LOCUS       NM_007110              10775 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens telomerase associated protein 1 (TEP1), transcript
            variant 1, mRNA.
ACCESSION   NM_007110
VERSION     NM_007110.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10775)
  AUTHORS   Wang,Y., Xu,Y., Li,H., Tang,T., Qiao,Y., Cheng,Y., Zhang,L.,
            Song,J., Su,Y., Zhang,X., Wang,J., Shang,Q., Song,L., Gao,C.,
            Zhu,D., Wang,X., Zhu,C. and Xing,Q.
  TITLE     TEP1 is a risk gene for sporadic cerebral palsy
  JOURNAL   J Genet Genomics 48 (12), 1134-1138 (2021)
   PUBMED   34543729
  REMARK    GeneRIF: TEP1 is a risk gene for sporadic cerebral palsy.
REFERENCE   2  (bases 1 to 10775)
  AUTHORS   Pietras,P., Lesniczak-Staszak,M., Kasprzak,A., Andrzejewska,M.,
            Jopek,K., Sowinski,M., Rucinski,M., Lyons,S.M., Ivanov,P. and
            Szaflarski,W.
  TITLE     MVP Expression Facilitates Tumor Cell Proliferation and Migration
            Supporting the Metastasis of Colorectal Cancer Cells
  JOURNAL   Int J Mol Sci 22 (22), 12121 (2021)
   PUBMED   34829999
  REMARK    GeneRIF: MVP Expression Facilitates Tumor Cell Proliferation and
            Migration Supporting the Metastasis of Colorectal Cancer Cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 10775)
  AUTHORS   Li,S., Song,F., Lei,X., Li,J., Li,F. and Tan,H.
  TITLE     hsa_circ_0004018 suppresses the progression of liver fibrosis
            through regulating the hsa-miR-660-3p/TEP1 axis
  JOURNAL   Aging (Albany NY) 12 (12), 11517-11529 (2020)
   PUBMED   32584784
  REMARK    GeneRIF: hsa_circ_0004018 suppresses the progression of liver
            fibrosis through regulating the hsa-miR-660-3p/TEP1 axis.
            Erratum:[Aging (Albany NY). 2021 Jun 15;13(11):15690. doi:
            10.18632/aging.203218.. PMID: 34129523]
REFERENCE   4  (bases 1 to 10775)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 10775)
  AUTHORS   Jin,D.H., Kim,S., Kim,D.H. and Park,J.
  TITLE     Two genetic variants in telomerase-associated protein 1 are
            associated with stomach cancer risk
  JOURNAL   J Hum Genet 61 (10), 885-889 (2016)
   PUBMED   27305982
  REMARK    GeneRIF: The current results suggested that genetic variants at
            TEP1 SNPs rs1760893 and rs1713423 may be associated significantly
            with increased risk of stomach cancer.
REFERENCE   6  (bases 1 to 10775)
  AUTHORS   Li,H., Zhao,L., Yang,Z., Funder,J.W. and Liu,J.P.
  TITLE     Telomerase is controlled by protein kinase Calpha in human breast
            cancer cells
  JOURNAL   J Biol Chem 273 (50), 33436-33442 (1998)
   PUBMED   9837921
REFERENCE   7  (bases 1 to 10775)
  AUTHORS   Harrington,L., Zhou,W., McPhail,T., Oulton,R., Yeung,D.S., Mar,V.,
            Bass,M.B. and Robinson,M.O.
  TITLE     Human telomerase contains evolutionarily conserved catalytic and
            structural subunits
  JOURNAL   Genes Dev 11 (23), 3109-3115 (1997)
   PUBMED   9389643
REFERENCE   8  (bases 1 to 10775)
  AUTHORS   Saito,T., Matsuda,Y., Suzuki,T., Hayashi,A., Yuan,X., Saito,M.,
            Nakayama,J., Hori,T. and Ishikawa,F.
  TITLE     Comparative gene mapping of the human and mouse TEP1 genes, which
            encode one protein component of telomerases
  JOURNAL   Genomics 46 (1), 46-50 (1997)
   PUBMED   9403057
REFERENCE   9  (bases 1 to 10775)
  AUTHORS   Harrington,L., McPhail,T., Mar,V., Zhou,W., Oulton,R., Bass,M.B.,
            Arruda,I. and Robinson,M.O.
