LOCUS       NM_001291463            2122 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens TBC1 domain family member 3I (TBC1D3I), mRNA.
ACCESSION   NM_001291463 XM_006722225 XM_006725370 XM_006725576 XM_006726721
VERSION     NM_001291463.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2122)
  AUTHORS   Hodzic,D., Kong,C., Wainszelbaum,M.J., Charron,A.J., Su,X. and
            Stahl,P.D.
  TITLE     TBC1D3, a hominoid oncoprotein, is encoded by a cluster of
            paralogues located on chromosome 17q12
  JOURNAL   Genomics 88 (6), 731-736 (2006)
   PUBMED   16863688
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC243829.3.
            
            On Jul 22, 2021 this sequence version replaced NM_001291463.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000621034.2/ ENSP00000481258.1
            RefSeq Select criteria    :: based on manual assertion
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               AC243829.3         231650-231805       c
            157-229             AC243829.3         230149-230221       c
            230-315             AC243829.3         229901-229986       c
            316-355             AC243829.3         228578-228617       c
            356-436             AC243829.3         228015-228095       c
            437-544             AC243829.3         227464-227571       c
            545-654             AC243829.3         227025-227134       c
            655-703             AC243829.3         225728-225776       c
            704-824             AC243829.3         225064-225184       c
            825-919             AC243829.3         224256-224350       c
            920-985             AC243829.3         223806-223871       c
            986-1085            AC243829.3         223243-223342       c
            1086-1238           AC243829.3         222720-222872       c
            1239-2122           AC243829.3         220874-221757       c
FEATURES             Location/Qualifiers
     source          1..2122
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q12"
     gene            1..2122
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /note="TBC1 domain family member 3I"
                     /db_xref="GeneID:102724862"
                     /db_xref="HGNC:HGNC:32709"
     exon            1..156
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            157..229
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..1807
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /note="TBC1 domain family member-like; TBC1 domain family
                     member 3; Prostate cancer gene 17 protein; Protein
                     TRE17-alpha; Rab GTPase-activating protein PRC17"
                     /codon_start=1
                     /product="TBC1 domain family member 3I"
                     /protein_id="NP_001278392.1"
                     /db_xref="CCDS:CCDS74039.1"
                     /db_xref="GeneID:102724862"
                     /db_xref="HGNC:HGNC:32709"
                     /translation="MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNN
                     NVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGM
                     PMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFR
                     DRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASER
                     HSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDG
                     ISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWAR
                     DEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPG
                     PPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFL
                     QWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAA
                     PSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF"
     exon            230..315
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            316..355
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            356..436
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            437..544
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            545..654
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            655..703
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            704..824
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            825..919
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            920..985
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1085
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1238
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..2122
                     /gene="TBC1D3I"
                     /gene_synonym="PRC17; TBC1D3; TBC1D3A"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatgtcact ggtgcttagc acctatctgc tctctggtct gcctcagtgg tctacagcag
       61 ttacacacag gcagtggtat ctgtgagcag ctctgtggac tcaaaggttt tctccctgag
      121 aggcatgacc caggccagct gattcatcag aatcaggatg gacgtggtag aggtcgcggg
      181 cagttggtgg gcacaagagc gagaggacat cattatgaaa tacgaaaagg gacaccgagc
      241 tgggctgcca gaggacaagg ggcctaagcc ttttcgaagc tacaacaaca acgtcgatca
      301 tttggggatt gtacatgaga cggagctgcc tcctctgact gcgcgggagg cgaagcaaat
      361 tcggcgggag atcagccgaa agagcaagtg ggtggatatg ctgggagact gggagaaata
      421 caaaagcagc agaaagctca tagatcgagc gtacaaggga atgcccatga acatccgggg
      481 cccgatgtgg tcagtcctcc tgaacactga ggaaatgaag atgaaaaacc ccggaagata
      541 ccagatcatg aaggagaagg gcaagaggtc atctgagcac atccagcgca tcgaccggga
      601 cgtaagcggg acattaagga agcatatatt cttcagggat cgatacggaa ccaagcagcg
      661 ggaactactc cacatcctcc tggcatatga ggagtataac ccggaggtgg gctactgcag
      721 ggacctgagc cacatcgccg ccttgttcct cctctatctt cctgaggagg atgcattctg
      781 ggcactggtg cagctgctgg ccagtgagag gcactccctg cagggatttc acagcccaaa
      841 tggcgggacc gtccaggggc tccaagacca acaggagcat gtggtagcca cgtcacaacc
      901 caagaccatg gggcatcagg acaagaaaga tctatgtggg cagtgttccc cgttaggctg
      961 cctcatccgg atattgattg acgggatctc tctcgggctc accctgcgcc tgtgggacgt
     1021 gtatctggta gaaggcgaac aggcgttgat gccgataaca agaatcgcct ttaaggttca
     1081 gcagaagcgc ctcacgaaga cgtccaggtg tggcccgtgg gcacgttttt gcaaccggtt
     1141 cgttgatacc tgggccaggg atgaggacac tgtgctcaag catcttaggg cctctatgaa
     1201 gaaactaaca agaaagcagg gggacctgcc acccccagcc aaacccgagc aagggtcgtc
     1261 ggcatccagg cctgtgccgg cttcacgtgg cgggaagacc ctctgcaagg gggacaggca
     1321 ggcccctcca ggcccaccag cccggttccc gcggcccatt tggtcagctt ccccgccacg
     1381 ggcacctcgt tcttccacac cctgtcctgg tggggctgtc cgggaagaca cctaccctgt
     1441 gggcactcag ggtgtgccca gcccggccct ggctcaggga ggacctcagg gttcctggag
     1501 attcctgcag tggaactcca tgccccgcct cccaacggac ctggacgtag agggcccttg
     1561 gttccgccat tatgatttca gacagagctg ctgggtccgt gccatatccc aggaggacca
     1621 gctggccccc tgctggcagg ctgaacaccc tgcggagcgg gtgagatcgg ctttcgctgc
     1681 acccagcact gattccgacc agggcacccc cttcagagct agggacgaac agcagtgtgc
     1741 tcccacctca gggccttgcc tctgcggcct ccacttggaa agttctcagt tccctccagg
     1801 cttctagaag catctgggcc agggctcatg gctggataat ttccctaggc ttaacaaccc
     1861 aagcaagctt cgcgtcctcg ttttattttt ggttaaactt atgaaaatgt attaagaaag
     1921 agtgcagctc gagagagatt cagagatgga acacaccaga ccccagatca caaagccaac
     1981 catgcccagc ccctcccagc acccccagcc ccacgaccat cgttctgaat tctgacgaca
     2041 ccgtgagcct gcctttgtac ttcaaactca tggaaggata accaccttca tgttttgaaa
     2101 taaatgtttc ctgttgaaat ga
//
