LOCUS       NM_014553               9287 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens transcription factor CP2 like 1 (TFCP2L1), mRNA.
ACCESSION   NM_014553
VERSION     NM_014553.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9287)
  AUTHORS   Vokshi,B.H., Davidson,G., Tawanaie Pour Sedehi,N., Helleux,A.,
            Rippinger,M., Haller,A.R., Gantzer,J., Thouvenin,J., Baltzinger,P.,
            Bouarich,R., Manriquez,V., Zaidi,S., Rao,P., Msaouel,P., Su,X.,
            Lang,H., Tricard,T., Lindner,V., Surdez,D., Kurtz,J.E.,
            Bourdeaut,F., Tannir,N.M., Davidson,I. and Malouf,G.G.
  TITLE     SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting
            renal medullary carcinoma transformation and ferroptosis resistance
  JOURNAL   Nat Commun 14 (1), 3034 (2023)
   PUBMED   37236926
  REMARK    GeneRIF: SMARCB1 regulates a TFCP2L1-MYC transcriptional switch
            promoting renal medullary carcinoma transformation and ferroptosis
            resistance.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9287)
  AUTHORS   Sohn,E.J. and Nam,Y.K.
  TITLE     The Transcription Factor TFCP2L1 is Associated with Myelination via
            miR708-5p Regulation in the Peripheral Nerve System
  JOURNAL   Neurochem Res 47 (2), 434-445 (2022)
   PUBMED   34581937
  REMARK    GeneRIF: The Transcription Factor TFCP2L1 is Associated with
            Myelination via miR708-5p Regulation in the Peripheral Nerve
            System.
REFERENCE   3  (bases 1 to 9287)
  AUTHORS   Zhang,M., Ji,J., Wang,X., Zhang,X., Zhang,Y., Li,Y., Wang,X.,
            Li,X., Ban,Q. and Ye,S.D.
  TITLE     The transcription factor Tfcp2l1 promotes primordial germ cell-like
            cell specification of pluripotent stem cells
  JOURNAL   J Biol Chem 297 (4), 101217 (2021)
   PUBMED   34555410
  REMARK    GeneRIF: The transcription factor Tfcp2l1 promotes primordial germ
            cell-like cell specification of pluripotent stem cells.
REFERENCE   4  (bases 1 to 9287)
  AUTHORS   Hancock,G.V., Liu,W., Peretz,L., Chen,D., Gell,J.J., Collier,A.J.,
            Zamudio,J.R., Plath,K. and Clark,A.T.
  TITLE     Divergent roles for KLF4 and TFCP2L1 in naive ground state
            pluripotency and human primordial germ cell development
  JOURNAL   Stem Cell Res 55, 102493 (2021)
   PUBMED   34399163
  REMARK    GeneRIF: Divergent roles for KLF4 and TFCP2L1 in naive ground state
            pluripotency and human primordial germ cell development.
REFERENCE   5  (bases 1 to 9287)
  AUTHORS   Taei,A., Kiani,T., Taghizadeh,Z., Moradi,S., Samadian,A.,
            Mollamohammadi,S., Sharifi-Zarchi,A., Guenther,S., Akhlaghpour,A.,
            Asgari Abibeiglou,B., Najar-Asl,M., Karamzadeh,R., Khalooghi,K.,
            Braun,T., Hassani,S.N. and Baharvand,H.
  TITLE     Temporal activation of LRH-1 and RAR-gamma in human pluripotent
            stem cells induces a functional naive-like state
  JOURNAL   EMBO Rep 21 (10), e47533 (2020)
   PUBMED   33252195
REFERENCE   6  (bases 1 to 9287)
  AUTHORS   Henderson,Y.C., Frederick,M.J., Wang,M.T., Hollier,L.M. and
            Clayman,G.L.
  TITLE     LBP-1b, LBP-9, and LBP-32/MGR detected in syncytiotrophoblasts from
            first-trimester human placental tissue and their transcriptional
            regulation
  JOURNAL   DNA Cell Biol 27 (2), 71-79 (2008)
   PUBMED   18004979
  REMARK    GeneRIF: LBP-1b and LBP-9 both stimulate LBP-32/MGR promoter
            activity.
REFERENCE   7  (bases 1 to 9287)
  AUTHORS   Huang,N. and Miller,W.L.
