LOCUS       NM_001586               1566 bp    mRNA    linear   PRI 22-SEP-2024
DEFINITION  Homo sapiens testis expressed 28 (TEX28), transcript variant 2,
            mRNA.
ACCESSION   NM_001586
VERSION     NM_001586.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1566)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 1566)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 1566)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 1566)
  AUTHORS   Metlapally,R., Michaelides,M., Bulusu,A., Li,Y.J., Schwartz,M.,
            Rosenberg,T., Hunt,D.M., Moore,A.T., Zuchner,S., Rickman,C.B. and
            Young,T.L.
  TITLE     Evaluation of the X-linked high-grade myopia locus (MYP1) with cone
            dysfunction and color vision deficiencies
  JOURNAL   Invest Ophthalmol Vis Sci 50 (4), 1552-1558 (2009)
   PUBMED   19098318
  REMARK    GeneRIF: TEX28 gene CNVs (copy number variations) appear to be
            associated with the MYP1 X-linked myopia phenotypes.
REFERENCE   5  (bases 1 to 1566)
  AUTHORS   Denoeud,F., Kapranov,P., Ucla,C., Frankish,A., Castelo,R.,
            Drenkow,J., Lagarde,J., Alioto,T., Manzano,C., Chrast,J., Dike,S.,
            Wyss,C., Henrichsen,C.N., Holroyd,N., Dickson,M.C., Taylor,R.,
            Hance,Z., Foissac,S., Myers,R.M., Rogers,J., Hubbard,T., Harrow,J.,
            Guigo,R., Gingeras,T.R., Antonarakis,S.E. and Reymond,A.
  TITLE     Prominent use of distal 5' transcription start sites and discovery
            of a large number of additional exons in ENCODE regions
  JOURNAL   Genome Res 17 (6), 746-759 (2007)
   PUBMED   17567994
REFERENCE   6  (bases 1 to 1566)
  AUTHORS   Ueyama,H., Torii,R., Tanabe,S., Oda,S. and Yamade,S.
  TITLE     An insertion/deletion TEX28 polymorphism and its application to
            analysis of red/green visual pigment gene arrays
  JOURNAL   J Hum Genet 49 (10), 548-557 (2004)
   PUBMED   15378397
  REMARK    GeneRIF: proposed a structure of the second gene of 3-gene arrays,
            Green-pTEX-Green-pTEX-Green-fTEX and Red-pTEX-Red-pTEX-Red-fTEX, in
            color-vision-deficient subjects
REFERENCE   7  (bases 1 to 1566)
  AUTHORS   Hanna,M.C., Platts,J.T. and Kirkness,E.F.
  TITLE     Identification of a gene within the tandem array of red and green
            color pigment genes
  JOURNAL   Genomics 43 (3), 384-386 (1997)
   PUBMED   9268643
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC245140.2.
            
            On Jun 26, 2021 this sequence version replaced NM_001586.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U93720.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000617225.5/ ENSP00000482010.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                AC245140.2         125824-125918
            96-195              AC245140.2         128743-128842
            196-923             AC245140.2         132541-133268
            924-1059            AC245140.2         148422-148557
            1060-1566           AC245140.2         149177-149683
FEATURES             Location/Qualifiers
     source          1..1566
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq28"
     gene            1..1566
                     /gene="TEX28"
                     /gene_synonym="CXorf2; fTEX; MRX99; TEX28P1; TEX28P2"
                     /note="testis expressed 28"
                     /db_xref="GeneID:1527"
                     /db_xref="HGNC:HGNC:2563"
                     /db_xref="MIM:300092"
     exon            1..95
                     /gene="TEX28"
                     /gene_synonym="CXorf2; fTEX; MRX99; TEX28P1; TEX28P2"
                     /inference="alignment:Splign:2.1.0"
     exon            96..195
                     /gene="TEX28"
