LOCUS       NM_006286               9395 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens transcription factor Dp-2 (TFDP2), transcript variant
            2, mRNA.
ACCESSION   NM_006286
VERSION     NM_006286.5
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9395)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 9395)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 9395)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 9395)
  AUTHORS   Hauri,S., Comoglio,F., Seimiya,M., Gerstung,M., Glatter,T.,
            Hansen,K., Aebersold,R., Paro,R., Gstaiger,M. and Beisel,C.
  TITLE     A High-Density Map for Navigating the Human Polycomb Complexome
  JOURNAL   Cell Rep 17 (2), 583-595 (2016)
   PUBMED   27705803
REFERENCE   5  (bases 1 to 9395)
  AUTHORS   Yang,X., Coulombe-Huntington,J., Kang,S., Sheynkman,G.M., Hao,T.,
            Richardson,A., Sun,S., Yang,F., Shen,Y.A., Murray,R.R., Spirohn,K.,
            Begg,B.E., Duran-Frigola,M., MacWilliams,A., Pevzner,S.J.,
            Zhong,Q., Wanamaker,S.A., Tam,S., Ghamsari,L., Sahni,N., Yi,S.,
            Rodriguez,M.D., Balcha,D., Tan,G., Costanzo,M., Andrews,B.,
            Boone,C., Zhou,X.J., Salehi-Ashtiani,K., Charloteaux,B., Chen,A.A.,
            Calderwood,M.A., Aloy,P., Roth,F.P., Hill,D.E., Iakoucheva,L.M.,
            Xia,Y. and Vidal,M.
  TITLE     Widespread Expansion of Protein Interaction Capabilities by
            Alternative Splicing
  JOURNAL   Cell 164 (4), 805-817 (2016)
   PUBMED   26871637
REFERENCE   6  (bases 1 to 9395)
  AUTHORS   Zhang,Y., Venkatraj,V.S., Fischer,S.G., Warburton,D. and
            Chellappan,S.P.
  TITLE     Genomic cloning and chromosomal assignment of the E2F dimerization
            partner TFDP gene family
  JOURNAL   Genomics 39 (1), 95-98 (1997)
   PUBMED   9027491
REFERENCE   7  (bases 1 to 9395)
  AUTHORS   Loiseau,L., Pasteau,S. and Brun,G.
  TITLE     Molecular cloning and expression pattern of the DP members of the
            chicken E2F transcription factor
  JOURNAL   Gene Expr 6 (5), 259-273 (1997)
   PUBMED   9368098
REFERENCE   8  (bases 1 to 9395)
  AUTHORS   Rogers,K.T., Higgins,P.D., Milla,M.M., Phillips,R.S. and
            Horowitz,J.M.
  TITLE     DP-2, a heterodimeric partner of E2F: identification and
            characterization of DP-2 proteins expressed in vivo
  JOURNAL   Proc Natl Acad Sci U S A 93 (15), 7594-7599 (1996)
   PUBMED   8755520
  REMARK    GeneRIF: This study demonstrates translation from an internal
            methionine.
REFERENCE   9  (bases 1 to 9395)
  AUTHORS   Zhang,Y. and Chellappan,S.P.
  TITLE     Cloning and characterization of human DP2, a novel dimerization
            partner of E2F
  JOURNAL   Oncogene 10 (11), 2085-2093 (1995)
   PUBMED   7784053
REFERENCE   10 (bases 1 to 9395)
  AUTHORS   Wu,C.L., Zukerberg,L.R., Ngwu,C., Harlow,E. and Lees,J.A.
  TITLE     In vivo association of E2F and DP family proteins
  JOURNAL   Mol Cell Biol 15 (5), 2536-2546 (1995)
   PUBMED   7739537
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC319314.1, U18422.1,
            AC112504.6 and BC040991.2.
            
            On Jun 2, 2019 this sequence version replaced NM_006286.4.
