LOCUS       XM_011515963            6888 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens transcription factor EC (TFEC), transcript
            variant X1, mRNA.
ACCESSION   XM_011515963
VERSION     XM_011515963.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011515963.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6888
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..6888
                     /gene="TFEC"
                     /gene_synonym="bHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L;
                     TFECL"
                     /note="transcription factor EC; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 7 ESTs, 85 long SRA reads, 3 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 23 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:22797"
                     /db_xref="HGNC:HGNC:11754"
                     /db_xref="MIM:604732"
     CDS             176..1489
                     /gene="TFEC"
                     /gene_synonym="bHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L;
                     TFECL"
                     /codon_start=1
                     /product="transcription factor EC isoform X1"
                     /protein_id="XP_011514265.1"
                     /db_xref="GeneID:22797"
                     /db_xref="HGNC:HGNC:11754"
                     /db_xref="MIM:604732"
                     /translation="MLQALTGLQFQLKEQLGEKERRLQISQEISAHRTEFHMQFSYKP
                     VLHRLVPARPQIYSSQLPSFTRVPAHLESSARPQLQKAQRQKVNSFMTLDHQIINPTL
                     KWSQPAVPSGGPLVQHAHTTLDSDAGLTENPLTKLLAIGKEDDNAQWHMEDVIEDIIG
                     MESSFKEEGADSPLLMQRTLSGSILDVYSGEQGISPINMGLTSASCPSSLPMKREITE
                     TDTRALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASV
                     EYIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELEIQARTHGLPTLASLGTVDLG
                     AHVTKQQSHPEQNSVDYCQQLTVSQGPSPELCDQAIAFSDPLSYFTDLSFSAALKEEQ
                     RLDGMLLDDTISPFGTDPLLSATSPAVSKESSRRSSFSSDDGDEL"
ORIGIN      
        1 gaaaaagagg agaagtggga gtaaacagaa agataatgct tatggtacat acaaaacaaa
       61 tggagagatt gagtctcacg gattcttcgc ctgagccacc agcaaagagt cctatcaatg
      121 atttagttcc ctagagaaaa tcagaaagta aaagtgagaa gaaaagaaga gaaatatgtt
      181 acaagcttta actggacttc aatttcagct gaaagaacaa ttaggagaaa aggagagaag
      241 acttcaaatc agccaggaaa tcagtgccca tagaacagag ttccacatgc agttttcata
      301 caaaccagtg ttgcatagac ttgtcccagc aagaccacaa atttattcaa gtcaattacc
      361 atcctttacc agggtcccag cacacctgga aagttctgca aggcctcagc tacagaaagc
      421 ccagagacag aaagtaaact ctttcatgac ccttgatcat cagatcatca atccaactct
      481 taaatggtca caacctgcag tgccaagtgg tgggcctctt gtgcagcatg cacacacaac
      541 tctggacagt gatgctggcc tcacagaaaa cccactcacc aagttactag ctattgggaa
      601 agaagatgac aatgcacaat ggcatatgga ggacgttatt gaggatataa tcggtatgga
      661 atcaagtttt aaagaggaag gagcagactc tcctctgcta atgcaaagaa cattatctgg
      721 aagtattttg gatgtgtata gcggtgaaca aggaatttca ccaattaaca tggggcttac
      781 aagtgcttct tgtccaagta gtctaccaat gaaaagagaa attacagaaa ctgacactag
      841 agctttagca aaagagagac aaaaaaagga caaccacaac ctcattgaaa gaagaagaag
      901 gtataatatt aattaccgaa tcaaggagct tggcactctt attccaaagt ctaatgatcc
      961 tgatatgcgc tggaacaaag gaaccattct aaaagcatca gtggagtaca tcaagtggct
     1021 acaaaaagaa caacagagag cccgagaatt ggaacacaga cagaagaaat tagagcaggc
     1081 taacaggcga cttctacttc ggattcagga actagaaatt caggctcgta ctcatggtct
     1141 gccaaccctg gcttcacttg gcacggttga tttaggtgct catgtcacca aacagcagag