  TITLE     A mammalian telomerase-associated protein
  JOURNAL   Science 275 (5302), 973-977 (1997)
   PUBMED   9020079
REFERENCE   10 (bases 1 to 10775)
  AUTHORS   Joly,E.C., Tremblay,E., Tanguay,R.M., Wu,Y. and Bibor-Hardy,V.
  TITLE     TRiC-P5, a novel TCP1-related protein, is localized in the
            cytoplasm and in the nuclear matrix
  JOURNAL   J Cell Sci 107 (Pt 10), 2851-2859 (1994)
   PUBMED   7876352
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL355075.6, BC126107.1 and
            BC143815.1.
            
            On Nov 22, 2018 this sequence version replaced NM_007110.4.
            
            Summary: This gene product is a component of the ribonucleoprotein
            complex responsible for telomerase activity which catalyzes the
            addition of new telomeres on the chromosome ends. The
            telomerase-associated proteins are conserved from ciliates to
            humans. Alternative splicing results in multiple transcript
            variants. [provided by RefSeq, Jan 2016].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U86136.2, BC126107.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000262715.10/ ENSP00000262715.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                AL355075.6         106464-106544
            82-2268             BC126107.1         1-2187
            2269-2853           BC143815.1         1864-2448
            2854-2854           AL355075.6         133390-133390
            2855-8048           BC126107.1         2774-7967
            8049-10775          AL355075.6         151572-154298
FEATURES             Location/Qualifiers
     source          1..10775
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..10775
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /note="telomerase associated protein 1"
                     /db_xref="GeneID:7011"
                     /db_xref="HGNC:HGNC:11726"
                     /db_xref="MIM:601686"
     exon            1..97
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            98..688
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..8005
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /note="isoform 1 is encoded by transcript variant 1; TROVE
                     domain family, member 1; p80 telomerase homolog;
                     telomerase protein component 1; telomerase protein 1"
                     /codon_start=1
                     /product="telomerase protein component 1 isoform 1"
                     /protein_id="NP_009041.2"
                     /db_xref="CCDS:CCDS9548.1"
                     /db_xref="GeneID:7011"
                     /db_xref="HGNC:HGNC:11726"
                     /db_xref="MIM:601686"
                     /translation="MEKLHGHVSAHPDILSLENRCLAMLPDLQPLEKLHQHVSTHSDI
                     LSLKNQCLATLPDLKTMEKPHGYVSAHPDILSLENQCLATLSDLKTMEKPHGHVSAHP
                     DILSLENRCLATLSSLKSTVSASPLFQSLQISHMTQADLYRVNNSNCLLSEPPSWRAQ
                     HFSKGLDLSTCPIALKSISATETAQEATLGRWFDSEEKKGAETQMPSYSLSLGEEEEV
                     EDLAVKLTSGDSESHPEPTDHVLQEKKMALLSLLCSTLVSEVNMNNTSDPTLAAIFEI
                     CRELALLEPEFILKASLYARQQLNVRNVANNILAIAAFLPACRPHLRRYFCAIVQLPS
                     DWIQVAELYQSLAEGDKNKLVPLPACLRTAMTDKFAQFDEYQLAKYNPRKHRAKRHPR
                     RPPRSPGMEPPFSHRCFPRYIGFLREEQRKFEKAGDTVSEKKNPPRFTLKKLVQRLHI
                     HKPAQHVQALLGYRYPSNLQLFSRSRLPGPWDSSRAGKRMKLSRPETWERELSLRGNK