            
            Summary: The gene is a member of the transcription factor DP
            family. The encoded protein forms heterodimers with the E2F
            transcription factors resulting in transcriptional activation of
            cell cycle regulated genes. Alternative splicing results in
            multiple transcript variants. [provided by RefSeq, May 2010].
            
            Transcript Variant:).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11853559.23831.1,
                                           SRR14038196.2659698.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                DC319314.1         40-57
            19-1536             U18422.1           10-1527
            1537-8982           AC112504.6         9263-16708
            8983-9395           BC040991.2         1878-2290
FEATURES             Location/Qualifiers
     source          1..9395
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q23"
     gene            1..9395
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /note="transcription factor Dp-2"
                     /db_xref="GeneID:7029"
                     /db_xref="HGNC:HGNC:11751"
                     /db_xref="MIM:602160"
     exon            1..48
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            49..152
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..1310
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /note="isoform 1 is encoded by transcript variant 2;
                     transcription factor Dp-2 (E2F dimerization partner 2)"
                     /codon_start=1
                     /product="transcription factor Dp-2 isoform 1"
                     /protein_id="NP_006277.1"
                     /db_xref="CCDS:CCDS43159.1"
                     /db_xref="GeneID:7029"
                     /db_xref="HGNC:HGNC:11751"
                     /db_xref="MIM:602160"
                     /translation="MIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDR
                     KRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFT
                     NSNNHLAADSQAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNL
                     EIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFII
                     INTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKL
                     AKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLD
                     AEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE"
     exon            153..274
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            275..322
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            323..485
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            486..632
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            633..701
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            702..853
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1020
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1126
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..9395
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1306..1311
