LOCUS       NM_001349084            6548 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens TBC1 domain family member 5 (TBC1D5), transcript
            variant 14, mRNA.
ACCESSION   NM_001349084 XM_011534287
VERSION     NM_001349084.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6548)
  AUTHORS   Healy,M.D., McNally,K.E., Butkovic,R., Chilton,M., Kato,K.,
            Sacharz,J., McConville,C., Moody,E.R.R., Shaw,S.,
            Planelles-Herrero,V.J., Yadav,S.K.N., Ross,J., Borucu,U.,
            Palmer,C.S., Chen,K.E., Croll,T.I., Hall,R.J., Caruana,N.J.,
            Ghai,R., Nguyen,T.H.D., Heesom,K.J., Saitoh,S., Berger,I.,
            Schaffitzel,C., Williams,T.A., Stroud,D.A., Derivery,E.,
            Collins,B.M. and Cullen,P.J.
  TITLE     Structure of the endosomal Commander complex linked to
            Ritscher-Schinzel syndrome
  JOURNAL   Cell 186 (10), 2219-2237 (2023)
   PUBMED   37172566
REFERENCE   2  (bases 1 to 6548)
  AUTHORS   Tu,Y.X.I., Sydor,A.M., Coyaud,E., Laurent,E.M.N., Dyer,D.,
            Mellouk,N., St-Germain,J., Vernon,R.M., Forman-Kay,J.D., Li,T.,
            Hua,R., Zhao,K., Ridgway,N.D., Kim,P.K., Raught,B. and Brumell,J.H.
  TITLE     Global Proximity Interactome of the Human Macroautophagy Pathway
  JOURNAL   Autophagy 18 (5), 1174-1186 (2022)
   PUBMED   34524948
REFERENCE   3  (bases 1 to 6548)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   4  (bases 1 to 6548)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   5  (bases 1 to 6548)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (bases 1 to 6548)
  AUTHORS   Seaman,M.N., Harbour,M.E., Tattersall,D., Read,E. and Bright,N.
  TITLE     Membrane recruitment of the cargo-selective retromer subcomplex is
            catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP
            TBC1D5
  JOURNAL   J Cell Sci 122 (Pt 14), 2371-2382 (2009)
   PUBMED   19531583
  REMARK    GeneRIF: Membrane recruitment of the cargo-selective retromer
            subcomplex VPS35/29/26 is catalysed by the small GTPase Rab7 and
            inhibited by the Rab-GAP TBC1D5.
REFERENCE   7  (bases 1 to 6548)
  AUTHORS   Ishibashi,K., Kanno,E., Itoh,T. and Fukuda,M.
  TITLE     Identification and characterization of a novel Tre-2/Bub2/Cdc16
            (TBC) protein that possesses Rab3A-GAP activity
  JOURNAL   Genes Cells 14 (1), 41-52 (2009)
   PUBMED   19077034
REFERENCE   8  (bases 1 to 6548)
  AUTHORS   Yoshimura,S., Egerer,J., Fuchs,E., Haas,A.K. and Barr,F.A.
  TITLE     Functional dissection of Rab GTPases involved in primary cilium
            formation
  JOURNAL   J Cell Biol 178 (3), 363-369 (2007)
   PUBMED   17646400
REFERENCE   9  (bases 1 to 6548)
  AUTHORS   Lim,J., Hao,T., Shaw,C., Patel,A.J., Szabo,G., Rual,J.F.,
            Fisk,C.J., Li,N., Smolyar,A., Hill,D.E., Barabasi,A.L., Vidal,M.
            and Zoghbi,H.Y.
  TITLE     A protein-protein interaction network for human inherited ataxias
            and disorders of Purkinje cell degeneration
  JOURNAL   Cell 125 (4), 801-814 (2006)
   PUBMED   16713569
REFERENCE   10 (bases 1 to 6548)
  AUTHORS   Brill,L.M., Salomon,A.R., Ficarro,S.B., Mukherji,M.,
            Stettler-Gill,M. and Peters,E.C.
