LOCUS       NM_031272               4797 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens testis expressed 14, intercellular bridge forming
            factor (TEX14), transcript variant 2, mRNA.
ACCESSION   NM_031272
VERSION     NM_031272.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4797)
  AUTHORS   Cho,Y., Nam,Y., Lee,H.H. and Chang,R.
  TITLE     Inhibition mechanism of testis-expressed gene 14 (TEX14) in
            cytokinetic abscission: Well-tempered metadynamics simulation
            studies
  JOURNAL   J Chem Phys 159 (1) (2023)
   PUBMED   37409705
  REMARK    GeneRIF: Inhibition mechanism of testis-expressed gene 14 (TEX14)
            in cytokinetic abscission: Well-tempered metadynamics simulation
            studies.
REFERENCE   2  (bases 1 to 4797)
  AUTHORS   Mihalic,F., Simonetti,L., Giudice,G., Sander,M.R., Lindqvist,R.,
            Peters,M.B.A., Benz,C., Kassa,E., Badgujar,D., Inturi,R., Ali,M.,
            Krystkowiak,I., Sayadi,A., Andersson,E., Aronsson,H., Soderberg,O.,
            Dobritzsch,D., Petsalaki,E., Overby,A.K., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Large-scale phage-based screening reveals extensive pan-viral
            mimicry of host short linear motifs
  JOURNAL   Nat Commun 14 (1), 2409 (2023)
   PUBMED   37100772
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4797)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   4  (bases 1 to 4797)
  AUTHORS   An,M., Liu,Y., Zhang,M., Hu,K., Jin,Y., Xu,S., Wang,H. and Lu,M.
  TITLE     Targeted next-generation sequencing panel screening of 668 Chinese
            patients with non-obstructive azoospermia
  JOURNAL   J Assist Reprod Genet 38 (8), 1997-2005 (2021)
   PUBMED   33728612
  REMARK    GeneRIF: Targeted next-generation sequencing panel screening of 668
            Chinese patients with non-obstructive azoospermia.
REFERENCE   5  (bases 1 to 4797)
  AUTHORS   Buljan,M., Ciuffa,R., van Drogen,A., Vichalkovski,A., Mehnert,M.,
            Rosenberger,G., Lee,S., Varjosalo,M., Pernas,L.E., Spegg,V.,
            Snijder,B., Aebersold,R. and Gstaiger,M.
  TITLE     Kinase Interaction Network Expands Functional and Disease Roles of
            Human Kinases
  JOURNAL   Mol Cell 79 (3), 504-520 (2020)
   PUBMED   32707033
REFERENCE   6  (bases 1 to 4797)
  AUTHORS   Couch,F.J., Wang,X., Bamlet,W.R., de Andrade,M., Petersen,G.M. and
            McWilliams,R.R.
  TITLE     Association of mitotic regulation pathway polymorphisms with
            pancreatic cancer risk and outcome
  JOURNAL   Cancer Epidemiol Biomarkers Prev 19 (1), 251-257 (2010)
   PUBMED   20056645
  REMARK    GeneRIF: Observational study of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
REFERENCE   7  (bases 1 to 4797)
  AUTHORS   Kang,D., Oh,S., Ahn,S.M., Lee,B.H. and Moon,M.H.
  TITLE     Proteomic analysis of exosomes from human neural stem cells by flow
            field-flow fractionation and nanoflow liquid chromatography-tandem
            mass spectrometry
  JOURNAL   J Proteome Res 7 (8), 3475-3480 (2008)
   PUBMED   18570454
REFERENCE   8  (bases 1 to 4797)
  AUTHORS   Wu,M.H., Rajkovic,A., Burns,K.H., Yan,W., Lin,Y.N. and Matzuk,M.M.
