LOCUS       XM_047448786            4341 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transferrin receptor (TFRC), transcript
            variant X1, mRNA.
ACCESSION   XM_047448786
VERSION     XM_047448786.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4341
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4341
                     /gene="TFRC"
                     /gene_synonym="CD71; IMD46; p90; T9; TFR; TFR1; TR; TRFR"
                     /note="transferrin receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 132
                     ESTs, 7138 long SRA reads, 2 Proteins, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 45 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:7037"
                     /db_xref="HGNC:HGNC:11763"
                     /db_xref="MIM:190010"
     CDS             247..1683
                     /gene="TFRC"
                     /gene_synonym="CD71; IMD46; p90; T9; TFR; TFR1; TR; TRFR"
                     /codon_start=1
                     /product="transferrin receptor protein 1 isoform X1"
                     /protein_id="XP_047304742.1"
                     /db_xref="GeneID:7037"
                     /db_xref="HGNC:HGNC:11763"
                     /db_xref="MIM:190010"
                     /translation="MDQTKFPIVNAELSFFGHAHLGTGDPYTPGFPSFNHTQFPPSRS
                     SGLPNIPVQTISRAAAEKLFGNMEGDCPSDWKTDSTCRMVTSESKNVKLTVSNVLKEI
                     KILNIFGVIKGFVEPDHYVVVGAQRDAWGPGAAKSGVGTALLLKLAQMFSDMVLKDGF
                     QPSRSIIFASWSAGDFGSVGATEWLEGYLSSLHLKAFTYINLDKAVLGTSNFKVSASP
                     LLYTLIEKTMQNVKHPVTGQFLYQDSNWASKVEKLTLDNAAFPFLAYSGIPAVSFCFC
                     EDTDYPYLGTTMDTYKELIERIPELNKVARAAAEVAGQFVIKLTHDVELNLDYERYNS
                     QLLSFVRDLNQYRADIKEMGLSLQWLYSARGDFFRATSRLTTDFGNAEKTDRFVMKKL
                     NDRVMRVEYHFLSPYVSPKESPFRHVFWGSGSHTLPALLENLKLRKQNNGAFNETLFR
                     NQLALATWTIQGAANALSGDVWDIDNEF"
ORIGIN      
        1 gttgtatgtt gaaaatcaat ttcgtgaatt taaactcagc aaagtctggc gtgatcaaca
       61 ttttgttaag attcaggtca aagacagggt aaactggtcc atgctaattt tggtactaaa
      121 aaagattttg aggatttata cactcctgtg aatggatcta tagtgattgt cagagcaggg
      181 aaaatcacct ttgcagaaaa ggttgcaaat gctgaaagct taaatgcaat tggtgtgttg
      241 atatacatgg accagactaa atttcccatt gttaacgcag aactttcatt ctttggacat
      301 gctcatctgg ggacaggtga cccttacaca cctggattcc cttccttcaa tcacactcag
      361 tttccaccat ctcggtcatc aggattgcct aatatacctg tccagacaat ctccagagct
      421 gctgcagaaa agctgtttgg gaatatggaa ggagactgtc cctctgactg gaaaacagac
      481 tctacatgta ggatggtaac ctcagaaagc aagaatgtga agctcactgt gagcaatgtg
      541 ctgaaagaga taaaaattct taacatcttt ggagttatta aaggctttgt agaaccagat
      601 cactatgttg tagttggggc ccagagagat gcatggggcc ctggagctgc aaaatccggt
      661 gtaggcacag ctctcctatt gaaacttgcc cagatgttct cagatatggt cttaaaagat
      721 gggtttcagc ccagcagaag cattatcttt gccagttgga gtgctggaga ctttggatcg
      781 gttggtgcca ctgaatggct agagggatac ctttcgtccc tgcatttaaa ggctttcact
      841 tatattaatc tggataaagc ggttcttggt accagcaact tcaaggtttc tgccagccca
      901 ctgttgtata cgcttattga gaaaacaatg caaaatgtga agcatccggt tactgggcaa
      961 tttctatatc aggacagcaa ctgggccagc aaagttgaga aactcacttt agacaatgct
     1021 gctttccctt tccttgcata ttctggaatc ccagcagttt ctttctgttt ttgcgaggac
     1081 acagattatc cttatttggg taccaccatg gacacctata aggaactgat tgagaggatt
     1141 cctgagttga acaaagtggc acgagcagct gcagaggtcg ctggtcagtt cgtgattaaa
     1201 ctaacccatg atgttgaatt gaacctggac tatgagaggt acaacagcca actgctttca
     1261 tttgtgaggg atctgaacca atacagagca gacataaagg aaatgggcct gagtttacag
     1321 tggctgtatt ctgctcgtgg agacttcttc cgtgctactt ccagactaac aacagatttc
