LOCUS       NM_001135580             654 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens tektin bundle interacting protein 1 (TEKTIP1), mRNA.
ACCESSION   NM_001135580 XM_001722762 XM_001726154 XM_001726177
VERSION     NM_001135580.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 654)
  AUTHORS   Gui,M., Farley,H., Anujan,P., Anderson,J.R., Maxwell,D.W.,
            Whitchurch,J.B., Botsch,J.J., Qiu,T., Meleppattu,S., Singh,S.K.,
            Zhang,Q., Thompson,J., Lucas,J.S., Bingle,C.D., Norris,D.P., Roy,S.
            and Brown,A.
  TITLE     De novo identification of mammalian ciliary motility proteins using
            cryo-EM
  JOURNAL   Cell 184 (23), 5791-5806 (2021)
   PUBMED   34715025
REFERENCE   2  (bases 1 to 654)
  AUTHORS   Grimwood,J., Gordon,L.A., Olsen,A., Terry,A., Schmutz,J.,
            Lamerdin,J., Hellsten,U., Goodstein,D., Couronne,O.,
            Tran-Gyamfi,M., Aerts,A., Altherr,M., Ashworth,L., Bajorek,E.,
            Black,S., Branscomb,E., Caenepeel,S., Carrano,A., Caoile,C.,
            Chan,Y.M., Christensen,M., Cleland,C.A., Copeland,A., Dalin,E.,
            Dehal,P., Denys,M., Detter,J.C., Escobar,J., Flowers,D.,
            Fotopulos,D., Garcia,C., Georgescu,A.M., Glavina,T., Gomez,M.,
            Gonzales,E., Groza,M., Hammon,N., Hawkins,T., Haydu,L., Ho,I.,
            Huang,W., Israni,S., Jett,J., Kadner,K., Kimball,H., Kobayashi,A.,
            Larionov,V., Leem,S.H., Lopez,F., Lou,Y., Lowry,S., Malfatti,S.,
            Martinez,D., McCready,P., Medina,C., Morgan,J., Nelson,K.,
            Nolan,M., Ovcharenko,I., Pitluck,S., Pollard,M., Popkie,A.P.,
            Predki,P., Quan,G., Ramirez,L., Rash,S., Retterer,J., Rodriguez,A.,
            Rogers,S., Salamov,A., Salazar,A., She,X., Smith,D., Slezak,T.,
            Solovyev,V., Thayer,N., Tice,H., Tsai,M., Ustaszewska,A., Vo,N.,
            Wagner,M., Wheeler,J., Wu,K., Xie,G., Yang,J., Dubchak,I.,
            Furey,T.S., DeJong,P., Dickson,M., Gordon,D., Eichler,E.E.,
            Pennacchio,L.A., Richardson,P., Stubbs,L., Rokhsar,D.S.,
            Myers,R.M., Rubin,E.M. and Lucas,S.M.
  TITLE     The DNA sequence and biology of human chromosome 19
  JOURNAL   Nature 428 (6982), 529-535 (2004)
   PUBMED   15057824
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX396051.2, DY654838.1 and AI138384.1.
            
            On Sep 25, 2020 this sequence version replaced NM_001135580.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX396051.2, BX396050.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142680
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329493.6/ ENSP00000327950.4
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-251               BX396051.2         22-272
            252-505             DY654838.1         1-254               c
            506-654             AI138384.1         3-151               c
FEATURES             Location/Qualifiers
     source          1..654
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19p13.3"
     gene            1..654
                     /gene="TEKTIP1"
                     /gene_synonym="C19orf71"
                     /note="tektin bundle interacting protein 1"
                     /db_xref="GeneID:100128569"
                     /db_xref="HGNC:HGNC:34496"
     exon            1..87
                     /gene="TEKTIP1"
                     /gene_synonym="C19orf71"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..634
                     /gene="TEKTIP1"
                     /gene_synonym="C19orf71"
                     /note="uncharacterized protein C19orf71"
                     /codon_start=1
                     /product="tektin bundle-interacting protein 1"
                     /protein_id="NP_001129052.1"
                     /db_xref="CCDS:CCDS45918.1"
                     /db_xref="GeneID:100128569"
                     /db_xref="HGNC:HGNC:34496"
                     /translation="MQTLRQEAARPCIPSGTLEASFPAPLYSDDYLSLEGSRWPPAIR
                     QATRWKYTPMGRDAAGQLWYTGLTNSDAWEAWYNLPRAPASPFREAYNRWHSCYQHRE
                     CSMPSAYTQHLRETAWHDPIVPAQYQAPSTRWGSALWKDRPIRGKEYVLNRNRYGVEP
                     LWRASDYVPSLSAPQRPPGTTQNYREWVLEPYCPSTCQRSPPSLTPTPR"
     exon            88..326
                     /gene="TEKTIP1"
                     /gene_synonym="C19orf71"
                     /inference="alignment:Splign:2.1.0"
     exon            327..452
                     /gene="TEKTIP1"
                     /gene_synonym="C19orf71"
                     /inference="alignment:Splign:2.1.0"
     exon            453..654
                     /gene="TEKTIP1"
                     /gene_synonym="C19orf71"
                     /inference="alignment:Splign:2.1.0"
     regulatory      630..635
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TEKTIP1"
                     /gene_synonym="C19orf71"
                     /note="hexamer: GATAAA"
     polyA_site      654
                     /gene="TEKTIP1"
                     /gene_synonym="C19orf71"
                     /note="major polyA site"
ORIGIN      
        1 agacatgcaa accctcaggc aagaggctgc acggccctgt atcccctcgg ggaccctcga
       61 ggccagcttc ccagcaccgc tgtacagcga tgactacctg tccctggagg gttcccgctg
      121 gccaccagcc atcaggcagg ccacacgctg gaagtacacg cccatgggac gggacgcagc
      181 cggccagctg tggtacacag gcctgaccaa ctcggacgcc tgggaagcct ggtacaacct
      241 gccacgggcc ccggccagcc ccttccgcga ggcctacaac cgctggcaca gctgctacca
      301 acaccgtgag tgcagcatgc catcggccta cacccagcac ctgcgggaga ccgcctggca
      361 tgaccccatc gtccctgccc agtaccaggc ccccagcacc cggtggggga gcgcgctgtg
      421 gaaagacagg ccaatccggg gcaaggaata cgtgctcaac aggaaccggt acggggtgga
      481 gccactgtgg agggcatcag actacgtgcc ctccctgtcg gcaccccagc gcccgcccgg
      541 caccacccag aactaccggg agtgggtcct ggaaccatac tgcccctcca cctgccagcg
      601 gtccccgcct tccctcacac ccactccccg ataaaggcat gctaccagga tgca
//
