LOCUS       NM_006453               6783 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens transducin beta like 3 (TBL3), mRNA.
ACCESSION   NM_006453
VERSION     NM_006453.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6783)
  AUTHORS   Singh,S., Vanden Broeck,A., Miller,L., Chaker-Margot,M. and
            Klinge,S.
  TITLE     Nucleolar maturation of the human small subunit processome
  JOURNAL   Science 373 (6560), eabj5338 (2021)
   PUBMED   34516797
REFERENCE   2  (bases 1 to 6783)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 6783)
  AUTHORS   Yoshida,T., Kato,K., Yokoi,K., Oguri,M., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
  TITLE     Association of genetic variants with hemorrhagic stroke in Japanese
            individuals
  JOURNAL   Int J Mol Med 25 (4), 649-656 (2010)
   PUBMED   20198315
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   4  (bases 1 to 6783)
  AUTHORS   Yoshida,T., Kato,K., Yokoi,K., Oguri,M., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nozawa,Y. and Yamada,Y.
  TITLE     Association of gene polymorphisms with chronic kidney disease in
            Japanese individuals
  JOURNAL   Int J Mol Med 24 (4), 539-547 (2009)
   PUBMED   19724895
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   5  (bases 1 to 6783)
  AUTHORS   Andersen,J.S., Lam,Y.W., Leung,A.K., Ong,S.E., Lyon,C.E.,
            Lamond,A.I. and Mann,M.
  TITLE     Nucleolar proteome dynamics
  JOURNAL   Nature 433 (7021), 77-83 (2005)
   PUBMED   15635413
REFERENCE   6  (bases 1 to 6783)
  AUTHORS   Scherl,A., Coute,Y., Deon,C., Calle,A., Kindbeiter,K.,
            Sanchez,J.C., Greco,A., Hochstrasser,D. and Diaz,J.J.
  TITLE     Functional proteomic analysis of human nucleolus
  JOURNAL   Mol Biol Cell 13 (11), 4100-4109 (2002)
   PUBMED   12429849
REFERENCE   7  (bases 1 to 6783)
  AUTHORS   Andersen,J.S., Lyon,C.E., Fox,A.H., Leung,A.K., Lam,Y.W., Steen,H.,
            Mann,M. and Lamond,A.I.
  TITLE     Directed proteomic analysis of the human nucleolus
  JOURNAL   Curr Biol 12 (1), 1-11 (2002)
   PUBMED   11790298
REFERENCE   8  (bases 1 to 6783)
  AUTHORS   Weinstat-Saslow,D.L., Germino,G.G., Somlo,S. and Reeders,S.T.
  TITLE     A transducin-like gene maps to the autosomal dominant polycystic
            kidney disease gene region
  JOURNAL   Genomics 18 (3), 709-711 (1993)
   PUBMED   8307582
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC005363.1, BC010231.1 and
            AC005606.3.
            
            On May 17, 2019 this sequence version replaced NM_006453.2.
