LOCUS       NM_001123392            2077 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens TBC1 domain family member 3H (TBC1D3H), mRNA.
ACCESSION   NM_001123392 NM_001159332 XM_001134202
VERSION     NM_001123392.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2077)
  AUTHORS   Hodzic,D., Kong,C., Wainszelbaum,M.J., Charron,A.J., Su,X. and
            Stahl,P.D.
  TITLE     TBC1D3, a hominoid oncoprotein, is encoded by a cluster of
            paralogues located on chromosome 17q12
  JOURNAL   Genomics 88 (6), 731-736 (2006)
   PUBMED   16863688
REFERENCE   2  (bases 1 to 2077)
  AUTHORS   Zody,M.C., Garber,M., Adams,D.J., Sharpe,T., Harrow,J.,
            Lupski,J.R., Nicholson,C., Searle,S.M., Wilming,L., Young,S.K.,
            Abouelleil,A., Allen,N.R., Bi,W., Bloom,T., Borowsky,M.L.,
            Bugalter,B.E., Butler,J., Chang,J.L., Chen,C.K., Cook,A., Corum,B.,
            Cuomo,C.A., de Jong,P.J., DeCaprio,D., Dewar,K., FitzGerald,M.,
            Gilbert,J., Gibson,R., Gnerre,S., Goldstein,S., Grafham,D.V.,
            Grocock,R., Hafez,N., Hagopian,D.S., Hart,E., Norman,C.H.,
            Humphray,S., Jaffe,D.B., Jones,M., Kamal,M., Khodiyar,V.K.,
            LaButti,K., Laird,G., Lehoczky,J., Liu,X., Lokyitsang,T.,
            Loveland,J., Lui,A., Macdonald,P., Major,J.E., Matthews,L.,
            Mauceli,E., McCarroll,S.A., Mihalev,A.H., Mudge,J., Nguyen,C.,
            Nicol,R., O'Leary,S.B., Osoegawa,K., Schwartz,D.C., Shaw-Smith,C.,
            Stankiewicz,P., Steward,C., Swarbreck,D., Venkataraman,V.,
            Whittaker,C.A., Yang,X., Zimmer,A.R., Bradley,A., Hubbard,T.,
            Birren,B.W., Rogers,J., Lander,E.S. and Nusbaum,C.
  TITLE     DNA sequence of human chromosome 17 and analysis of rearrangement
            in the human lineage
  JOURNAL   Nature 440 (7087), 1045-1049 (2006)
   PUBMED   16625196
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC233698.3.
            
            On Feb 24, 2021 this sequence version replaced NM_001123392.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000610350.4/ ENSP00000482630.1
            RefSeq Select criteria :: based on manual assertion
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-111               AC233698.3         177708-177818
            112-184             AC233698.3         179247-179319
            185-270             AC233698.3         179482-179567
            271-310             AC233698.3         180850-180889
            311-391             AC233698.3         181372-181452
            392-499             AC233698.3         181896-182003
            500-609             AC233698.3         182333-182442
            610-658             AC233698.3         183691-183739
            659-779             AC233698.3         184283-184403
            780-874             AC233698.3         185117-185211
            875-940             AC233698.3         185596-185661
            941-1040            AC233698.3         186125-186224
            1041-1193           AC233698.3         186595-186747
            1194-2077           AC233698.3         187729-188612
FEATURES             Location/Qualifiers
     source          1..2077
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q12"
     gene            1..2077
                     /gene="TBC1D3H"
                     /note="TBC1 domain family member 3H"
                     /db_xref="GeneID:729877"
                     /db_xref="HGNC:HGNC:30708"
                     /db_xref="MIM:610811"
     exon            1..111
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            112..184
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     CDS             113..1762
                     /gene="TBC1D3H"
                     /note="TBC1 domain family member 3-like"
                     /codon_start=1
                     /product="TBC1 domain family member 3H"
                     /protein_id="NP_001116864.3"
                     /db_xref="CCDS:CCDS45653.1"
                     /db_xref="GeneID:729877"
                     /db_xref="HGNC:HGNC:30708"
                     /db_xref="MIM:610811"
                     /translation="MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNN
                     NVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGM
                     PMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFR
                     DRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASER
                     HSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDG
                     ISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWAR
                     DEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPG
                     PPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFL
                     QWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAA
                     PSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF"
     exon            185..270
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            271..310
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            311..391
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            392..499
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            500..609
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            610..658
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            659..779
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            780..874
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            875..940
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1040
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1193
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
     exon            1194..2077
                     /gene="TBC1D3H"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtggtctac agcagttaca cacaggcagt ggtatctgtg agcagctctg tggactcaaa
       61 ggttttctcc ctgagaggca tgacccaggc cagctgattc atcagaatca ggatggacgt
      121 ggtagaggtc gcgggcagtt ggtgggcaca agagcgagag gacatcatta tgaaatacga
      181 aaagggacac cgagctgggc tgccagagga caaggggcct aagccttttc gaagctacaa
      241 caacaacgtc gatcatttgg ggattgtaca tgagacggag ctgcctcctc tgactgcgcg
      301 ggaggcgaag caaattcggc gggagatcag ccgaaagagc aagtgggtgg atatgctggg
      361 agactgggag aaatacaaaa gcagcagaaa gctcatagat cgagcgtaca agggaatgcc
      421 catgaacatc cggggcccga tgtggtcagt cctcctgaac actgaggaaa tgaagttgaa
      481 aaaccccgga agataccaga tcatgaagga gaagggcaag aggtcatctg agcacatcca
      541 gcgcatcgac cgggacataa gcgggacatt aaggaagcat atgttcttca gggatcgata
      601 cggaaccaag cagcgggaac tactccacat cctcctggca tatgaggagt ataacccgga
      661 ggtgggctac tgcagggacc tgagccacat cgccgccttg ttcctcctct atcttcctga
      721 ggaggatgca ttctgggcac tggtgcagct gctggccagt gagaggcact ccctgcaggg
      781 atttcacagc ccaaatggcg ggaccgtcca ggggctccaa gaccaacagg agcatgtggt
      841 agccacgtca caacccaaga ccatggggca tcaggacaag aaagatctat gtgggcagtg
      901 ttccccgtta ggctgcctca tccggatatt gattgacggg atctctctcg ggctcaccct
      961 gcgcctgtgg gacgtgtatc tggtagaagg cgaacaggcg ttgatgccga taacaagaat
     1021 cgcctttaag gttcagcaga agcgcctcac gaagacgtcc aggtgtggcc cgtgggcacg
     1081 tttttgcaac cggttcgttg atacctgggc cagggatgag gacactgtgc tcaagcatct
     1141 tagggcctct atgaagaaac taacaagaaa gcagggggac ctgccacccc cagccaaacc
     1201 cgagcaaggg tcgtcggcat ccaggcctgt gccggcttca cgtggcggga agaccctctg
     1261 caagggggac aggcaggccc ctccaggccc accagcccgg ttcccgcggc ccatttggtc
     1321 agcttccccg ccacgggcac ctcgttcttc cacaccctgt cctggtgggg ctgtccggga
     1381 agacacctac cctgtgggca ctcagggtgt gcccagcccg gccctggctc agggaggacc
     1441 tcagggttcc tggagattcc tgcagtggaa ctccatgccc cgcctcccaa cggacctgga
     1501 cgtagagggc ccttggttcc gccattatga tttcagacag agctgctggg tccgtgccat
     1561 atcccaggag gaccagctgg ccccctgctg gcaggctgaa caccctgcgg agcgggtgag
     1621 atcggctttc gctgcaccca gcactgattc cgaccagggc acccccttca gagctaggga
     1681 cgaacagcag tgtgctccca cctcagggcc ttgcctctgc ggcctccact tggaaagttc
     1741 tcagttccct ccaggcttct agaagcatct gggccagggc tcatggctgg ataatttccc
     1801 taggcttaac aacccaagca agcttcgcat cctcgtttta tttttggtta aacttatgaa
     1861 aatgtattaa gaaagagtgc agctcgagag agattcagag atggaacaca ccagacccca
     1921 gatcacaaag ccaaccatgc ccagcccctc ccagcacccc cagccccacg accatcgttc
     1981 tgaattctga cgacaccgtg agcctgcctt tgtacttcaa actcatggaa ggataaccac
     2041 cttcatgttt tgaaataaat gtttcctgtt gaaatga
//