  TITLE     Robust phosphoproteomic profiling of tyrosine phosphorylation sites
            from human T cells using immobilized metal affinity chromatography
            and tandem mass spectrometry
  JOURNAL   Anal Chem 76 (10), 2763-2772 (2004)
   PUBMED   15144186
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104451.2, AC144531.2, AC090960.3 and AC090644.2.
            
            On Aug 13, 2020 this sequence version replaced NM_001349084.1.
            
            Transcript Variant: This variant (14), as well as variants 12, 13,
            15, and 16, encodes isoform d.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.153790.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-151               AC104451.2         117130-117280       c
            152-216             AC144531.2         124073-124137       c
            217-334             AC144531.2         122872-122989       c
            335-466             AC144531.2         8698-8829           c
            467-575             AC090960.3         53719-53827
            576-665             AC090960.3         55284-55373
            666-740             AC090960.3         55477-55551
            741-808             AC090960.3         56997-57064
            809-911             AC090960.3         76230-76332
            912-1000            AC090960.3         83632-83720
            1001-1051           AC090960.3         85566-85616
            1052-1121           AC090960.3         85705-85774
            1122-1294           AC090960.3         87998-88170
            1295-1437           AC090960.3         152111-152253
            1438-1544           AC090960.3         168244-168350
            1545-1630           AC090644.2         169745-169830       c
            1631-1887           AC090644.2         149402-149658       c
            1888-1953           AC090644.2         144924-144989       c
            1954-2117           AC090644.2         125446-125609       c
            2118-2217           AC090644.2         96348-96447         c
            2218-2297           AC090644.2         78988-79067         c
            2298-2459           AC090644.2         78006-78167         c
            2460-6548           AC090644.2         68407-72495         c
FEATURES             Location/Qualifiers
     source          1..6548
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p24.3"
     gene            1..6548
                     /gene="TBC1D5"
                     /note="TBC1 domain family member 5"
                     /db_xref="GeneID:9779"
                     /db_xref="HGNC:HGNC:19166"
                     /db_xref="MIM:615740"
     exon            1..151
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            152..216
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            217..334
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            335..466
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            467..575
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            576..665
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            666..740
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     CDS             708..2753
                     /gene="TBC1D5"
                     /note="isoform d is encoded by transcript variant 14"
                     /codon_start=1
                     /product="TBC1 domain family member 5 isoform d"
                     /protein_id="NP_001336013.1"
                     /db_xref="GeneID:9779"
                     /db_xref="HGNC:HGNC:19166"