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /note="hexamer: AATAAA"
     polyA_site      1335
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /note="major polyA site"
     regulatory      9355..9360
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /note="hexamer: AATGAA"
     regulatory      9377..9382
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /note="hexamer: AATAAA"
     polyA_site      9378
                     /gene="TFDP2"
                     /gene_synonym="DP2"
     polyA_site      9395
                     /gene="TFDP2"
                     /gene_synonym="DP2"
                     /note="major polyA site"
ORIGIN      
        1 gtagaatgtt gttggtactg cagtgagagg catgcttcct tagaccaggc aacatttcat
       61 ttgttgcatt tccagtttcc aataccaact cacctacaaa gattttacca aaaaccttag
      121 gaccaataaa tgtgaatgtt ggaccccaaa tgattataag cacaccacag agactaacca
      181 gttcaggaag tgttctgatt gggagtccat atacccctgc accagcaatg gttactcaga
      241 cacacatagc agaagctact ggctgggtcc ctggtgatag aaaacgggct agaaaattta
      301 tagactctga tttttcagaa agtaaacgaa gcaaaaaagg agataaaaat gggaaaggct
      361 tgagacactt ttcaatgaaa gtgtgtgaga aagttcaacg aaaaggtaca acatcgtaca
      421 atgaagtcgc tgatgagctg gtgtcagagt tcaccaattc aaataaccat ttggctgctg
      481 attcgcaggc ttatgatcag aagaacatta ggcgaagagt ttatgatgct ttaaatgtgc
      541 taatggcaat gaacataatt tcaaaggaaa aaaaagaaat caagtggatt ggcctgccta
      601 ccaattctgc tcaggaatgt cagaatctgg agatagagaa gcagaggcgg atagaacgga
      661 taaagcagaa gcgggcccag ctgcaagaac ttctcctaca gcaaatcgct ttcaaaaacc
      721 tggtacagag aaatcgacaa aatgagcagc aaaaccaggg cccgccggct ctgaactcta
      781 ccattcagct gccattcata atcatcaata caagcagaaa aacagtcata gattgcagca
      841 tctccagtga caagtttgag tatcttttca attttgacaa cacctttgag atccatgatg
      901 acatagaagt actaaagcgg atgggaatgt cgtttggcct ggagtcaggc aaatgctctc
      961 tggaggatct gaaacttgcg aaatccctgg tgccaaaggc tttagaaggt tatatcacag
     1021 atatctccac aggaccttct tggttaaatc agggactact tctgaactct acccaatcag
     1081 tttcaaattt agacctgacc actggtgcca ccttacccca gtcaagtgta aaccaagggt
     1141 tatgcttgga tgcagaagtg gccttagcaa ctgggcagtt cctggcccca aacagtcacc
     1201 agtccagcag tgcggcctct cactgctccg agtcccgagg cgagaccccc tgttcgttca
     1261 atgatgaaga tgaggaagat gatgaggagg attcctcctc cccagaataa agacaagaga
     1321 aagcctacgt ttcaatatgt gatgctcatg tgtgtttgta gtgtgagctc ttgtttttga
     1381 aatgattgct tcagtctttg cctttgtttg cactgtgtgt tcagtgaaaa ctagagaaac
     1441 acaataagca aatcacatga aggctgagat gattgagatg aaagttaaca tagtgtgaat
     1501 gaaagtctgg ccaacagagc agtagatgat ataacaaaga aagcatgctt tctgaggaga
     1561 tagtggggat aatccctgaa gagttggcag tgtgagtgca actcatttat cttctgtgag
     1621 gtgggatttt tgtgttcctc acacccatgt aattattctt agaattgaga ttgctacacg
     1681 gagcagtcct tgacgatcgt gtttctgacg tttctcttcc ttgcctggac tgcctttgac
     1741 aaggcagaaa tgaacatgaa aagtccccag gagaggggag ctgtgtagtg agggatactg
     1801 agggcagtcc tgtggctgag gggcacagat tgaactgctg aactagttgg aggtctagat
     1861 gaggtgcttt acgcatcagc tgccttagac agcttctaga aaggagcgag cgctacttct
     1921 taagtactta agtgacattt agataattta tagtaaaact gaaattatta ttagccaatg
