LOCUS       NM_018393               2649 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens t-complex 11 like 1 (TCP11L1), transcript variant 1,
            mRNA.
ACCESSION   NM_018393
VERSION     NM_018393.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2649)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2649)
  AUTHORS   Mick,E., McGough,J., Deutsch,C.K., Frazier,J.A., Kennedy,D. and
            Goldberg,R.J.
  TITLE     Genome-wide association study of proneness to anger
  JOURNAL   PLoS One 9 (1), e87257 (2014)
   PUBMED   24489884
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2649)
  AUTHORS   Bharti,P., Schliebs,W., Schievelbusch,T., Neuhaus,A., David,C.,
            Kock,K., Herrmann,C., Meyer,H.E., Wiese,S., Warscheid,B., Theiss,C.
            and Erdmann,R.
  TITLE     PEX14 is required for microtubule-based peroxisome motility in
            human cells
  JOURNAL   J Cell Sci 124 (Pt 10), 1759-1768 (2011)
   PUBMED   21525035
REFERENCE   4  (bases 1 to 2649)
  AUTHORS   Pelak,K., Goldstein,D.B., Walley,N.M., Fellay,J., Ge,D.,
            Shianna,K.V., Gumbs,C., Gao,X., Maia,J.M., Cronin,K.D.,
            Hussain,S.K., Carrington,M., Michael,N.L. and Weintrob,A.C.
  CONSRTM   Infectious Disease Clinical Research Program HIV Working Group;
            National Institute of Allergy and Infectious Diseases Center for
            HIV/AIDS Vaccine Immunology (CHAVI)
  TITLE     Host determinants of HIV-1 control in African Americans
  JOURNAL   J Infect Dis 201 (8), 1141-1149 (2010)
   PUBMED   20205591
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
            Erratum:[J Infect Dis. 2010 Aug 15;202(3):501]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA088926.1, AK090646.1, BP281502.1 and AC131263.6.
            
            On Nov 23, 2018 this sequence version replaced NM_018393.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.179099.1,
                                           SRR1803611.217148.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000334274.9/ ENSP00000335595.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-319               DA088926.1         157-475
            320-471             AK090646.1         458-609
            472-625             BP281502.1         439-592
            626-2013            AK090646.1         764-2151
            2014-2649           AC131263.6         134413-135048       c
FEATURES             Location/Qualifiers
     source          1..2649
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p13"
     gene            1..2649
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /note="t-complex 11 like 1"
                     /db_xref="GeneID:55346"
                     /db_xref="HGNC:HGNC:25655"
     exon            1..221
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     exon            222..408
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..1775
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /note="t-complex 11, testis-specific-like 1"
                     /codon_start=1
                     /product="T-complex protein 11-like protein 1"
                     /protein_id="NP_060863.3"
                     /db_xref="CCDS:CCDS7882.1"
                     /db_xref="GeneID:55346"
                     /db_xref="HGNC:HGNC:25655"
                     /translation="MSENLDKSNVNEAGKSKSNDSEEGLEDAVEGADEALQKAIKSDS
                     SSPQRVQRPHSSPPRFVTVEELLETARGVTNMALAHEIVVNGDFQIKPVELPENSLKK
                     RVKEIVHKAFWDCLSVQLSEDPPAYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVL
                     DLDLIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFREIFSV
                     LDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWLEEASEDLM
                     TQKYKHALPVGGMAAGSGDMPRLSPVAVQNYAYLKLLKWDHLQRPFPETVLMDQSRFH
                     ELQLQLEQLTILGAVLLVTFSMAAPGISSQADFAEKLKMIVKILLTDMHLPSFHLKDV
                     LTTIGEKVCLEVSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFL
                     ETYLASGHQKPLPTVPGGLSPVQRELEEVAIKFARLVNYNKMVFCPYYDAILSKILVR
                     S"
     exon            409..541