                     /db_xref="MIM:615740"
                     /translation="MINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQE
                     NVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMK
                     TVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIA
                     IVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDA
                     LFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLR
                     DPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLIS
                     PAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLN
                     KGDVVTGSDAQVSVPVQTLTDLQGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDS
                     FFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQD
                     VILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQLEAEENEQITIADNHYCSSGQ
                     GQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISKDDDGSSARGSFSGQAQPL
                     RTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDDSSKDSGFTIVSPLDI"
     exon            741..808
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            809..911
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1000
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1051
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1121
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1294
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1437
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1544
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1630
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1887
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1888..1953
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            1954..2117
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            2118..2217
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            2218..2297
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            2298..2459
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     exon            2460..6548
                     /gene="TBC1D5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6529..6534
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TBC1D5"
                     /note="hexamer: AATAAA"
     polyA_site      6548
                     /gene="TBC1D5"
                     /note="major polyA site"
ORIGIN      
        1 gccaccccct cccgccctgt tctctttcag gtcgggccgg gcccggccgc ttccgcgagc
       61 gccctgcaga ctgagggaga gagagagaaa gaggagggga ggaggaggag gattcaggga
      121 ataggagctg gggagccctt ctgcgccaca gtgatatcag tatcaagata aaagtttgga
      181 atgggagaaa aattctcaaa gcctgaaaga aaatctgaga tgcttggagt gtaaagatcc
      241 catggtcaca taaatccgga aagcactgaa tactttgttt cccataagag aatcccatta
      301 tatgttgatg tattaaaaga cctgagaacc tggtgtagtt acttttggtg acgctgtcca
      361 gttcccacaa tgtatcattc cttatctgaa actagacatc ctctgcagcc agaagaacaa
      421 gaagtaggca ttgacccctt gtccagttac tctaacaagt ctggaggaaa gaatgggaag
      481 aactatttgt aaacaacaat tacttggcaa caataaggca gaaggggatt aatgggcagc
      541 tgagaagcag caggttccgc agcatttgct ggaagctatt tctttgtgtt cttcctcaag
      601 acaaaagtca atggataagt agaattgaag aattaagagc atggtatagc aacattaaag
      661 aaatacatat taccaacccg aggaaggttg ttggccaaca agatttgatg atcaataatc
      721 ctctttcaca ggatgaaggg agtctttgga acaaattctt ccaagataaa gaacttcgat
      781 caatgattga acaagatgtc aaaagaacgt ttcctgaaat gcagtttttc cagcaagaaa
      841 atgtgagaaa aattcttaca gatgttcttt tctgttatgc cagagaaaac gagcagttgc