  TITLE     LBP proteins modulate SF1-independent expression of P450scc in
            human placental JEG-3 cells
  JOURNAL   Mol Endocrinol 19 (2), 409-420 (2005)
   PUBMED   15471945
  REMARK    GeneRIF: LBP-1b is an important SF1-independent transcriptional
            activator stimulating P450scc expression in human placental JEG-3
            cells, whereas LBP-9 modulates the action of LBP-1b, exerting both
            positive and negative effects
REFERENCE   8  (bases 1 to 9287)
  AUTHORS   Rodda,S., Sharma,S., Scherer,M., Chapman,G. and Rathjen,P.
  TITLE     CRTR-1, a developmentally regulated transcriptional repressor
            related to the CP2 family of transcription factors
  JOURNAL   J Biol Chem 276 (5), 3324-3332 (2001)
   PUBMED   11073954
REFERENCE   9  (bases 1 to 9287)
  AUTHORS   Huang,N. and Miller,W.L.
  TITLE     Cloning of factors related to HIV-inducible LBP proteins that
            regulate steroidogenic factor-1-independent human placental
            transcription of the cholesterol side-chain cleavage enzyme,
            P450scc
  JOURNAL   J Biol Chem 275 (4), 2852-2858 (2000)
   PUBMED   10644752
REFERENCE   10 (bases 1 to 9287)
  AUTHORS   Mukhamadieva,G.A.
  TITLE     [Functional state of the stomach in patients with diffuse toxic
            goiter and hypothyroidism]
  JOURNAL   Vrach Delo (6), 22-25 (1975)
   PUBMED   1173954
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC013399.6, BC064698.1, AC079988.6 and BM055156.1.
            
            On Nov 22, 2018 this sequence version replaced NM_014553.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC064698.1, SRR18074967.2576154.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000263707.6/ ENSP00000263707.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                AC013399.6         55112-55131         c
            21-3469             BC064698.1         21-3469
            3470-8866           AC079988.6         87890-93286         c
            8867-9287           BM055156.1         1-421
FEATURES             Location/Qualifiers
     source          1..9287
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q14.2"
     gene            1..9287
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /note="transcription factor CP2 like 1"
                     /db_xref="GeneID:29842"
                     /db_xref="HGNC:HGNC:17925"
                     /db_xref="MIM:609785"
     exon            1..155
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..1533
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /note="CRTR-1; transcription factor LBP-9; CP2-related
                     transcriptional repressor 1"
                     /codon_start=1
                     /product="transcription factor CP2-like protein 1"
                     /protein_id="NP_055368.1"
                     /db_xref="CCDS:CCDS2134.1"
                     /db_xref="GeneID:29842"
                     /db_xref="HGNC:HGNC:17925"
                     /db_xref="MIM:609785"
                     /translation="MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARL
                     PPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRV
                     VFHDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPA
                     KRASAFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVF
                     KPKGADRKQKTDREKMEKRTAQEKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYN
                     GSPNSFGLGEGNASPTHPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFS
                     GADLLKMSRDDLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQELEQNRVPLQQKRDG
                     SGDSNLSVYHAIFLEELTTLELIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNEMVQ
                     NFQDESCFVLSTIKAESNDGYHIILKCGL"
     exon            156..307
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            308..384
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            385..490
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            491..597
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            598..750
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            751..861
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            862..953
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1002
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1096
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1187
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1291
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1434
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1486
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..9287
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9264..9269
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /note="hexamer: AATAAA"
     polyA_site      9287
                     /gene="TFCP2L1"
                     /gene_synonym="CRTR1; LBP-9; LBP9"
                     /note="major polyA site"
ORIGIN      
        1 gggttcggag cgcgaagccg ccgctgggtc ctcggcgcgc cccgcgtctg cgcttgctgc
       61 cgcgccccgg tcggcgcgct gggagttcca gccatgctct tctggcacac gcagcccgag
      121 cactacaacc agcacaactc cggcagctac ctgcgtgatg tgctcgctct gcccatcttc
      181 aagcaggagg aaccccagct gtcccccgag aacgaggccc gcctgccacc cctgcaatat
      241 gtgttgtgtg ctgccacgtc cccagccgtg aagctgcatg aagagacgct gacctacctc
      301 aaccaaggtc agtcttatga aatccgacta ctggagaatc ggaagctggg agactttcaa
      361 gatctgaaca caaaatatgt caagagcatc atccgtgtgg tcttccatga ccgccggctg
      421 cagtatacgg agcaccagca gctggagggc tggcggtgga gtcggccagg ggaccggatc
      481 ctggacatcg atattccact gtctgttggt atcttggacc ccagggccag cccgacccag
      541 ctgaatgcag tcgagttttt gtgggaccct gcgaagagag cttctgcatt cattcaggta
      601 cactgcatca gcacagaatt cacccccagg aagcacgggg gcgagaaggg agtgcccttt
      661 cgagtccaga ttgacacgtt taagcagaac gagaatgggg agtacacgga gcacctgcac
      721 tcagccagct gccagatcaa ggtgttcaag ccgaagggag ccgatcggaa acagaagact
      781 gaccgggaga agatggagaa aagaactgcc caagagaagg agaaatacca gccgtcctat
      841 gaaaccacca tcctcacaga gtgctctcca tggcccgacg tggcctacca ggtgaacagc
      901 gccccgtccc caagctacaa tggttctcca aacagctttg gcctcggcga aggcaacgcc
      961 tctccgaccc acccggtgga ggccctgccc gtgggcagtg accacctgct cccatcagct
     1021 tcgatccagg atgcccagca gtggcttcac cgcaacaggt tctcgcagtt ctgccggctc
     1081 tttgccagct tctcaggtgc tgacttgctg aagatgtccc gagatgattt ggtccagatc
     1141 tgtggtcccg cagatgggat ccggctcttc aacgccatca aaggccggaa tgtgaggcca
     1201 aagatgacca tttatgtctg tcaggagctg gagcagaatc gagtgcccct gcagcagaag
     1261 cgggacggca gtggagacag caacctgtct gtgtaccacg ccatcttcct ggaagagctg