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     exon            542..662
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     exon            663..883
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     exon            884..1020
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1217
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1399
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1572
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..2649
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2622..2627
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /note="hexamer: AATACA"
     polyA_site      2649
                     /gene="TCP11L1"
                     /gene_synonym="dJ85M6.3"
                     /note="major polyA site"
ORIGIN      
        1 agtctcctcc ttcctgatgc tgagaagcgg ccgctctgac cgctgcccac ccgagtcggg
       61 ctgggaggac cgcccgccgc gtggcgaggg atgcggcctc ggaggggcag aggctgaacc
      121 gcccctgcct gccgcgcatc cctccggctt ccgccgcggc gccagcccgc gcctgattcg
      181 cggcgggagc ggcaggaggg agaacgccga ctccgtggca ggaaagtgaa taaacttaat
      241 tgagaatgtc tgaaaacctt gacaagtcca atgtaaatga agcaggaaaa tcaaaatcca
      301 atgattctga ggaaggcctc gaagatgctg tggaaggtgc tgatgaagcc ttacaaaaag
      361 caataaagtc agactcctcc agcccccaaa gagtgcagag acctcactct agtcctcctc
      421 gctttgtgac agtagaagaa cttctagaga cagcgagagg tgtcaccaac atggctctag
      481 cccatgaaat tgtagtaaat ggagactttc agattaaacc agttgaatta ccagaaaaca
      541 gcttgaagaa gagagtaaag gagattgtac ataaagcgtt ttgggattgc ttgagtgtgc
      601 agctaagtga agatccccca gcatatgacc atgctatcaa acttgtagga gaaatcaaag
      661 agactctctt atctttcttg ctgcctggtc atactagact gagaaaccag ataacagaag
      721 tcttggatct ggatctgata aagcaggaag cagagaatgg ggcgctagac atttccaagc
      781 tggcagaatt cattattggc atgatgggga cactgtgtgc acctgctcga gatgaggaag
      841 ttaagaaact aaaggacatt aaggaaatag tgcccctttt cagagaaatt ttttctgtgt
      901 tggacctaat gaaagtggac atggccaact ttgctatcag tagcatcagg cctcatctca
      961 tgcagcagtc agttgaatac gaaaggaaga agtttcaaga gattttggag aggcaaccaa
     1021 attccctgga ctttgtcacc cagtggctgg aagaagcctc agaggacctt atgactcaga
     1081 agtataaaca cgccctgcca gtggggggaa tggctgctgg ctctggggac atgcccaggc
     1141 tgagccctgt tgctgtccag aattacgctt acctgaagct tctgaagtgg gaccacctcc
     1201 agaggccgtt ccccgaaaca gttttaatgg accagtctcg cttccacgag ctccagttgc
     1261 agctggaaca actgaccatc ctgggggctg tgttgctggt caccttcagc atggcagcgc
     1321 caggaatttc cagccaggcc gactttgctg agaaactcaa gatgattgtg aagattttgc
     1381 taacagatat gcacctgccc tccttccatc tgaaggacgt cctcactacc atcggggaga
     1441 aggtgtgcct ggaggtgagc agctgcctct ccctgtgtgg gtcctctccc ttcaccacgg
     1501 acaaggagac cgtgctcaag ggccagatcc aggccgtggc cagtcccgat gaccccattc
     1561 gcaggatcat ggaatctcga atcctgacct tcttagaaac ctaccttgcc tcgggtcatc
     1621 agaagccatt gcccacagtc cctgggggac tcagtccagt tcagagagag ctggaggaag
     1681 ttgctattaa atttgctcgc ctggtcaact ataacaagat ggtcttctgt ccctactacg
     1741 atgcaatcct gagtaagatc ctcgtccgat cctaacgtgt atgcacccta cagcagcagt
     1801 attactcact agccacagaa tacctgttct gtactctaat gttgcattgg aaaatggcta
     1861 tatagtacat gtctatttaa cagcaccgat tccaaaggga agaatattgt gtatcactgt
     1921 tgaaaagact tgttgagaaa tccactgaat tctattttga gagattgtat ttatgagtgc
     1981 aagtttacaa atcaaagaag cattttgttc tcgagtttta caggtaacac tcagctgttg
     2041 tctccactcc tcccccatca tgtccttcca aggaggctgg gacctctctc ttctgcaatc
     2101 tgggtagttc tttcagatgc ctcatgctga gctgacggcc atccaagcgc aaaagagacc
     2161 aagccatggc ctcacctcct gccctccctc agacagcctt gtccctcacc cctcccttct
     2221 ggtatttttg ttagaagggc tatataacgt cttattgcca ttttctcccc ctatttattg
     2281 cttcctccct gcctggccta gccagggctc ccaagccctt ttttctagag gagagttatt
     2341 tgtctctctc tctttttttt tttactttct tttttgtatt taaacattct tttaaccttc
     2401 ccccaaagat acagttattg gactttaaaa agcttgttct tttatacaaa attactcctg
     2461 catctggttg agagcagtta tgacttatga gatctagtga aaggaaagtc tttgactttc
     2521 aagccttgaa agtcaaggag gaaatgtatt gaaaaatagt ttactgtaat gtgaacgaag
     2581 agaaatgtct ggaattctta ctgaaaaatt gaccctgaga caatacacag atgtgatgat
     2641 tgaattaaa
//
