LOCUS       NM_001388465            1841 bp    mRNA    linear   PRI 16-FEB-2024
DEFINITION  Homo sapiens TBC1 domain family member 26 (TBC1D26), transcript
            variant 1, mRNA.
ACCESSION   NM_001388465
VERSION     NM_001388465.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1841)
  AUTHORS   Ishibashi,K., Kanno,E., Itoh,T. and Fukuda,M.
  TITLE     Identification and characterization of a novel Tre-2/Bub2/Cdc16
            (TBC) protein that possesses Rab3A-GAP activity
  JOURNAL   Genes Cells 14 (1), 41-52 (2009)
   PUBMED   19077034
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC005324.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.234647.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000437605.4/ ENSP00000410111.3
            RefSeq Select criteria :: based on manual assertion, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-102               AC005324.1         32641-32742         c
            103-243             AC005324.1         29955-30095         c
            244-319             AC005324.1         29602-29677         c
            320-402             AC005324.1         29346-29428         c
            403-442             AC005324.1         27502-27541         c
            443-523             AC005324.1         26948-27028         c
            524-631             AC005324.1         26638-26745         c
            632-741             AC005324.1         26195-26304         c
            742-790             AC005324.1         24877-24925         c
            791-890             AC005324.1         23804-23903         c
            891-985             AC005324.1         22989-23083         c
            986-1051            AC005324.1         22546-22611         c
            1052-1151           AC005324.1         22017-22116         c
            1152-1301           AC005324.1         21509-21658         c
            1302-1841           AC005324.1         20243-20782         c
FEATURES             Location/Qualifiers
     source          1..1841
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17p12"
     gene            1..1841
                     /gene="TBC1D26"
                     /note="TBC1 domain family member 26"
                     /db_xref="GeneID:353149"
                     /db_xref="HGNC:HGNC:28745"
     exon            1..102
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            103..243
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            244..319
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     CDS             245..1651
                     /gene="TBC1D26"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="TBC1 domain family member 26 isoform 1"
                     /protein_id="NP_001375394.1"
                     /db_xref="CCDS:CCDS92260.1"
                     /db_xref="GeneID:353149"
                     /db_xref="HGNC:HGNC:28745"
                     /translation="MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRK
                     YTNNLGIVHEMELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVI
                     PLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFI
                     QRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWALTQLLAVFY
                     SPNTAWLERLLSHQEQVLHKSFPKIMRHLGKEGLCIEGSMLTRLLRCFLDGKSFGLTL
                     RLWDVFILEGARVLTAMVHASFKIHRKHLMKLSWSTVWEFQERLSQSWALEDNAVLRN
                     LQTSMKELTKKHWDLPPPGSLLQNAHCYTIAWGLQSKAGKDSCTSRASGDFHAHPSQK
                     ALLNPGCHLPAQKRRNEGQPAADQSQKEMKCECMAFLTPRQNFGHKARLQLWPLTWTR
                     DAPMQAGVPWLLLTPSGS"
     exon            320..402
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            403..442
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            443..523
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            524..631
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            632..741
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            742..790
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            791..890
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            891..985
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1051
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1151
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1301
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1841
                     /gene="TBC1D26"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1820..1825
                     /regulatory_class="polyA_signal_sequence"
                     /gene="TBC1D26"
                     /note="hexamer: AATAAA"
     polyA_site      1841
                     /gene="TBC1D26"
                     /note="major polyA site"
ORIGIN      
        1 gtctctatgt ctggagctct tagagataag acatagaggt gtctggttct gagaaaagga
       61 agttttgcta agtgagagac acaactgact caactgactc agaaaactga ttatattcct
      121 ggtccctgaa cgatcctata gagacatcca gtccctgact ccacctgcct ccaggtgccc
      181 agaacagccc atcgtgggga cttcaccctc agcaagtgga cgccgtttgt cctgccaggg
      241 caggatggag atggatgggg acccgtataa cctgcctgcc caggggcaag gcaatatcat
      301 cattactaag tatgagcagg gacaccgagc tggggcagca gtggacttgg ggcatgagca
      361 ggttgatgtc agaaaataca ccaataacct cgggattgtg catgagatgg agctgcccca
      421 cgtcagtgcc ctggaggtga agcaaagacg caaggaaagt aaacgtacca acaagtggca
      481 aaagatgctt gcagactgga caaaatatag gagcaccaag aagctgtctc aaagagtata
      541 caaagtcatt cccctggcgg tacggggccg ggcgtggtca cttttgctag atattgacag
      601 aatcaagtcc cagaacccag gcaaatataa ggtcatgaag gagaagggca agaggtcctc
      661 cagaatcatc cactgcatcc agctagatgt cagccacacc ctgcagaaac acatgatgtt
      721 catacaaaga ttcggagtca agcagcagga attatgtgac atcctcgtgg cctattctgc
      781 atataaccct gaggtgggct accacaggga cctgagccgc atcactgcca tcctcctcct
      841 gtgtctgcca gaggaagatg ctttctgggc gcttacccag ttgctcgctg tattctacag
      901 cccaaatact gcctggctcg agaggctcct atcgcaccag gagcaggtgc tgcacaagtc
      961 cttcccaaag atcatgagac acctgggcaa ggaagggctg tgcattgagg gttccatgct
     1021 gacgaggctc ctccggtgtt tccttgatgg gaaatccttc gggctcaccc tgagactgtg
     1081 ggatgtgttc atcttggagg gcgcgcgggt actgacagcc atggtgcatg catcattcaa
     1141 aatacacagg aagcacctca tgaagctttc ctggagcact gtctgggagt ttcaggagcg
     1201 actctctcag agctgggccc tggaggacaa cgcggtcctc aggaaccttc aaacctctat
     1261 gaaggaactc acaaaaaaac actgggacct gccaccccca gggagcttgc tacaaaatgc
     1321 acattgctat accatagcct ggggcttgca atccaaggct ggcaaggatt cctgcacgtc
     1381 aagggcctca ggtgactttc atgcacaccc aagtcagaag gctctcctga atcctggatg
     1441 tcaccttcct gcccaaaaaa ggaggaacga gggtcaacca gcagcagacc agtcacaaaa
     1501 agagatgaaa tgtgagtgca tggccttcct gacacccaga caaaactttg ggcacaaagc
     1561 caggctgcag ctctggccac tgacttggac cagggatgcc cccatgcagg ccggtgtgcc
     1621 ctggctgctc ttgacaccct ctggctcctg acaccctctc ttcggctgcc tgcgttagga
     1681 agggagaacc tgccagtttt cagaagaaaa tgtagcttta ttataacata ggaaagactg
     1741 caagttatta cgggaggagg aggaggcctg aaacagctcc tgaaaatgag agggaaaagg
     1801 aaggtgtaaa tatgttggta ataaaatctc caaccacagc a
//