     1321 accaccttgg agctgattga gaagatcgcc aacctgtaca gcatctcccc ccagcacatc
     1381 caccgagtct accggcaggg ccccacgggc atccatgtgg tggtgagcaa cgagatggtg
     1441 cagaacttcc aagatgaatc ctgttttgtc ctcagcacaa ttaaagctga gagcaatgat
     1501 ggctaccaca tcatcctgaa atgtggactc tgagcagcag tggacctcat acctgtctcc
     1561 agctcccagc cctgtggatc cccgtggatg tagacattgc cccactgtaa gctgtggcct
     1621 caccaggcaa gctgaggcca ggagggaccc tgcccagtct gtgaaagcta cagagcacca
     1681 accagcagaa gcctgtggac accaagtacg gtgtacagaa agccagtggc tcctttctcc
     1741 cttcctcttg gcctccagat tttgaatggt tccttgttct tttctattgg tccaaccctg
     1801 acgttctaaa agggcaaaca gtggagacgt ctgctctgaa atccctcatc ccttagttgg
     1861 aagctgattg ggtatcttgg tgctgcctgt attggtccct tctgaccact ctcctgcctc
     1921 cagagaaagc tctgcttcac cctggaagct ggtaccttta cctcctcctc tgggagttgg
     1981 ctgcatggcc agcactgccg acttgatggg agcagtttgc cctcattctc ctgtttcagg
     2041 tttgcttccc ttctcagtga ccctggtgag catccgcctt tcctgttctt ggatgaattg
     2101 atgggagtgg ggctattctg tgccttctac ctctttcttc tctacgttgt ttctaaggat
     2161 ctgctgctgc ggaacccaaa gatgtgctcc tgtctctgca ctggcgcatt ggcatggtag
     2221 atgccacaat gtatgtgcac ggcctttctc agagacatta gttctgaggc cctttgtggg
     2281 gaggttaggg ggatggtaat agaaaaagac tattttattt cctggcaatc acgggtaagg
     2341 aggattagga atgagtattc cattcctagg tgtcatcaga tgaccttgac caccacaata
     2401 ccaggccctc ttggatggac ttatagaaag ttagagaaga ccttgttgaa ccgctgctaa
     2461 acttgccaca ggagcgatgt gttttctctg agtgcccctc acttacatgt ttatctttgt
     2521 ttgtagaggc tatgtttagg atattttgcc tgcatcagaa tgggtgcatc atctttctta
     2581 atggcctaac tatcgggaaa tttgagtgtc agtaactgtg gtagactcag aaattcgtct
     2641 ttgtcttgcc tctggttcct gggatccagt gatctctact ggcccagggc ttcagctctt
     2701 ggttaattta ggttcatggg gaaccctctg accacctgaa tgggatgtca tagcttctaa
     2761 atggagcttc tgtggaatga agtgctagac tgaaggacta ccagaataaa acagggtcta
     2821 caatggggag aacttgtttt atagatgagg aaaccaaggc tcagaggggc aaagtcacct
     2881 gcatggtagc acatagtgat agggtagcga tataaattta tcatataaac caggacatct
     2941 cggaataaaa ggggctctgt tagtcattat gttgggtaat agccgtggca ttcctacaga
     3001 acagagtgag gacaggctcc tgattcctct tccttcttta gaggagaagc ggggagtggg
     3061 ttaactaaca gctttattga gatgtcattc acatgccatt cagtttaccc attgctagtg
     3121 tccaattgta ttcacagaac caccatcaat tcacagaatt acagtcaacg ttggtacatt
     3181 ttcatcaccc ccagtaaaac cccgtaccct tggtctgtca ctcctgcttt cctaactcct
     3241 gcagtccaag gcagccatga atctactttc tatgtaagat taacctactc tggacatttc
     3301 atatatctgg aatcatgtga tatctctttt gtgactggct tcttccactg aatgttttct
     3361 agggccgtcc aagttgagga tgtatcagta cttcattctt ttgtattgct gaataatact
     3421 tcattgtata gatagaccac atttgtttat tgattcatca gttgatggac atttgtgtgt
     3481 ttttactttt tggctactct gaatgatgct gctatgaaca tatttctaca agattttgtg
     3541 tggacatatg ttttcatttc ttttagcaat atacatagga gtggaattgc taggtcttac
     3601 agtaactccg tgttttaact ttttgagaaa ctgccagact gttttctata gcagctgtac
     3661 cattttacat tcccaccagc aatgtatcca ggtttcaatt tgtctacatc ctcatcaaca
     3721 cttgctatta tctgtctttt tgcttttagc atcctaatga gtatgaaatg ctatcttgtg
     3781 gttttgattt gcattcccct gatggcaact gatgctgagt gtcttttcct gtgcttacgg
     3841 gccatgcgta tttctttgga gaaaggtcta tccaggtcct ttgcctattt ttaattgagt
     3901 tgtctttttt tttttaagtt ttctgttttc ctaaccacta gactaccagg gatgagcctt
     3961 ctttttatta ttgagttggg tgagctattt gtatattcta gacgccagtc ttttatcagg
