctg ttactctgta ttttaaaaag ccagagattt cttctgtcta aactgtttct
     5641 atagcatttt ctaaacaaaa aaaatggttt ttttctttgc cttgtaataa gattgtaaat
     5701 ccatttcctg cttgtgttct tagtgggcat gattgtgagt gtgtgtgggg tgctcacacg
     5761 cgtgccagtc tttttgtact gtaactacct catggtttga atgatgattg tactgctggt
     5821 tgtgttaaca gagcacattt tgttgggtga gtcctatgtg atttttttca tgtttgtttt
     5881 atctgggggt tgttcatgaa actgacagat gtttttctaa aaaggactat tatcagtttc
     5941 caaatacaat acttctctct tctggttttt cctgaatgag cctgattttg ttgctggttt
     6001 tcatcatcta tgagggtaaa acgagtaccc ttaaaatccc tgtggccagt ttgaacaccc
     6061 ctgttgtatt cttttctctg ttcagtgtgt cagctatttt gtgaagatgc ttagatgtat
     6121 agttttgata accacagttt taaatctttt atctgtgcat aataaaaaga tatatatcag
     6181 ttattaa
//