     1981 cattggtgca tagaatttac tagggctact tctggaagcc aaaatagaat agcatttcca
     2041 tgtgcattaa atactttgcc agcactgcct ttgccagcat cctaaatctg gagttttaca
     2101 aagaaggaaa ctgtatcttt aggttaatca aagctatgca tttcatatag ctttttcatt
     2161 taaaacaaga caaagaaaca aattcctatg accaaattgc ttgcctacag ttccctgcag
     2221 taattgtatg atctcaccca gtgtgcaatt tgtgaaaatg aaccaaatgt cattactttt
     2281 gtcttaaaga aaagtctatt tcaagaatat gaacagcagt gtttccttgt acatgtcacc
     2341 ttttttcaca ttttcattaa tcagaatgac cttattgagc ctactcctgg ggtcaattgc
     2401 atttcaaact aatccaatat ttagtgtttc acagaaacac tagaaaacgt tgaacactcc
     2461 tactgcctgg atatatggta gtgcagttat gttgtttatg gctcaagatg tcattagaaa
     2521 tactgcagtg gtgtattcac agctgctcct tctctgaatg aaagagtgta gggacacctg
     2581 ccaccatggc cagaccctga ctgaatttca cattaaggct ttggaaagga gcaaataata
     2641 atgggagaat taactccaaa actttgacct gaatcatgtg gatttgtccc aagattatgc
     2701 tagatgcacc aagcatggcc caaattggtt cttttttaaa tcccatgggg gaagtgcagg
     2761 ctccttcctg tggtgcctct ttatagcctc accaccatgc taacactgag catggtgagg
     2821 aggaggaagc tttggctagc taaacatgtt taataaggcc ataaaaactg agaaagaaaa
     2881 acattcaact ttagctgaag ctcctttgat acaaaagttt cattctgtca gaaataagcc
     2941 atagtacaga ctcagagata gaggcagttt ctagagaact cggtcttatc gtgggttctg
     3001 gagcacacct ctcagaccag tcaggaacac tggggaggtg acagcaggtc cccaggggcc
     3061 tgcagggaat ctttcagctg cacggattgg gatttccctc caaaccaaac tgtcctttaa
     3121 ggggcagcct cctcttttac taactccacc ctttctcatc tctgggaccc agcagggacc
     3181 tggagaggcc aacagccact gctacctttg tagtcttcaa aatattgaac tgcaggtccc
     3241 aagatgcatt tcaggattta agacaggtgc actaatgata accattcctt caccaagtag
     3301 caacattctt gccagagttc ttgggaaacc tgtttttttc tctactctcc atctctgctg
     3361 ctctcatgct ttaaattgat aaaatatggg ctcaaaaaaa gaaagccgcc aaagactctt
     3421 atccttattg gtgccccatc attggccacc ccagccatag gtgtgtgctg ttggtgggaa
     3481 atggtctcct tcctcagcgt tgtgtttggg ttactggtga ggccagctca cagagtgaca
     3541 tcatggtcac cagtacatgt cgctggagta aaatcttgcc tttagaaact aggttgagct
     3601 gttcagaaag gtcaattctc ttctgtattc cccctcaaca tttatctggg tctaaagctc
     3661 agcactgagt cacaatttca cacaagatca aagtgaggca gtgttaggaa accatgggct
     3721 gggtgcagtg cctctcgcct gtaatcgtag cactttggga ggccgaggcg ggcacattgc
     3781 ttgagctcag gagttcaaga ccagcctggg caacatgaca aaaccctgtc tctacaaaaa
     3841 tacaaaaatt agctgggtgt ggtggggcat gcctgtagtc ctggctactc aagaggctga
     3901 ggtgggagga ttgcttgagc gcaggaggcg gaggttgtag agccaagatc acaccactgc
     3961 actccagcct gggtgacaga gcaagaccct gtctcaaaaa aaaaaaaaaa aaaaatggaa
     4021 gttgtggtca caatgcccag gcttctttgt tatagtggca cgctgggtta cttgccacac
     4081 acagatcact cctcccaggg ctgctggcac acactgattg tggggagttc aagaggcctt
     4141 ttccccttga gggtgtggct gtcccccttt caggcgtgtg gcgtcattca tggaggaagt
     4201 gctggctcta cttagcacac gcacagtggc actaggacct gcgtgcctgg ccctcagtgg
     4261 gtagggcggt gctgcctagg cacacagcag cgcttacggg ccccaggtgc ctactaggct
     4321 gccttcctct tccccgctgt cagtctgtgt cctccacgtg cttatttcct gtggtgagag
     4381 cagttgtggt gtttgtatac cttgtgcctt atgatcaagg tgggccttgg aggagggcgg