  TITLE     Sequence and expression of testis-expressed gene 14 (Tex14): a gene
            encoding a protein kinase preferentially expressed during
            spermatogenesis
  JOURNAL   Gene Expr Patterns 3 (2), 231-236 (2003)
   PUBMED   12711554
REFERENCE   9  (bases 1 to 4797)
  AUTHORS   Manning,G., Whyte,D.B., Martinez,R., Hunter,T. and Sudarsanam,S.
  TITLE     The protein kinase complement of the human genome
  JOURNAL   Science 298 (5600), 1912-1934 (2002)
   PUBMED   12471243
  REMARK    GeneRIF: TEX14, also known as SgK307, contains a variant and
            probably inactive protein kinase domain and N-terminal ankyrin
            repeats.
            Review article
REFERENCE   10 (bases 1 to 4797)
  AUTHORS   Wang,P.J., McCarrey,J.R., Yang,F. and Page,D.C.
  TITLE     An abundance of X-linked genes expressed in spermatogonia
  JOURNAL   Nat Genet 27 (4), 422-426 (2001)
   PUBMED   11279525
  REMARK    GeneRIF: TEX14 is specifically expressed in testis
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DB086121.1, BK000998.1,
            CB044007.1 and AI243203.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 21, 2020 this sequence version replaced NM_031272.4.
            
            Summary: The protein encoded by this gene is necessary for
            intercellular bridges in germ cells, which are required for
            spermatogenesis. Three transcript variants encoding different
            isoforms have been found for this gene.[provided by RefSeq, Jan
            2011].
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice junction at the 5' end of an exon and lacks an alternate
            in-frame exon compared to variant 3. The resulting isoform (b) has
            the same N- and C-termini but is shorter compared to isoform c.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK000998.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000349033.10/ ENSP00000268910.8
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                DB086121.1         35-59
            26-4334             BK000998.1         1-4309
            4335-4795           CB044007.1         19-479              c
            4796-4797           AI243203.1         10-11               c
FEATURES             Location/Qualifiers
     source          1..4797
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q22"
     gene            1..4797
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /note="testis expressed 14, intercellular bridge forming
                     factor"
                     /db_xref="GeneID:56155"
                     /db_xref="HGNC:HGNC:11737"
                     /db_xref="MIM:605792"
     exon            1..107
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            108..244
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..4464
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /note="isoform b is encoded by transcript variant 2;
                     cancer/testis antigen 113; testis-expressed protein 14;
                     sugen kinase 307; protein kinase-like protein SgK307;
                     testis-expressed sequence 14 protein; inactive
                     serine/threonine-protein kinase TEX14"
                     /codon_start=1
                     /product="inactive serine/threonine-protein kinase TEX14
                     isoform b"
                     /protein_id="NP_112562.3"
                     /db_xref="CCDS:CCDS32692.1"
                     /db_xref="GeneID:56155"
                     /db_xref="HGNC:HGNC:11737"
