LOCUS       NM_001369500            3505 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens TBC1 domain family member 3L (TBC1D3L), transcript
            variant 3, mRNA.
ACCESSION   NM_001369500
VERSION     NM_001369500.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3505)
  AUTHORS   Hodzic,D., Kong,C., Wainszelbaum,M.J., Charron,A.J., Su,X. and
            Stahl,P.D.
  TITLE     TBC1D3, a hominoid oncoprotein, is encoded by a cluster of
            paralogues located on chromosome 17q12
  JOURNAL   Genomics 88 (6), 731-736 (2006)
   PUBMED   16863688
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC243569.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.87423.1,
                                           SRR1660805.243629.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000612727.5/ ENSP00000481508.1
            RefSeq Select criteria :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1612              AC243569.3         236626-238237       c
            1613-1698           AC243569.3         236378-236463       c
            1699-1738           AC243569.3         235055-235094       c
            1739-1819           AC243569.3         234492-234572       c
            1820-1927           AC243569.3         233941-234048       c
            1928-2037           AC243569.3         233502-233611       c
            2038-2086           AC243569.3         232205-232253       c
            2087-2207           AC243569.3         231541-231661       c
            2208-2302           AC243569.3         230733-230827       c
            2303-2368           AC243569.3         230283-230348       c
            2369-2468           AC243569.3         229720-229819       c
            2469-2621           AC243569.3         229197-229349       c
            2622-3505           AC243569.3         227332-228215       c
FEATURES             Location/Qualifiers
     source          1..3505
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q12"
     gene            1..3505
                     /gene="TBC1D3L"
                     /note="TBC1 domain family member 3L"
                     /db_xref="GeneID:101060376"
                     /db_xref="HGNC:HGNC:51246"
     exon            1..1612
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     CDS             1541..3190
                     /gene="TBC1D3L"
                     /note="isoform 2 is encoded by transcript variant 3"
                     /codon_start=1
                     /product="TBC1 domain family member 3L isoform 2"
                     /protein_id="NP_001356429.1"
                     /db_xref="CCDS:CCDS74043.1"
                     /db_xref="GeneID:101060376"
                     /db_xref="HGNC:HGNC:51246"
                     /translation="MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNN
                     NVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGM
                     PMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFR
                     DRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASER
                     HSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDG
                     ISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWAR
                     DEDTVLKHLRASMKKLTRKQGDLQPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPG
                     PPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFL
                     QWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAA
                     PSTDSDQGTPFRARDEQPCAPTSGPCLCGLHLESSQFPPGF"
     exon            1613..1698
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1699..1738
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1739..1819
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1927
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2037
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            2038..2086
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2207
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            2208..2302
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            2303..2368
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            2369..2468
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            2469..2621
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
     exon            2622..3505
                     /gene="TBC1D3L"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtggtctac agcagttaca cacaggcagt ggtatctgtg agcagctctg tggactcaaa