     4441 gaaaggagcg accaacatgg cggtcctcca cccctcagcg acacccaccg cccgagaaac
     4501 tacagacaat ggccacaagt ttggcgtcct tcaatttaat tctttaaaga agtgctggga
     4561 agaaaaagct atgtggtttc taccatttta gcaggataaa gaggataact ccttccatta
     4621 gcaaatttta cagttgttaa cagtactctg ccatatttga aaaataatgc cagagtcagt
     4681 ccttgaaaac aaggtagctc ctatcagaat tcaaatggaa attttttttt tttttttttt
     4741 tttttttgag actgagtctc gctctgttgc ccaggctgga gtgcagtggt gatctcggct
     4801 cactgcaagc tccgcctccc gggttcacgc cattctcctg cctcagctgg gaccatgcct
     4861 ggctaatttt ttttgtattt ttagtagaga cggggtttca ccgtgttagc caggatggtc
     4921 tcgatctcct gaccttatga tccacccctc tcggcctccc aaagtgctgg gattacaggc
     4981 gtgagccacc gcacccggcc tcaaatggaa atatttcaca gaggagtggt tcagtttagc
     5041 cctgcaagac atctataact tgactgtttg ctaaaccaca actctttttg gctacttggg
     5101 tcatagagac agcagagttg ctccaagtat aaatgtgact taggctccct ccagcacaca
     5161 gtgtgtatgt tggagggagt gtggattagc agagaatgag aactacctca gctattcctg
     5221 ccataaccac actgagagag gggggcacgg tggggagcct atttagcttt tttttttttt
     5281 tgagacggag tcttgctctg tcgccaggct ggagtgtagt ggcgcaatcc cggctcactg
     5341 caacctctgc ctcccgggtt caagcgattc tcctgcctca gcctcccaag tagctgggat
     5401 tataggcgca tgccgccaca cccgactaat tttttgtatt tttagtagag tcagggtttc
     5461 accgtgttgc ccaggctggt gtcgaactcc tgacctcagg tgatctgccc acctcagcct
     5521 cccgaagtgc tgggattaca ggtgtgagcc accgcacccg gctctattta gctttttaaa
     5581 aattatttcc tttcaagggc cctttaatat ctatcaagct ccctccccta acaaaatggg
     5641 ctgtccctgc ccaacaagtc tgaaatagac cttaaaactg tgctgcctta gtggtaagta
     5701 aggggtgggg gttggacagt gaatcttaag atttcatcct tcattcagta agcatttgag
     5761 tacctactgt gagcaggcat tggggcggag cagcgagagc cctgccgatg ttgggttctc
     5821 ctcctattgg ggaaacttga tcacagatgg aacacgtgca gattgattga tgagtgctgt
     5881 ggagaaagca gcagcgtagc gggaccgttt gggaaaggct actttggctg ggggtggctg
     5941 ggaaaggccc ctctgggaaa gagacagttt tactgagtca gatggtggaa agacagatgt
     6001 ctctatactt tcttaacaag ccactctgtc ccataacatg cacttggaat ctctcctaag
     6061 ttccagaggc cccactgttc cagtttcaag ccttcatttt ggagtctgtt tgggaacttt
     6121 taagacttca aagcaaagtt agctaccagc aatttctgta aaccaagaga agattgtcac
     6181 aaagattcac tactttccaa ctgaatctat gcagtagaaa aatcattaga aaatacaaaa
     6241 attagccggg cgtggtggca catgcctgta gtcccagcta ctcgggaggc tgaggcagga
     6301 gaatcacttg aacccaggag gcggaggttg cagtgagcca agatcccgcc actgcactcc
     6361 agcccaggtg acagagcagg actctgtctc aaaaaaagaa aaaagaaaga aagaaaaatg
     6421 attagaaatt gagaactatt ttacgtgttt ctaagttgtt ggctacatca aagagatcat
     6481 ctgtattctg catatgggct ggctttggtg aagctgatga ctggacttct aagaaccgtt
     6541 ttcccaaatg ggttcccata ttcatgcacc caaagcaatg gtccccaagc actgatgaaa
     6601 actaatatgc atttcccaaa gacccacact atgtatcagg agcctgcacc atgccatttg
     6661 aatgaccctc agcaatgtgc ctccctgccc tcaaattccc agttgataac agtgtttgat
     6721 taaatttcca ctcaagccaa acatggttac taagaagaga aaaacctgat gtttgcataa
     6781 tatttttttt cccctcgaga tggagtcttg ctctgttgcc caggctggag tgcagtggca
     6841 tgatctcagc cactgcaacc tctgcctccc gggttcaagc gattcttctg cctcagcctc