                     /gene_synonym="CXorf2; fTEX; MRX99; TEX28P1; TEX28P2"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..1416
                     /gene="TEX28"
                     /gene_synonym="CXorf2; fTEX; MRX99; TEX28P1; TEX28P2"
                     /codon_start=1
                     /product="testis-specific protein TEX28"
                     /protein_id="NP_001577.1"
                     /db_xref="CCDS:CCDS14744.2"
                     /db_xref="GeneID:1527"
                     /db_xref="HGNC:HGNC:2563"
                     /db_xref="MIM:300092"
                     /translation="MVLKAEHTRSPSATLPSNVPSCRSLSSSEDGPSGPSSLADGGLA
                     HNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADRHQVPHIQQAFEKVNQRA
                     SATIAQIEHRLHQCHQQLQELEEGCRPEGLLLMAESDPANCEPPSEKALLSEPPEPGG
                     EDGPVNLPHASRPFILESRFQSLQQGTCLETEDVAQQQNLLLQKVKAELEEAKRFHIS
                     LQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACS
                     EERMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQSRPPQMLFKFLSP
                     RLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQEWV
                     PSRCRLYSKDSGPPADGP"
     exon            196..923
                     /gene="TEX28"
                     /gene_synonym="CXorf2; fTEX; MRX99; TEX28P1; TEX28P2"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1059
                     /gene="TEX28"
                     /gene_synonym="CXorf2; fTEX; MRX99; TEX28P1; TEX28P2"
                     /inference="alignment:Splign:2.1.0"
     exon            1060..1566
                     /gene="TEX28"
                     /gene_synonym="CXorf2; fTEX; MRX99; TEX28P1; TEX28P2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatgtgctc gccctgtgtc tgaaatgccc catgtccggt ggtgccagca ctagccccca
       61 tgtcggtctc agagaacctt ctccccacct ctgagttatt ctctcagtgt atcgaagata
      121 tcagtcaact atcttctgga ttgcattgat gctattgaga aggcagcctg cagtctaaaa
      181 gtcatggttt taaaggcgga acacaccagg agccccagcg caaccctccc ctccaatgtg
      241 ccttcatgcc ggtccctgtc atccagcgaa gacggcccca gtggcccttc cagcctcgca
      301 gatggaggcc tagcccacaa cttacaggat agtgtcaggc accgcatcct ctacctctca
      361 gagcagctga gagtggagaa ggccagtcgg gatggcaaca ctgtgagcta cctcaagctg
      421 gtatccaaag cagaccggca ccaggtgccg cacatccagc aggcctttga gaaggtgaac
      481 cagcgcgcct ctgccaccat cgcccagatc gagcacaggc tccaccagtg tcaccagcag
      541 ctccaggagc tggaggaagg ctgcaggccc gagggcttac tgctgatggc agaaagcgac
      601 ccagccaact gcgagccacc cagtgagaag gccctgcttt cagagccccc cgagccaggt
      661 ggggaagacg ggccggtcaa cctgcctcat gccagcaggc ccttcatctt ggagagtcgc
      721 ttccagagct tacagcaggg gacgtgctta gagacagagg atgtggccca gcaacaaaac
      781 ctgctgttgc agaaggtaaa ggcagagctg gaagaagcca agaggttcca catcagcctc
      841 caggagtcct atcacagcct aaaggagagg tctctgactg acctgcagct gttgctggag
      901 tcccttcagg aggagaagtg taggcaagca ttgatggaag aacaggtgaa tggtcgcctg
      961 cagggacagc tgaatgagat ttacaacctc aaacacaatc tggcctgcag cgaagagaga
     1021 atggcctatc tatcctatga gagagccaag gaaatatggg agatcacgga gaccttcaag
     1081 agccgaatat ccaagctgga gatgctacag caagtcaccc aactggaggc agcggagcac
     1141 ctccaaagcc gtcccccgca gatgttgttc aagttcctga gtccgcgcct ctcactggca
     1201 accgtcctct tggtctttgt ctccaccttg tgtgcctgcc cctcgtcact gatcagctca
     1261 cgcctgtgca cctgcaccat gctgatgctg atcgggcttg gggtcctggc ctggcagagg
     1321 tggcgcgcca tccctgccac agactggcag gaatgggtcc cctccaggtg tagactgtac
     1381 tccaaggact ctgggcctcc agcagatgga ccttaagggg ccaggagggc cacctgcctt
     1441 agcttgctag ctccctccct cctcctgggt gctgagggca tccagcaagc ccctccacag
     1501 ctcttgcttg ccgattatgt aaccaccagc ctggtgaaat ggatatagac gcccacctgc
     1561 ctcaca
//