            
            Summary: The protein encoded by this gene has sequence similarity
            with members of the WD40 repeat-containing protein family. The WD40
            group is a large family of proteins, which appear to have a
            regulatory function. It is believed that the WD40 repeats mediate
            protein-protein interactions and members of the family are involved
            in signal transduction, RNA processing, gene regulation, vesicular
            trafficking, cytoskeletal assembly and may play a role in the
            control of cytotypic differentiation. This gene has multiple
            polyadenylation sites. It might have multiple alternatively spliced
            transcript variants but the variants have not been fully described
            yet. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.260451.1,
                                           SRR1803614.197805.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000568546.6/ ENSP00000454836.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AC005363.1         73737-73746
            11-2604             BC010231.1         1-2594
            2605-6783           AC005606.3         37842-42020
FEATURES             Location/Qualifiers
     source          1..6783
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..6783
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /note="transducin beta like 3"
                     /db_xref="GeneID:10607"
                     /db_xref="HGNC:HGNC:11587"
                     /db_xref="MIM:605915"
     exon            1..153
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..2539
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /note="WD-repeat protein SAZD; WD repeat-containing
                     protein SAZD"
                     /codon_start=1
                     /product="transducin beta-like protein 3"
                     /protein_id="NP_006444.2"
                     /db_xref="CCDS:CCDS10453.1"
                     /db_xref="GeneID:10607"
                     /db_xref="HGNC:HGNC:11587"
                     /db_xref="MIM:605915"
                     /translation="MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCG
                     TRVNILEVASGAVLRSLEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTR
                     LWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFH
                     PDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKI
                     CIIWDLQSCQATRTVPVFESVEAAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEA
                     ASGQCVYTQAQPPGPGQELTHCTLAHTAGVVLTATADHNLLLYEARSLRLQKQFAGYS
                     EEVLDVRFLGPEDSHVVVASNSPCLKVFELQTSACQILHGHTDIVLALDVFRKGWLFA
                     SCAKDQSVRIWRMNKAGQVMCVAQGSGHTHSVGTVCCSRLKESFLVTGSQDCTVKLWP
                     LPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWAL
                     PQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASV
                     LKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGA
                     SDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTV
                     LTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVTWNTNSRHCHEAQAVLGVLLR
                     REAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAFLDFLWHNMKLPVPAAAPT
                     PWETHKGALP"
     exon            154..205
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            206..301
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            302..349
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            350..491