     6901 ccaagtagtt gggattacag acatgtgcca ccacgcctgg ctaatttttg tatttttagt
     6961 agagacaggg tttcaccatg ttgaccacac tggtcttgaa cttctaacca tgtgatctgc
     7021 ctgcctcggc ctcccaaagt gctgggatta caggcttgag ccaccacgcc cagcctaaga
     7081 ttttatgatt aaaaaaaatt caagctcaat acccacataa attataacgt ttctcaggaa
     7141 gtagtccctt aaccaaaacg tctctgagaa gtgatgctta ggtaatctct gggatccgat
     7201 tttcccacat gtctcactcc acagtatgct aaagaagaaa aagtgagtgg gcacaacact
     7261 ttgaccctct ggctaagccc tgggagtccc tgacaggtcc agaaacttct ctgacaccca
     7321 ttcaccaggg tgctgagata ggagaaagtg ctcatttata atgtgtattc tgtgcagctg
     7381 ttctcagaca agaccggatc ttgtcatctt accttttgct ttacaaaaaa ggcctgttga
     7441 agtcaatgct gtcttgcccc ttgctgtttc agcaggttag actttggtct tcactgctta
     7501 tagctgcatt ggaggccaac gtagctgatg ctcagggtca ggcctcgccc cttcgccgca
     7561 ggtctcagga tcggggataa catcgctccc accctgctca tttagagatg ggaaacaagc
     7621 aagagcttga cttgcctccc atccctcagc ctgtctgtgg cagagcctgc accaaaaccc
     7681 agagcttctt ccctccgtga gggccacgct gtcaccacag tcctcccaga tgggttttgg
     7741 attagcatca gtcctgtgtc accaagtgcc aaacagctga ggggtagaag tgggactcct
     7801 ttcccgagcc ccagcatgag gctgtggtgt caggtttagg cctctctcaa gtcagaaaac
     7861 cccgggctga gacctccaca gacaagggct ccccatgctg gccattggca ggggcccaag
     7921 aagttcagtg accaactggt ccttccacac cacaccagct ggtgctgccc atgtctgtcg
     7981 aatcataacg gaaaattccc cagatcacgt ttggatttaa aaactcatcc cttgtcgtgc
     8041 ttcaatgcat gccatttgtc acttaccata cttcaccatg gccgagcttc atgtcacatg
     8101 gcctggcgat tgtgcttgtt cacactgggg ccaggatttt catactaaaa cgtcactgac
     8161 aatggggcta cttttctcct gaatagctcc tctgggcttg ttgcagttct agttttccca
     8221 gtagttccat ggcaggttca acctctcagt gtcctgaaaa atggaaccac ccactaacca
     8281 tatgcactgg ctgcccaggt ggctgcactc cggggatcac gtttcagtac tgagttcctt
     8341 cacgcacttg gttcaccacc atcactcttg agttttggac aaaagaggtg ggtatgccag
     8401 gcacagtggc tcacgcctgt gatcccagca ctttgggagg ccgaggcggg cggatcacct
     8461 gaggtcggga gttcgaaacc agcctgacca acatggagaa accctgtctc tactaaaaat
     8521 ataaaattag ccgggtgtgg tggcgcatgc ctgtaatccc agctactcgg gaggctgagg
     8581 caggagaatc tcttgaaccc aggaggcaaa agttgcaatg agctgagatc gtgccatttg
     8641 cactccagcc tgggcaacaa gagcgaaatt ccatctcaaa aaaaaaaggt gggtaaaggg
     8701 ccatgagccc aaaccactag gttgttcacc ttttcatctg aaaatgcttt actctgacta
     8761 tgtgctattg ggttttattt ccagaaaata tagttctcct tttttctgca tgaaggatac
     8821 atcgtggtgc cacatgcttt aagcaattta aacaagagag ataagaggaa aatgcaacca
     8881 ccacatctga cttgcccaat gtagactttc ctttattaga ttgaagtaca caacctaata
     8941 tgatatatta ttttgtagta tctcagactt tgtaaataaa tgccattatt tttatatgga
     9001 aattttatag aagagctatt tctgtatacg taattactcc tgattttctg aaattgcttc
     9061 tggtagataa cagacaagtc ctaagcagtg ttccactaag ggtggttcca ggcctgcctg
     9121 ccgtggagtt gactggggga attttacagt tttgcgatcc taggatgcgt cccagacgct
     9181 cagtcagaag tgctggaggt ggggcctggg aagctgtatt tgtaatgaac tctggtgttt
     9241 tttgtccatt aaagtgtatc tttgtccatc ctataagatt aaaggaaaga aaaagcatct
     9301 caaatgagtg taagttgttc ttgagaaaaa aatgtatcag acttttatga tttgaatgaa
     9361 atgtattata gaaaaaaata aacactttaa aataa
//
