LOCUS       NM_144582               3365 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens testis expressed 261 (TEX261), mRNA.
ACCESSION   NM_144582
VERSION     NM_144582.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3365)
  AUTHORS   Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
            Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
            Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
            Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
            Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
            Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
            Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
            Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
            Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
  TITLE     The secreted protein discovery initiative (SPDI), a large-scale
            effort to identify novel human secreted and transmembrane proteins:
            a bioinformatics assessment
  JOURNAL   Genome Res 13 (10), 2265-2270 (2003)
   PUBMED   12975309
  REMARK    Erratum:[Genome Res. 2003 Dec;13(12):2759]
REFERENCE   2  (bases 1 to 3365)
  AUTHORS   Lopez-Fernandez,L.A., Parraga,M. and del Mazo,J.
  TITLE     Tex261, a novel gene presumably related but distinct from
            steroidogenic acute regulatory (StAR) gene, is regulated during the
            development of germ cells
  JOURNAL   Biochem Biophys Res Commun 242 (3), 565-569 (1998)
   PUBMED   9464256
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC007040.2, BI552105.1, BC010656.1, AK056410.1 and BC020251.1.
            
            On Nov 22, 2018 this sequence version replaced NM_144582.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY358783.1, SRR1803612.98875.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000272438.9/ ENSP00000272438.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC007040.2         143044-143045       c
            3-536               BI552105.1         6-539
            537-2263            BC010656.1         173-1899
            2264-2831           AK056410.1         2480-3047
            2832-3365           BC020251.1         2583-3116
FEATURES             Location/Qualifiers
     source          1..3365
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p13.3"
     gene            1..3365
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /note="testis expressed 261"
                     /db_xref="GeneID:113419"
                     /db_xref="HGNC:HGNC:30712"
                     /db_xref="MIM:618562"
     exon            1..186
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..707
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /note="testis expressed sequence 261"
                     /codon_start=1
                     /product="protein TEX261"
                     /protein_id="NP_653183.2"
                     /db_xref="CCDS:CCDS1914.1"
                     /db_xref="GeneID:113419"
                     /db_xref="HGNC:HGNC:30712"
                     /db_xref="MIM:618562"
                     /translation="MWFMYLLSWLSLFIQVAFITLAVAAGLYYLAELIEEYTVATSRI
                     IKYMIWFSTAVLIGLYVFERFPTSMIGVGLFTNLVYFGLLQTFPFIMLTSPNFILSCG
                     LVVVNHYLAFQFFAEEYYPFSEVLAYFTFCLWIIPFAFFVSLSAGENVLPSTMQPGDD
                     VVSNYFTKGKRGKRLGILVVFSFIKEAILPSRQKIY"
     exon            187..266
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /inference="alignment:Splign:2.1.0"
     exon            267..420
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /inference="alignment:Splign:2.1.0"
     exon            421..488
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /inference="alignment:Splign:2.1.0"
     exon            489..591
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /inference="alignment:Splign:2.1.0"
     exon            592..3365
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3345..3350
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /note="hexamer: AATAAA"
     polyA_site      3365
                     /gene="TEX261"
                     /gene_synonym="TEG-261"
                     /note="major polyA site"
ORIGIN      
        1 ctgtcgtccg cggggcgggg acgcggcggc ggcggcggcg gtggcggctg tgtgtcgccg