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            492..576
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            577..747
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            748..823
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            824..917
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1099
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            1100..1241
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1300
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            1301..1404
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1552
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1783
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1854
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            1855..2011
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            2012..2070
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            2071..2174
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            2175..2246
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            2247..2405
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     exon            2406..6783
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2519..2524
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /note="hexamer: CATAAA"
     polyA_site      2538
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /note="major polyA site"
     regulatory      2584..2589
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /note="hexamer: CATAAA"
     polyA_site      2604
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /note="major polyA site"
     regulatory      2779..2784
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /note="hexamer: AACAAG"
     polyA_site      2806
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
     polyA_site      5553
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
     polyA_site      5624
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
     polyA_site      5642
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
     regulatory      6620..6625
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
                     /note="hexamer: AATACA"
     polyA_site      6638
                     /gene="TBL3"
                     /gene_synonym="SAZD; UTP13"
ORIGIN      
        1 gcagcgcgcc gggagtgtgg cgttctgtga agagttcggt gctaacctcc ctcacgcggc
       61 ggtggctgcc gggaccctag caggtttcag ctggagcggc ggcggcggca acatggcaga
      121 gaccgcggcc ggagtgggcc gcttcaagac caactatgct gtggagcgca aaattgagcc
      181 tttctacaag ggcggaaaag cacagctgga ccagactggc cagcacctct tctgcgtctg
      241 tggcaccaga gtcaacattc tggaagtggc ctcgggggcc gtgctgcgga gtctggagca
      301 ggaggaccag gaggacatca ctgcctttga cctcagccct gacaacgagg tgctggtgac
      361 agccagtcgg gcattgctgc tggctcagtg ggcctggcaa gagggcagcg ttacccgcct
      421 gtggaaggcg atacacacgg cccccgtggc caccatggcc ttcgacccca cctccactct
      481 gctagccaca ggtggctgtg atggggccgt gcgcgtctgg gacatcgtgc ggcactacgg
      541 gacacaccac ttccgaggct cgcccggtgt cgtgcaccta gtggccttcc acccggaccc
      601 tacacgcctg ctgctcttct cctcggccac ggatgccgcc atccgcgtgt ggtcactgca
      661 ggaccggtca tgcctggctg tgctgactgc ccactacagc gccgtcacct cactggcctt
      721 cagcgccgac ggccacacca tgctcagctc cggccgtgac aagatatgta tcatctggga
      781 ccttcagagc tgccaggcca cgaggaccgt gcctgtgttt gagagcgtgg aggctgctgt
      841 gctgttgcca gaggagccag tgtcccagct gggtgtgaag tccccagggc tgtactttct
      901 gacagctggc gaccaaggca ctctgcgcgt gtgggaggca gcttctgggc agtgtgtgta
      961 cacgcaggcc cagccgccgg gccctgggca ggagctgacc cactgcaccc tggcacacac