     1381 gggaatgctg agaaaacaga cagatttgtc atgaagaaac tcaatgatcg tgtcatgaga
     1441 gtggagtatc acttcctctc tccctacgta tctccaaaag agtctccttt ccgacatgtc
     1501 ttctggggct ccggctctca cacgctgcca gctttactgg agaacttgaa actgcgtaaa
     1561 caaaataacg gtgcttttaa tgaaacgctg ttcagaaacc agttggctct agctacttgg
     1621 actattcagg gagctgcaaa tgccctctct ggtgacgttt gggacattga caatgagttt
     1681 taaatgtgat acccatagct tccatgagaa cagcagggta gtctggtttc tagacttgtg
     1741 ctgatcgtgc taaattttca gtagggctac aaaacctgat gttaaaattc catcccatca
     1801 tcttggtact actagatgtc tttaggcagc agcttttaat acagggtaga taacctgtac
     1861 ttcaagttaa agtgaataac cacttaaaaa atgtccatga tggaatattc ccctatctct
     1921 agaattttaa gtgctttgta atgggaactg cctctttcct gttgttgtta atgaaaatgt
     1981 cagaaaccag ttatgtgaat gatctctctg aatcctaagg gctggtctct gctgaaggtt
     2041 gtaagtggtc gcttactttg agtgatcctc caacttcatt tgatgctaaa taggagatac
     2101 caggttgaaa gaccttctcc aaatgagatc taagcctttc cataaggaat gtagctggtt
     2161 tcctcattcc tgaaagaaac agttaacttt cagaagagat gggcttgttt tcttgccaat
     2221 gaggtctgaa atggaggtcc ttctgctgga taaaatgagg ttcaactgtt gattgcagga
     2281 ataaggcctt aatatgttaa cctcagtgtc atttatgaaa agaggggacc agaagccaaa
     2341 gacttagtat attttctttt cctctgtccc ttcccccata agcctccatt tagttctttg
     2401 ttatttttgt ttcttccaaa gcacattgaa agagaaccag tttcaggtgt ttagttgcag
     2461 actcagtttg tcagacttta aagaataata tgctgccaaa ttttggccaa agtgttaatc
     2521 ttaggggaga gctttctgtc cttttggcac tgagatattt attgtttatt tatcagtgac
     2581 agagttcact ataaatggtg tttttttaat agaatataat tatcggaagc agtgccttcc
     2641 ataattatga cagttatact gtcggttttt tttaaataaa agcagcatct gctaataaaa
     2701 cccaacagat actggaagtt ttgcatttat ggtcaacact taagggtttt agaaaacagc
     2761 cgtcagccaa atgtaattga ataaagttga agctaagatt tagagatgaa ttaaatttaa
     2821 ttaggggttg ctaagaagcg agcactgacc agataagaat gctggttttc ctaaatgcag
     2881 tgaattgtga ccaagttata aatcaatgtc acttaaaggc tgtggtagta ctcctgcaaa
     2941 attttatagc tcagtttatc caaggtgtaa ctctaattcc cattttgcaa aatttccagt
     3001 acctttgtca caatcctaac acattatcgg gagcagtgtc ttccataatg tataaagaac
     3061 aaggtagttt ttacctacca cagtgtctgt atcggagaca gtgatctcca tatgttacac
     3121 taagggtgta agtaattatc gggaacagtg tttcccataa ttttcttcat gcaatgacat
     3181 cttcaaagct tgaagatcgt tagtatctaa catgtatccc aactcctata attccctatc
     3241 ttttagtttt agttgcagaa acattttgtg gtcattaagc attgggtggg taaattcaac
     3301 cactgtaaaa tgaaattact acaaaatttg aaatttagct tgggtttttg ttacctttat
     3361 ggtttctcca ggtcctctac ttaatgagat agtagcatac atttataatg tttgctattg
     3421 acaagtcatt ttaactttat cacattattt gcatgttacc tcctataaac ttagtgcgga
     3481 caagttttaa tccagaattg accttttgac ttaaagcaga gggactttgt atagaaggtt
     3541 tgggggctgt ggggaaggag agtcccctga aggtctgaca cgtctgccta cccattcgtg
     3601 gtgatcaatt aaatgtaggt atgaataagt tcgaagctcc gtgagtgaac catcattata
     3661 aacgtgatga tcagctgttt gtcatagggc agttggaaac ggcctcctag ggaaaagttc
     3721 atagggtctc ttcaggttct tagtgtcact tacctagatt tacagcctca cttgaatgtg
     3781 tcactactca cagtctcttt aatcttcagt tttatcttta atctcctctt ttatcttgga
     3841 ctgacattta gcgtagctaa gtgaaaaggt catagctgag attcctggtt cgggtgttac
     3901 gcacacgtac ttaaatgaaa gcatgtggca tgttcatcgt ataacacaat atgaatacag
     3961 ggcatgcatt ttgcagcagt gagtctcttc agaaaaccct tttctacagt tagggttgag
     4021 ttacttccta tcaagccagt acgtgctaac aggctcaata ttcctgaatg aaatatcaga
     4081 ctagtgacaa gctcctggtc ttgagatgtc ttctcgttaa ggagatgggc cttttggagg
     4141 taaaggataa aatgaatgag ttctgtcatg attcactatt ctagaacttg catgaccttt
     4201 actgtgttag ctctttgaat gttcttgaaa ttttagactt tctttgtaaa caaatgatat
     4261 gtccttatca ttgtataaaa gctgttatgt gcaacagtgt ggagattcct tgtctgattt
     4321 aataaaatac ttaaacactg a
//