                     /db_xref="MIM:605792"
                     /translation="MSRAVRLPVPCPVQLGTLRNDSLEAQLHEYVKQGNYVKVKKILK
                     KGIYVDAVNSLGQTALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQ
                     WILSKLLDAGGDLRLHDERGQNPKTWALTAGKERSTQIVEFMQRCASHMQAIIQGFSY
                     DLLKKIDSPQRLVYSPSWCGGLVQGNPNGSPNRLLKAGVISAQNIYSFGFGKFYLTGA
                     TQMAYLGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNGSRVTVKELNLPTHPH
                     CSRLRLADLLIAEQEHSSKLRHPYLLQLMAVCLSQDLEKTRLVYERITIGTLFSVLHE
                     RRSQFPVLHMEVIVHLLLQISDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYM
                     LESEDRGVQRDLTRVPLPTQLYNWAAPEVILQKAATVKSDIYSFSMIMQEILTDDIPW
                     KGLDGSVVKKAVVSGNYLEADVRLPKPYYDIVKSGIHVKQKDRTMNLQDIRYILKNDL
                     KDFTGAQRTQPTESPRVQRYGLHPDVNVYLGLTSEHPRETPDMEIIELKEMGSQPHSP
                     RVHSLFTEGTLDPQAPDPCLMARETQNQDAPCPAPFMAEEASSPSTGQPSLCSFEINE
                     IYSGCLILEDDIEEPPGAASSLEADGPNQVDELKSMEEELDKMEREACCFGSEDESSS
                     KAETEYSFDDWDWQNGSLSSLSLPESTREAKSNLNNMSTTEEYLISKCVLDLKIMQTI
                     MHENDDRLRNIEQILDEVEMKQKEQEERMSLWATSREFTNAYKLPLAVGPPSLNYIPP
                     VLQLSGGQKPDTSGNYPTLPRFPRMLPTLCDPGKQNTDEQFQCTQGAKDSLETSRIQN
                     TSSQGRPRESTAQAKATQFNSALFTLSSHRQGPSASPSCHWDSTRMSVEPVSSEIYNA
                     ESRNKDDGKVHLKWKMEVKEMAKKAATGQLTVPPWHPQSSLTLESEAENEPDALLQPP
                     IRSPENTDWQRVIEYHRENDEPRGNGKFDKTGNNDCDSDQHGRQPRLGSFTSIRHPSP
                     RQKEQPEHSEAFQASSDTLVAVEKSYSTSSPIEEDFEGIQGAFAQPQVSGEEKFQMRK
                     ILGKNAEILPRSQFQPVRSTEDEQEETSKESPKELKEKDISLTDIQDLSSISYEPDSS
                     FKEASCKTPKINHAPTSVSTPLSPGSVSSAASQYKDCLESITFQVKTEFASCWNSQEF
                     IQTLSDDFISVRERAKKLDSLLTSSETPPSRLTGLKRLSSFIGAGSPSLVKACDSSPP
                     HATQRRSLPKVEAFSQHHIDELPPPSQELLDDIELLKQQQGSSTVLHENTASDGGGTA
                     NDQRHLEEQETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEESVELQ
                     DLPKGSERETNIKDQKVGEEKRKREDSITPERRKSEGVLGTSEEDELKSCFWKRLGWS
                     ESSRIIVLDQSDLSD"
     exon            245..359
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            360..525
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            526..662
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            663..744
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            745..875
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            876..989
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1113
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1292
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1444
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1635
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..1786
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..2577
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            2578..2684
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            2685..2810
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            2811..2896
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            2897..3178
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3179..3279
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3280..3346
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3347..3428
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3429..3491
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3492..3619