      901 tttataaaca gggcatgcac gaactgttag cacctatagt ctttgtcctt cactgtgacc
      961 accaagcttt tctacatgcc agtgagtctg cacagcccag tgaggaaatg aaaactgtct
     1021 tgaaccctga gtatctggaa catgatgcct atgcagtgtt ctcacaactt atggaaactg
     1081 ctgaaccttg gttttcaact tttgagcatg atggtcagaa ggggaaagaa acactgatga
     1141 ctcccattcc ctttgctaga ccacaagatt tagggccaac aattgctatt gttactaaag
     1201 tcaaccagat ccaggatcat ctactgaaga agcatgatat tgagctttac atgcacttga
     1261 acagactaga aattgcacca cagatatatg ggttaaggtg ggtgcggctg ctatttggac
     1321 gagagttccc cctgcaggac cttctggtgg tctgggatgc cttgtttgca gacggcctca
     1381 gcctgggttt agtagattat atcttcgtag ccatgttact ttacatccga gatgctttga
     1441 tctctagtaa ctaccagacc tgtctcggcc ttctgatgca ttacccattc atcggggatg
     1501 tacactcact gattcttaag gctctgttcc ttagagatcc aaagagaaat ccaagaccag
     1561 tgacttatca attccatcca aatttagatt attacaaagc acgaggagca gacctcatga
     1621 ataaaagccg gaccaatgcc aaaggtgctc ccctgaatat aaataaggtc tctaatagcc
     1681 tgattaattt tggaagaaag ttgatttccc cagcaatggc tccaggcagt gcaggtggcc
     1741 ctgtacctgg aggcaacagc agtagctcct cctctgttgt aattcctacc aggacctcag
     1801 cagaggcccc aagccatcac ttgcaacagc aacagcagca gcagaggctg atgaaatcag
     1861 aaagcatgcc tgtgcaattg aacaaaggcg atgtagttac aggaagcgat gctcaggttt
     1921 ctgttcctgt ccagactcta actgacctcc aagggctaag ttctaaaaac atcagttcat
     1981 ctccaagcgt tgagagtttg cctggaggaa gagaattcac tggctctcca ccttcatctg
     2041 ctactaaaaa agattccttt tttagcaaca tctcacgttc tcgctcacac agcaaaacta
     2101 tgggcagaaa agaatctgaa gaagaattag aagcccaaat ttccttcctt caagggcagt
     2161 tgaatgacct ggatgccatg tgcaaatact gtgcaaaggt gatggacact catcttgtaa
     2221 atattcaaga tgtgatatta caagaaaatt tggaaaaaga agatcaaatt ctggtttccc
     2281 tggcaggatt aaaacagatc aaagacattc taaaaggttc cctgcgtttt aaccagagcc
     2341 agctagaggc cgaagagaac gaacagatca ccattgcgga caaccactac tgctccagcg
     2401 gccagggcca gggccgaggc caaggccaga gcgttcaaat gtcaggggcc attaaacagg
     2461 cctcttcaga aacgccaggg tgcactgata gagggaattc cgatgacttc atcctgattt
     2521 ccaaagatga tgatgggagc agtgccaggg gctccttctc cggccaggcc cagcctcttc
     2581 gcaccctcag aagcacctct gggaaaagcc aggccccagt ctgctcccca ctggtgttct
     2641 cagatccact gatgggccca gcctcagctt cctccagcaa ccccagctcc agtcctgatg
     2701 acgacagcag caaggactct ggcttcacca ttgtgagtcc cctggacatc tgaccacagt
     2761 gcccagtcct gccccacagg gatctagcca cccttcagtg gccccaaggc cagactgagg
     2821 ctcatccagt ggagaacctt cttaaaccac tgcttccttc ccggcatgca ttttgcattg
     2881 gtccagccct ttgaaacccc ttagagagaa gcatatatgg ccacaaagca cagaggctta
     2941 ggtttgccac atgcagacag ggctttctgg gcccttacct aatccccacc cgactcttgc
     3001 tctgagttag agctgagtta cgtacccagt atcacactca cagttagaaa agaccgaatc
     3061 acaatttaga atcacttttc ctctgtcccc ttctccccag ctaagaatgt gtggcacctc
     3121 catcagttat acttagaagg agcagaaata gttattttcg tatcttctat ccctcaaagc
     3181 atcagacatg ggaaaattgg tttataccaa gaaagcttcc tctgtggaaa tctgtctcag
     3241 cctactttat tcctgcattg ggaagccata tcgcagagct aaatgcaata gaatgaacca
     3301 gaactagtgg attccagggc tgggggaaaa aaaaaaagaa aaaacctcat tactgacctc
     3361 tcaaagttat aaggatctct gcaaacagga tctaagctta ggaataatat ttaggtgtga
     3421 tatagtgtta gatttttttg atgtattaaa gaatgcatct ccaatcctta ggccatatca
     3481 actttggcca tcaatatctc tccttaaaca attatatttc accttttaga atctttcata
     3541 gccagaaaac aagattactg taagccagtt ttagctgcac tgatttcaaa agatataaga
     3601 atattactat ccttcaaatg gaaaatgcga ccttgacttt atgggataaa catctttcag
     3661 acagtcagtt ttctagtcag gtttctctgg tttcagagct gtatatacct gtcaactgag