                     ASVWEELIENGKLPFMAMLRNLCNLLRVGISSRHHELILQRLQHAKSVIHSRQFPFRF
                     LNAHDAIDALEAQLRNQALPFPSNITLMRRILTRNEKNRPRRRFLCHLSRQQLRMAMR
                     IPVLYEQLKREKLRVHKARQWKYDGEMLNRYRQALETAVNLSVKHSLPLLPGRTVLVY
                     LTDANADRLCPKSNPQGPPLNYALLLIGMMITRAEQVDVVLCGGDTLKTAVLKAEEGI
                     LKTAIKLQAQVQEFDENDGWSLNTFGKYLLSLAGQRVPVDRVILLGQSMDDGMINVAK
                     QLYWQRVNSKCLFVGILLRRVQYLSTDLNPNDVTLSGCTDAILKFIAEHGASHLLEHV
                     GQMDKIFKIPPPPGKTGVQSLRPLEEDTPSPLAPVSQQGWRSIRLFISSTFRDMHGER
                     DLLLRSVLPALQARAAPHRISLHGIDLRWGVTEEETRRNRQLEVCLGEVENAQLFVGI
                     LGSRYGYIPPSYNLPDHPHFHWAQQYPSGRSVTEMEVMQFLNRNQRLQPSAQALIYFR
                     DSSFLSSVPDAWKSDFVSESEEAARRISELKSYLSRQKGITCRRYPCEWGGVAAGRPY
                     VGGLEEFGQLVLQDVWNMIQKLYLQPGALLEQPVSIPDDDLVQATFQQLQKPPSPARP
                     RLLQDTVQRLMLPHGRLSLVTGQSGQGKTAFLASLVSALQAPDGAKVASLVFFHFSGA
                     RPDQGLALTLLRRLCTYLRGQLKEPGALPSTYRSLVWELQQRLLPKSAESLHPGQTQV
                     LIIDGADRLVDQNGQLISDWIPKKLPRCVHLVLSVSSDAGLGETLEQSQGAHVLALGP
                     LEASARARLVREELALYGKRLEESPFNNQMRLLLVKRESGRPLYLRLVTDHLRLFTLY
                     EQVSERLRTLPATVPLLLQHILSTLEKEHGPDVLPQALTALEVTRSGLTVDQLHGVLS
                     VWRTLPKGTKSWEEAVAAGNSGDPYPMGPFACLVQSLRSLLGEGPLERPGARLCLPDG
                     PLRTAAKRCYGKRPGLEDTAHILIAAQLWKTCDADASGTFRSCPPEALGDLPYHLLQS
                     GNRGLLSKFLTNLHVVAAHLELGLVSRLLEAHALYASSVPKEEQKLPEADVAVFRTFL
                     RQQASILSQYPRLLPQQAANQPLDSPLCHQASLLSRRWHLQHTLRWLNKPRTMKNQQS
                     SSLSLAVSSSPTAVAFSTNGQRAAVGTANGTVYLLDLRTWQEEKSVVSGCDGISACLF
                     LSDDTLFLTAFDGLLELWDLQHGCRVLQTKAHQYQITGCCLSPDCRLLATVCLGGCLK
                     LWDTVRGQLAFQHTYPKSLNCVAFHPEGQVIATGSWAGSISFFQVDGLKVTKDLGAPG
                     ASIRTLAFNVPGGVVAVGRLDSMVELWAWREGARLAAFPAHHGFVAAALFLHAGCQLL
                     TAGEDGKVQVWSGSLGRPRGHLGSLSLSPALSVALSPDGDRVAVGYRADGIRIYKISS
                     GSQGAQGQALDVAVSALAWLSPKVLVSGAEDGSLQGWALKECSLQSLWLLSRFQKPVL
                     GLATSQELLASASEDFTVQLWPRQLLTRPHKAEDFPCGTELRGHEGPVSCCSFSTDGG
                     SLATGGRDRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWTKDNLLISCSSDGSVGL
                     WDPESGQRLGQFLGHQSAVSAVAAVEEHVVSVSRDGTLKVWDHQGVELTSIPAHSGPI
                     SHCAAAMEPRAAGQPGSELLVVTVGLDGATRLWHPLLVCQTHTLLGHSGPVRAAAVSE
                     TSGLMLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWAPDGSMAVSGNQAGELIL
                     WQEAKAVATAQAPGHIGALIWSSAHTFFVLSADEKISEWQVKLRKGSAPGNLSLHLNR
                     ILQEDLGVLTSLDWAPDGHFLILAKADLKLLCMKPGDAPSEIWSSYTENPMILSTHKE
                     YGIFVLQPKDPGVLSFLRQKESGEFEERLNFDINLENPSRTLISITQAKPESESSFLC
                     ASSDGILWNLAKCSPEGEWTTGNMWQKKANTPETQTPGTDPSTCRESDASMDSDASMD
                     SEPTPHLKTRQRRKIHSGSVTALHVLPELLVTASKDRDVKLWERPSMQLLGLFRCEGS
                     VSCLEPWLGANSTLQLAVGDVQGNVYFLNWE"
     exon            689..856
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            857..991
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1153
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1315
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1316..1387
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1388..1512
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1670
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1671..1780
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1781..1871
