LOCUS       NM_001128202             941 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens testis expressed 36 (TEX36), transcript variant 1,
            mRNA.
ACCESSION   NM_001128202
VERSION     NM_001128202.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Chalasani,N., Guo,X., Loomba,R., Goodarzi,M.O., Haritunians,T.,
            Kwon,S., Cui,J., Taylor,K.D., Wilson,L., Cummings,O.W., Chen,Y.D.
            and Rotter,J.I.
  CONSRTM   Nonalcoholic Steatohepatitis Clinical Research Network
  TITLE     Genome-wide association study identifies variants associated with
            histologic features of nonalcoholic Fatty liver disease
  JOURNAL   Gastroenterology 139 (5), 1567-1576 (2010)
   PUBMED   20708005
REFERENCE   2  (bases 1 to 941)
  AUTHORS   Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M.,
            French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S.,
            Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G.,
            Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P.,
            Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K.,
            Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C.,
            Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P.,
            Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N.,
            Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A.,
            Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C.,
            Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E.,
            Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E.,
            Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M.,
            Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M.,
            Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J.,
            Lovell,J., McLaren,S., McLay,K.E., McMurray,A.,
            Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T.,
            Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I.,
            Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A.,
            Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
            Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A.,
            Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J.,
            Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L.,
            Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C.,
            Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R.,
            Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 10
  JOURNAL   Nature 429 (6990), 375-381 (2004)
   PUBMED   15164054
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL158835.11, BC062717.1 and AA977508.1.
            
            On May 17, 2019 this sequence version replaced NM_001128202.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.30863.1, BC062717.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000368821.4/ ENSP00000357811.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                AL158835.11        90345-90363         c
            20-935              BC062717.1         4-919
            936-941             AA977508.1         3-8                 c
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q26.13"
     gene            1..941
                     /gene="TEX36"
                     /gene_synonym="bA383C5.1; C10orf122"
                     /note="testis expressed 36"
                     /db_xref="GeneID:387718"
                     /db_xref="HGNC:HGNC:31653"
     exon            1..225
                     /gene="TEX36"
                     /gene_synonym="bA383C5.1; C10orf122"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..735
                     /gene="TEX36"
                     /gene_synonym="bA383C5.1; C10orf122"
                     /note="isoform a is encoded by transcript variant 1;
                     testis-expressed sequence 36 protein; testis-expressed
                     protein 36"
                     /codon_start=1
                     /product="testis-expressed protein 36 isoform a"
                     /protein_id="NP_001121674.1"
                     /db_xref="CCDS:CCDS44493.1"
                     /db_xref="GeneID:387718"
                     /db_xref="HGNC:HGNC:31653"
                     /translation="MTKGRRFNPPSDKDGRWFPHIGLTQKTPESITSATSKEPQSPHL
                     PRQAEGKLPPIYKVREKQAVNNQFPFSVHDNRHSLENSGCYLDSGLGRKKISPDKRQH
                     VSRNFNLWACDYVPSCLDGFSNNQISYVYKEAMVVSSFRRFPRCYKEIWNAFTFLPER
                     SYTEVLKKKPKVRFTVDKKVVSSLES"
     exon            226..357
                     /gene="TEX36"
                     /gene_synonym="bA383C5.1; C10orf122"
                     /inference="alignment:Splign:2.1.0"
     exon            358..438
                     /gene="TEX36"
                     /gene_synonym="bA383C5.1; C10orf122"
                     /inference="alignment:Splign:2.1.0"
     exon            439..941
                     /gene="TEX36"
                     /gene_synonym="bA383C5.1; C10orf122"
                     /inference="alignment:Splign:2.1.0"
     regulatory      915..920
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TEX36"
                     /gene_synonym="bA383C5.1; C10orf122"
                     /note="hexamer: AATAAA"
     polyA_site      941
                     /gene="TEX36"
                     /gene_synonym="bA383C5.1; C10orf122"
                     /note="major polyA site"
ORIGIN      
        1 acccgcacct tcccctcctg gaagaggctg agaagtaaag atcaggaaca aggaggagga
       61 ggagcttccc agacgtgtag agcttatgaa gtttaggaag cagcttccca gacatgtaga
      121 gcttatggag aggtgaggga gccaatctca gccacattca gcttcctgga gagaatgacc
      181 aaagggcgac gcttcaaccc accttcagac aaggatggga gatggttccc tcacatcggg
      241 ctaacgcaaa agacaccaga atccatcacc agtgctacgt caaaagagcc ccagagtcca
      301 cacttgcctc ggcaagcgga ggggaagctg ccgcccatat acaaagtccg ggagaagcaa
      361 gcagtgaata accagttccc cttctccgtg catgacaatc ggcacagctt ggagaactct
      421 ggatgctacc ttgactccgg cctgggacgt aagaagatct ctccagataa gaggcaacat
      481 gtttcaagaa attttaatct ctgggcatgt gactatgttc catcttgtct tgatggcttt
      541 tcaaataacc aaatatcata cgtatataaa gaagccatgg tggtctcaag cttcagacgc
      601 tttccacgat gctataaaga gatatggaac gcttttacat ttcttcctga gagaagctat
      661 acagaggttt tgaaaaagaa gcccaaagta aggttcactg ttgacaaaaa ggttgtttct
      721 tcactggagt cctaatcctc ccagaagatt tttgatgaat tttgtaatac tggtatttca
      781 tcagacatcc taaaagtata tgttttctga tccagcacca ctatttaatt tttaaagtac
      841 ttttatgatt tttataaggt caaaaaacat tcaaatcctt gtgaaatgaa tttgtgatga
      901 catacgcatg tgtaaataaa cttttcagat ggccacattt a
//