     3721 gaataaaggg aaaaacccaa gttcattccc acccaaagtc agaatccctc attggcctta
     3781 aggtagcagt cataagacag agaattggac ctagagtccc ttctgtgggg aataaggata
     3841 cctagagaac attccacatg ccaagaggat gcaggatttc tacacaaccc cttcccttct
     3901 tggaagtcaa gtgtaggtac tgcagggcct gtgctcagct gtgaaccccg tatcctgggc
     3961 cccactgccg ggaccgggtc tgacatgcca gtgccttcct gggctgagca cagattagag
     4021 actctccccc ttgtcagtca gcaccttagg aaaccatgat gggcacagag catcacatga
     4081 gctgtttctc tccttaaaga agatccctgg aaaggatgct tttcctctcc tttgcctgcg
     4141 caggaattct aacaggagtg ggtgaggatg gcagagggac acagtgcctg tctcgcctcc
     4201 atcagggaga gcagccatgc cagggatgac tagctctttg agcctgtcct cagaggatgg
     4261 cgaggcagcc gggcagtgga ggccttcatg gtaacaaatg aaagctcagt atagaggaac
     4321 agacactgtt tacgtccctc ccactgctaa ccttatatat ctctatagac aaatgtgata
     4381 atgacatgat ttcccacctg ccctccaaga aaatggtgac tcactctcaa gtcagctact
     4441 gtagagaggg ttctaattgg ttctgcaatt tgctcttaaa ctctagcagg gaactctcct
     4501 cttaccacat cagcatgtaa ggtgaataat aactggtttt gccagacagc aggttgtctg
     4561 accttcaacc actgggcaat tgcctggcag atgcacacag tagctccctg gcttctggct
     4621 ctgagtgttc ctctcagcac ctctgagtaa gctgctgcca agcacatatc cctatgacaa
     4681 cactttgtaa aagccgcggg gcccccatac agcgagtgac cttgcaactg tgcagggttg
     4741 ccattggtca ctttctcacc ttgggaaggt gtcagtgttt tcagttctaa ggtaagaggt
     4801 gtagagctgt tcccaccagg gctctgggac agactggaaa ggaccacaga cctggccatc
     4861 cctgggcagc agggccagtg tcacctgctg acctctagta tttcctttgc cctagagcta
     4921 gagtcatgat agctgagggt cactcgccct gcaagagtca ctaggcaccc accatgccaa
     4981 taaggctctc cgctggctcc ctgcagttgg ctgggtgttt aatagtcact gaaaactccc
     5041 agccctgctg cacactagag gcaggtcctc tcggtcctct ccatcctgtg cttctgtggc
     5101 ccccagcaag ctcaccacct ccttggagga gagagacata caaggacagt gggtcatggg
     5161 tagtaccagc ctcaaattcc cacaggctca tactcagaca attgtattac tgccttatgt
     5221 tttttaagtg tttttttaaa ttcttcatag ttgagtatta tttgcaattt tattagttac
     5281 agtgctatta aagaatatgt gctccttttt attatattat cagatactta tgtttaattg
     5341 tacatttttt aaatcctgaa tatattgtgt tttgttaaca aatgtaatca gtggaaccct
     5401 tcttacgttt tgattattag cagttaaata cattttgtat acatgaagct tagattaatt
     5461 cccatcatca tcatctcctg tttttatatg tgtccctatg tgtttcatgc attcctcttt
     5521 gatcagattg gaatttgagt taaaatttag ctttgtacat tacgtgtgag agttacagac
     5581 tagcaagtct aattactttg ccttaccttg agtgtatgcc acagggtcag ataacacatt
     5641 aaacatttag ttacactgga ttactcttcc aaagctgacc tcctgctaat gttcagaggt
     5701 aactgcaatc cggaaagaaa taatatcact gcagaaagaa tgtgactcta aaaataaacc
     5761 aggacctccc tgtgatttgc cttgcctgca gatgaccagt tgactcttgt gctgtcagcc
     5821 ctggggttgc taaggaagct gcttcaggga gttgggggtt agttgcccgc tctcaacagg
     5881 aatgcctcct ctactttgtc agagatgctg aacaaatatc aaactctgtg gcagtcatgc
     5941 tggcctccta agaataacct gtgagtcaga gttgatgcac attatttttg tttttatttt
     6001 atttttttaa ggaactgctc caagggttca ttatagaaca ggagtgtgta cggaggactt
     6061 aggtccccac atagagtggc cgttctgtgg cggctccaac caattccatc cctcctttcc
     6121 tgcggacaca cacctggccc ctggcccctg ccctgtgtgt ctggaggagg ggcactgggg
     6181 aggctgtgga gcagagagaa gaggccggat acattgagga tggcacctgg caagccaggc
     6241 ttccttctca aaggccagac tgctttctca gtgttactta ctaaagctct ctttttatac
     6301 tgttaaaaag atatataaag ttcgtataaa caggcttgag accactttga tgtaaaagct
     6361 gtcatagtag tttttctcac agtggcacaa ttcatttgat tgatggaata ttcagtgacg
     6421 ccatgtatgc cctatcgctt ttttctcatc catctttatg ctataactca tactgattta
     6481 agaaatgatt tctccttttg gcaaagcgac cccattcaat atggttataa taaaagacta
     6541 atgtcaaa
//