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..2049
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2218
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2377
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            2378..2455
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            2456..2586
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            2587..2646
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            2647..2805
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            2806..2982
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            2983..3103
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            3104..3228
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            3229..3342
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            3343..3460
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            3461..3655
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            3656..3831
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            3832..3988
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            3989..4168
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            4169..4261
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            4262..4394
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            4395..4545
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            4546..4679
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            4680..4768
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            4769..4883
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            4884..5124
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            5125..5248
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            5249..5373
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            5374..5473
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            5474..5629
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            5630..5842
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            5843..5996
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            5997..6209
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            6210..6370
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            6371..6484
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            6485..6592
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            6593..6725
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            6726..6802
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            6803..6935
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            6936..7072
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            7073..7197
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            7198..7341
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            7342..7438
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            7439..7544
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            7545..7777
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            7778..7882
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     exon            7883..10775
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10756..10761
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /note="hexamer: AATAAA"
     polyA_site      10775
                     /gene="TEP1"
                     /gene_synonym="p240; TLP1; TP1; TROVE1; VAULT2"
                     /note="major polyA site"
ORIGIN      
        1 agatccgcat ccggctcctc ccccggctgc cacccttccc accggcagaa tccagagcga
       61 agtttctgct tcctgctgcg ggaatcggac gccccaggca tatacaagct gagtttcagc
      121 catggaaaaa ctccatgggc atgtgtctgc ccatccagac atcctctcct tggagaaccg
      181 gtgcctggct atgctccctg acttacagcc cttggagaaa ctacatcagc atgtatctac
      241 ccactcagat atcctctcct tgaagaacca gtgcctagcc acgcttcctg acctgaagac
      301 catggaaaaa ccacatggat atgtgtctgc ccacccagac atcctctcct tggagaacca
      361 gtgcctggcc acactttctg acctgaagac catggagaaa ccacatggac atgtttctgc
      421 ccacccagac atcctctcct tggagaaccg gtgcctggcc accctctcta gtctaaagag
      481 cactgtgtct gccagcccct tgttccagag tctacagata tctcacatga cgcaagctga
      541 tttgtaccgt gtgaacaaca gcaattgcct gctctctgag cctccaagtt ggagggctca
      601 gcatttctct aagggactag acctttcaac ctgccctata gccctgaaat ccatctctgc
      661 cacagagaca gctcaggaag caactttggg tcgttggttt gattcagaag agaagaaagg
      721 ggcagagacc caaatgcctt cttatagtct gagcttggga gaggaggagg aggtggagga
      781 tctggccgtg aagctcacct ctggagactc tgaatctcat ccagagccta ctgaccatgt
      841 ccttcaggaa aagaagatgg ctctactgag cttgctgtgc tctactctgg tctcagaagt
      901 aaacatgaac aatacatctg accccaccct ggctgccatt tttgaaatct gtcgtgaact
      961 tgccctcctg gagcctgagt ttatcctcaa ggcatctttg tatgccaggc agcagctgaa
     1021 cgtccggaat gtggccaata acatcttggc cattgctgct ttcttgccgg cgtgtcgccc
     1081 ccacctgcga cgatatttct gtgccattgt ccagctgcct tctgactgga tccaggtggc
     1141 tgagctttac cagagcctgg ctgagggaga taagaataag ctggtgcccc tgcccgcctg
     1201 tctccgtact gccatgacgg acaaatttgc ccagtttgac gagtaccagc tggctaagta
     1261 caaccctcgg aagcaccggg ccaagagaca cccccgccgg ccaccccgct ctccagggat
     1321 ggagcctcca ttttctcaca gatgttttcc aaggtacata gggtttctca gagaagagca
     1381 gagaaagttt gagaaggccg gtgatacagt gtcagagaaa aagaatcctc caaggttcac
     1441 cctgaagaag ctggttcagc gactgcacat ccacaagcct gcccagcacg ttcaagccct
     1501 gctgggttac agatacccct ccaacctaca gctcttttct cgaagtcgcc ttcctgggcc
     1561 ttgggattct agcagagctg ggaagaggat gaagctgtct aggccagaga cctgggagcg
     1621 ggagctgagc ctacggggga acaaagcgtc ggtctgggag gaactcattg aaaatgggaa
     1681 gcttcccttc atggccatgc ttcggaacct gtgcaacctg ctgcgggttg gaatcagttc
     1741 ccgccaccat gagctcattc tccagagact ccagcatgcg aagtcggtga tccacagtcg
     1801 gcagtttcca ttcagatttc ttaacgccca tgatgccatt gatgccctcg aggctcaact
     1861 cagaaatcaa gcattgccct ttccttcgaa tataacactg atgaggcgga tactaactag
     1921 aaatgaaaag aaccgtccca ggcggaggtt tctttgccac ctaagccgtc agcagcttcg
     1981 gatggcaatg aggatacctg tgttgtatga gcagctcaag agggagaagc tgagagtaca
     2041 caaggccaga cagtggaaat atgatggtga gatgctgaac aggtaccgac aggccctaga
     2101 gacagctgtg aacctctctg tgaagcacag cctgcccctg ctgccaggcc gcactgtctt
     2161 ggtctatctg acagatgcta atgcagacag gctctgtcca aagagcaacc cacaagggcc
     2221 cccgctgaac tatgcactgc tgttgattgg gatgatgatc acgagggcgg agcaggtgga
     2281 cgtcgtgctg tgtggaggtg acactctgaa gactgcagtg cttaaggcag aagaaggcat
     2341 cctgaagact gccatcaagc tccaggctca agtccaggag tttgatgaaa atgatggatg
     2401 gtccctgaat acttttggga aatacctgct gtctctggct ggccaaaggg ttcctgtgga
     2461 cagggtcatc ctccttggcc aaagcatgga tgatggaatg ataaatgtgg ccaaacagct
     2521 ttactggcag cgtgtgaatt ccaagtgcct ctttgttggt atcctcctaa gaagggtaca