     4021 tatatgactg gtaaaaatgt tctccccttc tgtggattgt tttcagtttc ttgttggtgt
     4081 cctttgagac acaaaacttt ttaactttga tgatttccaa gatacgtatt ttttttctat
     4141 tgtcacttgt gcttttggtg ccatatctag aaaaccattg cctaatccaa ggtcaagaag
     4201 attaatgcct gtgttttctt ctaagaacta tacttttagt tctcacaatg gtctttgatc
     4261 catttcgagt atatttttat atatgatgtg atgtaggggt ccagcttcat tcttttgctt
     4321 gtggatctcc acttgtccca ctgctgatta ttgagaaaaa tatcctttct ccacggaatt
     4381 gtcttggcat ccttgctaaa ggcctctgct tcttactgga tcttctttcc tgggacatgg
     4441 tgtcgttggg aagcttacct tttttttttt tttacttagt ctgtgtttgg ttccaccagt
     4501 tttatgctgc ctttctactc tgttcttgct gtctccctct ttacctgagt caacggtact
     4561 gagtcctatc tctctctgat gttccccagt cttccttggt gcatgttcta gctccacaca
     4621 ctagtccttg gaggaaggtt gagaccaatg atttcctgtt atgagtcatg aggaaactga
     4681 atcacctaga agtggaataa tgtgctcagg gtcaccatag cccattagtg gaaggaccag
     4741 gactagacct ttagtcttct gaggtccagc cccttaggct gtctgtcatc actgtaccca
     4801 agtgatgtca ctaccaaggc caaatgatgg tgggctaaat tttaattctc aaaagtgtag
     4861 gaggctaata ttgtcttcta agttccaaaa gaagatgtaa taaaagtctg ttaccttaag
     4921 tgtgctatta gtagagtctt ccatttttct ggcatgcccc tggcatctgc tcttcttacc
     4981 ttctcgtggt tgtagttaaa gcttatagct tatgaaagaa tagaaaataa taaataccaa
     5041 aaaaaagtac acatggtaat ttggtaccaa aatatctcag ctgcctaatt tagcagctca
     5101 tcccttccac aggggtcaga tgagctaaag ctccaggttt tatttttcat ttgattgaca
     5161 tacagaaaag ccatagccct tcccacagct gtccagggtc tttcctgtga gtccggaggt
     5221 gctggcctat tgagcaggac agctcttccc agggcattcc caccaacctg tggcttctga
     5281 actgtagctt ctttttacag tgaaccccag agggaaataa gacagacaca tgtgctcagg
     5341 ccaccatctt gaactggaag cccaaagctg agttccttac tcttaggtcg tcacggtttt
     5401 tgcggggtat ctgcaaggtt gagataaacc ctttcctgtt taccaggttg tcctttctgg
     5461 atgaagggac agaggctgtt gaatggagga ataataggtt tgctggagga ggggcatggt
     5521 atgcctgtgg aaaggacagg atggggtggg gaggtcgagg ctttgacttg gggtcctaaa
     5581 caaaggtcag gtgttgccct agtgacctct tgcccagaca gcccagagcc ccttacacag
     5641 agctattaac ctagggaagg ctttaccagc agtggactgg agccagccag ggtcacaagt
     5701 ttccaagtcc agcattgctt caggggctgg cctgagtaac tgaagatctg aaaatcatta
     5761 acaagtcgat gaaataaacg gaaaagcctc ttaggctgtt gtcagtggag cagagggaga
     5821 aagtccctag gcgctcagag ggggtgagaa agcagtggat gattgggcgg gggtggggga
     5881 ttagatgttg acactgcctg gggtgtagga agaggaacag agaacccaga gtcagggtcc
     5941 tagatcccag accctcgctc agtatgagtc tctttgcctc tctgggtctc tatctcctcc
     6001 tcttacaaat acaggcttgg tgatctctga agatggcacc aacctgccat gaaatgaatc
     6061 tgaggggttt tcccattttt ccctccatca aaatcgtaca aaaagctgga cgtggtggcc
     6121 catgcctcta atcctagcat tttgggaggc cgaggtggga gaatcacttg acgccaagag
     6181 ttcgagacca gcctgggcat cgtagtgaga ctccatctct gtctttttga aaataaaaaa
     6241 tctttgaaaa ttgcacaaca ggcaggagac ctttacgtgt gcccatcctg gttgtacaca
     6301 gtgccaccag tgctcctgca gtgcaaggcg gcatgcttct tgacatgggt cagattgtgt
     6361 ccatcgtgtc tttgggaatc agccctagct cctaactggg ctgactactt cctccgcaaa
     6421 cttatggggg ctcccagata ttccttgcca gccaggggcc agacacagtg caggcacagt
     6481 ctgtgtcatt ggtgcacatg tgcgtgttta catgtgtacc tgggttcctt cccttgccca
     6541 tgaatttgcc atgagcacag ccagaagcag cctcagcttg gcaaggtgtg gagatgactg
     6601 ctgttccctt cgcatttggg gaaaacaggc tccctcggta gctcgatgat cctcttttga