       61 ggttttctcc ctgagaggca cgacccaggc cagctgattc atcagaatca ggtgagcgtg
      121 acctgctctc ttccctccag gcggacttgg gggcagtggc tacggtgcgg gcggtgttgg
      181 cctctgtggg gcagctaccg aggagggtca tccctgagca ctcaccaggc gcccgttcta
      241 cactgcccgt gtagacgatt ggctctttcg tctccatggt ggcttcgtag agtgggtgct
      301 gttcccaaat gtccccattc gacagatgag acgtctgggg tcagagaggc agtaaccggc
      361 ctgggaatcc ggacatgacc ctgagttttg ctctcagccc tgccgtgtgc tgtgctggaa
      421 ttcaggcctg aaccctgtga cctccctgcc ctagatccca aatctgccca ggtttcccat
      481 cccgatgggg cagagcctgg tcctggcaga gccactggta tagagccact ggtacagatc
      541 cactgacggt cctcagaaca cctctgtgcc ctaagctggg tcctgatggt cgctgtgggc
      601 cccactgaac acacatggtc ccttgtccgg gggagcctgc tgcccttggg cagctgtgga
      661 aaatgaagga gccctggagg gctggctgag gggagactat cttcccttgt gttcaaaggg
      721 gtccgggcac tagggttctc cccaggtatt tcttgctctg cgtggtcctc ttgaggcctc
      781 gccctccttt tgcctcgagt attcccagga gggacggtcc atccagctgt tctccaggac
      841 caaggaccca ctgttcttcc tcagtgaccc aggaaaatga agcctcctcc tgttgggacg
      901 gctcagaatg gtggactcca cagtccctcc gcgagagacg tggtttccat gcgtacaata
      961 gatctttctc atcccccaaa cccaacaccc tcctgctcaa caggcgttat tcctaaagtg
     1021 gcttcactgt tcagactgaa gagccacggt agccaaagtg atgagcggag tagaaccgag
     1081 cagtcgggag agatcttgtt ccctgtagga aactgggcat cgctgaggcc ctgagcatcc
     1141 caggaggccg attgcacaga gacctctggt cgctgacccc agtctgcctc cacatccctg
     1201 gaatagccca tcatgggccc ttcacccttg gcaggtggaa accattcaac ctgctggggc
     1261 cggtgtgtcc ccatttcatg gcattggggg acaacaggat tctctgtcta ggtcccactg
     1321 tactcaagtc cttgggaaga tgcccacccc tgcttgggac ttgagactcc agagactgga
     1381 gcagctgtgg gccactgggt ctggcccctt tttccctggg ggcggcggtg gaatgggggt
     1441 tacgcagcca gccagcatct gggagcccgg cgagagcggt tcaggtgttc tccgaagccg
     1501 ccgcgtacgg tgtgaccttt agacaattct gtctcacagg atggacgtgg tagaggtcgc
     1561 gggcagttgg tgggcacaag agcgagagga catcattatg aaatacgaaa agggacaccg
     1621 agctgggctg ccagaggaca aggggcctaa gccttttcga agctacaaca acaacgtcga
     1681 tcatttgggg attgtacatg agacggagct gcctcctctg actgcgcggg aggcgaagca
     1741 aattcggcgg gagatcagcc gaaagagcaa gtgggtggat atgctgggag actgggagaa
     1801 atacaaaagc agcagaaagc tcatagatcg agcgtacaag ggaatgccca tgaacatccg
     1861 gggcccgatg tggtcagtcc tcctgaacac tgaggaaatg aagttgaaaa accccggaag
     1921 ataccagatc atgaaggaga agggcaagag gtcatctgag cacatccagc gcatcgaccg
     1981 ggacgtaagc gggacattaa ggaagcatat attcttcagg gatcgatacg gaaccaagca
     2041 gcgggaacta ctccacatcc tcctggcata tgaggagtat aacccggagg tgggctactg
     2101 cagggacctg agccacatcg ccgccttgtt cctcctctat cttcctgagg aggatgcatt
     2161 ctgggcactg gtgcagctgc tggccagtga gaggcactcc ctgcagggat ttcacagccc
     2221 aaatggcggg accgtccagg ggctccaaga ccaacaggag catgtggtag ccacgtcaca
     2281 acccaagacc atggggcatc aggacaagaa agatctatgt gggcagtgtt ccccgttagg
     2341 ctgcctcatc cggatattga ttgacgggat ctctctcggg ctcaccctgc gcctgtggga
     2401 cgtgtatctg gtagaaggcg aacaggcgtt gatgccgata acaagaatcg cctttaaggt
     2461 tcagcagaag cgcctcacga agacgtccag gtgtggcccg tgggcacgtt tttgcaaccg
     2521 gttcgttgat acctgggcca gggatgagga cactgtgctc aagcatctta gggcctctat
     2581 gaagaaacta acaagaaagc agggggacct gcaaccccca gccaaacccg agcaagggtc
     2641 gtcggcatcc aggcctgtgc cggcttcacg tggcgggaag accctctgca agggggacag
     2701 gcaggcccct ccaggcccac cagcccggtt cccgcggccc atttggtcag cttccccgcc
     2761 acgggcacct cgttcttcca caccctgtcc tggtggggct gtccgggaag acacctaccc
     2821 tgtgggcact cagggtgtgc ccagcccggc cctggctcag ggaggacctc agggttcctg
     2881 gagattcctg cagtggaact ccatgccccg cctcccaacg gacctggacg tagagggccc
     2941 ttggttccgc cattatgatt tcagacagag ctgctgggtc cgtgccatat cccaggagga
     3001 ccagctggcc ccctgctggc aggctgaaca ccctgcggag cgggtgagat cggctttcgc
     3061 tgcacccagc actgattccg accagggcac ccccttcaga gctagggacg aacagccgtg
     3121 tgctcccacc tcagggcctt gcctctgcgg cctccacttg gaaagttctc agttccctcc
     3181 aggcttctag aagcatctgg gccagggctc atggctggat aatttcccta ggcttaacaa
     3241 cccaagcaag cttcgcatcc tcgttttatt tttggttaaa cttatgaaaa tgtattaaga
     3301 aagagtgcag ctcgagagag attcagagat ggaacacacc agaccccaga tcacaaagcc
     3361 aaccatgccc agcccctccc agcaccccca gccccacgac catcgttctg aattctgacg
     3421 acaccgtgag cctgcctttg tacttcaaac tcatggaagg ataaccacct tcatgttttg
     3481 aaataaatgt ttcctgttga aatga
//