     2581 atacctgtca acagatttga atcccaatga tgtgacactc tcaggctgta ctgatgcgat
     2641 actgaagttc attgcagagc atggggcctc ccatcttctg gaacatgtgg gccaaatgga
     2701 caaaatattc aagattccac cacccccagg aaagacaggg gtccagtctc tccggccact
     2761 ggaagaggac actccaagcc ccttggctcc tgtttcccag caaggatggc gcagcatccg
     2821 gcttttcatt tcatccactt tccgagacat gcatggggag cgggacctgc tgctgaggtc
     2881 tgtgctgcca gcactgcagg cccgagcggc ccctcaccgt atcagccttc acggaatcga
     2941 cctccgctgg ggcgtcactg aggaggagac ccgtaggaac agacaactgg aagtgtgcct
     3001 tggggaggtg gagaacgcac agctgtttgt ggggattctg ggctcccgtt atggatacat
     3061 tccccccagc tacaaccttc ctgaccatcc acacttccac tgggcccagc agtacccttc
     3121 agggcgctct gtgacagaga tggaggtgat gcagttcctg aaccggaacc aacgtctgca
     3181 gccctctgcc caagctctca tctacttccg ggattccagc ttcctcagct ctgtgccaga
     3241 tgcctggaaa tctgactttg tttctgagtc tgaagaggcc gcacgtcgga tctcagaact
     3301 gaagagctac ctaagcagac agaaagggat cacctgccgc agatacccct gtgagtgggg
     3361 gggtgtggca gctggccggc cctatgttgg cgggctggag gagtttgggc agttggttct
     3421 gcaggatgta tggaatatga tccagaagct ctacctgcag cctggggccc tgctggagca
     3481 gccagtgtcc atcccagacg atgacttggt ccaggccacc ttccagcagc tgcagaagcc
     3541 accgagtcct gcccggccac gccttcttca ggacacagtg caacggctga tgctgcccca
     3601 cggaaggctg agcctggtga cggggcagtc aggacagggc aagacagcct tcctggcatc
     3661 tcttgtgtca gccctgcagg ctcctgatgg ggccaaggtg gcatcattag tcttcttcca
     3721 cttttctggg gctcgtcctg accagggtct tgccctcact ctgctcagac gcctctgtac
     3781 ctatctgcgt ggccaactaa aagagccagg tgccctcccc agcacctacc gaagcctggt
     3841 gtgggagctg cagcagaggc tgctgcccaa gtctgctgag tccctgcatc ctggccagac
     3901 ccaggtcctg atcatcgatg gggctgatag gttagtggac cagaatgggc agctgatttc
     3961 agactggatc ccaaagaagc ttccccggtg tgtacacctg gtgctgagtg tgtctagtga
     4021 tgcaggccta ggggagaccc ttgagcagag ccagggtgcc cacgtgctgg ccttggggcc
     4081 tctggaggcc tctgctcggg cccggctggt gagagaggag ctggccctgt acgggaagcg
     4141 gctggaggag tcaccattta acaaccagat gcgactgctg ctggtgaagc gggaatcagg
     4201 ccggccgctc tacctgcgct tggtcaccga tcacctgagg ctcttcacgc tgtatgagca
     4261 ggtgtctgag agactccgga ccctgcctgc cactgtcccc ctgctgctgc agcacatcct
     4321 gagcacactg gagaaggagc acgggcctga tgtccttccc caggccttga ctgccctaga
     4381 agtcacacgg agtggtttga ctgtggacca gctgcacgga gtgctgagtg tgtggcggac
     4441 actaccgaag gggactaaga gctgggaaga agcagtggct gctggtaaca gtggagaccc
     4501 ctaccccatg ggcccgtttg cctgcctcgt ccagagtctg cgcagtttgc taggggaggg
     4561 ccctctggag cgccctggtg cccggctgtg cctccctgat gggcccctga gaacagcagc
     4621 taaacgttgc tatgggaaga ggccagggct agaggacacg gcacacatcc tcattgcagc
     4681 tcagctctgg aagacatgtg acgctgatgc ctcaggcacc ttccgaagtt gccctcctga
     4741 ggctctggga gacctgcctt accacctgct ccagagcggg aaccgtggac ttctttcgaa
     4801 gttccttacc aacctccatg tggtggctgc acacttggaa ttgggtctgg tctctcggct
     4861 cttggaggcc catgccctct atgcttcttc agtccccaaa gaggaacaaa agctccccga
     4921 ggctgacgtt gcagtgtttc gcaccttcct gaggcagcag gcttcaatcc tcagccagta
     4981 cccccggctc ctgccccagc aggcagccaa ccagcccctg gactcacctc tttgccacca
     5041 agcctcgctg ctctcccgga gatggcacct ccaacacaca ctacgatggc ttaataaacc
     5101 ccggaccatg aaaaatcagc aaagctccag cctgtctctg gcagtttcct catcccctac
     5161 tgctgtggcc ttctccacca atgggcaaag agcagctgtg ggcactgcca atgggacagt
     5221 ttacctgttg gacctgagaa cttggcagga ggagaagtct gtggtgagtg gctgtgatgg
     5281 aatctctgct tgtttgttcc tctccgatga tacactcttt cttactgcct tcgacgggct
