LOCUS       XM_047432270            5532 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens TBC1 domain family member 2B (TBC1D2B),
            transcript variant X5, mRNA.
ACCESSION   XM_047432270
VERSION     XM_047432270.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5532
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..5532
                     /gene="TBC1D2B"
                     /gene_synonym="NEDSGO"
                     /note="TBC1 domain family member 2B; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 5
                     mRNAs, 17 ESTs, 942 long SRA reads, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 93 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:23102"
                     /db_xref="HGNC:HGNC:29183"
                     /db_xref="MIM:619152"
     CDS             156..2357
                     /gene="TBC1D2B"
                     /gene_synonym="NEDSGO"
                     /codon_start=1
                     /product="TBC1 domain family member 2B isoform X4"
                     /protein_id="XP_047288226.1"
                     /db_xref="GeneID:23102"
                     /db_xref="HGNC:HGNC:29183"
                     /db_xref="MIM:619152"
                     /translation="MSSFRPGRGHNDSRRTVFYTNEEWELLDPTPKDLEESIVQEEKK
                     KLTPEGNKGVTGSGFPFDFGRNPYKGKRPLKDIIGSYKNRHSSGDPSSEGTSGSGSVS
                     IRKPASEMQLQVQSQQEELEQLKKDLSSQKELVRLLQQTVRSSQYDKYFTSSRLCEGV
                     PKDTLELLHQKDDQILGLTSQLERFSLEKESLQQEVRTLKSKVGELNEQLGMLMETIQ
                     AKDEVIIKLSEGEGNGPPPTVAPSSPSVVPVARDQLELDRLKDNLQGYKTQNKFLNKE
                     ILELSALRRNAERRERDLMAKYSSLEAKLCQIESKYLILLQEMKTPVCSEDQGPTREV
                     IAQLLEDALQVESQEQPEQAFVKPHLVSEYDIYGFRTVPEDDEEEKLVAKVRALDLKT
                     LYLTENQEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHT
                     RKFKDNTEPGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNV
                     LLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQ
                     VDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLY
                     EGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLISISFGDLNPF
                     PLRQIRNRRAYHLEKVRLELTELEAIREDFLRERDTSPDKGELVSDEEEDT"
ORIGIN      
        1 caggacttga caagtagcac cgcacctcca gcaaggctgt ccctcagctg caggccgtgt
       61 gggggtgtcc ctgctcttat ttctctttcc tgcattcacc ctttaggaac cagagctgag
      121 gagcacagtt tgacagctag ggcaaatgga attcgatgtc ttctttccgt cctgggagag
      181 gacataatga tagtcggagg actgtgtttt ataccaatga agagtgggaa cttttagacc
      241 caacccctaa ggacctagag gagtccatag tacaggaaga aaagaagaag ctgacccctg
      301 aaggaaacaa aggagtaact ggctcaggat tcccctttga ttttggacgt aacccctaca
      361 aaggaaagcg ccctttgaaa gacataattg ggtcgtacaa aaatcgtcac agcagtggtg
      421 acccttcaag tgaaggcaca tcaggcagtg gcagcgtcag catcaggaag ccggcctccg
      481 aaatgcaact gcaggtccag agccagcagg aagagctgga acagttaaag aaagacctgt
      541 ccagtcagaa ggagcttgtt cgactgctcc agcagacagt ccggtcatcc cagtatgaca
      601 agtatttcac aagcagccgg ctctgtgagg gggtcccaaa ggacacgctc gagcttctgc
