LOCUS       NM_001193502            2451 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens transcription factor 24 (TCF24), mRNA.
ACCESSION   NM_001193502 XM_001715521 XM_001715561 XM_001732830
VERSION     NM_001193502.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2451)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2451)
  AUTHORS   McLellan,A.S., Langlands,K. and Kealey,T.
  TITLE     Exhaustive identification of human class II basic helix-loop-helix
            proteins by virtual library screening
  JOURNAL   Mech Dev 119 Suppl 1, S285-S291 (2002)
   PUBMED   14516699
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC110998.4, AW028708.1 and CX788264.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001193502.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: CX788264.1, SRR12514507.445108.1
                                    [ECO:0000331]
            RNAseq introns       :: partial sample support SAMEA1968968,
                                    SAMEA1970526 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000563496.2/ ENSP00000455444.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 AC110998.4         63882-63882         c
            2-386               AW028708.1         27-411              c
            387-647             AC110998.4         62807-63067         c
            648-992             CX788264.1         20-364
            993-2451            AC110998.4         47792-49250         c
FEATURES             Location/Qualifiers
     source          1..2451
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8q13.1"
     gene            1..2451
                     /gene="TCF24"
                     /gene_synonym="bHLHa25; TCF-24"
                     /note="transcription factor 24"
                     /db_xref="GeneID:100129654"
                     /db_xref="HGNC:HGNC:32275"
     exon            1..263
                     /gene="TCF24"
                     /gene_synonym="bHLHa25; TCF-24"
                     /inference="alignment:Splign:2.1.0"
     exon            264..374
                     /gene="TCF24"
                     /gene_synonym="bHLHa25; TCF-24"
                     /inference="alignment:Splign:2.1.0"
     exon            375..787
                     /gene="TCF24"
                     /gene_synonym="bHLHa25; TCF-24"
                     /inference="alignment:Splign:2.1.0"
     CDS             398..901
                     /gene="TCF24"
                     /gene_synonym="bHLHa25; TCF-24"
                     /codon_start=1
                     /product="transcription factor 24"
                     /protein_id="NP_001180431.1"
                     /db_xref="CCDS:CCDS59103.1"
                     /db_xref="GeneID:100129654"
                     /db_xref="HGNC:HGNC:32275"
                     /translation="MDRGRPAGSPLSASAEPAPLAAAIRDSRPGRTGPGPAGPGGGSR
                     SGSGRPAAANAARERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLT
                     RSLQDDAEAPADAGLGALRGDGYLHPVKKWPMRSRLYIGATGQFLKHSVSGEKTNHDN
                     TPTDSQP"
     exon            788..2451
                     /gene="TCF24"
                     /gene_synonym="bHLHa25; TCF-24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2428..2433
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TCF24"
                     /gene_synonym="bHLHa25; TCF-24"
                     /note="hexamer: AATAAA"
     polyA_site      2451
                     /gene="TCF24"
                     /gene_synonym="bHLHa25; TCF-24"
                     /note="major polyA site"
ORIGIN      
        1 aagccgcctc agcccccggc gtagcctctc cggtgggcca ggtcctccgc ccgacctgcc
       61 ttagccggtc ggagcacaca cgcctggccg cggggcgccc gcataaaagt cacagccagc
      121 ggaggttgga aacagccgtc gacttgggca tcggccggac gaggatggag tgaccagcgc
      181 ggccctggcc acacaggccc tgctccacgc ccctcgcccg ccctcacgac ggagcggagc
      241 tccactcagc cgctccagga aaggaagccc aagaactccg gagttccgca actctcccca
      301 gacgtccgga agcaaatcgc gtcccaggca aaacgagctc gcttgagagc gcccttagcc
      361 ccgttgggct gctgcgcgcg cggcgcggga agctgccatg gaccgcggcc gcccagcggg
      421 cagccccctc agcgccagcg ccgagcccgc gcccctggcc gccgccatcc gcgactcgcg
      481 tcccgggcgg accgggccgg ggccggcggg ccctgggggc ggctcgcgtt ccgggagcgg
      541 gcggccggcg gcggcgaatg cggcgcggga gcgcagccgg gtgcagaccc tgcggcacgc
      601 tttcctggag ctgcagcgca cgctgccgtc cgtgccgccc gacaccaagc tgtccaagct
      661 ggacgtgctg ctgctggcca ccacctacat cgcgcatctc acccgcagcc tgcaggacga
      721 cgccgaggcg ccggcggacg ccgggttggg cgccctgcgc ggcgatggct acctgcaccc
      781 ggtcaagaaa tggcccatgc gatcaagatt gtacatcggt gctactggtc agtttctgaa
      841 gcattctgtt tctggagaaa aaacaaatca tgacaacact ccaacagact cacagcctta
      901 ggctctcccc tggtgggggc tggtagaagt ggtggctatt gtttttaaat actatgacat
      961 aattctatat ttattatatg agacataaca aaatttctga aagtttacat gtgaacccat
     1021 agttggatgt tcaggtttat ctgtctaaat gtggaatgaa ataatcagtg ttatataaaa
     1081 cacacagctt atctgttcag tgtgagagtc actactatat agtgcaagag aaattattag
     1141 aaaaaagtca catgaaagca aacaattgtg tatatagcta aagaatgcaa tatagatatt
     1201 gctatagtgt atctattaca aacagaaaag ttcatatcta ttggtgcagt cttcctagtt
     1261 taaaaagata aaaatctgtg tttataatat acgagtattc cttttttgtg aaaaccatac
     1321 tgttcttaag ttgatctaag acaccatttc aattgaagaa aactgttgca gtaatatgaa
     1381 gatgcaataa attcaataag tagttacttt tccctcttag aaaacttgtt tggagtatta
     1441 gaaatggttt gctcagagga cagggcttgg tcaccttcct agagggttat tctgtatctt
     1501 acagtgtttg caacttgtgg aaggcactgg gaatccctgc agtccagtgt gaacaggaga
     1561 ccaggtgtca gcggacagca gagttcacaa tgtaggtgca tgtcaccaca cctggctaat
     1621 tcttttattt tttgtagaga tggagtctca ctgtgttgcc taggctactc ttgaaatcct
     1681 ggctcaataa atcctcctgc ctcacctacc aaagtgttgg gattataggc tagagccacc
     1741 gtgcctggcc cagttttatt gttttaatgt gaatatactc ataatgtgac agaagcatat
     1801 ctttttgcaa gaaagatata taatagttct ctacatatta atatgtagaa aagtacttgc
     1861 atatttaaat atttgtaaac atatttacct actcatggaa agaaataaaa agtaaaatga
     1921 gatttggatt cagccattca ctattataag ttattgacat aagaagtgct aaaaagaatc
     1981 tttatcctaa ggaatgaaat caaaacttct tcaaagttac ctcaaactga attgtaaaca
     2041 ctaaatttaa cagcaagaat ttcagaaaaa tgattttctt gctaataatt cttaagattt
     2101 attagtttgg ctagttttta aagcatttaa ctggggaaaa aactatgtgt tgaataatta
     2161 gatttctaag tcatcctgtt aaatagttag tagagctttg cctttgatgg tattactttt
     2221 taattcttct catccagtta caagttgtat taatgccaaa gaagtgtatt tgttacagat
     2281 tttcataaca ttttattaaa ttgctagata tgatgatagg ttttggtatg tttacagagg
     2341 agaaattgca tattttcact cagattcaaa agagcatgct cttttaatgc tttaatggtg
     2401 aatggtcatg ataagaggta ttataaaaat aaagtactaa tttgaaaatt a
//