     5341 cctggagctc tgggacctgc agcatggttg tcgggtgctg cagactaagg ctcaccagta
     5401 ccaaatcact ggctgctgcc tgagcccaga ctgccggctg ctagccaccg tgtgcttggg
     5461 aggatgccta aagctgtggg acacagtccg tgggcagctg gccttccagc acacctaccc
     5521 caagtccctg aactgtgttg ccttccaccc agaggggcag gtaatagcca caggcagctg
     5581 ggctggcagc atcagcttct tccaggtgga tgggctcaaa gtcaccaagg acctgggggc
     5641 acccggagcc tctatccgta ccttggcctt caatgtgcct gggggggttg tggctgtggg
     5701 ccggctggac agtatggtgg agctgtgggc ctggcgagaa ggggcacggc tggctgcctt
     5761 ccctgcccac catggctttg ttgctgctgc gcttttcctg catgcgggtt gccagttact
     5821 gacggctgga gaggatggca aggttcaggt gtggtcaggg tctctgggtc ggccccgtgg
     5881 gcacctgggt tccctttctc tctctcctgc cctctctgtg gcactcagcc cagatggtga
     5941 tcgggtggct gttggatatc gagcggatgg cattaggatc tacaaaatct cttcaggttc
     6001 ccagggggct cagggtcagg cactggatgt ggcagtgtcc gccctggcct ggctaagccc
     6061 caaggtattg gtgagtggtg cagaagatgg gtccttgcag ggctgggcac tcaaggaatg
     6121 ctcccttcag tccctctggc tcctgtccag attccagaag cctgtgctag gactggccac
     6181 ttcccaggag ctcttggctt ctgcctcaga ggatttcaca gtgcagctgt ggccaaggca
     6241 gctgctgacg cggccacaca aggcagaaga ctttccctgt ggcactgagc tgcggggaca
     6301 tgagggccct gtgagctgct gtagtttcag cactgatgga ggcagcctgg ccaccggggg
     6361 ccgggatcgg agtctcctct gctgggacgt gaggacaccc aaaacccctg ttttgatcca
     6421 ctccttccct gcctgtcacc gtgactgggt cactggctgt gcctggacca aagataacct
     6481 actgatatcc tgctccagtg atggctctgt ggggctctgg gacccagagt caggacagcg
     6541 gcttggtcag ttcctgggtc atcagagtgc tgtgagcgct gtggcagctg tggaggagca
     6601 cgtggtgtct gtgagccggg atgggacctt gaaagtgtgg gaccatcaag gcgtggagct
     6661 gaccagcatc cctgctcact caggacccat tagccactgt gcagctgcca tggagccccg
     6721 tgcagctgga cagcctgggt cagagcttct ggtggtaacc gtcgggctag atggggccac
     6781 acggttatgg catccactct tggtgtgcca aacccacacc ctcctgggac acagcggccc
     6841 agtccgtgct gctgctgttt cagaaacctc aggcctcatg ctgaccgcct ctgaggatgg
     6901 ttctgtacgg ctctggcagg ttcctaagga agcagatgac acatgtatac caaggagttc
     6961 tgcagccgtc actgctgtgg cttgggcacc agatggttcc atggcagtat ctggaaatca
     7021 agctggggaa ctaatcttgt ggcaggaagc taaggctgtg gccacagcac aggctccagg
     7081 ccacattggt gctctgatct ggtcctcggc acacaccttt tttgtcctca gtgctgatga
     7141 gaaaatcagc gagtggcaag tgaaactgcg gaagggttcg gcacccggaa atttgagtct
     7201 tcacctgaac cgaattctac aggaggactt aggggtgctg acaagtctgg attgggctcc
     7261 tgatggtcac tttctcatct tggccaaagc agatttgaag ttactttgca tgaagccagg
     7321 ggatgctcca tctgaaatct ggagcagcta tacagaaaat cctatgatat tgtccaccca
     7381 caaggagtat ggcatatttg tcctgcagcc caaggatcct ggagttcttt ctttcttgag
     7441 gcaaaaggaa tcaggagagt ttgaagagag gctgaacttt gatataaact tagagaatcc
     7501 tagtaggacc ctaatatcga taactcaagc caaacctgaa tctgagtcct catttttgtg
     7561 tgccagctct gatgggatcc tatggaacct ggccaaatgc agcccagaag gagaatggac
     7621 cacaggtaac atgtggcaga aaaaagcaaa cactccagaa acccaaactc cagggacaga
     7681 cccatctacc tgcagggaat ctgatgccag catggatagt gatgccagca tggatagtga
     7741 gccaacacca catctaaaga cacggcagcg tagaaagatt cactcgggct ctgtcacagc
     7801 cctccatgtg ctacctgagt tgctggtgac agcttcgaag gacagagatg ttaagctatg
     7861 ggagagaccc agtatgcagc tgctgggcct gttccgatgc gaagggtcag tgagctgcct
     7921 ggaaccttgg ctgggcgcta actccaccct gcagcttgcc gtgggagacg tgcagggcaa
     7981 tgtgtacttt ctgaattggg aatgaagatg tgccactcgg gaataatgat accccttgtg