      661 accaaaagga tgatcagatt ctgggcctta ccagccagct ggagaggttc agcttggaga
      721 aggagagtct tcagcaggaa gtaaggacgc tgaagagcaa agtgggcgag ctcaacgagc
      781 agctgggaat gctcatggag accatccaag ccaaggacga ggtcatcatc aagctcagcg
      841 agggcgaggg caacgggcct cctcccaccg tggcgcccag ctccccttcg gttgtgcctg
      901 ttgccaggga ccagctggaa ctggacaggc tgaaagataa tctacagggg tacaaaaccc
      961 aaaacaaatt tctaaataag gagattttgg aactctcagc tctacgaaga aatgcagaaa
     1021 ggagagagag ggatctgatg gcaaagtatt ctagcctgga agccaagctc tgccagatag
     1081 aaagtaaata cctgatattg ctccaagaaa tgaagacacc agtgtgctca gaagaccagg
     1141 ggcccacccg ggaggtcata gcccagttgc tggaggatgc tctgcaggtt gagagccaag
     1201 agcagccgga gcaagcattt gttaaacctc atcttgtcag tgaatatgat atttatgggt
     1261 tcaggactgt acctgaggat gatgaggaag agaaattggt tgccaaggtc cgcgcgttgg
     1321 atctgaagac tctctacctc acagaaaacc aggaagtctc cactggggtc aagtgggaaa
     1381 actattttgc aagtacagtg aacagggaga tgatgtgctc tccagagtta aaaaacctca
     1441 tccgtgcggg cattccccac gagcaccgtt ccaaggtgtg gaagtggtgt gtggaccgtc
     1501 acaccaggaa gttcaaggac aacactgagc ctggccactt ccagaccttg ctgcagaagg
     1561 cgctggagaa acagaaccca gcctccaagc agattgagct ggacttgctg cgaactctgc
     1621 ccaacaacaa acattactcc tgccccacct cagaaggcat acagaagtta cgcaatgtcc
     1681 tcctcgcctt ctcctggcgg aatccagata tcggctactg tcaaggccta aacaggttgg
     1741 tggcagtggc cctcctgtac ctggaacaag aagatgcttt ctggtgtctc gttaccatag
     1801 tggaagtttt catgcctcga gactattata caaagactct tttaggatcc caggtggacc
     1861 agcgggtgtt cagagacctt atgagtgaga agctgcctcg gttgcatggc cactttgaac
     1921 agtacaaagt cgactacact ctcatcactt tcaactggtt tctggtggta tttgtggata
     1981 gtgtcgttag tgacatcctc tttaaaatat gggactcttt cctttatgaa ggaccaaagg
     2041 ttattttccg ttttgctctg gcacttttta agtacaagga agaggagatt ttgaaattgc
     2101 aagattcgat gtctatattt aagtatctcc gctacttcac tcgcactatc cttgatgcta
     2161 ggaagctgat cagtatctcc tttggggacc tgaacccttt ccccctacgc cagatccgga
     2221 accgacgcgc ctaccacttg gagaaagtcc ggctggagct gaccgagctg gaggccatcc
     2281 gtgaggactt cctgcgtgag cgggacacca gccctgacaa gggtgagctg gtcagtgacg
     2341 aggaggagga tacctgagtg ggctcgggat gctgctcttc cttccttcac aaccaaagtg
     2401 tgcccaaagg gtgaaagtgc acttaaaagc cagaatgtaa cgtgtgtgtc ctctggggat
     2461 ctgctgggca gatgtcccaa gccaggctgc ccttcctcat ttcccactgt gcggggggca
     2521 ggggtgggag gtctaatctg tttacaacca tttccgtgcc atgcttttgg ttacacgtat
     2581 ctcagtcacg ctttctgcct ggttggtgga tcctcaggct taccagtggc tatttgcaag
     2641 agcctgtttc cagcctccgt cagcctgtcg gtgctctgac cctctgaaac cttgctttgc
     2701 tgggcatctc cccatattct ctctcctgta catagtgggc agtggtgtgt ggttttgaat
     2761 ggcagtgcta taaaggatgc cagctgtgct ttaggcacct gtaggccaga gggttgctgc
     2821 ctcaggcata aggttggtat gaaaaggggc tgccttagaa aagcaggcac atcccttgtt
     2881 cagaaatggc cactgtagga aagcctgtga acctcccacc agtggcttta agctgccagc
     2941 catgccccat ttctagaata gcctttgctc ttccacacgc aacccttcca tcagtgtctt
     3001 ccagcctgca tggggagggc ctggctgccc agacacccac cctcacttct catggccagc
     3061 ctgtgtttgc agatcactgg gctgctctgt ccccagcttg ccccgtgcca ggcatggctc