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3620..3825
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3826..3925
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3926..3994
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            3995..4072
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            4073..4172
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            4173..4265
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            4266..4375
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            4376..4427
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     exon            4428..4797
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4771..4776
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /note="hexamer: AATAAA"
     polyA_site      4797
                     /gene="TEX14"
                     /gene_synonym="CT113; SgK307; SPGF23"
                     /note="major polyA site"
ORIGIN      
        1 attccccgca cccacccacg tcttcccggg agtcgtatcc cgagcatgga ggttactgag
       61 accgttattt cttcatggcc tgcctagctt aagcagtagc tggaaaagat gtctcgggct
      121 gttcgtcttc cagtcccctg tcctgttcaa cttggtacct taagaaatga ctccctggaa
      181 gctcagcttc atgagtatgt caaacaaggg aactatgtga aagtgaagaa aattcttaag
      241 aaaggaattt atgttgatgc agttaactcc ttgggccaaa cagcactttt tgttgcggcg
      301 ttattgggcc ttaggaaatt cgttgatgtt ctggtggatt atggatcaga tccaaatcac
      361 cgctgctttg atgggagcac ccctgtccat gcagcagcat tttcgggcaa tcagtggatc
      421 cttagcaaac tgctggatgc aggaggtgac ctgcgactcc acgatgagag gggtcaaaac
      481 ccgaagactt gggctttgac agcaggaaag gagcgtagca cccagatagt ggagttcatg
      541 cagcgctgtg cctcacacat gcaggccatc atccagggct tctcttacga cctcctgaag
      601 aagatagact ccccgcagcg gcttgtctac agcccgtcct ggtgtggggg cctcgtgcag
      661 ggaaacccta atggctctcc taaccgactg cttaaagctg gagtcatttc tgctcaaaat
      721 atctacagct ttggttttgg gaagttttat cttactgggg cgacacagat ggcctatcta
      781 ggatctcttc cggtcattgg agaaaaggaa gtgattcaag ctgatgatga gcccaccttc
      841 tctttcttca gcggccccta catggtcatg accaacctag tgtggaatgg gagcagggtc
      901 acagtgaaag agctgaatct ccccacccac ccacactgca gcaggctgcg gctggccgac
      961 ttgttaattg ccgagcagga acacagcagc aagctgcggc acccctactt gctacagttg
     1021 atggctgtgt gtctctccca ggacctagag aaaacccgcc ttgtgtacga gcgcatcact
     1081 atcggcacat tgttcagtgt ccttcatgaa cgacggtccc agttcccagt gctgcacatg
     1141 gaggtgattg tgcacctgct gctccagata tctgatgccc tgagatacct gcatttccag
     1201 gggtttatcc accgctccct cagctcctat gctgtccata tcatctcccc aggtgaagcg
     1261 aggctgacca acctggagta catgttggaa agcgaggaca gaggtgtaca gagggacctg
     1321 actcgagtgc cccttcctac gcagctatac aactgggccg caccagaagt gatcttacag
     1381 aaggcagcca cagtgaaatc agacatctac agcttttcta tgatcatgca ggagatttta
     1441 acagatgaca taccctggaa gggcttagat ggctcagttg ttaaaaaagc cgtagtctcg
     1501 gggaattatt tagaagctga tgtcaggctt ccgaaacctt actatgatat tgttaagtca
     1561 ggcatccacg tcaagcagaa agaccgaact atgaaccttc aagatatccg gtatattctg
     1621 aagaatgact taaaggattt tactggagcc cagagaactc aaccaaccga gagccccaga
     1681 gtgcagagat acggactcca tcccgatgtc aatgtctatc taggactgac ttcagaacac
     1741 cccagagaga cacctgacat ggaaatcata gaactaaagg aaatgggcag tcaacctcat
     1801 tcaccaaggg ttcactcttt attcactgag gggacactag atcctcaggc cccagatcca
     1861 tgtctgatgg ccagggagac tcagaatcaa gatgctcctt gccctgctcc atttatggca
     1921 gaagaggcca gcagccccag cacaggtcag ccaagcctct gcagtttcga aatcaacgag
     1981 atctactcag gctgcttgat tttggaagat gacatagaag agcctccagg agctgcttca