     8041 ctagagatgc aaagcctgaa gacactggta gcttttaata attataaaat taataatttc
     8101 ttgataatta taaaaatgaa gtgtcaaaaa atctcaagtg taggcctgcc tgtgttctca
     8161 tgtggattta gaacaggagg atattctatg tgtatgtata tgtacattct aatgtgtgtc
     8221 tcttcttatt caacattaat ccttactaga accacaagaa agtgaatgaa atctttagta
     8281 ggtactcttt tgaaactagg ttttagaatt cttgcatcac tcgcgggccc taggacccta
     8341 ggatgccatt cttgccagga ggaggaatga gagtgatgtt ggccaacatt caatttgaac
     8401 agagcatgga agacctttca gttcatcggg aaagaatgag ggagggagaa taagtcagtc
     8461 atgcatcagg gcatttagaa agagctatgt ttctgtcaca gagacagccc ttttctcaga
     8521 actacccaga ggaggccggg catggtggct cacgcttgta atcccagcac tttgggaggc
     8581 cgaggtgggc agatcacgag gtcaggagat caagaccatc ctggctaaca tagtgaaacc
     8641 ctgtctctac taaaaaatac aaaaagttag ccaggtgtgg cggcgggcac ctgtagtccc
     8701 agctacttgg gaggctgagg caggagaatg gcgtgaaccc aggaggcgga gcttgcagtg
     8761 agccgagaca ccactgcact ccagcctggg caacagagcg agactctgtc taaaaaaaaa
     8821 aaaaaagaac tacccagatg agaggtgagg agccaagcca ttgaaagcgg aacaaacctt
     8881 ctggttttcc caacttctga cacgactttc aactttagtc aatatggtaa ttggcattct
     8941 cagaagagat cacgaaagtg tcttactctc tctcaaattg aaattcacaa agattaaaac
     9001 taattgagag gtggcacaat catagccatg aactctgatt ttcttaagta aaaaaccttt
     9061 tttttttttt tttgtttttg agatagagtc tggctctgtc acctaggctg gagtgcaatg
     9121 gtgcaatctc agctcagtgc aacctctgct tcctgggttc aagcgattct cctgccttag
     9181 cctcccgagt agctgggatt acaggtgccc accaccacgc ccagctaatt tttgtatttc
     9241 agtagagacg aagtttcacc atgttggcca ggtgggtctc aaactcctga cctcaggtta
     9301 tctgcacacc tcagcctctt aaagttctgg gattacaggc gtgagccatt gtgcccggcc
     9361 cataaaagaa ctttattata tttctaaaat tcaatcatat ggaagaatct attgagcagg
     9421 ttagcctttg cttaactttc ctcctctgtt actccagcct tagctggggt gttttgtaga
     9481 attttcagag catgggagac agacaactag agcttcctcc tgcccttggc ccatgctttt
     9541 aggagagcaa aaggcaaaag attgaaacca ctgactttag tttcctcagg ccctttcttt
     9601 ctgagggtta aagaagaagg aaatgtcttc tgtggccaag aattcaagga cttgtaggag
     9661 ataagtgaag gctattacag ggattttgtc ctggtttggt aggtttctct tggagaaata
     9721 ccactacacc ctggtctaga aatgagtttt gaagacttgg ggagttaaag ggcactgagt
     9781 tttactctca ctgtaccctg attccaggtt ttacatggag aaataacctg agggacttta
     9841 tttctatcca atgccctggt ttccatcctg accagaggat gatgacatcc gctgataggc
     9901 catgcttctg tcttctctta tgtgcctcat gccaagcctc gaaatatacc ttctggacca
     9961 tcatttccac atctaccttg tgactagaag tcctagttat ggtattttga aatttatgat
    10021 ccataatcct tgccagaaat cctgcagcga actatggcat ggcatcatcc tagtcattga
    10081 tttcaatctt ttgccttttg ctcccctaaa atcttgggcc aattgcagga ggaagctcta
    10141 tttgtctctc ttccatgctc tgaaaattat ataaaagcat cccagctaag gctggagtga
    10201 aggggttggg gaaagttaag caaaggctaa cttgaccaat aggctcaata gattcagtct
    10261 tgttggccag gcccacttga agggtttttt gtttcatctt ggagaaggac agtgaggtca
    10321 tggtataatt gttatgagta aagtcaagaa cagcttctag gtaaaagtaa ttatgtaccc
    10381 aaaaggagtt gaagggaaaa tcaatttagg tttacattaa acatccttca agttcttatc
    10441 tttaaatgga gtttcagtgt ctcccaaagg ctggatgagt tttacagtta taaccactgg
    10501 attgtgagac cataggacat ttgaacaatc ttttcttcta cccatctaga aaagcatctt
    10561 ttttatatac caaattttta cacatatatc cacatctgtt tttgaaatct agagcagagg
    10621 tactcaaagt ttggttcatg gactagtgcc agttcacaaa ttgttaatgt tttataatga
    10681 gataagtacg gaagttgaga gtaaccattt agaaactgtg taggaattta aaaagtaata
    10741 tctgacaaat ttaataataa aaatggaggc ttgta
//