     1021 cgccggcgtg gtcctcaccg ccaccgccga ccacaacctg ttgctctacg aggctcgctc
     1081 cctgcggctg cagaaacagt tcgctggcta cagtgaggag gttttggatg tccggtttct
     1141 tgggcccgag gactcccacg ttgtcgtggc ctccaatagc ccctgcctaa aagtgtttga
     1201 gctgcagacg tcagcctgcc agatcctcca cggccacacg gatatcgtcc tggccctgga
     1261 tgtgttccgg aaggggtggc tctttgccag ctgtgccaag gatcagagcg tccgtatctg
     1321 gagaatgaac aaggctggcc aggtgatgtg cgtggctcag ggttccggtc acacacacag
     1381 tgtgggcacc gtctgctgct ctaggctgaa ggagtccttc ctggtgacag gcagccagga
     1441 ctgcactgtg aagctgtggc ctcttcccaa agccttgctg tccaagaaca cagccccaga
     1501 caacggccct atcctcctgc aggcccagac cactcagcgc tgccatgata aggacatcaa
     1561 cagcgtggct attgccccca acgacaagct gctggccaca ggctcacagg accgcacggc
     1621 caagctctgg gccctgccac agtgccagct gctgggtgtc ttctcaggcc accggcgtgg
     1681 cctctggtgc gtccagttct ctcccatgga ccaggtgctg gccacggcct cagctgatgg
     1741 caccatcaag ctctgggcac tccaggactt cagctgtctc aagacatttg aggggcacga
     1801 tgcttctgtg ctgaaggtgg cctttgtgag ccgtggcacg cagctgctgt ccagcggttc
     1861 ggatggcctc gtgaagctct ggaccatcaa gaacaacgag tgtgtgcgga cgctggatgc
     1921 ccacgaggac aaggtctggg ggctgcactg cagccggctg gacgaccacg ccctcactgg
     1981 ggccagtgac tcccgagtca tcctctggaa ggatgtgacc gaggcggagc aggcagagga
     2041 gcaggccagg caagaggagc aggtggtcag gcagcaagag ctggacaacc tgctgcatga
     2101 gaagcggtac ctgcgggcgc tgggcctggc catctccctg gatcggcccc acaccgtgct
     2161 gactgtcatc caggccatcc ggagggaccc tgaggcctgc gagaagctgg aagccaccat
     2221 gctccgactg cggcgcgacc agaaagaggc cctgctgcgc ttctgcgtca cgtggaacac
     2281 caactcgcgg cactgccacg aggcccaggc cgtgctgggt gtgctcttga ggcgagaggc
     2341 ccccgaggag ctgctggcct acgaaggcgt gcgggcagcg cttgaggccc tgctgcccta
     2401 cactgagcgg cactttcagc ggctcagcag gaccctccag gccgccgctt tcttggactt
     2461 cctgtggcac aacatgaagc tccctgtgcc ggccgccgcc cccaccccct gggaaaccca
     2521 taaaggcgca ctgccctagc cggtccggcc tctctccagt ccatcctgaa cccctggaaa
     2581 acccataaag gccgctctcc tggccggctc tgtctctctg gactgcagtc cagcccccca
     2641 ccctggccaa caccctacct agccagccag aagggcactg gagctgatgg tctcggccct
     2701 gccacgccca tcccgcaccc tggcctggca gagatccagc ccgcggctcc gcacgcttag
     2761 acggtggggg tcatgcagaa caagctttac tcagaggaac agcaaatggc cccctcccat
     2821 ccctgctggc cagggagatc cgccctcccc gctcctcccc agccctggga tggcgcggtc
     2881 catcccctca tcgggatcct cgcgctcact gctccgtcgt ggggtgcggc acagagtcca
     2941 cgcaccctcg agggcggccc tggcgccgtg ggcgccgctc cagggccctg cgtgtgacgg
     3001 tgcagcagcg gctctggatg gcgcccggcg aaggtcgggt gggcacggtg gggggagggg
     3061 cggtggcctg ggagggttca gggaagcccc gggcctcacc cgccgggtcg tctcctccac
     3121 ggaaccccgt cccgctcagg agagcgccca gcccttccgg ccgcagcagc accgcgggga
     3181 gtaggcccgc ccggtcgccg tacctgcgag gggcggggtg tggttagggc cccgcccgcc
     3241 tcggctagcc tgccctgccc acgcccgctc ccgcgtacct gcatagccac cagccgcggt
     3301 ctgacgtttc caacacgcgc acgcgcgccc ccgcgggcac ggacagctca tctgcgcggc
     3361 tgctctcgta ggcgcgggaa gcacagaact ggggacctgg tgggagtggg tgtttggagt
     3421 caccgcgggg ccacagagga cgaggcccgc ccgcaccctt ctccacattc tccttgcttg
     3481 agtctgctga cggcggggcc gctctaagac cggttcgggg cttcctctag gtgcggagac
     3541 caagcacggg ctcctggccc gccctgcccg cggtgcttct ggcccagtct tgccacacgg
     3601 tcaagccgca gtggtggcgt gaggggtggg gttaggcgca taccgctgct ccctagggac
     3661 gggcctccct cccggccttg gcccggggcc gcctcctcca ggtagggcgc tggaaaccag
     3721 gcggtctgcc ggtcttcgtt ctccaccagc caccagcctg tgcgcaagaa gcgggcaggg
     3781 actcaaatct cgaggctccc tcgggtccag gagcagagga gcaaatccct gggttcttgg
     3841 ggggccctac ctgaggggtg ccgcagcagc acgtccaggc tctcctgggc ctgcgcctga