     3121 tgtgagattc tgtggaatgc ccttcttgac ttgtggaaat cattcaccaa gtacgatggg
     3181 atgggattcc aagtaaacag tggaccgtca tattgcaaag caggcccacg cctgggctgg
     3241 ccttggttga ggggatggag gaatgttttc gggggtgctt tgcagggcag tggtgcagcc
     3301 gcagcgtgaa cgctcttgga cagctgaaaa ccatggcctc cttggggatg gccagtgctc
     3361 ctggtgtctc cacctgcctg ggttgtgcag gaggccggct gccagtgcct ggggctggga
     3421 aacttttttg cttggggcag gcttgggtga gctctcccag atgtgtgccc accccaccac
     3481 tgcctggaac atccttgttc tctgccagga tgcaggggca ctgttgcctc tgacacagca
     3541 gtttctggga actcagagga ctgcctttct gaaggctggg gagaggcttt gagcaaggag
     3601 cttgtttttg cttaatcgct ctagaccatc cctgatgcgt agatgtgaga ggatgttttc
     3661 tggcacagtg ttatgaaaat acaagataaa tgatctcagt ggaatgtttc atattacccg
     3721 aaaaaaactg gaaatcatcc tttgttgtga acacactgag actaagaatt gaagcaatgc
     3781 agttttaaga agtatttttc ctattttttg ctgtcaactt tttggcaatg ccacggcaaa
     3841 gttggtgttt cagcacatgc tagagtgagc tccggcttcg tgtctttaac caactccact
     3901 aatgtttcac tgggtagacg gagctggcct ctatatttag ccagaagcct ttgcctcttt
     3961 tcaggcatca aaaatgggtt ttgtcattgt ctttgtcttt gagagcagca gtttgaggtc
     4021 tgactccttc agttgtcctg tgagctgggc gttgcagtct gctcgaatca agtgttggaa
     4081 ccccccccac ccctcagccc atcgtgaaac gacagctgtc agcctggggg gcggctgctg
     4141 aggaggtgca gcaggaatgg ggctgggccc tgaggtttta ctttccgagc caatggcccc
     4201 tggaacatgc cagcacacac tgccatgtcc tggggctaag agctgccttt agggacaggc
     4261 tcgtgttgtc cagtttgccc tgagagatgc acctgaccag gggcccgtcg tggctgcaac
     4321 ccacggtggt atgttagtgt ttccaggcag ttgtcagcag ctgccgggca gtgtgtgtgt
     4381 gcgacagcag gagagttcct ggaggaaagg gactggggac actttctcag aggttctcct
     4441 gcctggaatc aagtgatgcg tgtccagaag gcaagagagg gcggctccgc ctggttaaag
     4501 tttgggaacg ggacggagcc aactcctcct tccaggactg tgggccccac tcttttgcgc
     4561 taacacttcc cctccctcgg gtcactgagg aaagagctgc tctgtcccct ccagtgccct
     4621 gaaggtccct ggcctccact ggctgccatg gcagggggcc cttctgacag gggctgcccc
     4681 aagctgctgt tcctcctctg aaccttcacc ccaacaccca gcccgtggcc cctgcaaggg
     4741 ggaccctgcc agctgggaaa cccaaaggcc tgtccaaacg tgcgcaccag gaccgagggg
     4801 agctccctcc caacacctgc taggaattgc caacttttaa atggatgggg ttttttatgg
     4861 gttgaacctc tgttaatact tttgtacact ctcactacag tttatatttt tataggctat
     4921 tttctcaagg tgtttctaga ttccacatat ctattttata taacaagtta ttatgttatg
     4981 tgtgtgactc ccttgtgtgt atctgtgcca gcctcagcct ccgagttgct tttccctctg
     5041 gccctgactc tcactgactc accgatgtga tgtgcaggcc cacttcttac cccagatagc
     5101 ctcgggcgct gcctgtagtc atgctgacag ctgtacagta gccgccaaga ctgctgacag
     5161 ctggagacgg ttctggtttc aactacggta tattgatatc ggaagtattc tagacagatc
     5221 ctcggttggg ttttctagct acatgtttgt attgcacaga tccccacctg ccatcctata
     5281 gtgttgtctt cctgtgtgtt ccggggcttc tgggcagctg ggcctgcccg gggaagtcct
     5341 tgcaggtggg aggccataca gagacccact gtgtgccact gaacgtccca ctgctgctgg
     5401 gcaactggag gactgcaggg ggcgccaggt gactctctcc ttttatatca cagcagctcc
     5461 tgtgctgacc ttcaagttac gttttggaac tgtaatacta aaggaagaaa taaactacta
     5521 atttgtataa ta
//
