LOCUS       NM_144674               1597 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens tektin 5 (TEKT5), mRNA.
ACCESSION   NM_144674
VERSION     NM_144674.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1597)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK057433.1 and AC007595.9.
            
            On May 17, 2019 this sequence version replaced NM_144674.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.215461.1, AK057433.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000283025.7/ ENSP00000283025.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1594              AK057433.1         16-1609
            1595-1597           AC007595.9         41002-41004         c
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.13"
     gene            1..1597
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /note="tektin 5"
                     /db_xref="GeneID:146279"
                     /db_xref="HGNC:HGNC:26554"
                     /db_xref="MIM:618686"
     exon            1..621
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..1515
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /codon_start=1
                     /product="tektin-5"
                     /protein_id="NP_653275.1"
                     /db_xref="CCDS:CCDS10542.1"
                     /db_xref="GeneID:146279"
                     /db_xref="HGNC:HGNC:26554"
                     /db_xref="MIM:618686"
                     /translation="MEFLGTTQTASYCGPKKCCGLTSLPAVQAPVIQECYQPYYLPGY
                     RYLNSWRPSLFYKIANVQTCPDESTSTLRPPTILPTLRSALFSRYSPHDWDQSNQLQV
                     RGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELD
                     RLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREV
                     DLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCI
                     SFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQ
                     FTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQ
                     TRLECRTRRPNMELCRDIPQLKLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRL
                     EHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGHT"
     exon            622..705
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /inference="alignment:Splign:2.1.0"
     exon            706..776
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /inference="alignment:Splign:2.1.0"
     exon            777..920
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1143
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1298
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1597
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1574..1579
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /note="hexamer: AGTAAA"
     polyA_site      1597
                     /gene="TEKT5"
                     /gene_synonym="CT149"
                     /note="major polyA site"
ORIGIN      
        1 ggtgatgcct ttggctcctt gagctgagtt ttgcccgagt ggggctcatg agggaggatg
       61 gagtttcttg ggactactca gaccgccagt tactgtggtc ccaagaaatg ctgtggcttg
      121 acctcactgc cagctgtaca ggcgccagtg atccaggaat gctatcagcc ctactacctg
      181 cccgggtacc gctacctcaa ttcatggagg cctagcctct tctacaagat agccaacgtc
      241 cagacctgcc cggacgagag caccagtacc ctgcggccgc ccaccatcct gcccacactg
      301 cgctccgcac tcttctctcg ctatagcccc cacgactggg accagtccaa ccagctgcag
      361 gtgcgtgggg ccgaggcctc ccggctgtgg gccagccggc tgacggatga ctccatgagg
      421 ctcttgcagg acaaggacca gctgacgcac cagatgcagg agggcacctg ccggaacctg
      481 ggccagaggc tgtcggacat tggcttctgg aagtcagagc tgagctatga gctggacagg
      541 cttctgactg agaaccagaa cttggagacg gtcaagaggc ggctggagtg cgcggccaat
      601 gaggtgaact gcccattgca ggtggccttg gagtgtctgt accatcgaga gaagaggatt
      661 gggattgatt tggtccatga caacgtggag aaaaacctta tccgggaagt ggatttgcta
      721 aaatgttgcc aagaacagat gagaaaatta gctcaaagaa ttgatatcca gatgcgggat
      781 aaccgggatg ctcagcacgt gctggagagg gacctcgaag acaaaagctc ggcccagtgt
      841 atcgatgaga agtgctttaa cctgagaaat acgtcagact gcatcagctt cttccacggc
      901 atggagaaaa ttgacggcac gatctccgta cctgagacct gggccaagtt cagtaacgac
      961 aacatcaaac actctcagaa catgcgggcc aactccatcc agctgcggga ggaggcggag
     1021 cacctctttg agaccttgtc ggatcagatg tggaggcagt tcacagacac caacctggcc
     1081 ttcaacgccc gcatctctga ggtgacggat gtgaagaata agctgcagac gcagctggcg
     1141 aagacgctgc aggagatctt ccaggccgag aacaccatca tgctgctgga aaggtccatc
     1201 atggccaagg agggcccgct gaaggtggcc cagacaaggc tggagtgccg gacccggcgc
     1261 cccaacatgg agctgtgcag ggacatcccg cagttgaagc tggtgaacga ggtgttcacc
     1321 atcgacgaca ccctgcagac cctcaagctg cggctgcggg agacacagga cacgctgcag
     1381 ctgctggtca tgaccaagtg ccggctggag cacgagctcg ccatcaaggc caacaccctc
     1441 tgcatcgaca aggagaagtg catgggcatg cgtaagacct tcccctgcac cccgcgcctg
     1501 gtgggccaca cctgagcacc gccctggcgc ctcattccgc gctggcgtaa aattggaaaa
     1561 ggctgagaaa caaagtaaaa cagtattttg tttgaaa
//