     6661 tcttgtgtga cctcctggag agtggatgaa gctggtggcc ttagcttttc tagacagtgt
     6721 aagtggcact gggcaaggcc cccagagcag ggcaaggtct ctagagcggg tctcccacat
     6781 gactggcttc acacaggcac ttccgctcgg gttgcatgct ctgtgtcatc ttaccggtcc
     6841 agggttgcag gtaggaaatg tttgtaccct cttctgattg ccacctcctt cccatcgccc
     6901 cttagggaca gggcttgagg gccagtgagg cgctggtcag gcaccccagg cctccttggg
     6961 acctgcccag gggcaccctg agagctcctg aaacccccac ttagcttcca gacctttctg
     7021 caaaagctcc tcctggcttt cctccctccc ccaatctatg ggtcacagct aacagatctg
     7081 agggcaactg ctgtgctagt ggccagggct gcacctgcca tccccggctc tgccacttta
     7141 gggccttcta gaggcagtgt ccttaggaag tagctctgag gcatgggttt tctgctcctg
     7201 tgcagggcag ctgatgggat aaggtgggga aggacggtca gtgcttgggc cccagctggc
     7261 cagcctggcg atggggaaac caaaccatgt cccccagcga agggccagag tgggaacctg
     7321 tcctcatgcc cttcgtcctg aggagccctg aggtgggcag caggggccag gggaagtttt
     7381 caggccttca tcaaagagaa caacatcctc agctccgcac ccctcatcct gtatcagcac
     7441 ttaccggtgt gtgactgccc ttgtcagcta gcatacggtg ggcccacctg gcccactggc
     7501 tgtttatgcc actgatttat gatagggaat attatctttg aacccaatga agtgttttct
     7561 cccccatcac aaaaaaaaaa attcttattt ttagtagaca tgtatttacc aaaaatatgt
     7621 actcaattat tgtattttgg attttatcaa tttaaaaatt gtggaaattt gtttgctctt
     7681 acgccaacat aatattgatt ttgcctcttg gctctgaaag cccaaaatat ttaccgtcta
     7741 gcccgttaca gaaaaagtct gctgactact gagccagacc tccattacct ccatccctgt
     7801 tggattattt aaagaaagcc tcagacagta agggcttttt taaaagaata aaatgacttg
     7861 gtttgcgctt ggaagcaggg gaagcattca gatgagcggt ttctgcatta accctgccta
     7921 tcacgcatct cgtgtcctgt gtggctggcg agcccccctt ggaaggttct ggtgcttcag
     7981 ctggctcctg cagagtccac cccgcctcgt ggtgggaatg cagagccctt tgctttcctt
     8041 cttgccgcct gcttcctgtt cctggggacc cgctgggcct ttggtctgca tcccctggcc
     8101 aggtccctca gggttgatgc gtggagaagg actttgagca gtggtgggca gcagtggcct
     8161 cctggccagc tcacactctt gtcctgggag gggcagcctg atctcacctc cacctagtac
     8221 cttggggact gaggaccttt tggcttctct ggagcctgca agcctcttcc catgtgtcca
     8281 gctgctcttc ctgctacaaa ggggactgct cacagtggcc tcagcttggt ggttttgagg
     8341 ggccgccccc cggccctcca taagggtatc ctgggcctga gaattctgca tctgccattg
     8401 gaggatggac agcctcaaat ggaaggagtc ccacgggaga tgggtccgag gtccggctgt
     8461 ggccatccag ccccctgtgg cttgtccagc ctctgtgcac ccctggtgtc ttcactccag
     8521 gggcagacag cagccactgc agttcctttc ttcgtgagta acagtagtga tagcagctgg
     8581 ggctaacagg ctaggctttg tgttctgcgc atttggtcag cttctcactc gatcctccct
     8641 aaagcaatgg ggaggccccc actagcccag ttttcaggaa gtcaactggg aggttagatg
     8701 ggggccaggg tcccacagct actgatggcc cgagccaggt tgagcttcct ggtgtccagt
     8761 ccggatccca cttgcagatc tcatgctctc agataggtgg gacaagttct tttgtcacag
     8821 tgctggctct gtcctgaggc ctcattgctg gctgggtgtg ctctgctggg aaaagctttg
     8881 cggggcttgc ttggttaacc acagaagaga aggggactgt ttggggtgcc tctctgcagc
     8941 ctccccgtgc tgggtggaag cacggttact gtgttctcta atgttcatgt atttaaaatg
     9001 atttctttct aaagatgtaa cctccacacc tttctccaga ttgggtgact cttttctaaa
     9061 ggtggtggga gtatctgtcg gggtggtgtg gcccttggat gggtcaggtg ggtgtgagag
     9121 gtcctgggga ggtgggcgtt gagctcaaag ttgtcctact gccatgtttt tgtacctgaa
     9181 ataaagcata ttttgcactt gttactgtac catagtgcgg acgagaagtc tgtatgtggg
     9241 atctgtgctt gggttagaat gcaaataaaa ctcacatttg taagaaa
//