       61 gagccgaagc gcgcaggccc gtcccggtgg ccggggagcg ggcgggtggg ggcgccatgt
      121 ggttcatgta cctgctgagc tggctgtcgc tcttcatcca ggtggccttc atcacgctgg
      181 ctgtcgcggc tggactctat tacctggcag aactgataga agaatacaca gtggccacca
      241 gcaggatcat aaaatacatg atctggttct ccaccgctgt actgattggc ctctacgtct
      301 ttgagcgctt ccccaccagc atgattggag tgggcctatt caccaacctc gtctactttg
      361 gcctcctcca gaccttcccc ttcatcatgc tgacctcgcc taacttcatc ctgtcgtgtg
      421 gactagtggt ggtgaatcat tacctagcat ttcagttttt tgcagaagaa tattatccct
      481 tctcagaggt cctggcctat ttcactttct gcctgtggat aattccgttt gcgttttttg
      541 tgtcactttc ggccggggag aacgtcctgc cctctaccat gcagccagga gatgatgtcg
      601 tctccaatta tttcaccaaa ggcaagcggg gcaaacgctt agggatcctg gttgtcttct
      661 ccttcatcaa agaggccatt ctacccagtc gtcagaagat atactgaccc ccatgcaggc
      721 aggatgtggg gggcaagatc aggagagtca ggcccctggg cctctatgcc aggtggggac
      781 cagaagtcgg gaaggcacct accacctgcc ctggctttct tcccctcaac tctggagccc
      841 catccccacc ctccttgggg ggctcagctt ggctcagatc tgatgcttca agaggctgta
      901 acctcagagg gcaccaagga gggtggcaga gcctgcttag ccaggaggcc gaggtccctc
      961 agtcctcccc tgtcccttcc aaggtgggtc aggaggttct ggccccgctg gggcaggcag
     1021 ggcagggtct gtgaagctta agagcagatg gtgacaagtt ctctgggcag gtggccatgg
     1081 ggaggggcca tggcttggca tgtccaacag aaatagtttt tgctgttgaa cggtgatttc
     1141 tgtccaagtg cagatttccg tttgaataaa gcttcgcttc taggtggcac tgtttgcctt
     1201 aataccctga cagttcatct tcctttcttc ctgctaacct tctgctctgg actggactca
     1261 cttttctgct ccagggactc cttttctggg tttgggtctt gcccttccca agggactgtt
     1321 cttgtggccc ttaatgggaa gggggcaggg gtgaggagct gagcctgctc aaggagtggg
     1381 aagtggggct ataggcagcc tctctgatgc actctcttcc atctctttcc ccaaggctcc
     1441 gtgactgtca aactgggagt aggagagggg acaatttagg actgggctag attttcagaa
     1501 gaacatctac aatatcctat ttataaatct tcctctggga aaaggagtgg tttctggctg
     1561 aatactatct taggctcaag gagaaacaaa ataaaaatta gcttccaggc agcctgtttt
     1621 taaagaaatg ggactaatgg gagaagctgt ttgtcactct aagagcatcc aagccctggc
     1681 ccgtctgtgc actcttggct cctggggaga tatatctgcc ttctaagaag gcaggccagg
     1741 tcttgggcac agacctgcat ttgttgacct tgcactccaa ctatagtgcc ttgcaagtgc
     1801 tcaacagtac atattggaat gaagtcccta tgagagccat ttctggccat gttctatacc
     1861 tcaaagtgag gctggcaggt acagagatga actgtacaca tgtgatacat ttaagccact
     1921 ggaaaaaccc ctgtgcttga aaatatttcc tctatatcat gcctggagtt ccatcatagc
     1981 ccttcatttc cttggcttta gcatttacct tctcttaaga ataccagctt tcccctttcc
     2041 ctgagaggaa gagcacatgt tggtctcctc ttagtgtgaa cgagattgcc aggccctttt
     2101 ctcctatgca caccaggata gacaaggcag gggatactgg cagcctgcat catcctccca
     2161 ttgggctgac agctggccct actttcctcc ctctgctgct tggtccctca ccttgatgat
     2221 gtggcttcgc cccctccact ctactgccag tgttctccca gggcttgcta aatccagcag
     2281 acccctttcc tgtcttacta gatctgggca gcatttgaca tggctgatca ccccttgctt
     2341 cttggatggc acttccctgg cacctctgtg gctagttgtc ctacctccct ggctgttcct
     2401 ttcaggcttc cgtgcaggct tctccacttg cccatgcaca gtagggtctt tcagggttct
     2461 gctgtgggct ccctagggaa gcccatccat ctggatggtt tcaaggatgg tgaggaattt
     2521 agagttgacc tccagcccca acatccttcc tgatcacctg aaccacagtt ttgctgccct
     2581 ctaggtgcac agacaattca ggtccatggc ccagatggta cttgctgtct tctgcaaacc
     2641 tgccccttct gggtacttcc cttgaccccg agatcactca ggagccagac aggaaactta
     2701 ttctattcct gttttctctt tctgcccacc acatccaatc tctcaaaacg gtcaggtcta
     2761 ccttaacatc tcttgatttg agccactccc actgtcatca gctttcacct ggattatcgt
     2821 gacagcctcc tactgcttct ctatcatgtg gccagagcta tcttcctaaa atgcattgca
     2881 tagttgatca agtcactctc tggcctaaaa ccttccttgg ctccctgctg ccctcaggat
     2941 aaagtctgga cccctcagca tggcttgtga gactcatggt gtccttgtcc ctgctcacct
     3001 ctctggtctc atcacttgcc ttcttgcatt ctgggtccca gcctcctgta tccagagatg
     3061 cagtggctct ccattgccac tctgattcct cctttctttt ggtcacagag aaagggtact
     3121 ttctctgtca aatctcaact tagacttgac ttcctccaag gagctttggc tatactctct
     3181 cctcccgacc cccaccctgg catactacac agatcactct gggctcactt gcctgcctaa
     3241 tggtcatctc cccagtagac tgtaagctcc ttgagggcaa ggattgtgtt ggaatttttg
     3301 tattaacagt gcctggcttg gtgcctggca cctagaaagc actcaataaa tgtttgttta
     3361 atgaa
//