     1201 ccatcctgag cagaattcag tagactattg ccaacaactg actgtgtctc aggggccaag
     1261 ccctgagctc tgtgatcaag ctatagcctt ttctgatcct ttgtcatact tcacagattt
     1321 atcatttagt gctgcattga aagaggaaca aagattggat ggcatgctat tggatgacac
     1381 aatctctcca tttggaacag atcctctgct atctgccact tcccctgcag tttccaaaga
     1441 aagcagtagg agaagtagct ttagctcaga tgatggtgat gaattataag aaataaacag
     1501 acccaattca tcaactggaa agcaattcta tgctggtgct atgcaattat gctctgtgtt
     1561 tcatatgttg ctttggctta ttttttttct taaaggaatg tgttgttcat gaaaaactga
     1621 tagaagcaac agaagaattc gcaggaagaa aaatcatagt gttaatgaat tattgagggc
     1681 gaaaaaaagg tgttttcttc tttgactacg gagtccaaat ccacttaaat tctgttttcc
     1741 tgaaaagagg tacagcataa gaaatagctc tttattgatg ttttaaaagc agcaacttgg
     1801 tggtgtacta ctggaactaa tgactgcaaa gtgttaaacg actgaaatat acaaacagtc
     1861 tcttagttac tcatttccat cttctcttca actttcacat cagtcttccg gaatcaagat
     1921 caacatatca ggtggtcatt gcctttctcc attgtctagt agacatgtct aaagttcaaa
     1981 ctttatagga taaataaatg tataatagat tatctgtcac ttgtggttga aaggcaaatc
     2041 tacaataaat gtgagaattt tccacaataa aatatggata acttataaaa acattggtta
     2101 ctaaaattag atcctcattt tattgtagtt ggttcaatta cactaattct aaaagcatcc
     2161 atgcatattt atatctccag tctctgttca ggaaaaggaa catattgaat attttcctca
     2221 ggaatatgga ccagaattgt atcccttcac acaaacatac acatacacat atgcacatca
     2281 ttcaggtagt atatgttctt ttgttttctt catgcttctg actgcatcag aatcacattc
     2341 caaattctct tttcttatga agaagagatg tcagatcatc aattttagta aataaaatat
     2401 aaaatgtccc cctgcaagga cagttttcag gtacttaaaa cttttcatca gtattggaca
     2461 gaaatcaatt agttgttgat ttggtttttc tccaaatgga taaaatattg aaaattgaat
     2521 tgccaattga caaaataatt attacaacaa actatttctt attattttca gttctgagag
     2581 gaacgtaagg ttctatttct ataaacactt agagtgtcct atgatctttg gttgcactgt
     2641 tagcatttat tataagcact tataactatg atgcttcatt tagattttta tctcttgcgc
     2701 ttgttttagg ttaggaaatt aagttaccaa gcacgttgct ctgtgctgga cctccaagag
     2761 tgatcatccg atcaatgagt attcatggag gcatactcag aactgcagtg agtcctgaga
     2821 aaatgtagaa gagttgaaaa agatatggtc ttactcctaa ggtagttaat gagaatgcat
     2881 gaaaaacaaa aacaaaagat agaagacata tagaataaaa aatctaagca taaactgtaa
     2941 atacagaagg tcagagaaaa tgaaaatgac tgacaaactt tatgggaaca gcagaatttg
     3001 acttctcttt gaaaggcatt aattgagtga aagtgagggc atataaagga ataataccaa
     3061 ccaaatgata aaagtgagaa taatagggga agtatcttta taggacttta attagaaaga
     3121 tctggatgcc ctagaagatg tctgttgggg agttctgaag cataagactg acaacaggtt
     3181 gtgaaggccc ttagaaaact atggtgaaat aatatagtat taatataata gaaacaaatc
     3241 tttttagtag cagggaggat gctaaaaact aaaatatata ttactaatga gtgagatgta
     3301 atctttcatg aatattaagc tttgggataa attttgaaag gatcttttag ttgcttctca
     3361 catggaaaat atgtcactat gaaatgtgag accctaatgc tgataaaagt agaaaaatag
     3421 taaatcatta tggtataata attatctcag gcttagcttg tatcatttgc tcagaatttg
     3481 gagaattaaa ataattttat tgtttgacat ggaaaaataa ttactaactt ctgggtacag
     3541 tcattaaagc ctgatagata aattcatctg aaatatgcca tgtgaaacag ctattagata
     3601 catcttctca ataattttca agacgatatt acatactttt aattttataa caaaattcca
     3661 cttcattatc tgagttgata atttgattaa atgttaaaaa ttatagataa ggaatatatt
     3721 ttggagttca tagaaaacac accactttat tagatagaga ctggcttcag ttctcatttt
     3781 atctgctctt ctcatttctt catattttga gtagacttgc actgatgatg tcattactca
     3841 gtcattattt tctgttctgt taaggtacaa ctactgggcc ttgaaatcta tccttcacaa
     3901 tcttggctga gataaggact tggcacagga tgatagagcc tggacacaag agatctggag
     3961 agggaactgc tatttgctgc tacattcaga ttatgagatg tcagggaact gtaaaaaggg
     4021 taatgaattt ttaaagagag taaagagtta tgctgtgtcc cggtcaactg aaatacatta