     2041 tctttggagg cagacggacc taaccaggta gatgaactga aatccatgga agaagagctg
     2101 gataagatgg agagagaggc gtgttgtttt ggcagtgagg atgagagctc ttcaaaagct
     2161 gagacagagt actcttttga tgactgggac tggcaaaacg gttcactcag ttcactcagc
     2221 cttcctgagt caaccagaga agccaagagc aatttgaaca acatgtccac gactgaggag
     2281 tatctcatca gtaagtgtgt gctggatcta aagattatgc agacaataat gcacgagaat
     2341 gatgataggc tgaggaatat cgagcagata ttagatgaag tcgagatgaa acagaaggaa
     2401 caggaagagc gcatgtcttt atgggccact tcaagagagt ttacaaatgc ctacaagtta
     2461 cctctggccg tgggccctcc atctttaaac tatattcctc ctgtcctaca gctttcaggg
     2521 ggtcagaagc cagacaccag tggcaactac ccaaccctac caagatttcc aagaatgctg
     2581 ccgactcttt gtgaccctgg aaaacagaac acagatgaac aatttcagtg cactcaagga
     2641 gccaaggaca gtttggaaac aagcaggatc caaaatacca gtagccaggg aagacctaga
     2701 gagtccactg cccaagccaa agccacacag tttaatagtg cactcttcac tctgtcaagc
     2761 caccggcagg gaccttctgc atcacccagc tgtcactggg actctaccag gatgagtgtg
     2821 gaacctgttt cttctgaaat ctataatgca gagtccagaa ataaagatga tggaaaggta
     2881 cacttaaaat ggaaaatgga ggtgaaagaa atggcaaaga aagcagctac tggacagctc
     2941 acagtacctc cttggcatcc tcagagtagt ctgactttag agagcgaggc tgaaaatgag
     3001 cccgacgccc tgctgcagcc ccccattagg agcccagaaa acacggattg gcagcgagtt
     3061 attgagtatc atagggaaaa tgatgagccc agaggaaatg gcaagtttga caagacgggc
     3121 aacaatgact gtgacagtga ccagcatggc agacagccca ggcttggaag cttcaccagt
     3181 atcaggcacc catctcccag acaaaaggag caaccagagc atagtgaagc cttccaagca
     3241 agttctgaca cattggtggc tgtagagaaa tcttacagta cctcgagtcc catagaagag
     3301 gactttgaag gaatacaagg tgcatttgcc caacctcaag tctctggtga ggaaaagttc
     3361 caaatgagaa aaattcttgg aaagaatgct gagattttgc ccaggtctca atttcaacct
     3421 gtacgaagta ctgaagatga acaagaagag acatcaaagg agtcaccaaa ggaactgaaa
     3481 gagaaagaca tatcattgac ggatattcaa gacctgtcta gtatctccta tgaaccagac
     3541 agctctttta aggaagcttc atgcaaaaca cccaaaataa accatgcacc taccagtgtc
     3601 agcactccac tcagcccagg gtccgtttct tcagctgcca gtcagtataa agactgcctt
     3661 gaaagtatca catttcaggt taagacagag tttgcctctt gctggaacag tcaagaattt
     3721 attcaaactt tgtctgatga ctttataagt gtccgagaga gagcaaagaa actggattct
     3781 ctccttactt cctctgaaac tcccccttca agactgactg gtcttaaaag attgtcttca
     3841 tttattgggg ctggatcccc cagccttgtt aaggcatgtg actcatcacc accccatgcc
     3901 acccagagaa ggagcctgcc taaagtagaa gccttctcac agcatcacat tgatgagctg
     3961 ccaccaccat ctcaggagct acttgatgac attgagctct tgaaacagca gcagggctca
     4021 tccacggtgt tgcatgagaa cacagcaagt gatggaggag gcactgcaaa tgatcaaagg
     4081 cacttagaag aacaagaaac tgacagtaaa aaagaagata gtagtatgct tttgtccaaa
     4141 gaaactgaag atcttggaga ggacacagag agagctcact ctactctgga tgaggacctg
     4201 gaaagatggc tgcagccacc tgaggagagc gtggagctac aagaccttcc caagggctct
     4261 gaaagggaga caaatatcaa agatcaaaaa gttggtgaag agaaaagaaa aagggaagat
     4321 agcattacac cagaaagaag gaaatcagag ggtgttctag ggacttctga agaagatgaa
     4381 ctaaaatcct gtttttggaa gcgactaggt tggtccgaat catccaggat aatcgtgctg
     4441 gatcagagtg acttgtcaga ctgattggaa ttggatcata gacggactcc tggcctgagt
     4501 ttgagtgtcc tggttgtaag ctcctttctt ctctttctgc ttcagttgct gtcagggcag
     4561 cagttccagt tctgtaagtc tcactttgtt cagctgccac aatagacatc atcgtttggc
     4621 cctctctgtt agcagcacat tcaaccattt gttttcagtc agatttctga aaagtgagag
     4681 gtagttttga tagtaaaaat ttttggttgt gcctagaatg gctttggttt tgttgatgtt
     4741 aattttcaaa aactttaact cttgttatat aataaaatgt ttaattttaa taacaga
//