     3901 aaaggcctat cccgcgtgtc ctgggtacag aagggctgca ggcagcgcag gctctgagcc
     3961 tccagactgt ggatggagag gcggcccgca gcgcgagaaa gaggctgctc ctctggggtg
     4021 ggcaggatca cccggctggg aagggcagcc cgtacgagtg agaggtaggc ggatggggag
     4081 ggtgaaactg ggggcgccac cccggcaaga ccgccagcct cccactctct gcccctattc
     4141 gctggctgtt cccccccacc ctggacctct cccagctcca aacgccgctg catgctggga
     4201 gtttggggcg agtcaggcac ctgccgggtg gcagcgcggg ctccaggtcc aggggttgcg
     4261 gtgcgaagaa gccagtgatc gtcgggctcc gtgccacgcg ctctgcagtc gccagcagcc
     4321 tccgagaata ggtttccaac agctgcaggc gcgccaggcc gcggctcgtg cgccccacgc
     4381 gtcccaacag tggtgcatct taaggcacca caaaaacgta ctgtgatacg ccgctttggg
     4441 cttcactggt ccctggcgcc cccaggcaag ccaccgcctt ccccgctccc gtacccaggc
     4501 tggcctgacc gagaagcttt gggagaacgc ggtcagatct ccgcagcagg cccgcctcca
     4561 ccgggaaggt ctccttgagg gtcttctgag ggcgggaacc agggcattgg tcttccagag
     4621 cccactgtgc acccttgaga gggcggggtc cctcacccgg atggcagggg ctgggagctt
     4681 cagcagggac gaagggcctc cagtgggagt cactgatggg aggcagtcca gtgggaggca
     4741 gccgcgtggg gaagccgcca ccgcggcatc agggtggccc agggtcactc accttgagct
     4801 gcctgaattc gtcccaactc ctgcgcacga aggtgtcgct gccgtctgac cagcgcacag
     4861 agaaggcaaa cgtctggggg acaaaaagtt gggagtgccg tggaggtgct ggtccaggca
     4921 cccccttcct atcccttggg gccactaagg acccagccag gtcttacttg gagcctcttg
     4981 atctgcacca gggctgcccc ttgcactgaa actgggtatc gggggcctgc catggctgtg
     5041 gcttccaggc tgcagattcc tgaaatgggc gaggaccctt ctgcctcccc gtgcttgaga
     5101 gggctctggg ggacccagaa aaccccctgg gatagaatcc tggcaacacc tcaagcctgt
     5161 ggggtccttg tggagccgcc ccagctgagt cctttgcagc tttcttgctg tcccccaagc
     5221 ccacgatctg ggggcaggag cacagggatt gggggacttc caggcagagc tgctgggagg
     5281 aagaagaaga atgagctttc cagccctgga ggcgtgcaag actgaagaag gggcgaaggg
     5341 taggcgggac tgctgcctgg ggccctcctg cctgcctctg gccacaggag gagggaggag
     5401 aaggcagggc taatcaaagc gccacctgtc ctgcccacct ctctggattc ccctaccctg
     5461 tgaggtaatt gccctgccag ggtgcgccca acaactttga actggcctgg ggatttctgt
     5521 gcagaaccaa ggactcagtg cttacagctt taagtgcttt gtctgactta atcctaatgc
     5581 tggaggaaag gtctcttaat gtccccaact catagaggag gaaatgtgtg ttaaatgcgt
     5641 aattattgtg agctgttcta tacatgctgg gggaggggca gacctcacag gctcacccca
     5701 ggggttcccc tgcagtgagg agacttgggg taggagaaag agggcccatc tgtgcagtca
     5761 ctggcatttg gtgggtgggg gtggtggtca gggaagtggt cactagggct gttttgagaa
     5821 ccacctctca attcacgatt tgccatgact tactgcaaac atggcctggg cagaggctcg
     5881 cccaggtgcc ccacctctct ggctgcttcc ttatagttcg ggcttcggaa gccacattca
     5941 accctggcac acagtggttt ttcctcgtgc tggggccacc agttctgtgt tgggatgcac
     6001 ctactccagc cccttcaggg agcagtcagc ctctaaggca tccctccagg aagctgccct
     6061 ggctgcaaca aagggccttt gtgtgtctgt cccaccagca ctctctctca tgccctcaag
     6121 ctgtccctgg tcttggcatg ggcaatgaac acctgctcac atagggctga tttgcagggt
     6181 tcccccagcc agctgtcacc ttctccctgt ctcagctgag ggcccagctg acctggtggg
     6241 gtccagcgtg tgaacccagg ggagaccttg ctcccctgga agacaggaga agctggggag
     6301 gatttattca caagcagagg cctagaggga ttctgaggcc acctgcctac cccagctgac
     6361 agctcctgcc ccacacccca tcagccctgc atggtttcca ctttttcctc ccctaccctc
     6421 ttttcttgcc tgaatagtac accccaccct ccatctgtat gctcctcact tgcccctaca
     6481 aaatccactc caaggacaga cacagtgcct cacctgtaat ccaagtactt tgggaggccg
     6541 aggcaggggg attgcttgag ctcaggagtt cgagaccagt ctgggcaaca tgttgagacc
     6601 tccatctgtg ccccccaaaa atacaaaaat tagctgggcg tggtggcgtg tgcctgtagt
     6661 ctacttggga ggctgaggtg ggagatcact tgagcctaag cagtcgcggc tgcagtgaac
     6721 aagatcgcgc cactgcactc caccctgggt aacggaacaa gaccctgtct caaaaaaaaa
     6781 aaa
//