     4081 aaaattaatt agatggtagt tcttaacttt ttaaggcaga taccttgaga atctagtgag
     4141 ttatagaccc tctccctaga aaagtataga actgtttata tggacaataa ttcacatgca
     4201 ttcagagatc ttagggatct cctgaatgtt ttcttggatc ccaagtgaaa aattcctgaa
     4261 tcaggtctct taggtgtgcg gttaatgtca tgtataacaa tggggggacc cttacttatc
     4321 taaatataat tatcccaatc ctaataatga tgaggttgca taggaaagta atagtgtacc
     4381 aaactttaga ttattcacta aaaaagttgt tcatttatga agtagtcgtt tatcaaacat
     4441 gtcctcccca ctcagcaaac tatgccttct atttattata tatgggtcag tttcactata
     4501 attactgagt gttataaaca tctgaccata acattttgaa atgatgcaaa taaatttcca
     4561 aacaaaaata gtgtgaattt aaaagcaaat tatttgagta tctaagaaac aagatagact
     4621 tctagaaaaa tttgactctc tagaatattt cttgcagaaa tgagattttt cataatagta
     4681 aaagaggcat atgtttatca aacaatgctg tcacaaaaag catcaactgt aatgggacta
     4741 ttaatgcata attattgatt tattcattca attaatatac aattatccct tttcatttaa
     4801 agatttaatt cataattaca attataataa aacttccttt aaagtaagat acaataattt
     4861 tattgttttt cattcttttt tcaacaaaat atcccatcca atcatttttt atattattaa
     4921 atattggctg ctttttcttg gattcacatt aaacagccct ttccaacttc caattgtctt
     4981 aaaataatga tgacctcctg tgagtagata cagctcttta caattttttt ctttagtgcc
     5041 ttttcttctt gaatttttcc tatatcaaat ggagaatata tgtacagatg gtattttctc
     5101 agtttatagg catatcagtg accatggctt tctttatata ggtttttaaa aaagccctaa
     5161 ataataaata gccagatgag ctggggacat tgagaaatag ccttcctctt cctttttcaa
     5221 ctcatttttt tcccacctac atgactgtaa atcaaatatt taatagctct tacttaaaaa
     5281 aacagataca aagaatgtct tgatttggtg tgctcattta ccataatgtc atgaggggaa
     5341 ttagatttca caactttaaa aggaatatat ttttatttta ttttgaaaaa ctgagtcata
     5401 taggaatttt cttatacttc aaggcatcat ggaaacactt ttttcctgtt tggatattgt
     5461 ggaatttaaa cgttcaaata aataaatggc ataactaagt gttccaaatt tttttacaat
     5521 gtctttgacc ctattcaaac actttaggta tttactgacc gtctgatgtg taagatgtgg
     5581 aataaaactg gaatcaatta attatttcac tgtgttatca gcgcaagatc aaccatctgg
     5641 gtttcttaaa gacacccgaa ggattgaatt ttgtttcagt attgataatg gcatagtctc
     5701 tatgtgctac atggaattac atcatttatc cctccagtgc cctatatgtt gataagtatg
     5761 tcagtttgac ttagtataca tatatacaga gatttcatta catttaccta ataaatacaa
     5821 aatacatttc gagtgttact gatctcctat gttacatgag cctcctgtaa tcattgtgca
     5881 ttgatgttcc aatgttttat tgtttgtatg aattttaatt tgaaaacaag gaaacaatcc
     5941 aaaagcagaa aaaatagctt ttcttaaaat tttcagtgct acattttccc tctgaggtcc
     6001 atagagattt gaatgtatag gagattatcc gaaaacagct attttgatta aaaaatatat
     6061 ctcccaggat tcaaccaact taatgatgaa gtactattgt ctactgcttt atacataaaa
     6121 gggaactttt tatctgcttg taaagggatt tttatgtgta tttctgcata atcagatgac
     6181 ttctattgtg ttttctactg atgaaattct ctgtaaaatg tctttttctt acattatcca
     6241 acaggcataa agaataacag taaagacttt tgtgtttgta atactacctc ttttatccct
     6301 gcactactgt tttattgcaa aaattctata ttgtcactgt attttttcca tagaatataa
     6361 attttgttct tgtgctaaag ctggtagttt atgtagcaga caaaatatac aaataaaaga
     6421 agagactgat tttgctgaaa gaattatata taatcaagaa gttacatatt gttctttaaa
     6481 tatgatactg aattttaaaa gcaaacgaaa ttcaagaatc ttatctaaca gcatagcagt
     6541 tgcttatggc atacaaggct aaaattaatt cagctattta atcttaataa ttattatgta
     6601 gttaaaaatc tttgacttta atagtgtttt acatatacaa atagctgaag taacattcct
     6661 ataattttaa tctgacattg gttagatcaa gaaaacattg ttaataagac tgtagaattt
     6721 gtaattattg ctatttttca tttttaataa caaagtaatg tgtcttattt tctaagaaaa
     6781 tggagaactt tggtgtactt taatacatac aaaaatcttt gtaaaaatac cttaaaatgt
     6841 accaatattt tctttgcata tattaaatga aagactataa ttatgaaa
//
